Clinical trials: Blood Pressures
Blood Pressure
WBPS A Prospective, Method Comparison, Proof of Concept Study
The study will evaluate the accuracy of BP measurements by a new algorithm to be embedded to the existing CE-marked WinPack device, compared to two reference devices (one oscillometric and one volume-clamp device), in healthy…
- Trial name
- WBPS (NCT02934386)
- Testing
- WinMedical WinPack device
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- CSEM Centre Suisse d'Electronique et de Microtechnique SA - Recherche et Developpement
Non Invasive Blood Pressure
Philips Non-Invasive Blood Pressure Validation Study
The purpose of this study is to provide supporting documentation of the blood pressure performance for the Philips EarlyVue VS30 monitor on the intended adult and pediatric population.
- Trial name
- NCT06682312
- Testing
- Non-invasive blood pressure
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
No Specific Conditions Are Being Examined
Comparison Study for Hemodynamic Parameters Generated by Vitalstream Relative to Appropriate Gold Standard References in Different Clinical Settings, (OR, EP Lab Etc.).
The goal of the proposed study is to test the capability of the Vitalstream monitor's continuous blood pressure tracking ability against Gold Standard.
- Trial name
- NCT07775469
- Testing
- Vitalstream
- Volunteers
- 60 people
- Sponsor
- CareTaker Medical LLC
Otherwise Healthy Individuals With Systolic Blood Pressure (SBP) From 110 to 139 mmHg and Low-density Lipoprotein Cholesterol (LDL-C) ≥ 100 mg/dL
A Study to Evaluate COR-2003 as Monotherapy and Co-Administered With COR-1004 in Adult Volunteers
This clinical trial has two parts. In Part A, the goal is to learn about the safety and tolerability of COR-2003 when it is given alone.
- Trial name
- NCT07858019
- Testing
- COR-2003, COR-1004 + COR-2003
- Where
- 2 sites in Australia, New Zealand
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Corsera Health
Prehypertension, Hypertension, Stage I
A Prospective Study of B244 Delivered as a Topical Spray to Determine Safety and Efficacy in Subjects With Elevated Blood Pressure
The purpose of this study is to evaluate and compare the efficacy of B244 in treating patients with hypertension.
- Trial name
- NCT02998840
- Testing
- B244, Vehicle
- Where
- 10 sites in United States
- Volunteers
- 132 people
- Sponsor
- AOBiome LLC
Hypertension
A Study to Assess the Safety, Tolerability and Efficacy of IONIS-AGT-LRx in Hypertensive Participants With Uncontrolled Blood Pressure
The purpose of this study was to evaluate the effect of IONIS-AGT-LRx compared to placebo on seated automated office systolic blood pressure (SBP) from baseline to Study Day 85 in uncontrolled hypertensive participants on ≥ 3…
- Trial name
- ASTRAAS (NCT04714320)
- Testing
- IONIS-AGT-LRx
- Where
- 50 sites in United States, Canada
- Volunteers
- 160 people
- Sponsor
- Ionis Pharmaceuticals, Inc.
Coronary Artery Disease
Vericiguat Drug-drug Interaction With Nitroglycerin in Stable Coronary Artery Disease Patients
This study is intended to investigate the effect of nitroglycerin on vericiguat in patients with stable coronary artery disease (CAD). Nitroglycerin is the standard therapy to treat acute crisis of angina.
- Trial name
- VENICE (NCT02617550)
- Testing
- Vericiguat (BAY1021189), Nitroglycerin
- Where
- 6 sites in Germany
- Volunteers
- 36 people
- Sponsor
- Bayer
Hypertension
A Study to Describe Vascular and Renal Effects and Safety of Valsartan in Patients With High Blood Pressure
One hundred twenty patients with arterial hypertension and albuminuria (some amount of albumin in urine) are given valsartan 80 mg and then160 mg to normalize blood pressure.
- Trial name
- NCT00171353
- Testing
- valsartan
- Where
- Switzerland
- Volunteers
- 109 people
- Sponsor
- Novartis
Blood Pressure
Blood Pressure Monitor Clinical Test (Cuff Range: 13.5cm-19.5cm）
The purpose of this study is to verify the accuracy of the blood pressure cuffs with blood pressure monitor device. Cuff circumference is 13.5cm-19.5cm.
- Trial name
- NCT06117787
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Andon Health Co., Ltd
Autonomic Dysfunction, Orthostatic Intolerance
Continuous and Non-invasive Measurements by Task Force® CORE/CARDIO in Autonomic Function Testing (AFT)
Background: The investigational device, "Task Force® CORE" (TFC, CNSystems Medizintechnik GmbH, Graz, Austria) together with the "Task Force® CARDIO" (TFCARDIO, CNSystems Medizintechnik GmbH, Graz, Austria) medical device…
- Trial name
- NCT05977335
- Testing
- Autonomic Function Testing
- Volunteers
- 75 people
- Sponsor
- CNSystems Medizintechnik GmbH
Hypertension
Comparison of Sevikar® and the Combination of Perindopril/Amlodipine on Central Blood Pressure
Comparison of the combination of amlodipine with an angiotensin receptor blocker or an angiotensin converting inhibitor, on central arterial blood pressure in patients with hypertension and additional risk factors.
- Trial name
- NCT01101009
- Testing
- Perindopril + amlodipine + if necessary, hydrochlorothiazide, olmesartan/amlodipine + hydrochlorothiazide, if necessary.
- Where
- 15 sites in Spain
- Volunteers
- 486 people
- Sponsor
- Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company
Hypertension
Safety/Efficacy of Combo Therapy With Aliskiren & Hydrochlorothiazide vs Therapy With Hydrochlorothiazide Alone in Patients With Hypertension
The purpose of this trial is to evaluate the safety and efficacy of combination therapy of aliskiren/hydrochlorothiazide (HCTZ) 150/25 mg and 300/25 mg compared with HCTZ 25 mg in patients with hypertension who do not show…
- Trial name
- NCT00387517
- Testing
- Aliskiren/HCTZ
- Where
- 2 sites in United States, Germany
- Volunteers
- 726 people
- Sponsor
- Novartis
Hypertension
Blood Pressure Lowering Ability and Safety of an Olmesartan and Amlodipine Based Treatment Regimen in Patients With Stage I and Stage II Hypertension
This study will be conducted to assess the efficacy and safety of an amlodipine/olmesartan treatment regimen in stage 1 and stage 2 hypertensive subjects.
- Trial name
- NCT00527514
- Testing
- Amlodipine, Olmesartan medoxomil plus amlodipine
- Where
- 18 sites in United States
- Volunteers
- 185 people
- Sponsor
- Daiichi Sankyo
Obesity, Intra-Abdominal Fat
Effect of a Probiotic on Visceral Fat Accumulation
The study's main objective is to investigate if an extract containing the probiotic Bifidobacterium animalis subsp. lactis BPL1 (CECT 8145) has a positive effect on the accumulation of abdominal visceral fat in people with…
- Conditions
- Obesity, Intra-Abdominal Fat, Subcutaneous Fat, Abdominal
- Trial name
- BIFFAT (NCT02921217)
- Testing
- Active Probiotic, Inactivated probiotic, Control
- Where
- Spain
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Biopolis S.L.
Hypertension
A Controlled Study to Investigate the Effect of Multi-wave Light Emitting Diode (LED) Bed on Blood Pressure and Endothelial Function
The objective of this multi-center study is to investigate the effect of a multi-wave LED light bed on blood pressure and endothelial function in pre-hypertensive and mildly hypertensive adults.
- Trial name
- NCT04006158
- Testing
- LED bed
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- LED Intellectual Properties, LLC
Hypertension
Efficacy and Safety of Valsartan/Amlodipine Combination in Patients With Severe Hypertension
This study will assess the effectiveness and safety of different combination antihypertensive treatments in patients with severe hypertension
- Trial name
- NCT00171535
- Testing
- valsartan/amlodipine
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Novartis
Essential Hypertension
Efficacy and Safety of Valsartan/Amlodipine Compared to Amlodipine in Patients With Essential Hypertension
This study was designed to compare the efficacy, tolerability, and safety of the combination valsartan/amlodipine 160/5 mg versus amlodipine 10 mg in patients with essential hypertension not adequately controlled (defined as mean…
- Trial name
- NCT00437645
- Testing
- Valsartan 160 mg capsules, Amlodipine 5 mg capsules
- Where
- 12 sites in Argentina, Chile and 10 more
- Volunteers
- 1,183 people
- Sponsor
- Novartis Pharmaceuticals
High Blood Pressure
Effects of Combination Therapy With Alpha-1 Blocker (Bunazosin or Doxazosin) in the Treatment of Patients With Mild to Moderate Essential Hypertension
The purpose of this study is to investigate the efficacy and safety of Bunazosin with Valsartin compared to Doxazosin with Valsartin for patients with mild to moderate essential hypertension accompanied by metabolic syndrome.
- Trial name
- NCT00130156
- Testing
- Bunazosin, Doxazosin, Valsartin
- Where
- Taiwan
- Volunteers
- 93 people
- Sponsor
- Eisai Inc.
Arthritis, Juvenile Rheumatoid
A Study To Evaluate The Effects Of Celecoxib (Celebrex®) Or Naproxen On Blood Pressure In Pediatric Subjects
This Is A Multicenter, Active-Controlled Trial To Evaluate The Effects Of Celecoxib (Celebrex®) Or Naproxen On Blood Pressure In Pediatric Subjects With Juvenile Idiopathic Arthritis
- Trial name
- NCT00807846
- Testing
- Celecoxib, Naproxen
- Where
- 39 sites in United States, Chile and 8 more
- Volunteers
- 201 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Hypertension, Cardiovascular Diseases
Evaluation of the Effect of Telmisartan (Micardis® 80 mg/ MicardisPlus® 80/12.5 mg) on Blood Pressure and Cardiovascular Risk Factor Index in High Risk Hypertensive Patients
The study is designed to evaluate the effect of treatment with Micardis/MicardisPlus on blood pressure and its ability to reduce different indicated cardiovascular risks.
- Trial name
- NCT00904371
- Where
- 36 sites in Slovenia
- Volunteers
- 211 people
- Sponsor
- Boehringer Ingelheim