Clinical trials: Blood Loss,
Post Partum Hemorrhage
Mostafa Maged Maneuveur to Prevent and Control Post-partum Haemorrhage During Normal Vaginal Delivery
PPH is commonly defined as blood loss exceeding 1000 milliliters after vaginal birth or cesarean section.1 PPH is often classified as primary/immediate/early (occurring within 24 hours of birth) or secondary/delayed/late…
- Trial name
- NCT05288322
- Testing
- Mostafa Maged maneuver
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Fayoum University
Systemic Lupus Erythematosus, Idiopahic Inflammatory Myopathies
A Study of CD19 UCAR-T Cells in Subjects With Autoimmune Diseases
The purpose of this study is to assess the safety and efficacy of CD19 UCAR-T cell therapy in Subjects with autoimmune diseases.
- Conditions
- Systemic Lupus Erythematosus, Idiopahic Inflammatory Myopathies, Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, Sjögren's Syndrome
- Trial name
- ET-902-AID01 (NCT07212322)
- Testing
- CD19 UCAR-T cells
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Behcet's Disease, Churg-Strauss Syndrome
Educational Needs of Patients With Systemic Vasculitis
A cross-sectional study design and online questionnaire was used to assess the informational needs of patients with several different types of systemic vasculitis.
- Conditions
- Behcet's Disease, Churg-Strauss Syndrome, Vasculitis, Central Nervous System, Giant Cell Arteritis
- Trial name
- NCT02190929
- Where
- United States
- Volunteers
- 386 people
- Sponsor
- University of South Florida
Central Venous Catheterization
Comparison of the Oblique-axis and Long-axis Approaches for Axillary Vein Catheterization Under Ultrasound Guidance
Ultrasound-guided axillary vein catheterization can be performed via the oblique-axis and long-axis approaches of the axillary vein.
- Trial name
- NCT04962945
- Testing
- Oblique-axis approach group, Long-axis approach group
- Where
- China
- Volunteers
- 194 people
- Sponsor
- Guowei Tu
Primary Immune Thrombocytopenia
Study of CM313 (SC) Injection in Subjects With Primary Immune Thrombocytopenia (ITP)
This is a randomized, double-blind, placebo-controlled study evaluating the safety, tolerability, pharmacokinetics, pharmacodynamics, immunogenicity, and initial efficacy of CM313 (SC) injection in patients with primary immune…
- Trial name
- NCT06594146
- Testing
- CM313 injection
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Keymed Biosciences Co.Ltd
Intracerebral Hemorrhage
Efficacy and Safety of Minocycline in the Treatment of Intracerebral Hemorrhage
This study plans to enroll 1248 patients with supratentorial ICH within 24 hours of onset across multiple stroke centers. After randomization, the control group will only receive medical therapy.
- Trial name
- NCT07305896
- Testing
- Minocycline
- Volunteers
- 1,248 people
- Sponsor
- The First Hospital of Jilin University
Pneumothorax Iatrogenic Postprocedural, Air Embolism as A Complication of Medical Care
Complications After CT-guided Lung Biopsies at St. Olavs Hospital
At St. Olavs Hospital, a prospective collection of data on complications related to CT-guided lung biopsies has been conducted over several years as part of quality control study.
- Conditions
- Pneumothorax Iatrogenic Postprocedural, Air Embolism as A Complication of Medical Care, Hemoptysis
- Trial name
- KELSO (NCT07528170)
- Testing
- CT-guided needle biopsy of lung nodule
- Volunteers
- 1,200 people
- Sponsor
- St. Olavs Hospital
Bronchopulmonary Dysplasia, Necrotizing Enterocolitis
Effects of Delayed Cord Clamping in Very Low Birth Weight Infants
The purpose of this study was to see if a brief delay in cord clamping for 30 to 45 seconds would result in higher hematocrit levels, fewer transfusions, healthier lungs, and better motor function at 40 wks and 7 months of age.
- Conditions
- Bronchopulmonary Dysplasia, Necrotizing Enterocolitis, Intraventricular Hemorrhage, Late Onset Neonatal Sepsis
- Trial name
- NCT00840983
- Testing
- delayed cord clamping
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Rhode Island
Frailty, Acute Coronary Syndrome
Role of Frailty in Bleeding Risk Prediction in Acute Coronary Syndrome
Studying the incremental role of frailty in predicting in-hospital, short-term (30 days), and mid-term (6 months) bleeding in ACS patients.
- Conditions
- Frailty, Acute Coronary Syndrome, Bleeding
- Trial name
- NCT07158788
- Volunteers
- 850 people
- Sponsor
- Assiut University
Intracerebral Haemorrhage in Cerebellum
Vitamin K1 in the Treatment of Spontaneous Intracerebral Hemorrhage
In order to determine the effectiveness and safety of early vitamin K1 use in reducing the risk of bleeding and improving prognosis in patients with spontaneous intracerebral hemorrhage.
- Trial name
- NCT03388970
- Testing
- Vitamin K 1, normal saline
- Where
- 5 sites in China
- Volunteers
- 400 people
- Sponsor
- HUANG XIANJIAN
Polyp of Large Intestine, Colonic Polyps
Efficacy and Safety of a New Polypectomy Snare for Cold-polypectomy for Small Colorectal Polyps
Colorectal cancer is a major cause of morbidity and mortality in Western countries. Scientific studies have shown that endoscopic polypectomy is efficacious in preventing CRC incidence and mortality.
- Conditions
- Polyp of Large Intestine, Colonic Polyps, Colon Nos Polypectomy Tubular Adenoma, Complications
- Trial name
- NCT02245854
- Testing
- Exacto™
- Where
- 3 sites in Italy
- Volunteers
- 250 people
- Sponsor
- Istituto Clinico Humanitas
Heart Surgery, Blood Loss, Surgical
Fresh Frozen Plasma in Cardiac Surgery: Descriptive and Prognostic Study
Despite experts' recommendations, the consumption of Fresh frozen plasma (FFP) is very heterogeneous among French cardiac surgery centers.
- Trial name
- PLASMACARD (NCT00221741)
- Testing
- Fresh Frozen Plasma (blood product)
- Where
- France
- Volunteers
- 1,497 people
- Sponsor
- University Hospital, Bordeaux
Immune Thrombocytopenia
Reposition of Second Line Treatment in Chronic Immune Thrombocytopenia
Hydroxychloroquine has been reported to have a clinically significant effect on the platelet count in systemic lupus thrombocytopenia. Its action may be due to its immune modulator effect.
- Trial name
- NCT03229746
- Testing
- Hydroxychloroquine, vincristine, azathioprine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Menorrhagia
The Effect of Post Ablation Medroxyprogesterone Acetate on Endometrial Amenorrhea Rates
Heavy menstrual bleeding are a common reason for consultation in gynecology and are defined by International Federation of Gynecology and Obstetrics as the perception of menstrual volume increased regardless of the frequency…
- Trial name
- MPA postAE (NCT02449161)
- Testing
- MPA
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Guy Waddell
Tracheostomy Complication, Tracheostomy Infection
The Ultrasound-guided vs Bronchoscopy-guided vs Ultrasound-bronchoscopy-guided Percutaneous Tracheostomy Trial
This trial (BRONCUS) is a randomized one designed to evaluate the overall safety of ultrasound guided compared to bronchoscopy guided compared to ultrasound-bronchoscopy guided percutaneous tracheostomy, in order to find out if…
- Conditions
- Tracheostomy Complication, Tracheostomy Infection, Tracheostomy Hemorrhage
- Trial name
- BRONCUS-PDT (NCT06226142)
- Testing
- Percutaneous dilatational tracheostomy
- Where
- Romania
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Peptic Ulcer
Efficacy of Proton Pump Inhibitor in Prevention of Clopidogrel-related Peptic Ulcer
Proton Pump Inhibitors (PPI) can prevent the recurrence of peptic ulcer in clopidogrel users.
- Trial name
- NCT01138969
- Testing
- esomeprazole
- Where
- Taiwan
- Volunteers
- 165 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Blood Loss Massive, Trauma
Evaluation of the Clinical Performance of the Quantra System With the QStat Cartridge in Trauma
This pilot study will evaluate the performance of the Quantra System comprised of the Quantra Hemostasis Analyzer with the QStat Cartridge in trauma patients.
- Trial name
- NCT03934983
- Testing
- Quantra System
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- HemoSonics LLC
Postpartum Haemorrage Sever Bleeding After Delivery
Efficacy of Tranexamic Acid In Reducing Blood Loss During Cesarean Section Because Of Placenta Previa
This study evaluate role of tranexamic acid in reducing blood loss among pregnant women undergoing cesarean section because of placenta previa .Half of participants will receive tranexamia acid drug While the other half will…
- Trial name
- NCT02688127
- Testing
- Tranexamic Acid
- Volunteers
- 52 people
- Sponsor
- Medical Research Council
Focal Segmental Glomerulosclerosis, Minimal Change Disease
Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases
To evaluate the safety, efficacy and tolerability of sparsentan oral suspension and tablets, and assess changes in proteinuria after once-daily dosing over 108 weeks.
- Conditions
- Focal Segmental Glomerulosclerosis, Minimal Change Disease, Immunoglobulin A Nephropathy, IgA Vasculitis
- Trial name
- EPPIK (NCT05003986)
- Testing
- Sparsentan
- Where
- 47 sites in United States, Germany and 6 more
- Volunteers
- 67 people
- Sponsor
- Travere Therapeutics, Inc.
Nasal Surgery, Anesthesia
Remifentanil vs. Nicardipine for Controlled Hypotension in Elective Nasal Surgery
This study compares remifentanil infusion versus nicardipine infusion for controlled hypotension during elective nasal surgery. Both agents are standard clinical methods.
- Conditions
- Nasal Surgery, Anesthesia, Controlled Hypotension for Nasal Surgeries
- Trial name
- NCT07660562
- Testing
- Nicardipine, Remifentanil
- Volunteers
- 44 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
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