Clinical trials: Blood Pressure Management
Hypertension
Home Blood Pressure Telemonitoring and Case Management to Control Hypertension
In this project we develop and implement an intervention to improve hypertension control in a primary care setting that takes advantage of new technology (home blood pressure telemonitoring) and team models of care (pharmacist…
- Trial name
- Hyperlink (NCT00781365)
- Testing
- Telemonitors and pharmacy management
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Hypertension
Pragmatic Trial Comparing Telehealth Care and Optimized Clinic-Based Care for Uncontrolled High Blood Pressure
This pragmatic trial will compare two team-based care models for managing hypertension, Best Practice Clinic-based Care and Telehealth Care with pharmacist management, in a large care system in Minnesota.
- Trial name
- NCT02996565
- Testing
- Best Practice Clinic-Based Care, Telehealth Care
- Where
- United States
- Volunteers
- 3,071 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Hypertension
Mobile Technology for Blood Pressure Management
The primary objective of this study is to assess the feasibility and effectiveness of a mobile-technology based system that integrates patient-facing and clinician-facing components to assist the management of hypertension.
- Trial name
- NCT04841317
- Testing
- Mobile technology intervention
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Stanford University
Hypotension and Shock
BP Management System User Acceptance Testing
This is a feasibility study for an investigational clinical decision support system ("the System") intended to optimize the management of blood pressure (BP) for patients during vasopressor infusion.
- Trial name
- NCT04688450
- Testing
- VIGORIS Blood Pressure Management Clinical Decision Support System
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Andrew Tomas Reisner
Spinal Cord Injury
Bowel Care and Cardiovascular Function After Spinal Cord Injury
The main goal of this project is to determine the effects of lidocaine lubricant on cardiovascular function during routine bowel care in individuals with spinal cord injury.
- Trial name
- NCT01567605
- Testing
- Lidocaine lubricant
- Where
- 2 sites in Canada
- Volunteers
- 13 people
- Sponsor
- Simon Fraser University
Hypertension
Ambulatory vs Office BP Management Usual Care for Diagnosing and Managing Hypertension: A Pilot Study
The purpose of this study is to compare the effectiveness of ambulatory blood pressure monitoring to usual care (blood pressure measurement in the office) in diagnosing and managing hypertension.
- Trial name
- NCT02121041
- Testing
- Amlodipine, Chlorthalidone, Losartan
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Anthony J Viera, MD, MPH
Diabetes Mellitus, Type 2
Dulce Digital-Me: An Adaptive mHealth Intervention for Underserved Hispanics With Diabetes
This study will compare Dulce Digital (i.e., the investigators' proven-effective combination of "one-size-fits-all" educational text messages and nurse monitoring of patient-transmitted blood glucose values) and Dulce Digital-Me…
- Trial name
- DD-Me (NCT03130699)
- Testing
- Dulce Digital, Dulce Digital-Me (Automated Delivery), Dulce Digital-Me (Medical Assistant)
- Where
- 2 sites in United States
- Volunteers
- 310 people
- Sponsor
- Scripps Whittier Diabetes Institute
Pediatric Perioperative Blood Pressure Management
Assessment of Efficacy, Safety and Dosing of Clevidipine in Pediatric Participants Undergoing Surgery (PIONEER)
Evaluate the efficacy, safety, and dosing of clevidipine as an intravenous (IV) infusion for blood pressure (BP) management in paediatric participants in the perioperative setting.
- Trial name
- PIONEER (NCT01938547)
- Testing
- clevidipine
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Hypertension, Emergencies
The Effect of Pre-discharge Blood Pressure of Patients With Asymptomatic Severe Hypertension in Emergency Department
The current guideline of asymptomatic severe hypertension (ASH) treatment in emergency department (ED) recommends through low level of evidence that the patients should not be rapidly decreased their BP in ED but instead receive…
- Conditions
- Hypertension, Emergencies, Asymptomatic Conditions
- Trial name
- NCT02534324
- Testing
- Antihypertensive meds
- Where
- Thailand
- Volunteers
- 146 people
- Sponsor
- Chulalongkorn University
Hypertension, Pre Hypertension
Electronic Health Record-Based Clinical Decision Support to Improve Blood Pressure Management in Adolescents
The goal of this project is to improve detection and management of elevated blood pressure in adolescents. It (a) uses electronic health record (EHR) technology to deliver patient-specific clinical decision support (CDS) to…
- Conditions
- Hypertension, Pre Hypertension, Obesity
- Trial name
- NCT01760239
- Testing
- Clinical Decision Support (CDS)
- Where
- United States
- Volunteers
- 31,579 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Moderate to High-risk Noncardiac Surgery
Hypotension Prediction Index (HPI) SMART-BP Trial
A multicenter, randomized comparison of intraoperative hemodynamic management with or without a protocolized strategy utilizing Hypotension Prediction Index (HPI) software guidance during moderate-to-high-risk noncardiac surgery.
- Trial name
- NCT05105477
- Testing
- AcumenTM HPI Software Feature, Non-protocolized Standard of Care
- Where
- 11 sites in United States
- Volunteers
- 407 people
- Sponsor
- Edwards Lifesciences
Primary Aldosteronism, Hyperaldosteronism
A Study of CIN-107 in Adults With Primary Aldosteronism
This is a multicenter, open-label study in adult patients with PA to evaluate the effectiveness and safety of CIN-107 after up to 12 weeks of treatment (Part 1), and then for eligible, consenting patients follow patients in Part…
- Trial name
- NCT04605549
- Testing
- CIN-107 2 mg dosing, CIN-107 4 mg dosing, CIN-107 8 mg dosing
- Where
- 10 sites in United States
- Volunteers
- 15 people
- Sponsor
- AstraZeneca
Hypertension
Management of Uncontrolled Hypertension (HTN)
In this study, investigators will compare chronotherapy to ABPM. Data collected will include hypertension drug therapy regimen prior to and during the study, timing of medication administration, and dose, along with the patient's…
- Trial name
- NCT02922023
- Testing
- Ambulatory blood pressure monitor (ABPM), Chronotherapy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Florida
Chronic Kidney Diseases, High Blood Pressure
Diet and Hypertension Management in African Americans With Chronic Kidney Disease
The purpose of this study is to determine cultural and disease-related barriers and facilitators to following the Dietary Approaches to Stop Hypertension (DASH) dietary pattern among Black Americans with moderate chronic kidney…
- Trial name
- NCT04084574
- Testing
- DASH diet counseling
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Duke University
Hypertension
MK-0954E Study in Participants With Hypertension (MK-0954E-357)
This study is being done to evaluate the efficacy, safety, and tolerability of losartan potassium 50 mg (L50) + hydrochlorothiazide 12.5 mg (H12.5) + amlodipine besylate 5 mg (A5) (MK-0954E).
- Trial name
- NCT01302691
- Testing
- losartan potassium + hydrochlorothiazide + amlodipine besylate (MK-0954E), Losartan potassium, Amlodipine besylate
- Volunteers
- 327 people
- Sponsor
- Merck Sharp & Dohme LLC
Hypertension
Phase I Study to Investigate the Effect on the Blood Pressure After Oral Administration of SK3530 and Amlodipine
To assess the pharmacodynamic effects of co-administrated SK3530 (PDE5 inhibitor) and Amlodipine, phase I study in Hypertensive patient was designed.
- Trial name
- NCT00626743
- Where
- 2 sites in South Korea
- Volunteers
- 13 people
- Sponsor
- SK Chemicals Co., Ltd.
Hypertension
Valsartan Intensified Primary Care Reduction of Blood Pressure Study
This study will assess the efficacy of an intensive blood pressure management strategy compared to usual care in a primary care (general practice) setting.
- Trial name
- VIPER-BP (NCT00902304)
- Testing
- Valsartan and hydrochlorothiazide (HCTZ) - monotherapy, Valsartan and amlodipine, Usual care
- Where
- 3 sites in United States, Australia
- Volunteers
- 2,337 people
- Sponsor
- Novartis Pharmaceuticals
Pre Eclampsia
Pilot Assessment of an Auto Blood Pressure Monitor
The purpose of the study is to help make a lower cost automatic blood pressure monitor device for diagnosis and monitoring of pre-eclampsia in pregnant women, where automatic blood pressure monitoring is limited or not available.
- Trial name
- NCT02258256
- Testing
- Sphygmo
- Where
- Malawi
- Volunteers
- 11 people
- Sponsor
- William Marsh Rice University
Hypertension
Self-management of Blood Pressure Medication for Hypertensive Veterans
Hypertension is the most common medical problem among US Veterans. Treatment is available and effective, but control rates remain under 75%.
- Trial name
- NCT03224624
- Testing
- self-management protocol for hypertension care
- Where
- 2 sites in United States
- Volunteers
- 232 people
- Sponsor
- VA Office of Research and Development
Intraoperative Hypotension
Hypotension Prediction Index for Blood Pressure Management
Design: Single-center randomized comparison of invasive arterial pressure monitoring vs. arterial pressure monitoring combined with Acumen Hypotension Prediction Index (HPI) software guidance on intraoperative hypotension…
- Trial name
- HPI (NCT03610165)
- Testing
- Acumen HPI-enabled EV1000 screen, Control
- Where
- United States
- Volunteers
- 214 people
- Sponsor
- The Cleveland Clinic