Clinical trials: Blood Sugar (Glucose) Control
Efficacy, Safety
A Trial Investigating the Effect of 4 Weeks Dosing of XEN-D0501 on Blood Glucose Reduction in Patients With Diabetes
This is a randomised, double-blind, placebo-controlled, parallel-group trial investigating the effect of 4 weeks bi-daily dosing of XEN-D0501 on blood glucose reduction as add-on to metformin in patients with diabetes mellitus…
- Conditions
- Efficacy, Safety, Pharmacokinetics, Diabetes Mellitus, Type 2
- Trial name
- NCT05353686
- Testing
- XEN-D0501
- Where
- 10 sites in Lithuania
- Volunteers
- 54 people
- Sponsor
- Pila Pharma
Diabetes, Diabetes Mellitus, Type 2
Effect of Liraglutide on Blood Glucose Control in Japanese Subjects With Type 2 Diabetes
This trial is conducted in Japan. The aim of this research trial is to evaluate the effect of treatment with liraglutide or placebo on blood glucose control after 14 weeks in Japanese subjects with type 2 diabetes.
- Trial name
- NCT00154414
- Testing
- liraglutide
- Where
- Japan
- Volunteers
- 226 people
- Sponsor
- Novo Nordisk A/S
Type 2 Diabetes Treated With Insulin
Steno2tech - Continuous Glucose Monitoring and Type 2 Diabetes.
The overall objective of this research study is to examine the effectiveness of the use of CGM vs. SMBG in persons with insulin-treated type 2 diabetes on glycemic variables and patient reported outcomes on treatment…
- Trial name
- NCT04331444
- Testing
- CGM, training course, Peer-support
- Where
- Denmark
- Volunteers
- 96 people
- Sponsor
- Steno Diabetes Center Copenhagen
Healthy
Comparison of Dietary Fats on Vascular Parameters
The purpose of the study is to examine the effect of consuming 50g of fat from 5 different sources (coconut, canola, grapeseed, chia, and butter) on arterial stiffness, blood pressure and blood glucose levels.
- Trial name
- COIL (NCT01876394)
- Testing
- Coconut Oil, Canola Oil, Grapeseed Oil
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Diabetes, Diabetes Mellitus, Type 2
Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes
This trial is conducted in Europe. The trial is designed to show the effect of treatment with liraglutide or placebo on blood glucose control after 14 weeks in subjects with type 2 diabetes.
- Trial name
- NCT00154401
- Testing
- liraglutide
- Where
- 39 sites in Denmark, France and 2 more
- Volunteers
- 177 people
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus, Type 2
A Research Study to See How a New Weekly Insulin, Insulin Icodec When Given Along With Semaglutide Helps in Reducing the Blood Sugar Level in Patients With Type 2 Diabetes
This study looks at how a new medicine insulin icodec helps in reducing blood sugar levels when given along with semaglutide in patients with type 2 diabetes.
- Trial name
- NCT05813912
- Testing
- Insulin Icodec, Semaglutide
- Where
- 39 sites in Czechia, Malaysia and 3 more
- Volunteers
- 148 people
- Sponsor
- Novo Nordisk A/S
Blood Glucose
Blood Glucose Response of Novel Wild Rice Enhanced Food Products (Trial 2)
The goal of this acute double-blind cross over trial to test the effects of different wild rice cereal products compared to products currently on the market on glycaemic control. The main questions it aims to answer are: 1.
- Trial name
- ABWE (NCT06498024)
- Testing
- Kellogg's - rice krispies (control), Kellogg's - rice krispies (control) + 125ml milk, Novel cereal (40% Canadian wild rice, 60% fava bean blend) + 125 ml milk
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Dylan MacKay
Health Adult Subjects
Dihydroberberine Effects on Body Composition and Metabolic Health in Healthy Adults
The goal of this clinical trial is to evaluate whether dihydroberberine (DHB) supplementation can improve body composition, blood sugar control, energy levels, appetite, and mood in healthy adults with overweight or mild obesity.
- Trial name
- DHB (NCT07322679)
- Testing
- Dihydroberberine（DHB）
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Nanjing Nutrabuilding Bio-tech Co., Ltd.
Diabetes Mellitus, Type 1
Efficacy Study on the Control of Blood Glucose Concentration in Type 1 Diabetic Patients
·Main objective: To compare the variability of fasting capillary blood glucose concentration, observed with insulin glargine combined with insulin glulisine and with insulin detemir combined with insulin glulisine, in type 1…
- Trial name
- VARIABILITE (NCT00271284)
- Testing
- insulin glulisine / insulin glargine, insulin glulisin / insulin detemir
- Where
- France
- Volunteers
- 88 people
- Sponsor
- Sanofi
Type 2 Diabetes Mellitus
A Research Study to See How Well CagriSema Compared to Semaglutide, Cagrilintide and Placebo Lowers Blood Sugar and Body Weight in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor
The study will look at how well CagriSema helps people lower their blood sugar and body weight. CagriSema is a new weekly medicine that combines two medicines called semaglutide and cagrilintide.
- Trial name
- REIMAGINE 2 (NCT06065540)
- Testing
- Cagrilintide, Semaglutide
- Where
- 405 sites in United States, Argentina and 30 more
- Volunteers
- 2,734 people
- Sponsor
- Novo Nordisk A/S
Critical Illness
Blood Glucose Control With A Software-Algorithm In Intensive Care Unit (ICU) Patients
Hyperglycemia is common in critically ill patients and associated with an adverse outcome. Recently, large randomized controlled trials have demonstrated that tight glycaemic control (TGC) reduces morbidity and mortality in this…
- Trial name
- Aldea _01 (NCT00735163)
- Testing
- enhanced model predictive control algorithm (eMPC)
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- B. Braun Melsungen AG
Type 2 Diabetes Mellitus (T2DM)
A Phase III Clinical Study to Evaluate the Efficacy and Safety of GZR18 Injection in Subjects With Type 2 Diabetes Mellitus and Poor Blood Glucose Control by Diet and Exercise
The main purpose of this study is to investigate the Efficacy and Safety of GZR18 Injection in Chinese Subjects with Type 2 Diabetes Mellitus and Poor Blood Glucose Control by Diet and Exercise
- Trial name
- Optimum 1 (NCT06777238)
- Testing
- GZR18
- Where
- China
- Volunteers
- 274 people
- Sponsor
- Gan & Lee Pharmaceuticals.
Diabetes, Diabetes Mellitus, Type 2
Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes
This trial is conducted in Japan. The trial aims for comparison of the effect on glycaemic control of liraglutide, compared to sulfonylurea (SU treatment), as assessed by HbA1c after 24 and 52 weeks in subjects with type 2…
- Trial name
- NCT00393718
- Testing
- liraglutide, glibenclamide
- Where
- Japan
- Volunteers
- 400 people
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus, Type 2
Glucose Monitoring Comparison in Primary Care
This research trial will randomize 50 primary care clinics and 354 patients in accordance with their primary care clinic assignment to 2 different glucose monitoring strategies (SMBG vs.
- Trial name
- GluCoCare (NCT05222815)
- Testing
- CGM, SMBG
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- HealthPartners Institute
Type 2 Diabetes Mellitus
The Effects of Pilates on Functional Capacity and Blood Glucose Levels in Adults With Diabetes Type 2
The aim of this study is to investigate the effects of the Pilates training on Functional Capacity among adults with type 2 diabetes The aim of this study is to investigate the effects of the Pilates training on blood glucose…
- Trial name
- NCT05261776
- Testing
- pilates exercise, brisk walk
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Diabetes, Diabetes Mellitus, Type 2
Effect of Insulin Detemir and Insulin Glargine on Blood Glucose Control in Subjects With Type 2 Diabetes
This trial is conducted in Asia, South America and the United States of America (USA). The aim of this clinical trial is to determine whether two insulin treatments given once daily are equally effective with respect to the blood…
- Trial name
- EFFICACY (NCT00909480)
- Testing
- insulin detemir, insulin glargine
- Where
- 88 sites in United States, Argentina and 4 more
- Volunteers
- 457 people
- Sponsor
- Novo Nordisk A/S
Hyperglycemia
Fat Based Enteral Nutrition for Blood Glucose Control in ICU
In this randomized, double-blind clinical trial, eligible hospitalized ICU patients with EN will be included. Patients will be divided into two groups.
- Trial name
- NCT02584907
- Testing
- High Fat Enteral Nutrition
- Where
- Iran
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University
Hyperglycemia
Pilot Study to Evaluate a Method of Controlling High Blood Sugar in the Pediatric Intensive Care Unit
Recent studies of adult intensive care unit (ICU) patients have shown significantly decreased morbidity and mortality when blood sugar concentrations are closely controlled.
- Trial name
- NCT00240149
- Testing
- Regular Insulin via Insulin-Glucose Algorithm
- Where
- 2 sites in United States
- Sponsor
- Stanford University
Type 2 Diabetes
Glargine U300 Hospital Trial
The purpose of this study is to find out if treatment with Glargine U300 when compared to Glargine U100 will result in similar sugar control in patients with Type 2 Diabetes (T2D), who are admitted to the hospital and then…
- Trial name
- NCT03013985
- Testing
- Glargine U300, Glargine U100, Glulisine Insulin
- Where
- 4 sites in United States
- Volunteers
- 247 people
- Sponsor
- Emory University
Post Bariatric Hypoglycemia
Avexitide for Treatment of Post-Bariatric Hypoglycemia
AVX-001 (LUCIDITY) is a Phase 3 study to evaluate avexitide compared to placebo in participants with post bariatric hypoglycemia (PBH) related to Roux-en-Y gastric bypass (RYGB).
- Trial name
- LUCIDITY (NCT06747468)
- Testing
- Avexitide
- Where
- 21 sites in United States
- Volunteers
- 75 people
- Sponsor
- Amylyx Pharmaceuticals Inc.