Clinical trials: Blood Sugar; High
Hyperglycemia, Postprandial
Evaluation of OxxyneaGS in Acute Glycemic Regulation on Light Hyperglycemic Subjects
This study aims to evaluate and select the best combination of polyphenol and white kidney bean ingredients in the acute glycemic modulation after a complete meal by measuring blood glucose and insulin.
- Trial name
- NCT04914416
- Testing
- Verum T1, Verum T2, Verum T3
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Fytexia
Type 2 Diabetes, Pre Diabetes
Multi-morbidity Screening in People With Type 2 Diabetes and Pre Diabetes
People with type 2 diabetes are at risk of complications linked with high blood sugars and these are monitored for in healthcare appointments.
- Conditions
- Type 2 Diabetes, Pre Diabetes, Obstructive Sleep Apnea, Non-Alcoholic Fatty Liver Disease
- Trial name
- NCT06053177
- Where
- United Kingdom
- Volunteers
- 400 people
- Sponsor
- University of Liverpool
Nephrotic Syndrome
Steroid Diabetes in Patients With Kidney Disease
If steroid diabetes is not recognized in time, it will cause irreversible damage to the body. Nephropathy patients are more likely to have steroid diabetes ,the incidence rate up to 25%,due to hypoalbuminemia, high-dose hormone…
- Trial name
- NCT06161701
- Testing
- no intervention
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Zhejiang Provincial People's Hospital
Prediabetic State, Glucose Intolerance
Impact of Sorghum Rice on Beta-Cell Function and Insulin Resistance in Prediabetes
Prediabetes is a condition where blood sugar levels are higher than normal but not yet high enough to be diagnosed as diabetes. Without lifestyle changes, people with prediabetes often develop type 2 diabetes, a serious disease…
- Conditions
- Prediabetic State, Glucose Intolerance, Insulin Resistance, Obesity and Overweight
- Trial name
- NCT07298304
- Testing
- Sorghum Rice, white rice
- Where
- Indonesia
- Volunteers
- 26 people
- Sponsor
- Dr. Soetomo General Hospital
Diabetes Mellitus, Type 2, Pre Diabetes
Resistant Starch, Gut Bacteria and Diabetes
The aim of the study is to investigate, if resistant starch type III increases butyrate-producing bacteria in the gut of (pre-) diabetic subjects. Diabetic blood parameters are also of interest.
- Trial name
- RSDD (NCT03057444)
- Testing
- SymbioIntest
- Where
- Germany
- Volunteers
- 13 people
- Sponsor
- University of Hohenheim
Stable Coronary Artery Disease, Obesity
Chronic Inflammatory Activation in Fat Tissue: an Atherogenic Factor in Stable Coronary Artery Disease
Chronic inflammatory activation in fat tissue can be the link between adiposity and an increased risk for atherosclerosis. Aim of the study is to investigate how molecular alterations in fat tissue can be influenced by regular…
- Conditions
- Stable Coronary Artery Disease, Obesity, Impaired Glucose Tolerance
- Trial name
- KFO (NCT00510588)
- Testing
- training, training + metformin, training + glitazon
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- University of Leipzig
Septic Shock, Adverse Event
Early Versus Conventional Cessation of Hydrocortisone in Septic Shock
Septic shock is one of the causes of death in ICU and hospital. Refractory shock is the problem which healthcare providers should recognize though it is difficult to handle with.
- Conditions
- Septic Shock, Adverse Event, Hydrocortisone, Hyperglycemia
- Trial name
- CESSHYDRO (NCT05818826)
- Testing
- normal saline solution, Hydrocortisone and normal saline solution
- Where
- Thailand
- Volunteers
- 160 people
- Sponsor
- Mahidol University
Prediabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
Personalized Meal Timing and Walking Based on Glucose Patterns in Adults With Prediabetes
This study will test whether glucose sensor data can be used to identify the time of day when adults with prediabetes are most likely to have high blood sugar after meals.
- Conditions
- Prediabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Prediabetes or Diabetes
- Trial name
- CLOCK-PRIME (NCT07618663)
- Testing
- Phenotype-Guided Meal Timing and Postprandial Walking, Sleep Hygiene and Step-Count Advice
- Where
- Pakistan
- Volunteers
- 105 people
- Sponsor
- Shifa International Hospital
Pre Diabetes
BRInging the Diabetes Prevention Program to GEriatric Populations
Over 24 million Americans are over 65 years and have prediabetes. Prediabetes can be addressed using a public health approach: among the 20% of participants in the Diabetes Prevention Program (DPP) who were ages 60 and over, the…
- Trial name
- BRIDGE (NCT05166785)
- Testing
- DPP Tailored for Older Adults and delivered via Telehealth, In-Person Diabetes Prevention Program (DPP)
- Where
- United States
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Severe Hyperglycemia, Postoperative Infection
Intraoperative Hyperglycemia and Infections After Orthopedic Surgery
Postoperative infections are a common complication. A relationship between perioperative severe hyperglycemia and postoperative infections has been found in patients undergoing craniotomy.
- Conditions
- Severe Hyperglycemia, Postoperative Infection, Orthopedic Patients
- Trial name
- NCT03903354
- Testing
- Incidence of infections within 7 days postoperatively
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- Federico Bilotta
Diabetes Mellitus and Heart Failure
A Dose Finding Study to Assess the Effect of LIK066 Compared to Placebo or Empagliflozin in Patients With Type 2 Diabetes Mellitus and Heart Failure
This was a dose-finding study to evaluate the efficacy, safety and tolerability of 3 different doses of LIK066 compared to placebo or empagliflozin in T2DM patients with heart failure
- Trial name
- NCT03152552
- Testing
- LIK066, Empagliflozin
- Where
- 106 sites in United States, Argentina and 22 more
- Volunteers
- 125 people
- Sponsor
- Novartis Pharmaceuticals
Type 2 Diabetes, Pre-diabetes
Curcumin Therapy in Patients With Impaired Glucose Tolerance and Insulin Resistance
The incidence rate of type 2 diabetes in Thai populations is high and increasing every year. Cardiovascular disease is the main complication of this disease, which has been defined as an important cause of death among Diabetic…
- Conditions
- Type 2 Diabetes, Pre-diabetes, Insulin Resistance, Cardiovascular Risk
- Trial name
- NCT01052025
- Testing
- Curcumin
- Where
- Thailand
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Srinakharinwirot University
Sleep Apnea, Pre-diabetes
Mechanisms of Prediabetic States in Sleep Apnea
The purpose of this study is to better understand how sleep apnea contributes to the development of diabetes.
- Trial name
- NCT04234217
- Testing
- Continuous positive airway pressure, Niacin
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Chicago
Cardiovascular Risk Factor
Short Term Ketone Supplementation and Cardiometabolic Health
The purpose of this research study is to determine if short-term consumption of a dietary ketone drink, which increases the blood circulation concentrations of beta-hydroxybutyrate, a ketone, affects blood vessel health and…
- Trial name
- NCT04236388
- Testing
- Ketone drink
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Obesity, Metabolic Syndrome X
Drug Therapy Induced Weight Loss to Improve Blood Vessel Function in Subjects With Obesity
Obesity is common (>30% of US adults), contributes to substantial morbidity and mortality, but is difficult to treat. Partly this is due to the transient, arduous and modest nature of lifestyle interventions.
- Trial name
- REVIVE (NCT01351753)
- Testing
- Metformin, Orlistat, Topiramate
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- University of Iowa
Prediabetes
Effect of Saxagliptin on Pre-Diabetes Mellitus and Obesity
The purpose of the study is to examine the effect of Saxagliptin in the newly diagnosed people with pre-diabetes and obesity besides lifestyle intervention ,there to evaluate DPP 4 inhibitors of reversing pre-diabetes curative…
- Trial name
- NCT01960205
- Testing
- Saxagliptin, metformin, lifestyle intervention
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Shandong Provincial Hospital
GDM
Effect of Early Lifestyle Intervention on Perinatal Outcomes in High-risk Women for Gestational Hyperglycemia
This study aims to explore whether early intervention for high-risk groups of gestational hyperglycemia can improve insulin resistance and effectively prevent the occurrence of GDM, and evaluate which pathophysiological subtypes…
- Trial name
- NCT07141173
- Testing
- Individual lifestyle management
- Where
- China
- Volunteers
- 604 people, healthy volunteers welcome
- Sponsor
- Tianjin Central Hospital of Gynecology Obstetrics
Overweight, Pregnancy
A Low Glycemic Load Diet During Pregnancy in Overweight Women
This study will compare the effects of a low glycemic load versus standard diet for pregnancy on outcomes related to risk for obesity, diabetes, and heart disease in both mother and infant.
- Trial name
- NCT00364403
- Testing
- Low glycemic load, Low fat diet
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Boston Children's Hospital
Diabetes, Impaired Glucose Tolerance
Liquid Protein Preloads With Different Carbohydrate Types Effects on the Glycaemic and Insulinaemic Response
This study hypothesizes that milk protein consumed together or shortly before a white rice or white bread carbohydrate meal exerts different influence on the glycaemic, insulinaemic responses.
- Conditions
- Diabetes, Impaired Glucose Tolerance, Obesity
- Trial name
- NCT02151188
- Testing
- Bread, Soy milk and cow milk, real-time ultrasonography (GE LOGIQ P5 ultrasound in CNRC)
- Where
- Singapore
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
Pre Diabetes, Impaired Glucose Tolerance
Efficacy and Safety of 12-weeks Supplementation of Eubacterium Hallii on Insulin Sensitivity and Glycaemic Control
This 12 week placebo-controlled study evaluates the efficacy and safety of E. hallii supplementation.
- Conditions
- Pre Diabetes, Impaired Glucose Tolerance, Insulin Sensitivity, Insulin Resistance
- Trial name
- NCT04529473
- Testing
- Eubacterium hallii
- Where
- 3 sites in United States, Ireland and 1 more
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Atlantia Food Clinical Trials