Clinical trials: Blood Products
Cardiovascular Diseases
Use of the Quantra QPlus Sytem in Cardiac Surgery
Single center retrospective study evaluating the impact of using the Quantra QPlus System to guide transfusion decisions on postoperative outcomes in patients undergoing cardiac surgery.
- Trial name
- NCT05501730
- Testing
- Quantra QPlus System
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- HemoSonics LLC
Patient Blood Management, Blood Product Transfusion for All Conditions
Patient Blood Management in Obstetrics
Obstetric anemia and hemorrhage are major causes of maternal morbidity and increased healthcare utilization. Although red blood cell (RBC) transfusion is commonly used, it is associated with higher rates of postpartum…
- Trial name
- PBM (NCT07544017)
- Where
- United Arab Emirates
- Volunteers
- 44,000 people
- Sponsor
- Corniche Hospital
Blood Loss Anemia, Extracorporeal Membrane Oxygenation Complication
Red Blood Cell Transfusion in ECMO - A Feasibility Trial
Extracorporeal Membrane Oxygenation (ECMO) is an invasive and resource intense treatment used to support critically ill patients who have suffered severe cardiac arrest, cardiac failure or respiratory failure (including severe…
- Conditions
- Blood Loss Anemia, Extracorporeal Membrane Oxygenation Complication, Disability Physical, Cognitive Ability, General
- Trial name
- ROSETTA (NCT05814094)
- Testing
- Red Blood Cell Transfusion
- Where
- 2 sites in Australia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Complement Mediated Bacterial Killing in Healthy Adults
Complement 2: Blood Donations to Develop Vaccines Against Infectious Diseases
We need human blood to understand the immune response to infection and to test promising new vaccines against infectious diseases in the laboratory.
- Trial name
- C2 (NCT01945307)
- Where
- United Kingdom
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Blood Glucose
Blood Glucose Response of Novel Wild Rice Enhanced Food Products (Trial 1)
The goal of this acute double-blind cross over trial is to test the effects of a wild rice cake product compared to products currently on the market on glycaemic control. The main questions it aims to answer are: 1.
- Trial name
- ABWE (NCT06497972)
- Testing
- White bread (control, 32 grams, 14.4 grams of carbohydrate), Brown rice cake, Wild rice (25%) and brown rice (75%) cake
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Dylan MacKay
Healthy
A Study to Learn How Different Products of the Study Medicine Called PF-07940367 Are Taken up Into the Blood in Healthy Adults
The purpose of this study is to compare two finished products of PF-07940367 in terms of the uptake into the blood stream. This study is seeking participants who are: Healthy male or female participants aged 18 years or older.
- Trial name
- NCT06190561
- Testing
- PF-07940367
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pfizer
Obstetric Anesthesia Problems, Placenta Accreta
Fibrinogen Concentrate and Placenta Acreta Spectrum
The aim of this study is to evaluate the relationship between fibrinogen use and bleeding in patients who underwent cesarean section with a prediagnosis of PAS.
- Trial name
- NCT05938062
- Testing
- the group without fibrinogen concentrate (GNF) , the group with fibrinogen concentrate (GF)
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Thrombocytopenia
Safety and Performance of MIRASOL® PRT Treated Platelet Transfusion Products
The primary objective of the study is to measure platelet corrected count increments and the incidence of serious adverse events (SAE).
- Trial name
- NCT00263809
- Testing
- Pathogen Reduction Technology
- Where
- 10 sites in France
- Volunteers
- 118 people
- Sponsor
- Terumo BCTbio
Mastectomy
Application Of Autologous Blood Products During Modified Radical Mastectomy
The purpose of this study is to determine if the application of autologous (your own blood) blood products during mastectomy improves wound healing and decreases complications following surgery compared to mastectomy without the…
- Trial name
- NCT00802477
- Testing
- Application of autologous blood products., Standard Modified Radical Mastectomy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Marshall University
Healthy, Overweight and Obesity
The Impact of Citrus Products on Cardiovascular Health
Epidemiological studies have indicated that the consumption of citrus fruit is inversely associated with the risk of cardiovascular disease.
- Trial name
- NCT03611114
- Testing
- Blood orange juice, Control drink
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Induced Pluripotent Stem Cells
Blood Collection From Healthy Volunteers and Patients for the Production of Clinical Grade Induced Pluripotent Stem Cell (iPSC) Products
Background: Pluripotent stem cells are cells that can be converted to any type of cell (muscle, nerve, liver, etc.). Researchers are collecting blood samples to develop way to make a special cell product called induced…
- Trial name
- NCT02056613
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Sarcoma, Kaposi, HIV Infections
A Study of Ro 24-7429 in Patients With HIV-Related Kaposi's Sarcoma
To study the effects of Ro 24-7429 on tumor growth in patients with HIV-related Kaposi's sarcoma. To study the safety and tolerance, effects on HIV replication, and immunologic effects of Ro 24-7429 in this patient population.
- Trial name
- NCT00002314
- Testing
- Ro 24-7429
- Where
- 2 sites in United States
- Sponsor
- Hoffmann-La Roche
Hemorrhage
Transfusion and Coagulation Management in Trauma Patients After the Introduction of a Coagulation Algorithm
Comparison of the consumption of blood and coagulation products (packed red blood cells, fresh frozen plasma, platelet concentrates, fibrinogen, coagulation factor concentrates, coagulation factor XIII, activated factor VII, van…
- Trial name
- NCT02569606
- Where
- 2 sites in Switzerland
- Volunteers
- 1,800 people
- Sponsor
- Donat R. Spahn
Diabetes Prevention, Obesity Prevention
Fluid Dairy Products Consumed Before and Within a Pizza Meal on Glycemic Response, Food Intake and Satiety in Children
The purpose of this study is to examine the effects of fluid dairy products on blood glucose and insulin, satiety and energy intake in normal weight and overweight/obese children in the age range of 9-14 y.
- Trial name
- NCT02147496
- Testing
- Dietary Intervention
- Where
- Canada
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Hemophilia B
Post Marketing Study in Haemophilia B Patients Using Nonafact® (Human Coagulation Factor IX)
In this postmarketing study, the safety of Nonafact® (human coagulation factor IX) is evaluated in previous treated and untreated patients with severe, moderate or mild haemophilia B.
- Trial name
- NCT00139828
- Testing
- human coagulation Factor IX
- Where
- 7 sites in Netherlands
- Volunteers
- 12 people
- Sponsor
- Prothya Biosolutions
Cardiovascular Disease
Study of the Impact of Trans Fatty Acids From Dairy Products on Cardiovascular Risk Factors
The majority of trans fatty acids consumed by the general population is derived from products that have been formulated using significant amount of hydrogenated vegetable oil (the so-called industrial trans fat).
- Trial name
- TRANS (NCT01163175)
- Testing
- Ruminant trans fats
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Laval University
Blood Glucose, High, Metabolic Disease
Functional and Value-Added Dairy Products and Blood Glucose Control
Milk proteins possess multiple biological activities including their effect on blood glucose control, satiety and energy intake.
- Conditions
- Blood Glucose, High, Metabolic Disease, Overweight and Obesity
- Trial name
- NCT05400694
- Testing
- Food
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mount Saint Vincent University
Cardiovascular Disease
A Study Examining Effects of Apples/ Apple Products on Heart Disease Risk
This study will examine if health benefits of consuming nutrient-rich apples, an apple extract and freeze dried apple product will be similar.
- Trial name
- APPS (NCT01585519)
- Testing
- High/ Low Epicatechin Apples/ Apple Extract/ Granules
- Where
- 2 sites in United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Diabetes Prevention, Obesity Prevention
PERFECT Project - Part 2 - Study 3
The objectives are to test the acute effects of different bagels containing pulse ingredients on: 1) aerobic endurance and substrate oxidation during exercise 2) response of blood glucose, insulin and appetite to an aerobic…
- Trial name
- NCT02365363
- Testing
- Control, Pea flour, Pea fibre
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Hemophilia A
Prospective, Non-interventional Study to Evaluate the Effectiveness of Elocta Compared to Conventional Factor Products
The purpose of the study is to evaluate the effectiveness of Elocta compared to conventional factor products in the prophylactic treatment of patients with haemophilia A over a 24-month prospective period.
- Trial name
- NCT02976753
- Testing
- efmoroctocog alfa, Factor VIII
- Where
- 36 sites in Austria, Belgium and 7 more
- Volunteers
- 361 people
- Sponsor
- Swedish Orphan Biovitrum