Clinical trials: Blood Pressures
Hypertension, Hypertrophy, Left Ventricular
The SILVER Study: Systolic Hypertension Interaction With Left Ventricular Remodeling
The purpose of this study is to evaluate the safety and efficacy of ALT-711 in the treatment of isolated systolic hypertension in a formal study in patients with left ventricular hypertrophy.
- Trial name
- NCT00045994
- Testing
- ALT-711
- Volunteers
- 180 people
- Sponsor
- Synvista Therapeutics, Inc
Hypertension
Blood Pressure Lowering of Aliskiren HCTZ Compared to HCTZ in Stage 2 Systolic Hypertension in Older Population
The purpose of the study is to evaluate the efficacy and safety of initial use of a fixed dose combination of aliskiren Hydrochlorothiazide (HCTZ) compared to Hydrochlorothiazide in older population with Stage 2 systolic…
- Trial name
- ACTION (NCT00760266)
- Testing
- Aliskiren, Hydrochlorothiazide
- Where
- United States
- Volunteers
- 451 people
- Sponsor
- Novartis
Hypertension, Hyperlipidemia
Amlodipine/Atorvastatin Combination to Reduce the Health Risk of High Blood Pressure and High Cholesterol Levels
The purpose of the study is to measure the effect of the amlodipine/atorvastatin combination pill in reducing both elevated blood pressure and cholesterol levels to levels suggested by guidelines
- Trial name
- GEMINI-AALA (NCT00143234)
- Testing
- Amlodipine/atorvastatin single pill
- Where
- 118 sites in Argentina, Australia and 25 more
- Volunteers
- 1,825 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Blood Pressure
ClearSight Baby Cuff
A prospective, single arm data collection study evaluating a prototype ClearSight finger cuff in pediatric patients.
- Trial name
- NCT06834516
- Testing
- ClearSight baby cuff
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- Edwards Lifesciences
Blood Pressure
Blood Pressure Monitor (BPM1) Clinical Test (Cuff Range: 15cm-24cm, 22cm-42cm, 40-48cm)
The purpose of this study is to verify the accuracy of the blood pressure cuffs with blood pressure monitor device. Cuff circumference is: 15-24cm, 22-42cm, 40-48cm
- Trial name
- NCT07094152
- Where
- China
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Andon Health Co., Ltd
Hypertension
Evaluation of Atacand® (Candesartan) in Daily Medical Practice
This open label, non-interventional study is to show the efficacy of antihypertensive treatment with Atacand in hypertensive patients.
- Trial name
- NCT00837720
- Volunteers
- 750 people
- Sponsor
- AstraZeneca
Hypertension
OBPM_Meds2023: Multicentric Prospective Clinical Study to Evaluate the Aktiia Optical Blood Pressure Monitoring (OBPM) Device Compared to Standard Home Blood Pressure Monitoring (HBPM) in Hypertensive Patients When Blood Pressure Lowering Medications Intake
Study design: Prospective, multicentric, randomized, comparative study Study duration: between 4 and 19 weeks depending on the study group.
- Trial name
- OBPM_Meds2023 (NCT05780710)
- Testing
- Aktiia Optical Blood Pressure Monitoring (OBPM) device and antihypertensive drugs (monotherapy and bitherapy), Aktiia Optical Blood Pressure Monitoring (OBPM) device and antihypertensive drugs (monotherapy), Aktiia Optical Blood Pressure Monitoring (OBPM) device and individualized antihypertensive treatment
- Where
- 3 sites in Switzerland
- Volunteers
- 35 people
- Sponsor
- Aktiia SA
Hypertension, Pulmonary
This Study Tests the Safety of Inhaled BAY1237592, How the Drug is Tolerated and How it Effects Patients With High Blood Pressure in the Arteries of the Lungs in the Two Different Disease Groups Pulmonary Arterial Hypertension (PAH) and Chronic Thromboembolic Pulmonary Hypertension (CTEPH)
In this trial the effects of the inhaled drug BAY1237592 will be studied in patients with high blood pressure in the pulmonary blood vessels due to Pulmonary Arterial Hypertension (PAH) and due to Chronic Thromboembolic Pulmonary…
- Trial name
- ATMOS (NCT03754660)
- Testing
- BAY1237592
- Where
- 8 sites in Austria, Czechia and 2 more
- Volunteers
- 38 people
- Sponsor
- Bayer
Hypertension, Type 2 Diabetes
Comparison of Eprosartan/HCT Versus Enalapril/HCT in Hypertensives With Type II Diabetes
This study is to demonstrate the superiority of combination of eprosartan/HCTZ versus ramipril/HCTZ.
- Trial name
- NCT00160160
- Testing
- eprosartan/HCTZ
- Where
- 63 sites in Canada, Denmark and 7 more
- Volunteers
- 440 people
- Sponsor
- Solvay Pharmaceuticals
Hypertension
Systolic Pressure Efficacy and Safety Trial of Alagebrium (SPECTRA)
This study comprises a 3- to 6-week hydrochlorothiazide run in phase, followed by a 12 week double-blind treatment phase, followed by a 2 week single-blind follow-up hydrochlorothiazide treatment phase.
- Trial name
- NCT00089713
- Testing
- alagebrium chloride (ALT-711)
- Where
- United States
- Volunteers
- 392 people
- Sponsor
- Synvista Therapeutics, Inc
Blood Pressure
A Comparative Clinical Study to Assess the Accuracy of TensorTip MTX, a Non Invasive Device
1. Aim- This study is aimed to access the accuracy of TensorTip MTX device measuring Hemoglobin A1C, Oxygen Concentration and Saturation ,Carbon Dioxide, Blood pH, Hemoglobin, Hematocrit, Red Cells Count, platelets, Blood Urea…
- Trial name
- NCT02766010
- Testing
- TensorTip
- Volunteers
- 48 people
- Sponsor
- Cnoga Medical Ltd.
Hypertension
Phase I Study to Investigate the Effect on the Blood Pressure After Oral Administration of SK3530 and Amlodipine
To assess the pharmacodynamic effects of co-administrated SK3530 (PDE5 inhibitor) and Amlodipine, phase I study in Hypertensive patient was designed.
- Trial name
- NCT00626743
- Where
- 2 sites in South Korea
- Volunteers
- 13 people
- Sponsor
- SK Chemicals Co., Ltd.
Hypertension
Effects of Blood Pressure Reduction on High Sensitivity C-Reactive Protein (hsCRP)
The study compares the efficacy of an aggressive versus a moderate initial antihypertensive regimen to reduce blood pressure in patients with Stage 2 hypertension.
- Trial name
- NCT00154271
- Testing
- Valsartan, Valsartan HCT
- Volunteers
- 1,677 people
- Sponsor
- Novartis
Weight, Blood Pressure
Interactive Web Program and Health Coaching for Prehypertensive Adults
This project will develop and evaluate an interactive blood pressure self-management program for adults with prehypertension. The program will target blood pressure self-monitoring and the five proven lifestyle modifications…
- Trial name
- Prehype (NCT02637063)
- Testing
- BlipHub mobile-web app, BlipHub mobile-web app + health coaching, Usual care
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Oregon Center for Applied Science, Inc.
Hypertension
An Efficacy and Safety Study Evaluating the Fixed-Dose Combination of Candesartan Plus Amlodipine in Participants With Mild/Moderate Essential Hypertension
The purpose of this study is to evaluate the efficacy and safety of TCV-116CCB (candesartan cilexetil and amlodipine besylate fixed-dose combination) in Chinese participants with mild to moderate hypertension who do not reach…
- Trial name
- NCT02969265
- Testing
- Amlodipine, TCV-116CCB
- Where
- 25 sites in China
- Sponsor
- Takeda
Hypertension
Comparison of Sevikar® and the Combination of Perindopril/Amlodipine on Central Blood Pressure
Comparison of the combination of amlodipine with an angiotensin receptor blocker or an angiotensin converting inhibitor, on central arterial blood pressure in patients with hypertension and additional risk factors.
- Trial name
- NCT01101009
- Testing
- Perindopril + amlodipine + if necessary, hydrochlorothiazide, olmesartan/amlodipine + hydrochlorothiazide, if necessary.
- Where
- 15 sites in Spain
- Volunteers
- 486 people
- Sponsor
- Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company
Healthy
Physiologic Effect of Spices Ingestion
Human studies have shown that capsaicin, a compound extracted from chilly peppers, can stimulate certain physiologic functions (for example, energy expenditure, thermogenesis, lipid oxidation, heart rate, etc.).
- Trial name
- NCT02193438
- Testing
- Spices intake
- Where
- Switzerland
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Hypertension, Hypercholesterolemia
Efficacy and Safety of Ezetimibe/Rosuvastatin and Amlodipine Patients With High Blood Pressure and High Cholesterol
The goal of this clinical trial is to test whether one pill that combines ezetimibe, rosuvastatin, and amlodipine can safely lower cholesterol and blood pressure in Korean adults with high blood pressure and high cholesterol.
- Trial name
- NCT07564726
- Testing
- Amlodipine, Ezetimibe/Rosuvastatin
- Where
- 21 sites in South Korea
- Volunteers
- 163 people
- Sponsor
- Celltrion Pharm, Inc.
Hypertension
A Study to Evaluate the Effect of LCZ696 on Aortic Stiffness in Subjects With Hypertension
This was the first evaluation of the effects of LCZ696 on local and regional measures of aortic stiffness in subjects with mild to moderate hypertension and widened pulse pressure.
- Trial name
- NCT01870739
- Testing
- sacubitril/valsartan (LCZ696), olmesartan, Amlodipine (Optional)
- Where
- 4 sites in Germany, Switzerland and 1 more
- Volunteers
- 115 people
- Sponsor
- Novartis Pharmaceuticals
Hypertension
Management of Newly Diagnosed and Uncontrolled Hypertension With Fixed-Dose Combination of Perindopril/Amlodipine and Perindopril/Indapamide/Amlodipine
PRECIOUS Study aims to evaluate the efficacy and safety of therapy with fixed-dose combination (FDC) of perindopril/amlodipine (Amlessa®) and FDC of perindopril/indapamide/amlodipine (Co-Amlessa®) on blood pressure reduction in…
- Trial name
- PRECIOUS (NCT03738761)
- Testing
- Amlessa®, Co-Amlessa®
- Where
- 34 sites in Armenia, Croatia and 5 more
- Volunteers
- 471 people
- Sponsor
- KRKA