Clinical trials: Blood Pressures
Hypertension
Lowering Blood Pressure in Primary Care in Vienna
The aim of this prospective, randomised, open-label, multicentre clinical trial is to enhance blood pressure control in primary care by introducing a standardised and simplified titration regime with single pill combinations…
- Trial name
- Low BP Vienna (NCT02377661)
- Testing
- Olmesartan medoxomil, amlodipine, hydrochlorothiazide
- Where
- Austria
- Volunteers
- 229 people
- Sponsor
- Wilhelminenspital Vienna
Unruptured Intracranial Aneurysms
Acetylsalicylic Acid Plus Intensive Blood Pressure Treatment in Patients With Unruptured Intracranial Aneurysms
Purpose of this study is to assess the hypothesis that a strategy with acetylsalicylic acid (ASA) 100 mg/day, intensive blood pressure treatment (targeted systolic blood pressure below 120 mmHg), and a blood pressure measuring…
- Trial name
- PROTECT-U (NCT03063541)
- Testing
- Acetylsalicylic acid, intensive blood pressure control
- Where
- 18 sites in Germany, Netherlands
- Volunteers
- 776 people
- Sponsor
- Universitätsmedizin Mannheim
Chronic Kidney Disease
L-arginine to Reduce Sympathetic Nerve Activity in CKD Patients
Chronic kidney disease (CKD) is associated with a higher risk of cardiovascular disease and death. An overactive sympathetic nervous system in CKD patients is one of the major mechanisms increasing the cardiovascular risks in…
- Trial name
- NCT03982160
- Testing
- L-Arginine
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- The University of Texas at Arlington
Blood Pressure, Vascular Function
Smartphone App-guided Inspiratory Muscle Strength Training for Lowering Systolic Blood Pressure
This clinical trial aims to assess the efficacy of inspiratory muscle strength training (IMST) guided by a smartphone app vs. IMST delivered in a clinical research setting for lowering systolic blood pressure in adults 18 years…
- Conditions
- Blood Pressure, Vascular Function, Adherence, Treatment
- Trial name
- NCT06229873
- Testing
- App-Based Inspiratory Muscle Strength Training, Clinic-Based Inspiratory Muscle Strength Training
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Hypertension
Calcium Channel Blockers (CCBs) or Diuretics as an Add-on to Olmesartan Medoxomil in Hypertension
The purpose of the study is to test the efficacy and safety of the combination of Calcium Channel Blockers (CCBs)(of the dihydropyridine class) or Diuretics (of the thiazide class) and olmesartan medoxomil in essential…
- Trial name
- NCT00858702
- Testing
- olmesartan medoxomil and a CCB, olmesartan medoxomil and a diuretic
- Where
- Japan
- Volunteers
- 105 people
- Sponsor
- Daiichi Sankyo Co., Ltd.
Primary Hypertension
The Effectiveness of "MaRiTensi" in Increasing Self-Care and Blood Pressure Control: Randomized Controlled Trial
This study aims to know the effectiveness of "MaRiTensi" in improving knowledge, motivation, efficacy, self-care and blood pressure control for hypertension patients.
- Trial name
- "MaRiTensi" (NCT06049862)
- Testing
- MaRiTensi App
- Where
- 3 sites in Indonesia
- Volunteers
- 99 people
- Sponsor
- Chatarina Setya Widyastuti
Restless Legs Syndrome (RLS)
Effect of Rotigotine Patch Treatment on Cardiovascular Markers in Idiopathic Restless Legs Syndrome
Several studies report association between restless legs syndrome (RLS), HTA and cardiovascular diseases . The mechanisms involved in this relationship remained unknown, but several evidences favor the role of periodic limb…
- Trial name
- NCT01823770
- Testing
- Rotigotine
- Where
- France
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Kidney Transplantation
Impact of Arterial Stiffness and Central Aortic Blood Pressure on Kidney Transplant Outcomes
People with CKD have higher prevalence of cardiovascular disease. The mechanism behind this increased risk is complex but there is strong evidence that changes in arterial stiffness play a central role.
- Trial name
- NCT02000869
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Louisiana State University Health Sciences Center Shreveport
Type 2 Diabetes, High Blood Pressure
Polypill for Prevention of Cardiomyopathy
This study will investigate the utility of a polypill-based strategy for patients with type 2 diabetes mellitus and high risk of heart failure (HF), as assessed via the WATCH-DM risk score.
- Trial name
- PolyPreventHF (NCT06143566)
- Testing
- Polypill, Combined prescription of the individual medications
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Texas Southwestern Medical Center
Hypertension
Hypertensive Treatment Pattern Survey for Type II Diabetes Mellitus Patients With Complication and Hypertension
This study will address the treatment rate and control rate of hypertension, treatment pattern and factors to affect blood pressure control by examining (retrospective) medical records of Type II DM patients with DM related…
- Trial name
- CRYSTAL-CO (NCT00771069)
- Where
- 13 sites in South Korea
- Volunteers
- 2,000 people
- Sponsor
- AstraZeneca
Cardiac Output, Hemodynamic Monitoring
Caretaker in the Cardiovascular Intensive Care Unit (CVICU)
To monitor the cardiac post-op patient population with both the pulmonary artery catheter (PAC) and the Caretaker monitor, which will seek to validate the Caretaker monitor against continuous CO via the PAC.
- Trial name
- NCT05779683
- Testing
- Caretaker Device placement
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Wake Forest University Health Sciences
Hypertension
Health Belief Model-Based Telenursing for Hypertension
This randomized controlled trial evaluated the effects of a Health Belief Model-based telenursing intervention on self-efficacy, quality of life, blood pressure, body mass index, and health behaviors in individuals with…
- Trial name
- NCT07823257
- Testing
- Health Belief Model-Based Telenursing Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Marmara University
Pre-hypertension
Personalized Blood Pressure Care Using IoMTs and Artificial Intelligence
In this RCT, up to 100 adults classified as pre-hypertensive will be randomized to either an artificial intelligence (AI) based lifestyle intervention group or an active control group with a 1 to 1 ratio.
- Trial name
- NCT04543656
- Testing
- AI-Based Lifestyle Recommendations, No Lifestyle Recommendations
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Hypertension
A Bengali Dietary Salt Study to Control Blood Pressure
The aim of this study is to assess the benefits of using low-salt and healthy eating educational programme, designed specifically for Bangladeshi kidney patients, compared to the usual diet advice given by the clinic dietitians.
- Trial name
- NCT00702312
- Testing
- Low-salt educational programme, Low-salt Bangladeshi educational programme
- Where
- United Kingdom
- Volunteers
- 56 people
- Sponsor
- Barts & The London NHS Trust
Hypertension
The Effect of Sodium Nitrite on Renal Function and Blood Pressure in Hypertensive Versus Healthy Subjects
The purpose of this study is to investigate how the effect of infused sodium nitrite differs in hypertensives compared to healthy age and sex matched controls.
- Trial name
- HYCA (NCT02527837)
- Testing
- Sodium nitrite, Sodium chloride
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Erling Bjerregaard Pedersen
Hypertension, Cardiovascular Diseases
Cardiovascular Disease Risk Factors in Chinese American Immigrants
The Chinese population is currently the fastest growing ethnic group in New York City (NYC). Research has shown that Chinese immigrants living in NYC have higher rates of cardiovascular disease (CVD) than individuals in China.
- Conditions
- Hypertension, Cardiovascular Diseases, Diabetes Mellitus, Metabolic Syndrome X
- Trial name
- CHA-CHA (NCT00362128)
- Where
- United States
- Volunteers
- 2,072 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Obesity
Safety and Efficacy of Low Doses of V24343 in Obese Subjects
Randomised, double-blind, parallel group comparison of four dose levels of V24343 and placebo to study the effect of V24343 on blood pressure and weight in obese subjects.
- Trial name
- NCT00734201
- Testing
- V24343
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Vernalis (R&D) Ltd
Hypertension
Treatment of Hypertension in Primary Care in Spain
Non-interventional,observational and retrospective study assessing the therapeutic and diagnostic attitude followed in primary care for a hypertensive patient depending on his degree of blood pressure control.
- Trial name
- TAPAS (NCT00868881)
- Where
- 167 sites in Spain
- Volunteers
- 2,160 people
- Sponsor
- AstraZeneca
Hypotension
Intraoperative Systemic Arterial Hypotension Secondary to Beach Positioning
This study aims at describing the systemic arterial hypotension secondary to intraoperative beach chair positioning. This is a non-interventional prospective study.
- Trial name
- HypoTAShoulder (NCT03451565)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Strasbourg, France
Cardiovascular Diseases, Heart Diseases
Birth Weight Effect on Blood Pressure in Late Childhood
To investigate the relationship of birth weight and childhood blood pressure.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension
- Trial name
- NCT00006322
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
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