Clinical trials: Blood Pressure, completed
Diabetes, Cardiovascular Disease
Relationship of Central Blood Pressure and Pulse Wave Velocity With Target Organ Damage
Diabetic patients show an increased prevalence of non dipping arterial pressure pattern, target organ damage and elevated arterial stiffness. These alterations are associated with increased cardiovascular risk.
- Trial name
- LOD-DIABETES (NCT01065155)
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Fundacion para la Investigacion y Formacion en Ciencias de la Salud
Diabetes, Chronic Disease
NC Works4Health: Reducing Chronic Disease Risks in Socioeconomically Disadvantaged, Unemployed Populations
The proposed study, NC Works4Health (NCW4H), builds on the strengths of long-standing academic-community research partnerships between this UNC at Chapel Hill (UNC) team of investigators and key stakeholders across health, social…
- Conditions
- Diabetes, Chronic Disease, Psychological Distress
- Trial name
- NCW4H (NCT04815278)
- Testing
- Immediate Chronic Disease Prevention Program (CDPP), Workplace Equity, Job and Health Supports Employer Intervention, Delayed, attenuated Chronic Disease Prevention Program (CDPP)
- Where
- United States
- Volunteers
- 455 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Diabetes Mellitus
Study of Raisins Versus Alternative Snacks in Patients With Type 2 Diabetes Mellitus
The objective of this study is to compare the effects of Raisins three times per day versus alternative snacks three times per day on blood sugar control and cardiovascular risk factors (weight, waist circumference, blood…
- Trial name
- NCT01677936
- Testing
- Raisins, Snacks
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Louisville Metabolic and Atherosclerosis Research Center
Arterial Hypertension, Vitamin D Deficiency
Styrian Vitamin D Hypertension Trial
In this randomized, double-blind, placebo-controlled trial we plan to enrol 200 vitamin D deficient hypertensive patients. Our main objective is to evaluate whether vitamin D3 supplementation with 2,800 IU daily for 8 weeks has…
- Trial name
- NCT02136771
- Testing
- Vitamin D3
- Where
- Austria
- Volunteers
- 200 people
- Sponsor
- Medical University of Graz
Hypertension
ENCORE: Exercise and Nutritional Interventions for Cardiovascular Health
This study is an NIH-funded clinical trial conducted at Duke Medical Center evaluating the effects of the DASH diet alone and combined with a behavioral weight loss program on blood pressure and various vascular measures.
- Trial name
- ENCORE (NCT00571844)
- Testing
- DASH diet, DASH diet plus Weight loss
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Duke University
Hypertension
The Role of Aldosterone on Augmented Exercise Pressor Reflex in Hypertension
Hypertensive patients often show an exaggerated rise in blood pressure during exercise through overactivity of the exercise pressor reflex.
- Trial name
- NCT01996449
- Testing
- Eplerenone, Amlodipine, Microneurography
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Anaemia
Anemia Study in Chronic Kidney Disease (CKD): Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat-Blood Pressure (ASCEND-BP)
This will be an open-label, randomized, parallel-group study in hemodialysis-dependent (HD) participants with anemia associated with chronic kidney disease (CKD), designed to compare the effects of daprodustat to epoetin alfa on…
- Trial name
- NCT03029247
- Testing
- Daprodustat, Epoetin alfa
- Where
- 11 sites in United States
- Volunteers
- 105 people
- Sponsor
- GlaxoSmithKline
Ocular Physiology, Microcirculation
Role of Adenosine in the Control of Choroidal Blood Flow During Changes in Ocular Perfusion Pressure.
Autoregulation is the ability of a vascular bed to maintain blood flow despite changes in perfusion pressure. For a long time it had been assumed that the choroid is a strictly passive vascular bed, which shows no autoregulation.
- Trial name
- NCT00712764
- Testing
- Adenosine
- Where
- Austria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Diabetes, High Blood Pressure
Study Title: Food Rx
Researchers are trying to determine if subjects with lack of access to healthy food and a long term health problem, are helped by a weekly box of healthy groceries and nutrition education.
- Conditions
- Diabetes, High Blood Pressure, Obesity, Hypertension
- Trial name
- NCT03937934
- Testing
- Nutrition Education
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Mayo Clinic
Blood Pressure, Obesity
Blood Pressure Changes After Bariatric Surgery
The aim of the study is to assess changes in blood pressure, cardiac function and selected laboratory measurements after bariatric surgery and to find most important factors associated with blood pressure reduction after weight…
- Conditions
- Blood Pressure, Obesity, Bariatric Surgery, Hypertension
- Trial name
- NCT06460233
- Testing
- Bariatric surgery - sleeve gastrectomy
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Warsaw
Hypertension, Metabolic Disorder
A 52 Week Study to Evaluate the Effects of Losartan With or Without HCTZ on Plasma Glucose, Metabolic Parameters, Blood Pressure in Hypertensive Patients With Metabolic Syndrome (0954A-331)
To determine if a one year treatment Losartan with or without HCTZ at different dosages have an effect on metabolic parameters in patients with hypertension and the metabolic syndrome.
- Trial name
- NCT00546052
- Testing
- losartan potassium (+) hydrochlorothiazide
- Volunteers
- 1,738 people
- Sponsor
- Organon and Co
Circadian Rhythm, Blood Pressure
Circadian Mechanisms Underlying Non-Dipping Blood Pressure in Blacks
This study seeks to examine central and peripheral circadian mechanisms in Blacks with appropriately dipping systolic blood pressure (blood pressure that dips by at least 10%) compared with non-dipping systolic blood pressure…
- Trial name
- NCT03934255
- Testing
- Constant Routine Protocol
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Healthy, Hypertension
Validation of Noninvasive Blood Pressure Device
This is a prospective, nonrandomized multi-center study for the investigation of noninvasive sphygmomanometers. The purpose of the study is to validate the clinical performance of the Masimo noninvasive blood pressure device…
- Conditions
- Healthy, Hypertension, Hypotension
- Trial name
- NCT04676152
- Testing
- Masimo Noninvasive Blood Pressure Device
- Where
- 2 sites in United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Hypertension, Cardiovascular Disease
Effects of Nitrate in Vegetables on Blood Pressure in Subjects With Prehypertension
The purpose of this study is to examine the effect of different vegetables on cardiovascular function in subjects with moderately increased blood pressure.
- Trial name
- DINO (NCT02916615)
- Testing
- High nitrate vegetables, Low nitrate vegetables + nitrate, Low nitrate vegetables
- Where
- Sweden
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Hypoxia, Altitude
Effects of Nebivolol Versus Carvedilol on Cardiopulmonary Function at High Altitude in Healthy Subjects.
Exposure of healthy subjects to high altitude hypoxia elicits changes in cardiovascular, respiratory and metabolic features as weel as in exercise performance similar, for some aspects, to those observed in chronic heart failure.
- Conditions
- Hypoxia, Altitude, Heart Failure
- Trial name
- NCT00924833
- Testing
- Carvedilol, Nebivolol
- Where
- Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Prehypertension
When the Kidney Reacts to Nutritional Changes
Hypertension is one of the leading causes of morbidity and mortality in the industrialized world, attributed mostly to modifiable lifestyle factors.
- Trial name
- NCT04142138
- Testing
- DASH
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Rockefeller University
Blood Pressure, Coronary Artery Disease
Ambulatory Blood Pressure Monitoring in Patients With Coronary Artery Disease
Background: Office blood pressure (OBP) is used for diagnosing and treating hypertension but ambulatory blood pressure measurement (ABPM) associates more accurately with patient outcome.
- Conditions
- Blood Pressure, Coronary Artery Disease, Hypertension
- Trial name
- PCI-BP (NCT04649463)
- Testing
- Open ABPM results
- Volunteers
- 200 people
- Sponsor
- Karolinska Institutet
Thoracic Surgical Procedures, One-lung Ventilation (OLV)
Study of Cardiac Power Index During Supine, Lateral, and Between Left and Right Positions During Two- and One-Lung Ventilation (OLV): Comparison of Hemodynamic Changes After Lung Recruitment Maneuver and Fluid Challenge Among Responders and Non-Responders (SVI, MAP, CPI Changes).
The aim of this trial is to study the changes of the Cardiac Power Index (CPI) during supine and lateral decubitus position in two and one lung ventilation respectively.
- Conditions
- Thoracic Surgical Procedures, One-lung Ventilation (OLV), Hemodynamic Changes
- Trial name
- NCT07037225
- Testing
- Fluid challenge during one-lung ventilation (OLV) in the lateral decubitus position, Hemodynamic monitoring
- Where
- Greece
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Maria Fountoulaki
Vegetables, Cardiovascular Disease
Clinical Investigation on the Effects of a Vegetable Juice Treatment
The purpose of the investigators study is to investigate the impact of a commercial vegetable juice on dietary vegetable intake and select cardiovascular risk factors in a generally healthy population.
- Conditions
- Vegetables, Cardiovascular Disease, Blood Pressure
- Trial name
- NCT01161706
- Testing
- Vegetable Juice
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Hypercholesterolemia
Replacement of Saturated Fat in Dairy on Total Cholesterol
The consumption of milk and dairy products is recognised as an essential part of a healthy diet as it represents an important source of key micro- and macronutrients.
- Trial name
- RESET (NCT02089035)
- Testing
- MUFA-rich dairy products (UHT milk, cheese and butter), Conventional dairy products (UHT milk, cheese, butter)
- Where
- United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Reading
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