Clinical trials: Blood Loss, Surgical
Blood Loss
Comparison of Three Methods of Hemoglobin Monitoring
The purpose of this study is to compare the hemoglobin results obtained with 1) the HemoCue™, 2) the Masimo SpHb™, and 3) the UCSF Clinical Laboratory.
- Trial name
- NCT00792597
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Bleeding, Surgical Blood Loss
Decreasing Postoperative Blood Loss by Topical vs. Intravenous Tranexamic Acid in Open Cardiac Surgery
The aim is to conduct a double-blinded single-centre randomized controlled clinical trial of application of topical dose of tranexamic acid (TA) versus the usual intravenous TA in patients undergoing cardiac surgery at the…
- Trial name
- DEPOSITION (NCT03376061)
- Testing
- Tranexamic Acid
- Where
- Canada
- Volunteers
- 97 people
- Sponsor
- Population Health Research Institute
Surgical Bleeding
A Safety and Efficacy Study Comparing Fibrocaps and Tachosil in Hepatic Surgery
The primary objective of the study is to demonstrate the non-inferiority or superiority of Fibrocaps plus gelatin sponge compared to Tachosil when control of mild to moderate bleeding with conventional surgical techniques is…
- Trial name
- NCT02284256
- Testing
- Fibrocaps, TachoSil
- Where
- 15 sites in Austria, Germany
- Volunteers
- 150 people
- Sponsor
- Mallinckrodt
Blood Loss, Surgical, Blood Loss
Estimated Blood Loss: Novel Model for Estimating Surgical Blood Loss.
Estimated blood loss is an important parameter recognized as a standard practice in anesthesiology and others medical specialties, with relevant clinical and research applications.
- Conditions
- Blood Loss, Surgical, Blood Loss, Blood Loss, Postoperative
- Trial name
- NCT03249038
- Testing
- Measurement of external blood loss, Serum Hemoglobin concentration
- Volunteers
- 100 people
- Sponsor
- Hospital Clinic of Barcelona
Cystoscopic Surgical Procedures, Pain
Physicians' Perception About Patient Pain in Flexible Cystoscopy With Local Anesthesia
Cystoscopy with local anesthesia is commonly performed for the follow-up of bladder cancer, evaluation of hematuria, assessment of urethral strictures, and examination of the lower urinary tract.
- Trial name
- NCT06944314
- Testing
- Diagnostic procedures, Flexible Cystoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Marmara University
Intraoperative Bleeding
The Value of Tranxemic Acid to Reduce Intraoperative Blood Loss During Elective Cesarean Sections in High Risk Women
A full medical history will be obtained from all participants. Obstetric ultrasonography and laboratory tests will be performed.According to group assignment, either 1 g(10 mL) tranexamic acid stored in a dry container at 15…
- Trial name
- NCT03820206
- Testing
- Tranexamic Acid, Cesarean section
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Cairo University
Intraoperative Bleeding
Tranexamic Acid Versus Epinephrine During Exploratory Tympanotomy
Exploratory tympanotomy is surgical access to the middle ear, made for diagnosis and management of unexplained conductive hearing loss, performed under an oto-microscope across the external auditory canal after tympanic membrane…
- Trial name
- NCT04188184
- Testing
- Tranexamic Acid, Epinephrine
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Maxilla Fracture, Malunited Maxilla Fracture
The Aim of This Study is to Compare the Outcome of Piezosurgery Versus Conventional Osteotomy in Maxillary Old Malunited Fractures in Terms of Intraoperative Blood Loss and Duration of Surgery..
To compare the outcomes of piezosurgery and conventional osteotomy in Le Fort I osteotomy for old malunited maxillary fractures in terms of mean duration of surgery and intraoperative blood loss.
- Trial name
- NCT07730320
- Testing
- PIEZO ELECTRIC DEVICE (PIEZOSURGERY), GROUP B CONVENTIONAL METHOD ( Mallet and OSTEOTOME
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Allama Iqbal Medical College
Blood Transfusion, Blood Transfusion, Autologous
A Study to Determine the Effectiveness of Epoetin Alfa in Facilitating Self-donation of Blood Before Surgery in Non-anemic Patients Who Are Undergoing Orthopedic, Heart and Blood Vessel, or Breast Reduction Surgery; Performed in Combination With a Procedure to Reduce Blood Loss During Surgery.
The purpose of this study is to determine the safety and effectiveness of epoetin alfa and whether epoetin alfa will enable self-donation of blood during an 11-day period before surgery (which is shorter than the conventional…
- Conditions
- Blood Transfusion, Blood Transfusion, Autologous, Orthopedic Procedures, Orthopedic Surgery
- Trial name
- NCT00270023
- Testing
- epoetin alfa
- Volunteers
- 112 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Hypofibrinogenemia, Surgical Blood Loss
Effectiveness of Different Fibrinogen Preparations in Restoring Clot Firmness
Fibrinogen concentrate is produced by different manufacturers using different purification technologies. The products available in Italy are three: RiaSTAP (CSL Behring), FIBRYGA (Octapharma), and FibCLOT (LFB).
- Conditions
- Hypofibrinogenemia, Surgical Blood Loss, Bleeding, Cardiac Disease
- Trial name
- EDIPORE (NCT05780125)
- Testing
- FibCLOT, RiaSTAP
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- IRCCS Policlinico S. Donato
Blood Loss, Surgical
Immunogenicity and Safety Study of rThrombin in Surgical Hemostasis
The objective of this study is to assess the immunogenicity and safety of recombinant Thrombin (rThrombin) in patients with prior rThrombin exposure.
- Trial name
- NCT00813904
- Testing
- rThrombin, 1000 IU/mL
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- ZymoGenetics
Surgery, Blood Loss, Surgical
Investigation of the Transfusion Practices in Surgical Patients in Turkey
The aim of this study is to describe the transfusion practices in patients undergoing major surgery in Turkey. The transfusion rates of red blood cells (RBC), fresh frozen plasma (FFP) and platelets; the transfusion predictors…
- Conditions
- Surgery, Blood Loss, Surgical, Blood Loss Anemia, Blood Transfusion
- Trial name
- CeKATU (NCT03468738)
- Testing
- Blood transfusion
- Where
- 61 sites in Turkey (Türkiye)
- Volunteers
- 6,481 people
- Sponsor
- Diskapi Teaching and Research Hospital
Morbid Obesity
Efficiency of TISSEEL for Sleeve Gastrectomy Complications
Laparoscopic Sleeve Gastrectomy has emerged over the last 20 years as a treatment of choice in the surgical management of patients with morbid obesity.
- Trial name
- TISSEEL (NCT01613664)
- Testing
- tisseel, no tisseel
- Where
- 2 sites in France
- Volunteers
- 597 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Thoracic Surgery, Vascular Injury
Major Vascular Injuries in Elective Thoracic Surgery: A 10-Year Single-Center Experience
This study retrospectively examines major vascular injuries that occurred during elective thoracic surgeries over a 10-year period at a single tertiary care center.
- Conditions
- Thoracic Surgery, Vascular Injury, Intraoperative Complications
- Trial name
- NCT07100509
- Testing
- Major Vascular Injury During Elective Thoracic Surgery
- Volunteers
- 11 people
- Sponsor
- Caner İşevi, MD
Placenta Accreta, Post Partum Hemorrhage
Conservative Management of Placenta Accreta Spectrum
The resective-constructive surgery, detailed in prior research by Palacios-Jaraquemada JM, involves excising the placenta and its attachment on the myometrium, with modifications including the systematic use of a double JJ probe…
- Conditions
- Placenta Accreta, Post Partum Hemorrhage, Blood Loss Massive
- Trial name
- NCT06253832
- Testing
- conservative surgery for placenta accreta spectrum, hysterectomy
- Where
- Tunisia
- Volunteers
- 36 people
- Sponsor
- Tunis University
Hypotensive Anesthesia, Orthognathic Surgery
Hypotensive Anesthesia for Orthognathic Surgery
The overall objective of this double blinded, randomized controlled trial (RCT) is to compare specific outcomes of three medications (Dexmedetomidine, Nicardipine, and Labetalol) which are routinely used to lower blood pressure…
- Trial name
- NCT06093893
- Testing
- Dexmedetomidine, Nicardipine, Labetalol
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Boston Medical Center
Post Operative Hemorrhage
Intravenous Tranexamic Acid Versus Pericervical Tourniquet To Decrease Blood Loss In Trans-Abdominal Myomectomy
Intravenous Tranexamic Acid Versus Pericervical Tourniquet To Decrease Blood Loss In Trans-Abdominal Myomectomy
- Trial name
- NCT02733952
- Testing
- Tranexamic Acid, Pericervical Tourniquet
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams Maternity Hospital
Nasal Polyps
The Effect of Preoperative Oral Prednisone on the Operative Field During Nasal Polypectomy.
This study aims to determine if a short course of oral prednisone helps to improve the operative field and ease of surgery by minimizing bleeding during nasal polypectomy surgery.
- Trial name
- NCT00440219
- Testing
- Oral Prednisone
- Where
- 2 sites in Canada
- Volunteers
- 34 people
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Blood Loss, Surgical, Postoperative Hemorrhage
Study of the Hemorai Vysio Wearable Device for Monitoring Changes Related to Blood Loss in Patients During and After Surgery.
The goal of this clinical trial is to learn whether the Hemorai Vysio wearable device can be used safely and feasibly to track relative changes over time in tissue oxygen, hemoglobin-related signals, blood flow, and oxygen use…
- Trial name
- VYSIO-FEASIBIL (NCT07826637)
- Testing
- Wearable optical hemodynamic monitoring device
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hemorai Inc
Bleeding
Nasal Desmopressin Versus Oral Bisoprolol for Controlling Bleeding During Endoscopic Sinus Surgery
Functional endoscopic sinus surgery (FESS) is well established for treatment of chronic rhinosinusitis and nasal polyps. Masking of the surgical field can lead to severe complication as tissue injury, increase post-operative…
- Trial name
- NCT05430048
- Testing
- nasal Desmopressin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Zagazig University