Clinical trials: Blood Loss,
Gastrointestinal Bleeding
Efficacy of Wireless Capsule Endoscopy and CT Enterography in Obscure Gastrointestinal Bleeding
The purpose of this study is to compare the efficacy between video capsule endoscopy and CT enterography in diagnosis of obscure gastrointestinal bleeding.
- Trial name
- NCT02219568
- Testing
- CT enterography, video capsule endoscopy
- Where
- Thailand
- Volunteers
- 52 people
- Sponsor
- Mahidol University
Peptic Ulcer With Haemorrhage
Efficacy of Vonoprazan Versus Intravenous Proton Pump Inhibitors for Prevention of Rebleeding in High Risk Peptic Ulcers Bleeding After Successful Endoscopic Hemostasis
Upper gastrointestinal hemorrhage (UGIH) is common urgency condition.The estimate mortality rate about 7 percent from peptic ulcers disease(PUD).
- Trial name
- NCT05005910
- Testing
- Vonoprazan, PPIs IV infusion
- Where
- Thailand
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Uayporn Kaosombatwattana
Cerebrovascular Disease, Ischemic Stroke
Florida Cerebrovascular Disease Biorepository and Genomics Center
The purpose of this study is to create a state-wide biorepository and resource center for cerebrovascular diseases in Florida, which will include collecting medical history information and blood from subjects affected by…
- Conditions
- Cerebrovascular Disease, Ischemic Stroke, Transient Ischemic Attack, Intracerebral Hemorrhage
- Trial name
- NCT05491980
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Mayo Clinic
Upper Gastrointestinal Bleeding
Risk Stratification of Patients Presenting With Upper Gastrointestinal Bleeding to the Emergency Department Using AIMS65 Score and Red Cell Distribution Width
The rationale of this study in UGIB patients is to assess whether the prediction of mortality and morbidity using AIMS65 score improves when used in combination with RDW in the emergency department setting.
- Trial name
- RUGBE (NCT04825977)
- Testing
- RISK STRATIFICATION USING AIMS65 SCORE AND RDW
- Where
- India
- Volunteers
- 348 people
- Sponsor
- Jubilee Mission Medical College and Research Institute
Thrombotic Thrombocytopenic Purpura
Use of Rituximab Treatment in Addition to Standard Care for Newly Presenting Thrombotic Thrombocytopenic Purpura
The purpose is to evaluate safety and feasibility of the use of Rituximab as an adjunct to standard therapy (plasmapheresis + steroids) for patients with thrombotic thrombocytopenic purpura (TTP).
- Trial name
- NCT00251277
- Testing
- Rituximab
- Where
- United States
- Sponsor
- Weill Medical College of Cornell University
Benign Neoplasm of Stomach, Malignant Neoplasm of Stomach
Surgicel® Fibrillar for Delayed Bleeding After ESD
The aim of this study is to assess the effect of Surgicel® Fibrillar as adjuvant treatment to H2RA on preventing ulcer bleeding after ESD for gastric epithelial tumors
- Trial name
- NCT01758965
- Testing
- PPI, H2RA and surgicel
- Where
- South Korea
- Volunteers
- 146 people
- Sponsor
- Soonchunhyang University Hospital
Cerebral Vasospasm
The Intra-arterial Vasospasm Trial
The primary objective of the study is to determine the optimal intra-arterial drug treatment regimen for arterial lumen restoration post cerebral vasospasm following aneurysmal subarachnoid hemorrhage.
- Trial name
- iVAST (NCT01996436)
- Testing
- Nicardipine, Verapamil, Nicardipine + Verapamil + Nitroglycerin
- Where
- 5 sites in United States
- Volunteers
- 92 people
- Sponsor
- Peng Roc Chen, MD
Lung Cancer, Postoperative Pain
Comparison of Robot Assisted Thoracic Surgery With Video Assisted Thoracic Surgery in Case of Lung Cancer
In this study the investigator will compare the effectiveness of robot assisted thoracic surgery (RATS) with video assisted thoracic surgery (VATS) in case of lung cancer.
- Conditions
- Lung Cancer, Postoperative Pain, Blood Loss, Inflammatory Response
- Trial name
- NCT03152071
- Testing
- Robot assited thoracic surgery, Video assited thoracic surgery
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Universitair Ziekenhuis Brussel
Peptic Ulcer Hemorrhage
Resolution Endoclips Vs Epinephrine Injection and Heater Probe
To compare the efficacy of a novel endoscopic clipping device(Resolution Clip™) and conventional epinephrine injection and heater probe thermocoagulation in control of peptic ulcer bleeding and prevention of recurrent bleeding
- Trial name
- NCT00165009
- Testing
- Resolution clip (endo-clipping device)
- Where
- China
- Volunteers
- 103 people
- Sponsor
- Chinese University of Hong Kong
Traumatic Brain Injury, Hemorrhage
Fibrinogen Concentrate in Isolated Traumatic Brain Injury
Fibrinogen is a unique precursor of fibrin and cannot be compensated for by other coagulation factors. If plasma fibrinogen concentrations are insufficient, hemostatic clots cannot be formed with the appropriate firmness.
- Trial name
- NCT03304899
- Testing
- RiaSTAP Injectable Product
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Leila Dehghani
Heavy Menstrual Bleeding
Impact of Incomplete Endometrial Ablation
The aim of the proposed protocol is to study the impact of incomplete endometrial ablation on the PBAC score, reintervention, satisfaction, controlled bleeding and dysmenorrhea at 24 months after Novasure endometrial ablation, in…
- Trial name
- NCT06122363
- Testing
- hysteroscopy
- Where
- Netherlands
- Volunteers
- 121 people
- Sponsor
- Maxima Medical Center
Uterine Atony, Post-partum Hemorrhage
Comparison of Two Doses of Carbetocin for Prevention of Uterine Atony, During Elective Cesarean Section
The purpose of this study is to evaluate the effectiveness of two doses of carbetocin (50 mcg vs 100 mcg) in preventing uterine atony during elective cesarean section.
- Trial name
- NCT01630187
- Testing
- Carbetocin
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- Laval University
Haemophilia
National Survey of People With Haemophilia in Portugal
The purpose of this study is to implement a national survey to collect information regarding Portuguese people with haemophilia (PWH) on socio-demographic, clinical and psychosocial factors.
- Trial name
- NCT02870114
- Where
- Portugal
- Volunteers
- 146 people
- Sponsor
- University of Minho
Hemorrhage, Sepsis
Compensatory Reserve Index as a Hemodynamic Status Evaluation Tool in Patients
The investigators will use the Compensatory Reserve Index (CRI) device to monitor hemodynamic status of patients in the hospital.
- Trial name
- CRIHEM (NCT02701725)
- Testing
- CRI status
- Volunteers
- 600 people
- Sponsor
- Meir Medical Center
Uterine Fibroid
The Efficacy and Safety of Preoperative Misoprostol in Blood-loss Reduction During Myomectomy.
Open myomectomy remains the principal treatment for symptomatic fibroids in sub-Saharan countries irrespective of fertility desires.
- Trial name
- MM (NCT03509168)
- Testing
- Misoprostol Pfizer Brand, Non-insertion of Misoprostol Pfizer Brand
- Where
- Uganda
- Volunteers
- 46 people
- Sponsor
- Makerere University
Postpartum Hemorrhage
Carbetocin Versus Oral Tranexamic Acid Plus, Buccal Misoprostol on Blood Loss After Vaginal Delivery
Excessive bleeding at or after childbirth accounts for about half of all the post-partum maternal deaths in developing countries and is the single most important cause of maternal mortality worldwide.
- Trial name
- NCT03708497
- Testing
- carbetocin, Tranexamic acid plus misoprostol, misoprostol
- Where
- 2 sites in Egypt
- Volunteers
- 360 people
- Sponsor
- Aswan University Hospital
Menorrhagia, Pelvic Pain
Randomized Clinical Trial Comparing Conventional Laparoscopic and Robot-Assisted Laparoscopic Hysterectomy
Robotic-assisted surgery is becoming more prominent within the specialty of Gynecologic surgery with little direct evidence that it is if not better than traditional laparoscopic surgery, at least equivalent.
- Conditions
- Menorrhagia, Pelvic Pain, Hysterectomy
- Trial name
- NCT02118974
- Testing
- Hysterectomy
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Milton S. Hershey Medical Center
Blood Loss
Comparison of Three Methods of Hemoglobin Monitoring
The purpose of this study is to compare the hemoglobin results obtained with 1) the HemoCue™, 2) the Masimo SpHb™, and 3) the UCSF Clinical Laboratory.
- Trial name
- NCT00792597
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Acute Myocardial Infarction (AMI), Gastrointestinal Bleeding
Routine Use of Potassium Competitive Acid Blocker vs. Guideline-Directed Gastrointestinal Protection Strategy in Acute Myocardial Infarction
This study aims to compare the clinical outcomes between routine use of potassium competitive acid blocker (P-CAB) and guideline-directed gastrointestinal (GI) protection strategy in patients with acute myocardial infarction…
- Trial name
- PCAB-AMI (NCT07467213)
- Testing
- Zastaprazan, Proton Pump Inhibitors (PPI)
- Where
- South Korea
- Volunteers
- 5,000 people
- Sponsor
- Samsung Medical Center
Hemophilia A
An Open Label Study to Determine the Safety and Efficacy of Replacement Factor VIII Protein (Known as rFVIIIFc) in Previously Untreated Males With Severe Hemophilia A
The primary objective of the study was to evaluate the safety of rFVIIIFc (BIIB031) in previously untreated participants (PUPs) with severe hemophilia A.
- Trial name
- NCT02234323
- Testing
- rFVIIIFc
- Where
- 71 sites in United States, Australia and 12 more
- Volunteers
- 108 people
- Sponsor
- Bioverativ, a Sanofi company
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