Clinical trials: Blood Pressures
Hypertension
A Safety Evaluation of ECG Intervals and Blood Pressure in Normal Healthy Volunteers After Use of Nebivolol, Atenolol, Moxifloxacin, or Placebo
Nebivolol is one of a class of drugs known as beta-blockers. These drugs are useful in the treatment of high blood pressure, angina, abnormal heart rhythms and following a heart attack.
- Trial name
- NCT00158093
- Testing
- Nebivolol, Atenolol, Moxifloxacin
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Mylan Bertek Pharmaceuticals
Hypertension
Efficacy and Safety Study of Azilsartan Medoxomil Compared to Ramipril for Treating Essential Hypertension
The purpose of this study is to determine the efficacy and safety of azilsartan medoxomil, once daily (QD), compared to ramipril for treating Essential Hypertension.
- Trial name
- NCT00760214
- Testing
- Azilsartan medoxomil, Ramipril
- Where
- 72 sites in Bulgaria, Estonia and 8 more
- Volunteers
- 885 people
- Sponsor
- Takeda
High Blood Pressure
Heart and Blood Pressure Study: The Effect of Aortic Impedance on Myocardial Relaxation
Does dilation of blood vessels (vasodilation), which decreases aortic stiffness, have a greater effect on heart myocardium relaxation (diastole) than vasodilation which affects mean pressure equally without improving aortic…
- Trial name
- NCT00204984
- Testing
- oral hydralazine and intravenous nesiritide
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Blood Pressure, Hypertension
Effect of Dietary Salt Reduction on Blood Pressure in Kidney Transplant Recipients
Cardiovascular morbidity and mortality is increased in kidney transplant patients. High blood pressure (BP) contributes significantly to this risk and is also associated with shortened allograft survival.
- Conditions
- Blood Pressure, Hypertension, Kidney Transplant; Complications, Dietary Modification
- Trial name
- NCT03373500
- Testing
- Dietary salt reduction
- Where
- United Kingdom
- Volunteers
- 66 people
- Sponsor
- Epsom and St Helier University Hospitals NHS Trust
Hepatorenal Syndrome
The Effect of Terlipressin in the Prevention of Type 2 Hepatorenal Syndrome by Improving Mean Arterial Pressure
Appreciation of the central role for arterial vasodilatation in the pathogenesis of hepatorenal syndrome (HRS) has led to routine use of vasoconstrictors in combination with albumin as a medical therapy for HRS.
- Trial name
- NCT02489864
- Testing
- Terlipressin
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Sun Yat-sen University
Healthy Volunteer
coMparison Between invAsive and Non-invasive assessmenT on Blood Pressure and Cardiac Function in HealthY Participants
This is a cross-sectional cohort study which aims to compare the invasive and non-invasive assessments on aortic blood pressure and cardiac funtion in subjects without history of cardio-vascular disease.
- Trial name
- MATCHY (NCT03372616)
- Testing
- Invasive left ventricular diastolic function assessment, Invasive aortic blood pressure measurement, Non-Invasive left ventricular diastolic function assessment
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shanghai 10th People's Hospital
Sepsis, Norepinephrine
Cerebral Pulsatility Index Compared To Mean Arterial Blood Pressure Guided Protocol In Sepsis Induced Encephalopathy:
The aim of our study is to compare between transcranial doppler pulsatility index and mean arterial blood pressure in guiding management of sepsis induced encephalopathy.
- Conditions
- Sepsis, Norepinephrine, Encephalopathy
- Trial name
- NCT05842616
- Testing
- Transcranial doppler pulsatility index guided protocol, Mean arterial blood pressure guided protocol
- Where
- Egypt
- Volunteers
- 112 people
- Sponsor
- Tanta University
Anaemia
Anemia Study in Chronic Kidney Disease (CKD): Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat-Blood Pressure (ASCEND-BP)
This will be an open-label, randomized, parallel-group study in hemodialysis-dependent (HD) participants with anemia associated with chronic kidney disease (CKD), designed to compare the effects of daprodustat to epoetin alfa on…
- Trial name
- NCT03029247
- Testing
- Daprodustat, Epoetin alfa
- Where
- 11 sites in United States
- Volunteers
- 105 people
- Sponsor
- GlaxoSmithKline
Blood Pressure
Clinical Test Report for Blood Pressure Meter CH-609
Blood pressure meter model CH-609 was to be assessed against the standard mercury sphygmomanometer according to the protocol of the ANSI/AAMI SP-10.
- Trial name
- NCT01044849
- Where
- Taiwan
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Citizen Systems Japan Co., Ltd.
Ocular Physiology, Intraocular Pressure
Effects of Latanoprost on Choroidal Blood Flow Regulation in Human Subjects
Latanoprost is a synthetic prodrug of 17-phenyl-substituted prostaglandin F2α analog. Used at a dose of one drop per day, it has been reported to produce a 30 to 35% reduction in intraocular pressure.
- Conditions
- Ocular Physiology, Intraocular Pressure, Regional Blood Flow
- Trial name
- NCT00712400
- Testing
- Latanoprost 0.005%, Xalatan®
- Where
- Austria
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Medication Adherence, High Blood Pressure
Social Forces to Improve Statin Adherence (Study A)
To assess the effectiveness of reporting statin adherence patterns to a Medication Adherence Partner (MAP) in improving the outcome of statin adherence versus usual care as measured by an electronic pill bottle.
- Conditions
- Medication Adherence, High Blood Pressure, Diabetes
- Trial name
- NCT02018809
- Testing
- Medication Adherence Partner, Electronic pill bottle
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Pennsylvania
Hemodynamic Changes in Pregnancy
Validation of a Non-invasive Hemodynamic Monitor (NexFin) in Pregnant Women
Blood pressure and cardiac output can be measured invasively in pregnant women. Non-invasive monitoring devices are desirable, but until now, no equipment has proven validity.
- Trial name
- NCT01861132
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation
Anesthetized Ventilated Patients
Pulse Transit Time in Anesthetized Patients: Blood Pressure or Cardiac Output as Measured With NICOM Monitor
Pulse transit time (PuTT) - the time between R wave on ECG and initiation of upstroke in the peripheral arterial waveform - described in the previous studies as value that reflects changes in both blood pressure and blood volume.
- Trial name
- PuTT-NICOM (NCT01259687)
- Testing
- Non-invasive cardiac output monitoring
- Where
- 2 sites in Israel
- Volunteers
- 63 people
- Sponsor
- Carmel Medical Center
Blood Pressure Control
Prilocaine for Sphenopalatine Ganglion Block in Endoscopic Hypophysectomy
Patients undergoing endoscopic surgeries for pituitary adenoma excision suffer from wide swings in blood pressure that might increase bleeding and interfere with the surgical field.
- Trial name
- NCT07188987
- Testing
- Sphenopalatine Ganglion Block using 2% lidocaine, Sphenopalatine Ganglion Block
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Kasr El Aini Hospital
Sepsis-Induced Hypotension
A Study of REGN7544 for the Treatment in Adult Patients With Sepsis-Induced Hypotension
This study is researching an experimental drug called REGN7544 (called "study drug"). The study is focused on adult patients (18 to 85 years) hospitalized due to a serious infection (called "sepsis") and receiving…
- Trial name
- ESTELLA (NCT06608901)
- Testing
- REGN7544, PB
- Where
- 29 sites in United States, France
- Volunteers
- 76 people
- Sponsor
- Regeneron Pharmaceuticals
Atrial Fibrillation (AF), Atrial Fibrillation (Paroxysmal)
The Effect of a Digital MediYoga Program on Quality of Life, Blood Pressure and Heart Rate Among Patients With Atrial Fibrillation
Atrial fibrillation (AF) is the most common cardiac arrythmia, associated with increased risk of stroke, heart failure, reduced quality of life (QoL), and psychological distress.
- Conditions
- Atrial Fibrillation (AF), Atrial Fibrillation (Paroxysmal), Quality of Life, Mental Health
- Trial name
- NCT07321964
- Testing
- Yoga 20 minutes, Yoga 60 minutes
- Where
- Denmark
- Volunteers
- 456 people
- Sponsor
- Herlev and Gentofte Hospital
Healthy
Exploratory Study of Circadian Relationships Between Social Behavior, Blood Pressure and Metabolomics
As citizens of the information age, humans leave digital traces of behavior in their communication and movement patterns through our cell phone.
- Trial name
- NCT02249793
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Hypertension
Influence of Sodium Intake on Left Ventricular-arterial Coupling
The objective of the present study is to asses the effectiveness of the aorta-ventricular coupling according to low and high sodium intake in 28 controled hypertensive patients.
- Trial name
- NCT01965236
- Testing
- sodium chloride
- Where
- France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Montpellier
Hypertension, Stroke
TEC4Home Stroke - Feasibility of Home Telemonitoring Technology in Managing Hypertension Among Stroke/TIA Patients
This study will test the feasibility of a home blood pressure telemonitoring (HBPTM) system in patients with minor stroke or TIA in the past year.
- Conditions
- Hypertension, Stroke, Blood Pressure, High, Systolic Hypertension
- Trial name
- NCT03712033
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Vancouver Coastal Health Research Institute
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