Clinical trials: Blood Pressure Management
Hypertension
Ambulatory vs Office BP Management Usual Care for Diagnosing and Managing Hypertension: A Pilot Study
The purpose of this study is to compare the effectiveness of ambulatory blood pressure monitoring to usual care (blood pressure measurement in the office) in diagnosing and managing hypertension.
- Trial name
- NCT02121041
- Testing
- Amlodipine, Chlorthalidone, Losartan
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Anthony J Viera, MD, MPH
Cerebrovascular Accident
Blood Pressure Lowering in Acute Stroke Trial (BLAST)
Patients who are suffering from a stroke often present to the hospital with elevated blood pressure. Elevated blood pressure in the setting of stroke increases the risk of brain swelling or bleeding into the brain.
- Trial name
- NCT00627991
- Testing
- Valsartan
- Where
- United States
- Sponsor
- Stanford University
Weight Loss
Weight Management Demonstration Project: HEALTH
The study investigated the effectiveness and cost-effectiveness of a cognitive and behavioral weight management program, complemented by an interactive Web site and brief telephone coaching, implemented among TRICARE…
- Trial name
- HEALTH (NCT01307280)
- Testing
- RCT1, RCT2, RCT3
- Where
- 3 sites in United States
- Volunteers
- 2,395 people
- Sponsor
- RTI International
Hypertensive Disorders of Pregnancy, Chronic Hypertension in Pregnancy
MH-Rx Study (Baby on Board: Check-in on You, Your Medication, & Your Blood Pressure)
This randomized controlled trial will evaluate whether adding Community Health Worker (CHW)/Social Worker (SW)-led support for non-medical health related needs (NMHRN) and clinician-led Medication Therapy Management (MTM) to…
- Conditions
- Hypertensive Disorders of Pregnancy, Chronic Hypertension in Pregnancy, Gestational Hypertension
- Trial name
- NCT07842341
- Testing
- Community Health Worker (CHW)/Social Worker (SW)-led non-medical health related needs (NMHRN) intervention + Clinician-Led Medication Therapy Management (MTM) with remote blood pressure monitoring, Active Comparator (Control group)
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- Texas Southern University
Hypertension, Cardiovascular Disease
Management of Hypertension and Multiple Risk Factors to Enhance Cardiovascular Health
Background: Hypertension is a serious public health problem responsible for significant mortality and morbidity from cardiovascular disease. In Singapore, 1 in 4 adults age 30 years or older suffer from hypertension.
- Trial name
- NCT02972619
- Testing
- Structured Multicomponent Intervention (MCI)
- Where
- Singapore
- Volunteers
- 1,000 people
- Sponsor
- Duke-NUS Graduate Medical School
Hypertension, Blood Pressure Monitoring
Monitoring Blood Pressure at Home and Pharmacy Telehealth Among People Living With HIV
The overall goal of this project is to determine if measuring blood pressure at home and staying in contact with a team of pharmacists and physicians to manage participants' blood pressure is useful.
- Trial name
- REMAP-BP-HIV (NCT07849595)
- Testing
- Remote Blood Pressure Monitoring + Telehealth
- Volunteers
- 572 people
- Sponsor
- University of Alabama at Birmingham
Diabetes, Hyperlipidemia
The Health Outcomes Management and Evaluation (HOME) Study
There is an urgent need to develop practical, sustainable approaches to improving medical care for persons treated in community mental health settings.
- Conditions
- Diabetes, Hyperlipidemia, Heart Disease, High Blood Pressure
- Trial name
- HOME (NCT01228032)
- Testing
- Care team
- Where
- United States
- Volunteers
- 447 people
- Sponsor
- Emory University
Diabetes Mellitus, Type 2
Dulce Digital-Me: An Adaptive mHealth Intervention for Underserved Hispanics With Diabetes
This study will compare Dulce Digital (i.e., the investigators' proven-effective combination of "one-size-fits-all" educational text messages and nurse monitoring of patient-transmitted blood glucose values) and Dulce Digital-Me…
- Trial name
- DD-Me (NCT03130699)
- Testing
- Dulce Digital, Dulce Digital-Me (Automated Delivery), Dulce Digital-Me (Medical Assistant)
- Where
- 2 sites in United States
- Volunteers
- 310 people
- Sponsor
- Scripps Whittier Diabetes Institute
Hypertension
Yoga for a Healthy Heart
The Yoga for a Healthy Heart study will address various barriers to both medication management and blood pressure regulation for African American patients with hypertension.
- Trial name
- YHH (NCT06155240)
- Testing
- Therapeutic yoga
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- The Cleveland Clinic
Infant, Newborn, Infant, Low Birth Weight
Early Blood Pressure Management in Extremely Premature Infants
This trial tests the feasibility of enrolling 60 extremely preterm infants in a randomized, double-blinded study of blood pressure management within 12 months.
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Trial name
- ELGAN BP (NCT00874393)
- Testing
- Dopamine, Hydrocortisone
- Where
- 17 sites in United States
- Volunteers
- 10 people
- Sponsor
- NICHD Neonatal Research Network
Blood Pressure
The GUARDIAN Trial - Vasopressor Sub-Study
This is a sub-study of the overall GUARDIAN trial (NCT04884802) in which some GUARDIAN trial participants will be additionally randomized to norepinephrine or phenylephrine infusion to maintain the designated target…
- Trial name
- NCT04934748
- Testing
- Routine Blood Pressure Management, Tight Blood Pressure Management, Phenylephrine
- Where
- 11 sites in United States, China and 2 more
- Volunteers
- 6,254 people
- Sponsor
- The University of Texas Health Science Center, Houston
General Surgery
The GUARDIAN Pilot Trial
The treatments will be: 1) norepinephrine or phenylephrine infusion to maintain intraoperative MAP ≥85 mmHg, delayed resumption of chronic antihypertensive medications, and a target ward MAP ≥80 mmHg (tight pressure management)…
- Trial name
- GUARDIAN (NCT04789733)
- Testing
- Tight pressure management, Routine pressure management
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The Cleveland Clinic
Pediatric Perioperative Blood Pressure Management
Assessment of Efficacy, Safety and Dosing of Clevidipine in Pediatric Participants Undergoing Surgery (PIONEER)
Evaluate the efficacy, safety, and dosing of clevidipine as an intravenous (IV) infusion for blood pressure (BP) management in paediatric participants in the perioperative setting.
- Trial name
- PIONEER (NCT01938547)
- Testing
- clevidipine
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Hypertension, Cardiovascular Disease
Detecting and Treating High Blood Pressure in Aboriginal Population and Low and Middle Income Countries
Heart disease and stroke are the number one killers world-wide. When someone has hypertension, the constantly elevated blood pressure damages their blood vessels and the organs that they supply blood to.
- Conditions
- Hypertension, Cardiovascular Disease, Diabetes
- Trial name
- DREAM-GLOBAL (NCT02111226)
- Testing
- SMS text messaging
- Where
- Canada
- Volunteers
- 360 people
- Sponsor
- Sunnybrook Health Sciences Centre
Hypertension
Study of a Comprehensive Intelligent Hypertension managEment SyStem
This cluster randomized controlled trial aims to evaluate the efficacy of a comprehensive intelligent hypertension management system (CHESS) in blood pressure lowering in primary health care (PHC) settings of China.
- Trial name
- CHESS (NCT05605418)
- Testing
- CHESS intervention
- Where
- China
- Volunteers
- 1,666 people
- Sponsor
- China National Center for Cardiovascular Diseases
Hypertension, Emergencies
The Effect of Pre-discharge Blood Pressure of Patients With Asymptomatic Severe Hypertension in Emergency Department
The current guideline of asymptomatic severe hypertension (ASH) treatment in emergency department (ED) recommends through low level of evidence that the patients should not be rapidly decreased their BP in ED but instead receive…
- Conditions
- Hypertension, Emergencies, Asymptomatic Conditions
- Trial name
- NCT02534324
- Testing
- Antihypertensive meds
- Where
- Thailand
- Volunteers
- 146 people
- Sponsor
- Chulalongkorn University
Hypotension
PeRsonalized Blood prEssure Management on Postoperative Complications and Mortality in hIgh-risk Patients Undergoing Major Non-cardiac Surgery
High-risk populations, particularly elderly individuals and patients with cardiovascular comorbidities, exhibit markedly elevated incidences of postoperative myocardial injury (MINS), acute kidney injury (AKI), and mortality.
- Trial name
- PREMIUM (NCT06952387)
- Testing
- Personalized blood pressure management, Routine blood pressure management
- Where
- 7 sites in China
- Volunteers
- 1,624 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Colorectal Cancer, Intraoperative Hemodynamic Management
MAP- Versus Cardiac Index-Guided Hemodynamic Management in Colorectal Surgery
This prospective randomized trial aims to compare the effects of two intraoperative hemodynamic management strategies on early postoperative renal function in patients undergoing colorectal surgery.
- Trial name
- NCT07609680
- Testing
- Mean Arterial Pressure-Guided Hemodynamic Management, Cardiac Index-Guided Hemodynamic Management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Etlik City Hospital
Hypertension, High Blood Pressure
Optimizing Linkage and Retention to Hypertension Care in Rural Kenya
Cardiovascular disease (CVD) is the leading cause of death in sub-Saharan Africa among adults above age 30. The prevalence of hypertension, a major risk factor for CVD, is increasing over time in sub-Saharan Africa, exerting a…
- Trial name
- NCT01844596
- Testing
- behavioral communication strategy, Behavioral communication strategy, plus smartphone-based tool
- Where
- Kenya
- Volunteers
- 1,455 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Hypertension, Electronic Health Record
Virtual Hypertension Management Pilot
Investigators are examining the quality improvement impact of providing patients with a an electronic health record-connected blood pressure cuff.
- Conditions
- Hypertension, Electronic Health Record, Digital Health
- Trial name
- NCT03291535
- Testing
- Connected-device, Usual care
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- Stanford University