Clinical trials: Blood Pressures
Dyslipidemia, Hypertension
A Multi-Risk Factor Strategy vs a Guideline-Based Approach in Achieving Blood Pressure and Lipid Goals in Hypertensives at Extra Risk
The purpose of this study is to investigate whether an aggressive multi-risk factor management strategy (Caduet plus therapeutic lifestyle changes (TLC) regimen) will result in greater percentage of patients achieving blood…
- Trial name
- TOGETHER (NCT00412113)
- Testing
- Amlodipine besylate, Amlodipine besylate/atorvastatin calcium single pill combination
- Where
- 51 sites in United States
- Volunteers
- 245 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Hypertension, Metabolic Disorder
A 52 Week Study to Evaluate the Effects of Losartan With or Without HCTZ on Plasma Glucose, Metabolic Parameters, Blood Pressure in Hypertensive Patients With Metabolic Syndrome (0954A-331)
To determine if a one year treatment Losartan with or without HCTZ at different dosages have an effect on metabolic parameters in patients with hypertension and the metabolic syndrome.
- Trial name
- NCT00546052
- Testing
- losartan potassium (+) hydrochlorothiazide
- Volunteers
- 1,738 people
- Sponsor
- Organon and Co
Mild to Moderate Hypertension
A Study to Evaluate Zilebesiran in Japanese Patients With Mild to Moderate Hypertension
The purpose of this study is to evaluate the safety, tolerability, efficacy, pharmacodynamics (PD) and pharmacokinetics (PK) of zilebesiran in Japanese patients with mild to moderate hypertension.
- Trial name
- NCT06423352
- Testing
- Zilebesiran
- Where
- 3 sites in Japan
- Volunteers
- 36 people
- Sponsor
- Alnylam Pharmaceuticals
Subarachnoid Hemorrhage
Study of Changes in CSF Ionic Composition After Aneurysmal Meningeal Hemorrhage
Hyponatremia is a frequent complication of subarachnoid hemorrhage (SAH) with a prevalence of 30 to 50% in patients with this condition.
- Trial name
- ION_SAH (NCT05942755)
- Testing
- Concurrent evaluation of blood and CSF ionograms to determine if there is a correlation between CSF change and the development of hyoponatremia between day 0 and day 14.
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Hospices Civils de Lyon
Blood Pressure
SIMPLifying Elements of Standardized Automated Office Blood Pressure Measurements (Pilot Study)
This study aims to assess whether removing single elements of the standardized office BP measurement procedure will affect the accuracy towards the mean awake ambulatory BP.
- Trial name
- SIMPLE-AOBP (NCT06317168)
- Testing
- Mean awake ambulatory BP measurements
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Hypertension
Controlling and Lowering Blood Pressure With The MOBIUS HD™ (CALM-FIM_EUR)
To evaluate the safety and performance of the MobiusHD system in subjects with resistant hypertension.
- Trial name
- CALM-FIM_EUR (NCT01911897)
- Testing
- MobiusHD
- Where
- 6 sites in Germany, Netherlands
- Volunteers
- 30 people
- Sponsor
- Vascular Dynamics, Inc.
Diet, Healthy, Pregnancy
Hearty Meals for Mom- Pilot Study of Meal Delivery for Cardiometabolic Health During Pregnancy
This study is being done to assess the feasibility, acceptability, and preliminary impact of a meal delivery intervention designed to improve diet quality and promote appropriate gestational weight gain among predominantly Black…
- Trial name
- NCT05512247
- Testing
- Meal Delivery
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Alabama at Birmingham
Intracerebral Hemorrhage
The Intracerebral Hemorrhage Acutely Decreasing Arterial Pressure Trial II
The vast majority of intracerebral hemorrhage (ICH) patients present with elevated blood pressure(BP). Management of BP is controversial with two competing rationales.
- Trial name
- ICH-ADAPT II (NCT02281838)
- Testing
- labetalol/hydralazine/enalapril
- Where
- 2 sites in Canada
- Volunteers
- 142 people
- Sponsor
- University of Alberta
Diabetes, Hypertension
The Produce Drop: Using Food as Medicine to Lower A1C Levels and Blood Pressure
Hypertension and diabetes, which are increasing in prevalence, contribute to significant morbidity and mortality in the U.S. Self-management of these diseases, including adherence to dietary guidelines such as daily fruit and…
- Conditions
- Diabetes, Hypertension, Nutrition Poor
- Trial name
- NCT04421755
- Testing
- Produce delivery, Cooking classes
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- University of Oklahoma
Hypertension, Cardiovascular Disease
Effects of Nitrate in Vegetables on Blood Pressure in Subjects With Prehypertension
The purpose of this study is to examine the effect of different vegetables on cardiovascular function in subjects with moderately increased blood pressure.
- Trial name
- DINO (NCT02916615)
- Testing
- High nitrate vegetables, Low nitrate vegetables + nitrate, Low nitrate vegetables
- Where
- Sweden
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Healthy Volunteers, Nitric Oxide
Evaluation of Adding Nitrate Into Foods for Regulating Nitric Oxide Bioavailability in Healthy Individuals
Inorganic nitrate, found in leafy green vegetables and beetroot, can help lower blood pressure and support heart health. Early experimental work has suggested that dietary nitrate supplementation, in the form of beetroot juice or…
- Conditions
- Healthy Volunteers, Nitric Oxide, Vascular Function
- Trial name
- NCT07172425
- Testing
- Inorganic potassium nitrate-fortified biscuits supplementation, Inorganic potassium nitrate-fortified cereal bar supplementation, Inorganic potassium nitrate-fortified porridge supplementation
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Living Kidney Donation
The Living Kidney Donor Safety Study
The main goal of this study is to understand the long-term effects of kidney donation on blood pressure, kidney function, and patient-reported health-related quality of life.
- Trial name
- LKD (NCT00936078)
- Where
- 13 sites in Australia, Canada
- Volunteers
- 1,438 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Hypertension
Relationship of Urine Sodium Excretion to Central Blood Pressure and Aortic Pulse Wave Velocity
One interesting area is the relationship of high salt intake and central aortic blood pressure. High salt intake is associated development of hypertension and cardiovascular mortality.
- Trial name
- NCT01237717
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- DongGuk University
Serum Lactate Post-pancreatic Duodenectomy
Intra-operative Hypotension and Post-operative Lactate Level After Pancreatic-duodenectomy
Intraoperative hypotension is a frequent occurrence during pancreaticoduodenectomy (PD) and has been associated with impaired tissue perfusion and organ dysfunction.
- Trial name
- HYPOL (NCT07346274)
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Istituto Clinico Humanitas
Hypertension, Prehypertension
Mindfulness-Based Blood Pressure Reduction: Stage 2a RCT
The primary aim is to evaluate impacts of a behavioral intervention called "Mindfulness-Based Blood Pressure Reduction" (MB-BP) vs.
- Trial name
- MB-BP (NCT03256890)
- Testing
- MB-BP Intervention, Enhanced Usual Care Control
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Brown University
Hypertension
Effects of Smartphone Use and Television Viewing on Standardized BP Measurement: The SCREENS-BP Study
The SCREENS-BP study is a randomized crossover study evaluating the effects of smartphone use and television viewing on blood pressure (BP) measurements in 96 adults.
- Trial name
- SCREENS-BP (NCT07903779)
- Testing
- Standardized office blood pressure measurements
- Where
- 2 sites in Australia, Canada
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Healthy, Hypertension
A Validation Study of Selfie Technology for Assessment of Vital Signs
The aim of this study is to compare accuracy of DocMe, a video technology developed by DocMe Health Technologies, with previously validated medical devices used for measurements of heart rate, heart rate variability, respiratory…
- Trial name
- NCT05117762
- Where
- United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- DocMe Technologies Ltd
Fluid Responsiveness
Study About Predicting Fluid Responsiveness in Children Undergoing Neurosurgery
The purpose of this study is to evaluate static and dynamic parameters, echocardiographic parameters, and pleth variability index for predicting fluid responsiveness in children.
- Trial name
- NCT01364103
- Testing
- volume expansion
- Where
- 2 sites in South Korea
- Volunteers
- 33 people
- Sponsor
- Seoul National University Hospital
Blood Pressure
Larsen & Toubro (L&T) Noninvasive Blood Pressure Module Performance Validation
To validate accuracy of the readings of noninvasive blood pressure (NIBP) module with sphygmomanometer as per the requirements of AAMI SP10:2002. This study is for adult and pediatric population.
- Trial name
- NCT01097603
- Volunteers
- healthy volunteers welcome
- Sponsor
- Larsen & Toubro Limited
Portal Blood Pressure, Liver Surgery
Optimization of Hepatic Hemodynamics During Liver Surgery
The purpose of this study is to determine if vasopressin and nitroglycerin in combination will affect hepatic hemodynamics, in the setting of liver surgery.
- Conditions
- Portal Blood Pressure, Liver Surgery, Hepatic Hemodynamics
- Trial name
- NCT02993640
- Testing
- vasopressin + nitro
- Volunteers
- 13 people
- Sponsor
- Sahlgrenska University Hospital
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