Clinical trials: Blood Pressures
Hypertension
Efficacy and Safety of Azilsartan in Subjects With Essential Hypertension
The purpose of this study is to determine the safety and efficacy of azilsartan, once daily (QD), in subjects with essential hypertension.
- Trial name
- NCT00759551
- Testing
- Azilsartan, Olmesartan
- Volunteers
- 555 people
- Sponsor
- Takeda
Blood Pressure, Heart Disease
Accuracy of a Cuffless Photoplethysmography (PPG) Chest-Patch Monitor for 24-hour Ambulatory Blood Pressure Monitoring (ABPM)
This study aims to validate the accuracy and reliability of blood pressure (BP) estimates obtained over 24 hours using a PPG-based chest-patch device compared to the gold standard ambulatory blood pressure monitoring (ABPM)…
- Conditions
- Blood Pressure, Heart Disease, Hypertension (HTN), Blood Pressure Monitoring
- Trial name
- PPG ABPM (NCT07240831)
- Testing
- Model BB-613WP
- Where
- 11 sites in United States, Israel and 1 more
- Volunteers
- 612 people
- Sponsor
- Biobeat Technologies Ltd.
Hypertension
Efficacy and Safety of Aliskiren Administered in Combination With Amlodipine Versus Amlodipine Alone in African American Patients With Stage 2 Hypertension
The purpose of the study is to evaluate the BP-lowering efficacy of the combination of aliskiren and amlodipine, as initial therapy, compared to amlodipine monotherapy in African American patients with Stage II hypertension.
- Trial name
- AACESS (NCT00853957)
- Testing
- Aliskiren/Amlodipine, Amlodipine
- Where
- 9 sites in United States
- Volunteers
- 443 people
- Sponsor
- Novartis
High Blood Pressure (Hypertension).
Factorial Study of Metoprolol Succinate TOPROL-XL (324A)
The purpose of this research study is to determine if treatment with the combination of metoprolol succinate and hydrochlorothiazide is more effective at lowering blood pressure than treatment with either of the two drugs alone.
- Trial name
- NCT00642096
- Testing
- Metoprolol Succinate, Hydrochlorothiazide
- Volunteers
- 1,900 people
- Sponsor
- AstraZeneca
Hypertension, Postmenopause
Effect of Angeliq on Blood Pressure (BP) in Postmenopausal Hypertensive Women
The objective of the study is to evaluate the effects of Angeliq on BP over a period of 8 weeks in postmenopausal women who may benefit from hormone replacement therapy (HRT) for the relief of vasomotor symptoms and who have…
- Trial name
- NCT00102141
- Testing
- Angeliq (Drospirenone/17ß-estradiol, BAY86-4891)
- Volunteers
- 750 people
- Sponsor
- Bayer
Hypertension
Investigating the Effect of Telmisartan (Micardis®) on the Average 24h Blood Pressure of Therapy-naive and Therapy-experienced Patients
Practical experience report (PER) investigating the effect of Micardis® on the average 24h blood pressure of therapy-naive and therapy-experienced patients
- Trial name
- NCT00879411
- Testing
- Micardis
- Volunteers
- 670 people
- Sponsor
- Boehringer Ingelheim
Blood Pressure
Assessing Innovative Wireless and Wearable Sensors for Continuous Blood Pressure Measurement in Obese Pregnant Women
This study is a prospective study targeting at least 20 obese and super-obese patients admitted to Labor \& Delivery (L\&D) for delivery at UNC Medical Center.
- Trial name
- NCT05790265
- Testing
- ANNE One
- Volunteers
- 20 people
- Sponsor
- Sibel Health Inc.
Hypertension
A Safety and Tolerability Study of Azilsartan Medoxomil in Participants With Essential Hypertension
The purpose of this study is to determine the long term safety and tolerability of azilsartan medoxomil, once daily (QD), in participants with Essential Hypertension.
- Trial name
- NCT00696384
- Testing
- Azilsartan medoxomil, Azilsartan medoxomil, with or without chlorthalidone and other non-angiotensin II receptor blocker antihypertensive medications.
- Where
- 45 sites in United States, Argentina and 1 more
- Volunteers
- 418 people
- Sponsor
- Takeda
Blood Pressure, Blood Pressure Measurement
Automated Non-Invasive Blood Pressure Study
The purpose of the study is to design and implement methods to make an algorithm to estimate blood pressure changes.
- Trial name
- NCT07790458
- Where
- 2 sites in Finland
- Volunteers
- 50 people
- Sponsor
- GE Healthcare
Hypertension
A Randomized, Double-blind, Placebo Controlled Comparison of Telmisartan Hydrochlorothiazide (HCT) and Valsartan HCT in Hypertension (HTN) Stage I/II Patients
The primary objective of this study is to compare the effectiveness of telmisartan 80 mg/hydrochlorothiazide 25 mg [Micardis HCT] to valsartan 160 mg/hydrochlorothiazide 25 mg [Diovan HCT] and placebo in the treatment of Stage 1…
- Trial name
- NCT00240448
- Testing
- telmisartan 80 mg/hydrochlorothiazide 25 mg, valsartan 160 mg/hydrochlorothiazide 25 mg
- Where
- 100 sites in United States
- Volunteers
- 1,109 people
- Sponsor
- Boehringer Ingelheim
Obesity, Hypertension
A Study of Efficacy and Safety of Topiramate in the Treatment of Obese Patients With Mild to Moderate Essential Hypertension
The purpose of this study is to compare the efficacy and safety of daily topiramate (96mg or 192mg) versus placebo in obese patients with mild to moderate high blood pressure.
- Trial name
- NCT00236665
- Testing
- topiramate
- Volunteers
- 531 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Hypertension, Dyslipidemia
An Observational Study to Evaluate Effectiveness and Safety of Amosartan Q Tablet
This study was to evaluate the therapeutic effect and safety of amosartan Q tablet administration in adult patients with hypertension and dyslipidemia.
- Trial name
- NCT05450575
- Testing
- Amosartan Q tablet
- Where
- South Korea
- Volunteers
- 5,400 people
- Sponsor
- Hanmi Pharmaceutical Company Limited
Hypertension
A Safety and Efficacy Trial of the Combination of Aliskiren / Hydrochlorothiazide (HCTZ)(300/12.5 mg and 300/25 mg) Compared to Aliskiren 300 mg in Hypertensive Patients
Evaluate the diastolic blood pressure lowering effect of combination of aliskiren 300 mg and HCTZ (12.5 mg and 25 mg) in hypertensive patients who do not show sufficient blood pressure response to aliskiren 300 mg.
- Trial name
- NCT00386139
- Testing
- Aliskiren/HCTZ
- Where
- 2 sites in United States, Germany
- Volunteers
- 881 people
- Sponsor
- Novartis
Hypertension
Efficacy and Safety of Valsartan, Hydrochlorothiazide and Amlodipine Combination Therapy in Hypertension
This study is designed to evaluate the efficacy and safety of the combination valsartan with hydrochlorothiazide and amlodipine in hypertensive patients previously treated with valsartan with hydrochlorothiazide and remaining…
- Trial name
- NCT00400777
- Testing
- Valsartan, hydrochlorothiazide and amlodipine
- Where
- Brazil
- Volunteers
- 460 people
- Sponsor
- Novartis
Hypogonadism, Male
Ambulatory Blood Pressure Monitoring (ABPM) Study in Hypogonadal Men
A Phase 4, multi-center, open-label, single-arm 24-hour Ambulatory Blood Pressure Monitoring (ABPM) study of Testosterone Cypionate Injection in Hypogonadal Men to assess change in 24-hour ambulatory blood pressure from Baseline…
- Trial name
- NCT07328542
- Testing
- Testosterone Cypionate Injection 200 mg/mL
- Where
- 6 sites in United States
- Volunteers
- 144 people
- Sponsor
- Azurity Pharmaceuticals
Hypertension, Renal
Trial on the Safety and Efficacy of MLS-101 in Patients With Uncontrolled Hypertension
A randomized, double-blind, placebo-controlled, dose-ranging, Phase II study to evaluate the safety, efficacy, and tolerability of MLS-101 in Subjects With Uncontrolled Hypertension
- Trial name
- Target-HTN (NCT05001945)
- Testing
- MLS-101 (Part I), MLS-101 (Part II)
- Where
- 44 sites in United States
- Volunteers
- 200 people
- Sponsor
- Mineralys Therapeutics Inc.
Healthy Volunteers
A Phase 1 TR-701 FA Study of Blood Pressure Response Post Tyramine Challenge
Phase 1 study to determine the effect of oral TR-701 FA on SBP response when administered with tyramine
- Trial name
- NCT01539473
- Testing
- TR-701 FA with Tyramine
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Trius Therapeutics LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Blood Pressure
Measurement of NonInvasive Blood Pressure in Neonates Through Adults and Special Populations
This study is required to demonstrate that the non-invasive blood pressure (NIBP) measurement algorithms on two commercially available multifunction hemodynamic acquisition modules, the Patient Data Module (PDM) equipped with the…
- Trial name
- MISSION (NCT02125331)
- Testing
- Device: Blood pressure monitoring with GE Healthcare CARESCAPE B650 Patient Monitor-Patient Side Module (PSM) or Patient Data Module (PDM)
- Where
- 4 sites in United States, India
- Volunteers
- 83 people
- Sponsor
- GE Healthcare
High Cardiac Output, Low Cardiac Output
Comparison Study of Non-invasive Measurement of Blood Pressure and Cardiac Output During Stress Echocardiography
The objectives of the clinical trial is to validate hemodynamic parameters (Blood pressure and Cardiac Output) generated by an application coupled with an off-the-shelf pulse oximeter.
- Trial name
- NCT02422342
- Testing
- Pulse Oximeter CMS50FW (Contec Medical)
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- HeartBeat Technologies LTD
Diabetes Mellitus, Type 2, Hypertension
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
This study is open to adults with type 2 diabetes, high blood pressure, and cardiovascular disease. People can join the study if they have these conditions and do not have a history of heart failure.
- Conditions
- Diabetes Mellitus, Type 2, Hypertension, Cardiovascular Diseases
- Trial name
- NCT07064473
- Testing
- Vicadrostat, Empagliflozin
- Where
- 1,142 sites in United States, Argentina and 49 more
- Volunteers
- 11,800 people
- Sponsor
- Boehringer Ingelheim