Clinical trials: Blood Pressure, completed
Hemodynamic, Exercise
Sex and Exercise-mode Differences in Post Exercise Blood Pressure and Heart Rate Variability Responses During Workday
The present study compared the acute effects of Sex and exercise mode on subsequent blood pressure (BP) and heart rate variability (HRV) responses during daily work in healthy adults.
- Trial name
- NCT03080636
- Testing
- Aerobic exercise, Resistance exercise, Control session
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of Uberlandia
Hypertension
Efficacy and Safety of Aliskiren and Atenolol in Adults (>18) With Mild to Moderate Hypertension
This is a study for people diagnosed with hypertension to compare the safety and effectiveness of aliskiren alone and in combination with atenolol. Each patient will be in the study for 12 weeks.
- Trial name
- NCT00262236
- Testing
- Aliskiren
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 693 people
- Sponsor
- Novartis
Renal Artery Obstruction, Stents
Compare Effects of Intensive Versus Conventional Lipid-lowering Therapy in Patients With Severe Atherosclerotic Renal Artery Stenosis Undergoing Stent Placement
Although expert consensuses recommend the use of statins in the treatment of atherosclerotic renal artery stenosis, in patients with severe atherosclerotic renal artery stenosis undergoing stent placement, the related…
- Conditions
- Renal Artery Obstruction, Stents, Lipids, Glomerular Filtration Rate
- Trial name
- NCT03521700
- Testing
- Rosuvastatin
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Suspected Arterial Hypertension
Central Blood Pressure Over 24 Hours (ABPM) and Left Ventricular Mass
The investigators aim to investigate whether central systolic blood pressure, as measured during regular 24 hour ambulatory blood pressure monitoring (ABPM), is a better predictor of left ventricular mass than peripheral systolic…
- Trial name
- NCT01278732
- Testing
- no intervention performed
- Where
- 10 sites in Austria, Germany and 5 more
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Klinikum Wels-Grieskirchen
Hypertension
Zilebesiran as Add-on Therapy in Patients With Hypertension Not Adequately Controlled by a Standard of Care Antihypertensive Medication (KARDIA-2)
The purpose of this study is to evaluate the effect of zilebesiran on systolic and diastolic blood pressure and to characterize the pharmacodynamic (PD) effects and safety of zilebesiran as add-on therapy.
- Trial name
- KARDIA-2 (NCT05103332)
- Testing
- Indapamide, Amlodipine, Olmesartan
- Where
- 110 sites in United States, Canada and 6 more
- Volunteers
- 663 people
- Sponsor
- Alnylam Pharmaceuticals
Hypertension
Dietary Counseling or Potassium Supplement to Increase Potassium Intake in Patients With High Blood Pressure
High blood pressure is the leading cause of cardiovascular disease worldwide. Many medicines are available to lower blood pressures successfully, as well as many non-medical options, such as dietary changes.
- Trial name
- NCT03809884
- Testing
- Dietary Counselling, Potassium Citrate
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- Ottawa Hospital Research Institute
Blood Pressure, Intraoperative Hypotension
Perioperative Personalized Blood Pressure Management: IMPROVE-multi
Rates of major complications and mortality in the first weeks after surgery remain very high: postoperative mortality is still around 2% in central Europe and the United States.
- Conditions
- Blood Pressure, Intraoperative Hypotension, Postoperative Complications, Surgery
- Trial name
- IMPROVE (NCT05416944)
- Testing
- Personalized blood pressure management
- Where
- Germany
- Volunteers
- 1,272 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Pulmonary Hypertension
Evaluation of the Pharmacodynamic Effect of the Combination of Sildenafil and Riociguat on Blood Pressure and Other Safety Parameters.
Pulmonary Arterial Hypertension (PAH) is a severe progressive disease with a high mortality. Although several drugs are available for the treatment of PAH none offer a cure, therefore there is still a high medical need for new…
- Trial name
- PATENT PLUS (NCT01179334)
- Testing
- Riociguat (Adempas, BAY63-2521), Sildenafil
- Where
- 25 sites in United States, Austria and 7 more
- Volunteers
- 18 people
- Sponsor
- Bayer
Cardiac Diseases
Ultrapower; a Minimally Invasive Tool for Evaluation of Total Cardiac Power
The heart is essentially a hydraulic pump which ensures adequate delivery of blood through generating pressure and forward flow of blood.
- Trial name
- NCT02727634
- Testing
- Comparison cardiac power and cardiac power output at different time points in the perioperative period
- Where
- Norway
- Volunteers
- 28 people
- Sponsor
- Norwegian University of Science and Technology
Subarachnoid Hemorrhage, Intracerebral Hemorrhage
Safety and Efficacy of Nicardipine for the Control of Blood Pressure After SAH
The purpose of this research is to explore ways to improve and simplify control of blood pressure in patients with SAH or ICH. This research will be done by comparing tow different medications that are routinely used to help…
- Trial name
- NCT00490464
- Testing
- Nicardipine and Nipride
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- University of Illinois Chicago
Hypertension
BEtter Control of Blood Pressure in Hypertensive pAtients Monitored Using the HOTMAN® sYstem
The purpose of this study is to demonstrate that monitoring hemodynamic parameters and then applying a predefined algorithm of drug selection (i.e.
- Trial name
- BEAUTY (NCT01482364)
- Testing
- Integrated hemodynamic management (IHM) - HOTMAN System, Non Integrated Hemodynamic Management (Non-IHM) - HOTMAN System
- Where
- 5 sites in Estonia, France and 3 more
- Volunteers
- 183 people
- Sponsor
- Hemo Sapiens, Inc.
Essential Hypertension
Olmesartan in Essential Hypertension
To test the efficacy and safety of olmesartan in patients with essential hypertension.
- Trial name
- NCT00185172
- Testing
- olmesartan medoxomil, olmesartan medoxomil oral tablets, hydrochlorothiazide oral tablets
- Where
- 8 sites in Austria, Germany and 6 more
- Volunteers
- 2,333 people
- Sponsor
- Sankyo Pharma Gmbh
Hypertension
Treatment of Pediatric Hypertension With Altace Trial
Ramipril is an ACE inhibitor that has been marketed in the US for the treatment of hypertension since 1991. It has been shown to be effective in reducing both systolic and diastolic blood pressure in adults when used once daily.
- Trial name
- NCT00044265
- Testing
- ramipril
- Where
- 30 sites in United States
- Volunteers
- 310 people
- Sponsor
- Pfizer
Health, Blood Pressure
The Effect of Purple Sweet Potato (PSP)-Juice on Liver Enzymes and Blood Pressure
Purple Sweet Potato juice (PSP-juice) is a juice based on purple-fleshed sweet potato concentrate, containing a high level of anthocyanins.
- Conditions
- Health, Blood Pressure, Liver Function, Insulin Resistance
- Trial name
- NCT00962195
- Testing
- purple sweet potato (PSP)-juice
- Where
- Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- TNO
Hypertension
Improving Adherence to Blood Pressure Guidelines
The purpose of this study is to evaluate the impact of physician/pharmacist collaborative teams on hypertension guideline adherence for patients with uncontrolled hypertension in six family medicine practice sites in Iowa.
- Trial name
- NCT00201019
- Testing
- Physician-pharmacist collaborative intervention
- Where
- United States
- Volunteers
- 623 people
- Sponsor
- University of Iowa
Chronic Kidney Disease, Diabetes Mellitus, Type 2
GLUcose Transport and REnalPROtection in Chronic Kidney Disease
This is a single-center, double blind, randomized, parallel-arms study designed to investigate the effects of a six-month treatment with the SGLT2i dapagliflozin on markers of kidney senescence, inflammation and…
- Conditions
- Chronic Kidney Disease, Diabetes Mellitus, Type 2, Hypertension
- Trial name
- GLUTREPRO (NCT05998837)
- Testing
- Dapagliflozin 10mg Tab
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
Eye Movement Desensitization and Reprocessing Intervention, Blood Pressure
The Effect of Eye Movement Desensitization and Reprocessing Intervention in Hypertension Patient.
Eye Movement Desensitization and Reprocessing intervention may improve anxiety, depression, systolic blood pressure and heart rate variability in patients with hypertension.
- Conditions
- Eye Movement Desensitization and Reprocessing Intervention, Blood Pressure, Heart Rate Variability, Anxiety
- Trial name
- EMDR (NCT05836181)
- Testing
- Eye Movement Desensitization and Reprocessing
- Where
- Taiwan
- Volunteers
- 110 people
- Sponsor
- Miao-Yi Chen
Coronavirus Infections
Covid-19 Triage Using Camera-based AI
The vital signs are critical in assessing the severity and prognosis of infections, such as Covid-19. The devices used today for measuring the vital signs have to be in physical contact with the patients.
- Trial name
- NCT04383457
- Testing
- RIA-device (Remote Investigation and Assessment)
- Where
- Sweden
- Volunteers
- 214 people
- Sponsor
- Vastra Gotaland Region
Health Effects of Aronia
Potential Health Effects of Aronia Intake
Intervention cross-over study during which participants receive standardized amounts of aronia berry tablets or placebo for three months, then wash out for three months, then aronia tablets or placebo for three months.
- Trial name
- NCT03405753
- Where
- Denmark
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Cardiovascular Diseases
Impact of Hibiscus on Cardiovascular Disease Risk
Hibiscus sabdariffa calyces (HSC) extract is consumed in different parts of the world as a cold or hot drink and is available in the United Kingdom (UK) markets in different forms including tea bags.
- Trial name
- PHYTOVAS (NCT02165553)
- Testing
- Hibiscus sabdariffa calyces extract as a cold drink
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Reading
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