Clinical trials: Blood Products
Acute Myeloid Leukemia
Economic Analysis of Blood Product Transfusions According to the Treatment of Acute Myeloid Leukaemia in the Elderly
Blood transfusion requirement represents one of the most significant cost driver associated with acute myeloid leukemia (AML). In addition to an increase prevalence of co morbidities in older patients, AML in older patients is…
- Trial name
- NCT02845232
- Testing
- Transfusion
- Where
- France
- Volunteers
- 214 people
- Sponsor
- Hospices Civils de Lyon
Ventricular Septal Defect
Bypass Clear Priming VSD Cardiopulmonary Bypass Circuit Reduce Bypass Associated Inflammation?
The purpose of this trial is to study if priming the pump used during cardiac surgery with non-blood fluids instead of donated blood products reduces the inflammation that occurs after heart surgery.
- Trial name
- NCT07393243
- Testing
- Clear priming of the bypass pump
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Seattle Children's Hospital
Myelodysplastic Syndrome
Revisiting the Universal Donor: Does Exposure to O Blood Products Affect Patient Outcomes?
In a recent analysis of a large transfusion database (Transfusion Research Utilization, Surveillance and Tracking database [TRUST]), the investigators found that the transfusion of ABO non-identical RBCs to group A individual was…
- Trial name
- UD (NCT04859218)
- Testing
- RBC transfusion
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- McMaster University
Healthy Ageing
Effect of Polyphenol-rich Cocoa Products on Cognitive Function
This project aims to investigate whether consumption of cocoa polyphenols has an impact on cognitive function in individuals aged 50 to 60 years of age and if such an improvement is a result of an improvement in risk factors…
- Trial name
- NCT02996578
- Testing
- polyphenol rich chocolate bar, polyphenol rich cocoa powder, low polyphenol content chocolate bar
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Queen Margaret University
Exanguination, Trauma Coagulopathy
Stability of Blood Clotting Products Stored in Emergency Ambulances Under Real-World Conditions
Emergency medical service (EMS) vehicles are exposed to a wide range of environmental conditions, including high temperatures during summer months.
- Trial name
- STABLE-EMS (NCT07646964)
- Where
- Austria
- Volunteers
- 2 people
- Sponsor
- Medical University of Graz
Liver Cirrhosis, Coagulation Disorder
Thromboelastographic Guide for Blood Products in Cirrhotics
Blood products are commonly used before invasive procedures in patients with end-stage liver diseases despite cirrhosis being a thrombophylic state.
- Trial name
- NCT02362178
- Testing
- Thromboelastography to guide blood products infusion, Standard of care coagulation tests to guide blood products infusion
- Volunteers
- 60 people
- Sponsor
- University of Modena and Reggio Emilia
Grain-Like Products, Postprandial Glucose
Postprandial Glucose, Insulin and Subjective Saturation Response in Healthy Individuals
This study is a pioneering study in which the effect of the consumption of cakes produced with the addition of cereal-like products such as chia and flax seeds, which have high soluble fiber content, on blood glucose and insulin…
- Conditions
- Grain-Like Products, Postprandial Glucose, Plasma Insulin, Subjective Saturation Response
- Trial name
- NCT05358561
- Testing
- Flaxseed and Chia
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Toros University
Trauma Coagulopathy
Viscoelastic Tests (VET) Versus Conventional Coagulation Tests (CCT) for Management of Trauma-Induced Coagulopathy
Traumatic coagulopathy is a complex, multifactorial event that occurs in 20-30% of patients on admission. It increases mortality, and its treatment is one of the main priorities in the early management of severely injured…
- Trial name
- VISCOTAC (NCT06820879)
- Testing
- Viscoelastic Tests (ROTEM)
- Where
- 7 sites in France
- Volunteers
- 316 people
- Sponsor
- Hospices Civils de Lyon
Cirrhosis, Coagulopathy
Comparison of Blood Product Use and Bleeding Events During and After Endoscopic or Neurosurgical Procedures in Patients With Cirrhosis and Coagulopathy
A prospective, randomized clinical trial comparing blood product use and bleeding events during and after endoscopic or neurosurgical procedures in patients with cirrhosis and coagulopathy: Rotational Thromboelastometry (ROTEM)…
- Trial name
- SCARLET (NCT02457403)
- Testing
- ROTEM, Conventional Therapy
- Volunteers
- 68 people
- Sponsor
- Ohio State University
Blood Glucose, High, Metabolic Disease
Functional and Value-Added Dairy Products and Blood Glucose Control
Milk proteins possess multiple biological activities including their effect on blood glucose control, satiety and energy intake.
- Conditions
- Blood Glucose, High, Metabolic Disease, Overweight and Obesity
- Trial name
- NCT05400694
- Testing
- Food
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mount Saint Vincent University
Nicotine Dependence, Cigarettes
Acute Oral Effects of Heated Tobacco Products
Heated tobacco products (HTP) are devices which heat, but not burn tobacco. They do not produce cigarette smoke but rather an aerosol. HTPs are marketed as less harmful alternatives to smoking.
- Trial name
- NCT05538702
- Testing
- IQOS 3.0 DOU with bland taste unit (Heated Tobacco Product), IQOS 3.0 DUO with menthol taste unit (Heated Tobacco Product), Marlboro Gold (Conventional cigarette)
- Where
- Hungary
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Hemorrhage
Transfusion and Coagulation Management in Trauma Patients After the Introduction of a Coagulation Algorithm
Comparison of the consumption of blood and coagulation products (packed red blood cells, fresh frozen plasma, platelet concentrates, fibrinogen, coagulation factor concentrates, coagulation factor XIII, activated factor VII, van…
- Trial name
- NCT02569606
- Where
- 2 sites in Switzerland
- Volunteers
- 1,800 people
- Sponsor
- Donat R. Spahn
Cirrhosis, Liver
Rotational Thromboelastometry (ROTEM™) Guided Transfusion for Elective Procedures in Patients With Cirrhosis (REduCe): An Open Label Randomized Controlled Trial.
REDuCe is designed to evaluate the role of ROTEM™ in determining the need and the amount of pre-emptive blood products use in patients with cirrhosis undergoing elective procedures compared to the current standard of care.
- Trial name
- REduCe (NCT05698134)
- Testing
- ROTEM, Standard of care
- Where
- Singapore
- Volunteers
- 74 people
- Sponsor
- Changi General Hospital
Levels of DHA in the Blood
The Effects of Study Products Containing Varying Quantities of Docosahexaenoic Acid (DHA)
The clinical trial will provide a milk-based drink with constant amounts of nutrients but differing amount of Docosahexaenoic Acid (DHA).
- Trial name
- NCT01174134
- Testing
- Nutritional beverage
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mead Johnson Nutrition
Postoperative Hemorrhage, Blood Transfusion
Femoral Blood Gas and Prediction of Postoperative Bleeding
Postoperative bleeding is still an important concern after major abdominal surgery. Postoperative bleeding is the most important determinant of morbidity and death.
- Trial name
- NCT06285656
- Volunteers
- 100 people
- Sponsor
- Ankara City Hospital Bilkent
Hyperlipidemias
Effect of ANKASCIN 568-P Products Regulating Blood Lipid
This study is a randomized, double-blind, placebo-controlled, parallel-controlled trial (24 weeks in total), divided into three periods (screening, treatment, and discontinuation follow-up)
- Trial name
- NCT05737355
- Testing
- ANKASCIN 568-P Red yeast rice capsules
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- SunWay Biotech Co., LTD.
Hypertriglyceridemia
Changes in Blood Lipids After Long-term Consumption of n-3 LC-PUFA-Enriched Dairy Products
The study was performed to investigate the effects of n-3 LC-PUFA supplemented dairy products cardiovascular risk factors in hypertriglyceridemic patients.
- Trial name
- NCT00639041
- Testing
- n-3 LC-PUFA
- Where
- Germany
- Volunteers
- 51 people
- Sponsor
- University of Jena
Blood Glucose
Blood Glucose Response of Novel Wild Rice Enhanced Food Products (Trial 1)
The goal of this acute double-blind cross over trial is to test the effects of a wild rice cake product compared to products currently on the market on glycaemic control. The main questions it aims to answer are: 1.
- Trial name
- ABWE (NCT06497972)
- Testing
- White bread (control, 32 grams, 14.4 grams of carbohydrate), Brown rice cake, Wild rice (25%) and brown rice (75%) cake
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Dylan MacKay
Cirrhosis, Liver, Coagulopathy
Thromboelastography Guided Blood Product Transfusion for Upper Gastrointestinal Bleeding in Cirrhosis
The goal of this clinical trial is to compare resuscitation strategies in patients with cirrhosis and gastrointestinal bleeding.
- Conditions
- Cirrhosis, Liver, Coagulopathy, GastroIntestinal Bleeding
- Trial name
- STRATEGIC (NCT05583539)
- Testing
- Thromboelastography
- Sponsor
- Vanderbilt University Medical Center
Hemophilia A
Prospective, Non-interventional Study to Evaluate the Effectiveness of Elocta Compared to Conventional Factor Products
The purpose of the study is to evaluate the effectiveness of Elocta compared to conventional factor products in the prophylactic treatment of patients with haemophilia A over a 24-month prospective period.
- Trial name
- NCT02976753
- Testing
- efmoroctocog alfa, Factor VIII
- Where
- 36 sites in Austria, Belgium and 7 more
- Volunteers
- 361 people
- Sponsor
- Swedish Orphan Biovitrum