Clinical trials: Blood Loss, Surgical
Blood Loss, Surgical
B-lynch Transverse Compression Suture
Is B-Lynch transverse compression suture safe and effective in controlling excessive blood loss during conservative management of women with placenta previa?
- Trial name
- NCT06359886
- Testing
- B-Lynch Transverse Compression Suture
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Alexandria University
Lung Transplant, Complications Surgical
Protest Trial: TXA vs Saline
To determine if endobronchial (topical) tranexamic acid used prophylactically prior to performing transbronchial biopsies in lung transplant recipients reduces bleeding risk.
- Trial name
- NCT06422273
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Corewell Health West
Surgical Wound
Angiography Combination Laparoscopy in Patients With Obscure Gastrointestinal Bleeding
There were many approaches for patients with obscure gastrointestinal bleeding (OGIB). Capsule endoscopy (CE), double-balloon endoscopy, deep small-bowel spiral enteroscopy, laparoscopy, computed tomography and angiography have…
- Trial name
- NCT02069262
- Testing
- rebleeding
- Where
- China
- Volunteers
- 66 people
- Sponsor
- The Second People's Hospital of GuangDong Province
Spinal Deformity, Degenerative Lumbar Spinal Stenosis
Tranexamic Acid in Adult Spinal Deformity Surgery
Posterior spinal surgery for adult deformity is associated with high incidence of blood loss and need for blood transfusion and intraoperative blood salvage, with associated increased cost and risk for perioperative…
- Conditions
- Spinal Deformity, Degenerative Lumbar Spinal Stenosis, Blood Loss, Surgical
- Trial name
- NCT03553186
- Testing
- Tranexamic Acid 100 MG/ML
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Hospital for Special Surgery, New York
Endoscopic Coblation Adenoidectomy
Coblation and Traditional Adenoidectomy: A Comparative Study
Adenoidectomy is a common pediatric otolaryngologic procedure. While cold curettage remains widely practiced, endoscopic coblation has been developed to enhance precision, minimize intraoperative complications, and reduce…
- Trial name
- NCT07417007
- Testing
- Cold Curettage Adenoidectomy, Coblation-Assisted Adenoidectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Medipol University
Off Pump Coronary Artery Bypass Surgery
Tranexamic Acid in Off-pump Coronary Surgery
The aim of this prospective, randomized, double-blinded, placebo-controlled study was to evaluate the effects of tranexamic acid, a synthetic antifibrinolytic drug, on the postoperative bleeding and transfusion requirements in…
- Trial name
- TAOPCAB (NCT01064167)
- Testing
- Tranexamic Acid
- Where
- China
- Volunteers
- 231 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Post Operative Hemorrhage, Transfusion Related Complication
Monitoring Noninvasively for Infusion and Transfusion Optimization
This is a multicenter, cluster randomized controlled trial to assess the effects of an optimized intraoperative fluid and blood management strategy on postoperative complications.
- Conditions
- Post Operative Hemorrhage, Transfusion Related Complication, Blood Transfusion Associated Adverse Reactions, Hypovolemia
- Trial name
- NCT04388722
- Testing
- Pulse CO-Oximeter Sensor
- Sponsor
- Masimo Corporation
Bleeding, Healing Surgical Wounds
Effect of Inula Viscosa Extract on Postoperative Bleeding and Healing After Lower Third Molar Surgery
In oral surgery, the operation of the impacted third molar is one of the most common surgical procedures performed by oral and maxillofacial surgeons .Several attempts have been made to reduce the postoperative outcome of the…
- Trial name
- NCT06947603
- Testing
- inula viscosa extract, no inula viscosa extract
- Where
- Syria
- Volunteers
- 30 people
- Sponsor
- Al-Wataniya University
Stroke
Can Acupuncture Benefit Surgical Patients With Haemorrhagic Stroke?
The purpose is to establish whether acupuncture in addition to conventional rehabilitation programme can improve the functional outcome and quality of life of surgical patients with haemorrhagic stroke, as compared to…
- Trial name
- NCT01037894
- Testing
- Acupuncture, Conventional rehabilitation
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Chinese University of Hong Kong
Chronic Subdural Hematoma, Subdural Hematoma
Non-Thermal Plasma to Reduce Recurrence in Chronic Subdural Hematoma
The goal of this randomized controlled trial is to evaluate whether the adjuvant application of non-thermal plasma (NTP) during standard surgical drainage of chronic subdural hematoma (cSDH) can reduce the recurrence rate at 6…
- Conditions
- Chronic Subdural Hematoma, Subdural Hematoma, Recurrence, Postoperative Complications
- Trial name
- NCT07656818
- Testing
- Standard Surgery Protocol, Non-Thermal Plasma
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Benjamín Gonzalo Rodríguez Méndez
Intraoperative Bleeding
Comparison Between Atenolol,Propnalol and Ivabradine
The aim of this work is to compare atenolol, propranolol, and ivabradine as a premedication to achieve bloodless field anesthesia primarily controlling heart rate in lumbar spine surgery.
- Trial name
- NCT06670690
- Testing
- Atenolol 50 MG, Propranolol Pill, Ivabradine
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Secondary Post Tonsillectomy Hemorrhage, Primary Post Tonsillectomy Hemorrhage
Safety Study of Post Tonsillectomy Ibuprofen Use in Adults
The purpose of this study is to determine if ibuprofen use after electrocautery tonsillectomy increases the post-tonsillectomy hemorrhage rate.
- Trial name
- NCT01837810
- Testing
- Ibuprofen
- Where
- 3 sites in United States
- Volunteers
- 810 people
- Sponsor
- Brooke Army Medical Center
Chronic Periodontitis
Photodynamic Therapy Associated With Full-mouth Ultrasonic Debridement in the Treatment of Severe Chronic Periodontitis
Background: Photodynamic therapy (PDT) is a method of microbial reduction which can benefit periodontal treatment in areas of difficult access, such as deep pockets and furcations.
- Trial name
- NCT01535690
- Testing
- photodynamic therapy and periodontal debridement
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Escola Bahiana de Medicina e Saude Publica
Periapical Lesion
Effect of Piezoelectric Device on Intraoperative Hemorrhage Control and Quality of Life
Most osteotomies and apicoectomies in periapical surgeries are performed by surgical carbide or diamond burs. But greater pressure is applied during cutting which causes more thermal and mechanical damage to the bone.
- Trial name
- NCT06240182
- Testing
- conventional surgery, piezoelectric device
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Surgical Blood Loss, Hemorrhage
The Cryopreserved vs. Liquid Platelets Trial
This trial is a phase III multicentre blinded randomised controlled clinical non-inferiority trial of cryopreserved platelets vs. conventional liquid-stored platelets for the management of surgical bleeding.
- Trial name
- CLIP II (NCT03991481)
- Testing
- Cryopreserved platelets, Liquid-stored platelets
- Where
- 6 sites in Australia
- Volunteers
- 388 people
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Pancreatectomy, Complication of Surgical Procedure
Pancreaticoduodenectomies With Complete Arterial Coverage by Retromesenteric Omentoplasty
To assess the efficacy of complete covering using retromesenteric omentoplasty vs. partial covering or no covering of peripancreatic arteries in decreasing incidence of grade B+C post-pancreatectomy hemorrhage (PPH), i.e.
- Trial name
- PACOMARCO (NCT05992857)
- Testing
- Pancreaticoduodenectomy without retromesenteric omental flap, Pancreaticoduodenectomy with retromesenteric omental flap
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Blood Loss, Surgical
Retransfusion or Not of Cardiotomy Blood
This randomised controlled trial has a non-inferiority design. The aim is to test if the blood loss (volume in mL and hemoglobin) is effected by heart and lung cardiotomy retransfusion, or not? Forty CABG (Coronary Artery By pass…
- Trial name
- NCT04574128
- Testing
- No retransfusion of cardiotomy blood
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Örebro University, Sweden
Blood Loss, Surgical, Intraoperative Complications
Prospective Double-blind Study for the Use of Aspirin During Transurethral Surgery of the Bladder or the Prostate
Aspirin is very common in older patients. Therefore many of the investigators patients have aspirin. The aim of the study is to proof that Transurethral Surgery of the bladder or the prostate can be performed with aspirin.
- Conditions
- Blood Loss, Surgical, Intraoperative Complications, Re-operation Rates in Patients With Aspirin Treatment
- Trial name
- NCT00861367
- Testing
- transurethral surgery with or without aspirin
- Where
- Switzerland
- Sponsor
- University Hospital, Basel, Switzerland
Cardiovascular Procedures, Thoracic Aortic Aneurysm
Post Market Surveillance Study Evaluating BioFoam Surgical Matrix in Cardiovascular Surgery
This is a prospective, multicenter, single-arm study designed to collect clinical data to support the safety and effectiveness of BioFoam used as a surgical adjunct to anastomotic hemostasis following cardiovascular surgery.
- Conditions
- Cardiovascular Procedures, Thoracic Aortic Aneurysm, Aortic Valve Replacement, Type A Aortic Dissection
- Trial name
- NCT02164201
- Where
- 2 sites in Germany, Italy
- Volunteers
- 75 people
- Sponsor
- CryoLife Europa
Chest Tube Output, Allogeneic Blood Transfusions
Algorithm-Guided Transfusions in Cardiac Surgery Patients for Reduction of Drainage Blood Losses
Cardiac surgery patients have a risk to need allogeneic blood transfusions that depends on several risk factors, e.g. the type of surgery, concomitant medication with anticoagulants, and postoperative chest tube output.
- Trial name
- HEART-PoC (NCT01402739)
- Testing
- Point of Care Coagulation Monitoring Guided Transfusion Algorithm, standard coagulation monitoring guided transfusion algorithm
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Michael Sander