Clinical trials: Blood Pressure, completed
Essential Hypertension
Olmesartan Medoxomil Versus Losartan in Elderly and Very Elderly
To assess the efficacy of individually optimized doses of olmesartan medoxomil compared to losartan in elderly and very elderly patients with essential hypertension.
- Trial name
- NCT00751751
- Testing
- olmesartan medoxomil + hydrochlorothiazide, if necessary, losartan + hydrochlorothiazide, if necessary
- Where
- Germany
- Volunteers
- 441 people
- Sponsor
- Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company
Elevated Blood Pressure, Hypertension
Groceries for Black Residents of Boston to Stop Hypertension Among Adults Without Treated Hypertension
GoFresh is a randomized trial, testing the effects of a home-delivered DASH-patterned grocery intervention on blood pressure in Black adults, residing in Boston area urban food deserts.
- Trial name
- GoFresh (NCT05121337)
- Testing
- Dietitian-Assisted DASH groceries, Self-directed shopping
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Beth Israel Deaconess Medical Center
Hypertension, Diabetes Mellitus
Diabetes Risk Evaluation and Management Tele-monitoring Study (DREAM-Tel)
The purpose behind the proposed research is that diabetes care in First Nations people can be improved by involvement of a Home Care team providing diabetes education and management, supported by emerging technology, specifically…
- Trial name
- DREAM-Tel (NCT00325624)
- Testing
- Bluetooth-enabled Glucometer
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- Sunnybrook Health Sciences Centre
Hypertension, Cardiovascular Diseases
Effect of Aerobic Exercise on Blood Pressure Changes
This study will evaluate the effect of an aerobic training program versus a strength training program on the autonomic nervous system at rest and in response to challenge.
- Trial name
- NCT00358137
- Testing
- Aerobic Conditioning Program, Strength Training Program
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Hypertension
Improving Hypertension Control in East and Central Harlem
This hypertension project is evaluating strategies developed to target problems underlying lack of blood pressure control among treated but uncontrolled hypertensive patients in East and Central Harlem.
- Trial name
- NCT00211666
- Testing
- Nurse management, home blood pressure monitors, and a chronic disease self management course.
- Where
- United States
- Volunteers
- 480 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Spinal Cord Injury
Transcutaneous Stimulation in Spinal Cord Injury
Cardiovascular disease has become the leading cause of death in the spinal cord injury population. Increased reliance on the renin-angiotensin-aldosterone system (RAAS) is believed to decrease falls in blood pressure when moving…
- Trial name
- SCI (NCT05180227)
- Testing
- DS8R
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- VA Office of Research and Development
Hypertension
A Study of the Effects of 6R-BH4 on Blood Pressure in Subjects With Poorly Controlled Systemic Hypertension
The purpose of this study is to determine whether 6R-BH4 (sapropterin dihydrochloride) is safe and effective in the treatment of poorly controlled hypertension in the presence or absence of type 2 diabetes.
- Trial name
- NCT00325962
- Testing
- 6R-BH4 (sapropterin dihydrochloride)
- Where
- 24 sites in United States
- Volunteers
- 84 people
- Sponsor
- BioMarin Pharmaceutical
Primary Hypertension
The Effectiveness of "MaRiTensi" in Increasing Self-Care and Blood Pressure Control: Randomized Controlled Trial
This study aims to know the effectiveness of "MaRiTensi" in improving knowledge, motivation, efficacy, self-care and blood pressure control for hypertension patients.
- Trial name
- "MaRiTensi" (NCT06049862)
- Testing
- MaRiTensi App
- Where
- 3 sites in Indonesia
- Volunteers
- 99 people
- Sponsor
- Chatarina Setya Widyastuti
Hypertension
Assessment of Efficacy and Safety of Olmesartan Medoxomil in Children and Adolescent Patients With High Blood Pressure
This study assesses the efficacy and safety of olmesartan medoxomil in children ages 1-16 with high blood pressure. After a 5-week blinded treatment period of up to 5 weeks participants can continue to take olmesartan medoxomil…
- Trial name
- NCT00151775
- Testing
- olmesartan medoxomil
- Where
- 65 sites in United States, Argentina and 9 more
- Volunteers
- 362 people
- Sponsor
- Daiichi Sankyo
Vascular Function
Flow Mediated Dilation in Response to Black Tea
Research indicate that people who regularly drink tea have a reduced risk of stroke or heart disease. In a number of studies in which people that normally do not drink showed that their blood vessels function improved when the…
- Trial name
- T (NCT02273323)
- Testing
- Tea
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Unilever R&D
Resistance Exercise Pressor and Neural Responses in Older Women
Blood Pressure Reactivity After Resistance Exercise in Older Women
The purpose of this study is to determine and compare the effects of two sessions of resistance exercise in blood pressure reactivity to a mental stress test in older hypertensive women.
- Trial name
- NCT03002714
- Testing
- Exercise
- Volunteers
- 10 people
- Sponsor
- University of Brasilia
General Anesthesia
Effect of Dobutamine on Hepatic Blood Flow During Goal-directed Hemodynamic Therapy
Maintaining adequate perfusion pressure and oxygen supply is essential for organ survival. Splanchnic hypoperfusion during the perioperative period in abdominal surgery may result in mucosal ischemia with increased permeability…
- Trial name
- DOBU whipple (NCT04893655)
- Testing
- Dobutamine Hydrochloride
- Where
- Belgium
- Volunteers
- 58 people
- Sponsor
- University Hospital, Ghent
Normotensive, Obstructive Sleep Apnea
Normotensive OSA Patients With Nondipper Circadian Blood Pressure Pattern
The principal objective is to evaluate the effect of CPAP treatment on blood pressure (BP) in normotensive patients with nondipper circadian pattern with sleep apnea-hypopnea syndrome (SAHS).
- Trial name
- Nondipper-OSA (NCT03987425)
- Testing
- CPAP treatment
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Hypertension,Essential
Licorice and Home Blood Pressure
Out-of-office blood pressure is more strongly associated with cardiovascular risk than office blood pressure. Licorice is known to raise blood pressure, but no previous studies have measured the effects on home blood pressure.
- Trial name
- NCT05661721
- Testing
- Sweet licorice, Salty licorice
- Where
- Sweden
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Hypertension, Aging
Effects of Lifestyle Walking on Blood Pressure in Older Adults With Hypertension
Eight out of ten older adults have hypertension in the US, which is a strong risk factor for cardiovascular events. To manage hypertension, regular and structured exercise is effective and strongly recommended regardless of drug…
- Trial name
- NCT05433233
- Testing
- Walking, HAPA Behavior Change Counseling
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Iowa State University
Metabolic Syndrome, Elevated Blood Pressure
Evaluation of a Nigella Sativa Extract (10% Thymoquinone, Nisatol®) in Perimenopausal Women With Metabolic Syndrome
A prospective, multicenter, randomized controlled study evaluating the efficacy and safety of a Nigella sativa extract standardized to 10% thymoquinone (Nisatol®) in perimenopausal women with metabolic syndrome.
- Trial name
- NCT07013058
- Testing
- Nigella sativa extract (Nisatol®), Mediterranean Diet
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Metabolic Syndrome
Effect of Fish Oil on Markers of the Metabolic Syndrome in Overweight Adolescent Boys
The aim of the study is to investigate if dietary fish oil has a beneficial effect on blood pressure, insulin sensitivity, blood lipid profile, body composition and metabolic rate in healthy, but slightly overweight, teenage…
- Trial name
- TeenFisk (NCT00929552)
- Testing
- Dietary oils (fish, vegetable oil)
- Where
- Denmark
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Spinal Cord Injury
Orthostatic Tolerance During FES (Functional Electrical Stimulation)-Walking in Paraplegia
Objective: The objective of this research is to undertake a safety and viability study of FES-evoked stepping in individuals with paraplegia.
- Trial name
- NCT00108043
- Testing
- FES-evoked functional upright gait
- Where
- Australia
- Volunteers
- 10 people
- Sponsor
- University of Sydney
Obesity, Diabetes
Effect of a Treatment of Lifestyle Changes on the Prevalence of Metabolic Syndrome and Body Weight in Mexican Women
The metabolic syndrome is a group of cardiometabolic risk factors that reflect a sedentary lifestyle and the excessive intake of food among the risk factors that comprise it are located the obesity, hyperglycemia, dyslipidemia…
- Conditions
- Obesity, Diabetes, High Blood Pressure, Dyslipidemia
- Trial name
- MPATPCDNC (NCT02247635)
- Testing
- Healthy lifestyle and adherence
- Where
- Mexico
- Volunteers
- 180 people
- Sponsor
- Mexican National Institute of Public Health
Type 2 Diabetes
Time Course of the Blood Pressure Lowering Effect of Liraglutide Therapy in Type 2 Diabetes
Background: Preclinical blood pressure (BP) data from studies of hypoglycemic effects of liraglutide treatment (the LEAD program), revealed a significant antihypertensive potential.
- Trial name
- Liratime (NCT01499108)
- Testing
- liraglutide
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- Peter Rossing
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