Clinical trials: Blood Loss Anemia
Obscure Gastrointestinal Bleeding, Anemia, Iron Deficiency
Depth of Maximal Ileal Insertion During Retrograde Enteroscopy With TTS Balloon
Diagnostic modalities for the evaluation of small bowel pathology include video capsule endoscopy (VCE), antegrade and retrograde device-assisted enteroscopy, CT and MR enterography (1).
- Trial name
- NaviAid2 (NCT04646083)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Thrombotic Microangiopathy, Hemolytic Uremic Syndrome
International Registry and Biorepository for TMA(Thrombotic Microangiopathy)
This registry will collect clinical data and store biosamples (seru, plasma, urine, and DNA) annually from pediatric patients with thrombotic mcroangiopathy
- Conditions
- Thrombotic Microangiopathy, Hemolytic Uremic Syndrome, Thrombotic Thrombocytopenic Purpura
- Trial name
- NCT00593229
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Fetomaternal Hemorrhage, Neonatal Anemia
Identification of Early Predictors of Fetomaternal Hemorrhage
Objectives: 1) To determine risk factors for fetomaternal hemorrhage. 2) To identify a cost-effective method to detect fetomaternal hemorrhage prior to significant fetal anemia.
- Trial name
- NCT01232387
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Aplastic Anemia, Menorrhagia
Treatment of Menorrhagia in Women With Thrombocytopenia Using Platelets or Platelets and Hormones
This study will explore the role of oral contraceptive pills in managing uterine bleeding in women who have low blood platelet counts as a result of aplastic anemia.
- Conditions
- Aplastic Anemia, Menorrhagia, Amenorrhea
- Trial name
- NCT00556400
- Testing
- Lo-Ovral Oral Contraceptive Pills
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Liver Transplantation, Blood Loss
Treatment of Anemia With Intravenous Iron in Patients Listed for Orthotopic Liver Transplantation
The aim of this study is to investigate whether therapy with intravenous iron carboxymaltose in patients with iron deficiency anemia (IDA) listed for orthotopic liver transplantation (OLT) increases hemoglobin concentrations and…
- Trial name
- TRAILER (NCT04475887)
- Testing
- Iron Carboxymaltose
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Immune Thrombocytopenia (ITP), Cold Agglutinin Disease (CAD)
Basket Study to Assess Efficacy, Safety and PK of Iptacopan (LNP023) in Autoimmune Benign Hematological Disorders
The main purpose of this study was to evaluate the efficacy and safety of iptacopan in participants with autoimmune benign hematological disorders such as primary immune thrombocytopenia and primary cold agglutinin disease.
- Trial name
- NCT05086744
- Testing
- Iptacopan
- Where
- 8 sites in United States, Germany and 4 more
- Volunteers
- 19 people
- Sponsor
- Novartis Pharmaceuticals
Obscure Gastrointestinal Bleeding, Iron-Deficiency Anemia
Endoscopic Evaluation for Iron Deficiency Anemia in Patients on Antithrombotic Therapy
This is a single-center, randomized pilot study evaluating the feasibility and safety of two management strategies for patients on antithrombotic therapy who present with obscure gastrointestinal bleeding (OGIB).
- Conditions
- Obscure Gastrointestinal Bleeding, Iron-Deficiency Anemia, Antithrombotic Therapy
- Trial name
- BEACON-IDA (NCT07089030)
- Testing
- Standard endoscopic evaluation, Conservative Medical Management
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Centre intégré universitaire de santé et de services sociaux de la Mauricie-et-du-Centre-du-Québec
Immune Mediated Anemia, Immune Mediated Thrombocytopenia
Using Fostamatinib to Treat Post-Hematopoietic Stem Cell Transplant Immune-mediated Cytopenias
Background: People who have a blood stem cell transplant can sometimes develop cytopenia. This means that their levels of one or more types of blood cell, such as the red cells or platelets, are lower than they should be.
- Conditions
- Immune Mediated Anemia, Immune Mediated Thrombocytopenia, Chronic GVHD
- Trial name
- NCT05502783
- Testing
- fostamatinib
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Anemia, Blood Loss Anemia
Patient Blood Management In CARdiac sUrgical patientS
Nowadays up to 40% of patients undergoing cardiac surgery receives at least 1 unit of red blood cell transfusion during surgery or during the first week after surgery.
- Conditions
- Anemia, Blood Loss Anemia, Iron-deficiency, Iron Deficiency Anemia
- Trial name
- ICARUS (NCT04744181)
- Testing
- Ferric carboxymaltose, B vitamin, Folic acid
- Where
- Italy
- Volunteers
- 479 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Menorrhagia, Dysmenorrhea
Menorrhagia, Dysmenorrhea and Iron Deficiency Among Young Women Soldiers and Effect on Activity
As combat women soldiers are required to more intensive daily activity the investigators believe that the impact of menorrhagia, dysmenorrhea and its clinical consequence (as characterized by, anemia iron deficiency and reduced…
- Conditions
- Menorrhagia, Dysmenorrhea, Iron Deficiency Anemia
- Trial name
- NCT02685501
- Testing
- no intervention
- Where
- 2 sites in Israel
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Bloodloss in Pregnancy
Evaluation of Peripartum Blood Loss and Postpartum Anaemia in Macrosomia & Gemini
Anaemia in pregnant women occurs at a haemoglobin (Hb) concentration <11 g/dL and treatment is essential to prevent increased maternal morbidity, fetal morbidity and mortality.
- Trial name
- NCT06201910
- Testing
- Observation of Blood loss
- Where
- 2 sites in Germany
- Volunteers
- 575 people, healthy volunteers welcome
- Sponsor
- Goethe University
Primary Immune Thrombocytopenia, Warm Autoimmune Hemolytic Anemia
Study of Ianalumab in Adults With Primary Immune Thrombocytopenia (ITP) and Warm-antibody Autoimmune Hemolytic Anemia (wAIHA) Who Have Previously Benefited From Ianalumab
This study is intended to explore the efficacy and safety of a second course of ianalumab after experiencing treatment failure in the pivotal Primary Immune Thrombocytopenia (ITP) trials (CVAY736I12301, CVAY736Q12301) and after…
- Trial name
- VAY RE-HIT (NCT07039422)
- Testing
- Ianalumab
- Sponsor
- Novartis Pharmaceuticals
Upper Gastrointestinal Bleeding
Awareness of Iron Status Evaluation in UGIB
BACKGROUND: Data on the awareness of the need to evaluate iron status and IDA prevalence in acute UGIB are limited. OBJECTIVES: This study aimed to investigate the rate of evaluation of iron status and prevalence of iron…
- Trial name
- AISE (NCT06299007)
- Where
- Thailand
- Volunteers
- 867 people
- Sponsor
- Hat Yai Medical Education Center
Anemia
Menstruation and Anemia Research: A Community Health Study
This research is studying if a community-based, community health worker (CHW) led psychosocial intervention improves hemoglobin levels among Black/African American and/or Hispanic or Latino women with anemia compared to standard…
- Trial name
- MARCH (NCT07832526)
- Testing
- Standard of Care, Informational Series and follow-up support
- Where
- 2 sites in United States
- Volunteers
- 180 people
- Sponsor
- University of Michigan
Anemia
A Study to Observe the Causes and Treatment of Anemia in Critically Ill Children
The purpose of this study is to determine the incidence of anemia and blood transfusions and management of these in critically ill children
- Trial name
- NCT00211055
- Volunteers
- 1,201 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Immune Mediated Anemia, Immune Mediated Thrombocytopenia
Extension Study (Extended Access) of Syk-inhibition Using Fostamatinib to Treat Posttransplant Immune-mediated Cytopenias
Background: People who have a blood stem cell transplant can sometimes develop cytopenia. This means that their levels of one or more types of blood cell, such as the red cells or platelets, are lower than they should be.
- Conditions
- Immune Mediated Anemia, Immune Mediated Thrombocytopenia, Chronic GVHD
- Trial name
- NCT05509582
- Testing
- fostamatinib
- Where
- United States
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Small Bowel Disease, Gastrointestinal Hemorrhage
Bowel Preparation and Prokinetics in Capsule Endoscopy
The aim of this study is to determine whether taking bowel preparation (citramag and senna) or a medicine to speed up transit through the stomach (metoclopramide), will improve the quality of the images seen, increase the transit…
- Conditions
- Small Bowel Disease, Gastrointestinal Hemorrhage, Refractory Anemia
- Trial name
- NCT00275184
- Testing
- Senna, Citramag powder, Metoclopramide
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- London North West Healthcare NHS Trust
Sepsis, Anemia
StatStrip Lactate, Hemoglobin, and Hematocrit Meter in Whole Blood
The purpose of this study is to evaluate the clinical utility of the StatStrip Lactate, Hemoglobin and Hematocrit Hospital Meter System in the testing of whole blood specimens from patients in hospital settings by CLIA waived…
- Conditions
- Sepsis, Anemia, Bleeding, Erythrocytosis
- Trial name
- NCT05118048
- Testing
- Lactate, Hemoglobin, Hematocrit
- Where
- 3 sites in United States
- Volunteers
- 285 people
- Sponsor
- Nova Biomedical
Acute Blood Loss Anemia, Osteoarthritis, Hip
Topical Tranexamic Acid and Acute Blood Loss in Total Hip Arthroplasty
This study aims to assess postoperative blood loss and transfusion rates in total hip replacement after one-time administration of topical tranexamic acid.
- Trial name
- NCT01683955
- Testing
- Tranexamic acid
- Where
- 2 sites in United States
- Volunteers
- 139 people
- Sponsor
- Henry Ford Health System
Benign Prostatic Hyperplasia, Transurethral Resection of the Prostate
Tranexamic Acid for Bleeding Reduction During TURP Surgery
Transurethral resection of the prostate (TURP) is commonly performed in elderly patients and may be associated with perioperative bleeding leading to postoperative anemia and delayed recovery.
- Conditions
- Benign Prostatic Hyperplasia, Transurethral Resection of the Prostate, Perioperative Bleeding, Anemia, Postoperative
- Trial name
- TXA-TURP (NCT07460518)
- Testing
- Tranexamic Acid
- Where
- Morocco
- Volunteers
- 80 people
- Sponsor
- Hamza Najout