Clinical trials: Blood Pressure, Resistant
Obstructive Sleep Apnea Syndrome, Resistant Hypertension
Efficacy of CPAP Treatment on Blood Pressure of Resistant Hypertension Patients With Obstructive Sleep Apnea Syndrome
The aim is to evaluate the effect of treatment with Continuous Positive Airway Pressure (CPAP) device on clinic and ambulatory blood pressures (BP) of 200 resistant hypertensive patients with moderate-severe obstructive sleep…
- Trial name
- NCT01508754
- Testing
- Continuous positive airway pressure treatment
- Where
- Brazil
- Volunteers
- 125 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Dementia, Alzheimer Disease
Effects of Remote-based Resistance Training on Cardiometabolic Risk Factors, Cognitive Function, and Quality of Life in Adults Living With Alzheimer's Disease and/or Related Dementias
The investigators aim to study the effects of a 24-week remote-based resistance exercise training program on cardiovascular disease risk factors, cognitive function, and quality of life in older adults living with mild cognitive…
- Conditions
- Dementia, Alzheimer Disease, Dementia, Vascular, Lewy Body Disease
- Trial name
- NCT05004558
- Testing
- Remote-based Resistance Exercise Training
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Drexel University
Hypertension, Resistant to Conventional Therapy
Addition of Homeopathy in Patients With Resistant Arterial Hypertension
Resistant hypertension (RHTN) is a common clinical problem faced by both primary care clinicians and specialists worldwide. Patients with RHTN have higher rates of cardiovascular events and mortality compared with patients with…
- Trial name
- NCT02124473
- Testing
- Homeopathy
- Where
- 2 sites in India
- Volunteers
- 79 people
- Sponsor
- Macmillan Research Group UK
Diabetes Mellitus Type 2 (T2DM)
Empagliflozin as a Modulator of Systemic Vascular Resistance and Cardiac Output in Patients With Type 2 Diabetes
SGLT2 inhibitors are a novel class of glucose lowering drugs that act in the kidney by inhibiting SGLT2-mediated glucose reabsorption in the proximal tubule.
- Trial name
- EMPA (NCT03132181)
- Testing
- Empagliflozin
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- RWTH Aachen University
Resistant Hypertension, Urinary Incontinence
An Educational Intervention on Medication Adverse Effects in Patients With Resistant Hypertension (HTAR-CSI)
This randomized, single-blind controlled trial evaluates the effectiveness of a nurse-led educational intervention focused on the adverse effects of antihypertensive drugs-specifically sexual dysfunction and urinary…
- Conditions
- Resistant Hypertension, Urinary Incontinence, Sexual Disfunction
- Trial name
- HTAR-CSI (NCT07589881)
- Testing
- Educational Intervention for Adverse Drug Effects, routine care
- Where
- Spain
- Volunteers
- 46 people
- Sponsor
- Consorci Sanitari Integral
Systolic and Diastolic Blood Pressure Levels, Uric Acid Levels
Hyperuricemia on Hypertension and Metabolic Syndrome
The purpose of this study is to evaluate the influence of hyperuricemia treatment compared with placebo on participants with high risk of hypertension and metabolic syndrome.
- Conditions
- Systolic and Diastolic Blood Pressure Levels, Uric Acid Levels, Metabolic Syndrome Parameters, Hepatic Enzymes
- Trial name
- NCT01157936
- Testing
- Allopurinol
- Where
- Mexico
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
Cardiovascular Diseases
Effect of Exercise or Metformin on Nocturnal Blood Pressure and Other Risk Factors for CVD Among Obese Adolescents
The objective is to, among obese adolescents, study impact of regular physical activity or metformin therapy on nocturnal blood pressure and related cardiovascular disease risk factors.
- Trial name
- NCT00889876
- Testing
- Metformin group, Exercise
- Where
- Sweden
- Volunteers
- 26 people
- Sponsor
- Maria Sandberg Westerstahl
Metabolic Syndrome, Menopause
Effects of L-citrulline Supplementation on Vascular Function in Metabolic Syndrome
The objective of this project is to provide evidence that L-Citrulline (CIT) supplementation can improve vascular function in the fasted and acute hyperglycemia conditions in middle-aged and older women with metabolic syndrome.
- Trial name
- NCT06025357
- Testing
- L-Citrulline supplementation
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Obesity, Chronic Kidney Disease
FFT, Inflammation, Lipid Metabolism, Blood Pressure and Organ Damage in Patients With Obesity, Chronic Kidney Disease (CKD).
Fructose intake from added sugars has increased dramatically over the last century and has recently been implicated as potential contributor to metabolic syndrome, obesity, hypertension, inflammation and kidney disease.
- Conditions
- Obesity, Chronic Kidney Disease, Metabolic Syndrome
- Trial name
- NCT01332526
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Collegium Medicum w Bydgoszczy
Blood Pressure Management, Blood Pressure Monitoring, Ambulatory
Impact of Resistance Training Intensity on Blood Pressure
The goal of the clinical trial is to understand the effect of two resistance training protocols employing different loading intensities (% of 1 repetition maximum; 1-RM), but with standardized effort intensity (2 repetitions in…
- Conditions
- Blood Pressure Management, Blood Pressure Monitoring, Ambulatory, Blood Pressure, High, Blood Pressure
- Trial name
- HEART (NCT06845514)
- Testing
- Condition LL-RE, Control, Condition HL-RE
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Hypertension
A Multicenter Study to Evaluate the ROX Anastomotic Coupler System (ACS) In Patients With Severe Hypertension
The purpose of this study is to evaluate the safety and performance of the ROX Anastomotic Coupler System (ACS) in patients with severe hypertension.
- Trial name
- NCT01682057
- Testing
- ROX ANASTOMOTIC COUPLER SYSTEM (ACS)
- Where
- Belgium
- Volunteers
- 8 people
- Sponsor
- ROX Medical, Inc.
Metabolic Syndrome
NWT03 and Arterial Stiffness
Rationale: Subjects with the metabolic syndrome have an increased risk of developing cardiovascular disease and a twofold risk of developing hypertension.
- Trial name
- NCT02561663
- Testing
- NWT-03, an egg-white protein hydrolysate
- Where
- Netherlands
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Newtricious R&D BV
Metabolic Syndrome, Triglycerides
Therapeutic Lifestyle Modifications to Reduce Burden of Chronic Disease
The investigators previously established that there was a high burden of disease among all categories of staff at the University of the West Indies, St.
- Conditions
- Metabolic Syndrome, Triglycerides, Blood Pressure, Diabetes
- Trial name
- NCT01277614
- Testing
- Therapeutic lifestyle
- Where
- Trinidad and Tobago
- Volunteers
- 144 people
- Sponsor
- The University of The West Indies
Cardiovascular Diseases, Hypertension
Insulin Resistance and Blood Pressure Regulation in Blacks
To determine the role of insulin resistance in peripheral vascular dynamics, sodium sensitivity, and blood pressure regulation in a young representative Black population and in a group of young Blacks at high risk for…
- Conditions
- Cardiovascular Diseases, Hypertension, Heart Diseases, Insulin Resistance
- Trial name
- NCT00005164
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Health-Related Physical Fitness
Effects of Microdosed Resistance Training During Physical Education on Health-Related Fitness in Adolescents
This study will examine whether short bouts of resistance training incorporated into physical education lessons can improve health-related physical fitness in secondary school students aged 15-16 years.
- Trial name
- NCT07845864
- Testing
- Resistance training microdosing during physical education
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Wroclaw University of Health and Sport Sciences
Obesity, Insulin Resistance
Metabolic Effects of Angiotensin-(1-7)
The overall purpose of this study is to learn more about the metabolic effects of angiotensin-(1-7) in the insulin resistant state associated with obesity.
- Conditions
- Obesity, Insulin Resistance, Hypertension, Metabolic Cardiovascular Syndrome
- Trial name
- NCT02646475
- Testing
- Angiotensin-(1-7), Saline
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Vanderbilt University
Metabolic Syndrome (MetS), Hypertension (HTN)
Metabolic Surgery for Metabolic Syndrome
This study is designed to understand how bariatric surgery affects patients with metabolic syndrome over both the short and long term.
- Conditions
- Metabolic Syndrome (MetS), Hypertension (HTN), Obesity, T2
- Trial name
- NCT07183137
- Where
- 3 sites in China
- Volunteers
- 1,581 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Resistant Hypertension, Secondary Hypertension
Comparison of Catecholamine Concentrations in Venous Blood During Selective Adrenal Artery Embolization
To explore the relationship between perioperative blood pressure and catecholamine concentrations in adrenal venous blood and peripheral venous blood in hypertensive patients with primary aldosteronism (PA) who underwent…
- Conditions
- Resistant Hypertension, Secondary Hypertension, Secondary Hypertension to Endocrine Disorders, Primary Aldosteronism
- Trial name
- NCT06228677
- Testing
- Selective adrenal artery embolization
- Where
- China
- Volunteers
- 196 people
- Sponsor
- First Affiliated Hospital of Chengdu Medical College
Preeclampsia
A Study of Cerebral-circulatory Response to Intravenous Antihypertensive Treatment in Women With Serious Preeclampsia
The purpose of this study is a systematical registration of hemodynamic measurements (cardiac output, blood pressure and systemic vascular resistance) in women with serious preeclampsia.
- Trial name
- NCT00403572
- Volunteers
- 8 people
- Sponsor
- Oslo University Hospital
Treatment Resistant Hypertension, Chronic Hemodialysis
Effect of Renal Denervation on Bood Pressure in Patients on Hemodialysis
The RDN-HD Study is a prospective, single-center feasibility study. All patients included will undergo endovascular ultrasound-based RDN (no sham group, no blinding).
- Trial name
- RDN-HD (NCT06556407)
- Testing
- renal denervation
- Where
- Germany
- Volunteers
- 12 people
- Sponsor
- University of Erlangen-Nürnberg Medical School