Clinical trials: Blood Pressure, completed
Hypertension
Controlling Blood Pressure in Treatment Resistant Hypertension: A Pilot Study
Comparative Effectiveness Research using an intent-to-treat approach in 8 clinics in South Carolina. The investigators will assess 4 efficacious approaches to controlling treatment-resistant hypertension (TRH): Aldosterone…
- Trial name
- TRH (NCT02167464)
- Testing
- Renin treatment-guided Therapeutics, Referral Hypertension specialist, Aldosterone Antagonist
- Where
- 8 sites in United States
- Volunteers
- 70 people
- Sponsor
- Medical University of South Carolina
Hypertension
Accuracy Testing of Validated and Non-validated Home BP Devices Sold on the Online Market.
This study aims to assess whether validated and non-validated blood pressure measuring devices sold on the online market are accurate in regards to the mean awake BP from ambulatory blood pressure monitoring.
- Trial name
- VALID-HomeBP (NCT06688409)
- Testing
- awake ABPM
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Blood Pressure, Arrhythmia
Effects of Fatty and Lean Fish Intake on Cardiovascular Risk Factors in Subjects With Coronary Heart Disease
The aim of the study is to examine the effects of fatty fish and white (lean) fish on cardiovascular disease risk factor levels in subjects with established coronary heart disease using multiple medications.
- Conditions
- Blood Pressure, Arrhythmia, Inflammation
- Trial name
- NCT00720655
- Testing
- Dietary intervention
- Where
- Finland
- Volunteers
- 33 people
- Sponsor
- University of Eastern Finland
Shock; Septic, Critical Illness
Targeted Tissue Perfusion Versus Macrocirculatory-guided Standard Care in Patients With Septic Shock
Background: The recommended monitoring and target levels in septic shock (SSC Guidelines 2012) including mean arterial pressure (MAP) target are not based on robust clinical data.
- Trial name
- TARTARE-2S (NCT02579525)
- Testing
- Hemodynamical treatment TTP, Hemodynamical treatment MCG
- Where
- 2 sites in Finland, Switzerland
- Volunteers
- 200 people
- Sponsor
- Helsinki University Central Hospital
Coronary Artery Disease., Aortic Valve Stenosis.
Cerebral Oxymetry at Elective Coronary and Valve Surgery.
Use of vasopressor to maintain Mean Arterial Pressure on Cardio Pulmonary Bypass can lead to decreased cerebral flow and oxygenation in individual patients and this can be detected by means of cerebral oxymetry.
- Conditions
- Coronary Artery Disease., Aortic Valve Stenosis., Aortic Valve Regurgitation.
- Trial name
- Co-HLM (NCT01940874)
- Where
- Norway
- Volunteers
- 54 people
- Sponsor
- Oslo University Hospital
Stroke, Acute, Blood Pressure
Central and Peripheral Blood Pressure in Stroke
Individuals who experience a stroke or transient ischaemic attack (TIA) are at heightened risk of subsequent vascular events, including heart attacks and secondary stroke/TIA.
- Trial name
- NCT02537652
- Testing
- Blood pressure assessment
- Where
- 2 sites in United Kingdom
- Volunteers
- 29 people
- Sponsor
- Hampshire Hospitals NHS Foundation Trust
Blood Pressure
The Effects of L-Tyrosine on 24 Hour Blood Pressure and Heart Rate in Parkinson's Disease
The investigators are observing the effects 2,000 mg of L-tyrosine will have on 24 hour blood pressure fluctuations in individuals with Parkinson's disease.
- Trial name
- NCT02259049
- Testing
- L-tyrosine, Sugar Pill
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- New York Institute of Technology
Hypertension
One-Year Safety and Tolerability Study of Azilsartan Medoxomil in Participants With Essential Hypertension
This purpose of this study is to evaluate the long-term safety and tolerability of azilsartan medoxomil in individuals with essential hypertension.
- Trial name
- NCT00695955
- Testing
- Azilsartan medoxomil with or without add-on chlorthalidone, Azilsartan medoxomil with or without add-on hydrochlorothiazide
- Where
- 41 sites in United States, Chile and 1 more
- Volunteers
- 669 people
- Sponsor
- Takeda
Hypertension, Healthy
Effect of Oral Caffeine and L-Citrulline Supplementation on Arterial Function in Healthy Males
Caffeine is an exceedingly popular and consumed pharmacological agent. Although caffeine is primarily consumed from coffee and tea beverages, it is also available in other forms such as sodas, energy drinks, tablets and capsules.
- Trial name
- NCT02214290
- Testing
- Caffeine, L-citrulline
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Florida State University
Weight, Blood Pressure
Interactive Web Program and Health Coaching for Prehypertensive Adults
This project will develop and evaluate an interactive blood pressure self-management program for adults with prehypertension. The program will target blood pressure self-monitoring and the five proven lifestyle modifications…
- Trial name
- Prehype (NCT02637063)
- Testing
- BlipHub mobile-web app, BlipHub mobile-web app + health coaching, Usual care
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Oregon Center for Applied Science, Inc.
Diabetes, Hypertension
Change of Lifestyle in Elderly Patients With Type 2 Diabetes and Systemic Arterial Hypertension
Evaluate the effect of lifestyle modification through the adoption of a DASH diet, with and without physical activity guidance, on blood pressure and insulin sensitivity in elderly patients with type 2 diabetes and hypertension.
- Trial name
- NCT04863755
- Testing
- DASH, DASHPED
- Where
- Brazil
- Volunteers
- 37 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Liver Tumor; Surgery, Primary Liver Tumor, Metastatic Liver
Stroke Volume Variation Versus Central Venous Pressure Guidance for Reducing Perioperative Blood Loss During Open Liver Resection, A Non-inferiority Randomized Controlled Trial
Liver resection is a major surgery that can be associated with significant intraoperative blood loss and blood transfusion. Among high-volume centers, median intraoperative blood loss ranges between 300-800 ml.
- Conditions
- Liver Tumor; Surgery, Primary Liver Tumor, Metastatic Liver, Primary Liver Cancer, Liver Resection
- Trial name
- NCT06905015
- Testing
- High SVV-guided fluid management, Low CVP-guided fluid management
- Where
- Thailand
- Volunteers
- 70 people
- Sponsor
- Chiang Mai University
Chronic Kidney Diseases
Sleep-time Blood Pressure and Risk of CKD Progression
The SLEEP-BP-CKD Study has been designed to specifically test the following primary hypotheses: (i) Specific ABPM-derived parameters, in particular the asleep SBP mean and/or the sleep-time relative SBP decline, are significant…
- Trial name
- SLEEP-BP-CKD (NCT05189418)
- Testing
- Ambulatory blood pressure monitoring (ABPM), Home blood pressure monitoring (HBPM)
- Where
- 10 sites in Spain
- Volunteers
- 210 people
- Sponsor
- University of Vigo
Circadian Rhythm, Blood Pressure
Circadian Mechanisms Underlying Non-Dipping Blood Pressure in Blacks
This study seeks to examine central and peripheral circadian mechanisms in Blacks with appropriately dipping systolic blood pressure (blood pressure that dips by at least 10%) compared with non-dipping systolic blood pressure…
- Trial name
- NCT03934255
- Testing
- Constant Routine Protocol
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Neurovascular Disorder
Adherence to Blood Pressure Diaries With Personalized Visuals
This trial randomizes patients with a neurovascular diagnosis to a type of blood pressure diary for secondary stroke prevention (conventional blood pressure diary or blood pressure diary including patient-provided images).
- Trial name
- NCT06189378
- Testing
- Inclusion of patient-provided pictures into blood pressure diaries, Conventional blood pressure diary
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- Medical University of Vienna
Exposure to Man-made Visible Light
Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 1 of 7)
NOTE: This is the first of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674.
- Trial name
- NCT02882516
- Testing
- Visible light exposure
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bern
Obstructive Sleep Apnea, Hypertension
Effect of Selective and Nonselective Cyclooxygenase Enzyme Inhibition on Arterial Blood Pressure and Cerebral Blood Flow With Exposure to Intermittent Hypoxia in Humans
The study has been designed to assess the effect of cyclooxygenase inhibition on blood pressure, cerebral blood flow, ventilation and renal hemodynamics following chronic intermittent hypoxia exposure.
- Conditions
- Obstructive Sleep Apnea, Hypertension, Cardiovascular Diseases, Stroke
- Trial name
- NCT01280006
- Testing
- Intermittent hypoxia, Indomethacin, Celecoxib
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Hypertension, Diabetes Mellitis
Community Partnership to Examine Racial and Ethnic Differences in Health Care for Hypertension and Diabetes
Hypertension and diabetes are among the most common chronic diseases in the United States. Racial and ethnic minority groups are more at risk for these diseases than the Caucasian population.
- Trial name
- CHAMPP (NCT00379652)
- Testing
- Medical Practice Improvement, Patient Education and Support, Combination Intervention to Include Medical Practice Improvement and Patient Education and Support
- Where
- 2 sites in United States
- Volunteers
- 1,204 people
- Sponsor
- Harvard Medical School (HMS and HSDM)
Diabetes Mellitus, Type 2, Hypertension
Short-term Effects of Perindopril-amlodipine Versus Perindopril-indapamide in Type 2 Diabetes
This was a double-blinded randomized controlled trial of 24-hour blood pressure control in sub Saharan type 2 diabetes patients, newly diagnosed for hypertension.
- Trial name
- NCT03747978
- Testing
- Perindopril and Amlodipine, Perindopril-indapamide
- Where
- Cameroon
- Volunteers
- 30 people
- Sponsor
- Yaounde Central Hospital
Cardiovascular Diseases, Heart Diseases
Blood Pressure Tracking--Childhood to Young Adulthood
To extend analyses of blood pressure (BP) tracking to a period that spanned childhood and young adulthood. Data were used from the same cohort of 339 children who had been followed for nine to twelve years in a previous study.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension
- Trial name
- NCT00005421
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
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