Clinical trials: Blood Sugar (Glucose) Control
Type 1 Diabetes
SGLT2 Inhibitor Adjunctive Therapy to Closed Loop Control in Type 1 Diabetes Mellitus
The primary purpose of this study is to evaluate the safety and efficacy of combining SGLT2 inhibitors with closed loop control (CLC).
- Trial name
- CiQ-SGLT2 (NCT04201496)
- Testing
- Empagliflozin + Control-IQ x 4 wks then Basal-IQ x 2 wks, Empagliflozin + Basal-IQ x 2 wks then Control-IQ x 4 wks, No Empagliflozin + Control-IQ x 4 wks then Basal-IQ x 2 wks
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Ananda Basu, MD
Type 2 Diabetes
Lifestyle Intervention in Patients With New Onset Type 2 Diabetes.
The study seeks to establish if weight loss achieved through a program of intensive lifestyle management can result in improvements in GLP-1 and glycaemic control, in patients with newly diagnosed type 2 diabetes mellitus.
- Trial name
- NCT01402388
- Testing
- Group lifestyle programme
- Volunteers
- 22 people
- Sponsor
- The Royal Bournemouth Hospital
Type 1 Diabetes (T1D), Pregnancy
Automated Insulin for Management of Intrapartum Glycemia
The goal of this clinical trial is learn if automated insulin delivery (AID) systems can be used for glucose management during labor/delivery for pregnant people with type 1 diabetes (T1D).
- Conditions
- Type 1 Diabetes (T1D), Pregnancy, Pre-Gestational Diabetes
- Trial name
- AIMING (NCT06883344)
- Testing
- Automated insulin delivery (AID) system, Intravenous (IV) insulin
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- University of California, San Francisco
Type 2 Diabetes Mellitus
Herbal Tea in the Treatment of Type 2 Diabetes Mellitus
Diabetes mellitus is a chronic disease caused by inherited and/or acquired deficiency in production of insulin by the pancreas, or by the ineffectiveness of the insulin produced. It has become a major healthcare problem in India.
- Trial name
- NCT03787563
- Testing
- Herbal Tea
- Where
- India
- Volunteers
- 10 people
- Sponsor
- Composite Interceptive Med Science
Diabetes
Glycated Albumin Monitoring
The goal of this observational study is to learn if the short-term glucose marker (glycated albumin) works as well or better than CGM and/or hemoglobin A1c to indicate to providers that a change in medication is working to…
- Trial name
- NCT07777900
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Washington University School of Medicine
Acute Stroke, Hyperglycemia
SELESTIAL: Trial of Insulin to Control Blood Sugar After Acute Stroke Using Magnetic Resonance Imaging (MRI) End-Points
High blood sugar (hyperglycaemia) affects 40% of acute stroke patients and has a major adverse effect on survival and recovery. Increased production of lactic acid in brain tissue that has a poor blood supply is postulated to be…
- Trial name
- NCT00124826
- Testing
- Insulin
- Where
- United Kingdom
- Volunteers
- 45 people
- Sponsor
- University of Glasgow
Type 2 Diabetes Mellitus, Overweight and Obesity
Study to Assess the Effects and Safety of ZGN-1061 in Overweight and Obese Participants With Type 2 Diabetes
The purpose of this study is to evaluate the efficacy and safety of the study drug ZGN-1061 in participants with type 2 diabetes.
- Trial name
- NCT03254368
- Testing
- ZGN-1061
- Where
- 23 sites in Australia, New Zealand
- Volunteers
- 188 people
- Sponsor
- Zafgen, Inc.
Type 2 Diabetes Mellitus, Obesity
The TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes
This research study is being performed to begin to determine the effectiveness of two dominant bariatric surgery procedures versus an intensive lifestyle intervention to induce weight loss in patients and promote improvements in…
- Trial name
- TRIABETES (NCT01047735)
- Testing
- Roux-en-Y Gastric Bypass Surgery, Laparoscopic Adjustable Gastric Banding, Lifestyle Weight Loss Intervention
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- University of Pittsburgh
Gestational Diabetes
The Effect of a Low Glycemic Index Diet on Blood Sugar Control in Women With Gestational Hyperglycemia
The purpose of the study is to see if a low glycemic index diet will reduce blood sugar levels in pregnant women with high blood sugar levels.
- Trial name
- NCT00314717
- Testing
- Control diet, Low GI diet
- Where
- Canada
- Volunteers
- 47 people
- Sponsor
- University of Toronto
Type 2 Diabetes Mellitus, Chronic Kidney Disease Stage 4
A Study to Evaluate Safety and Effects of Sotagliflozin 400 and 200 mg on Glucose Control in Participants With Type 2 Diabetes, Severe Impairment of Kidney Function and Inadequate Blood Sugar Control
Primary Objective: To demonstrate the superiority of sotagliflozin 400 milligrams (mg) versus placebo with respect to hemoglobin A1c (HbA1c) reduction at Week 26 in participants with Type 2 diabetes who have inadequate glycemic…
- Trial name
- SOTA-CKD4 (NCT03242018)
- Testing
- Sotagliflozin
- Where
- 106 sites in United States, Argentina and 13 more
- Volunteers
- 277 people
- Sponsor
- Lexicon Pharmaceuticals
Diabetes, Diabetes Mellitus, Type 2
Effect of Liraglutide or Glimepiride Added to Metformin on Blood Glucose Control in Subjects With Type 2 Diabetes
This trial is conducted in Asia. The trial is designed to compare the effect on glycaemic control of liraglutide or glimepiride added to metformin in subjects with type 2 diabetes
- Trial name
- NCT00614120
- Testing
- liraglutide, glimepiride, metformin
- Where
- 50 sites in China, India and 1 more
- Volunteers
- 929 people
- Sponsor
- Novo Nordisk A/S
Type 1 Diabetes, Hypoglycemia
CGM Use in Poorly Controlled Youth With Type 1 Diabetes
The purpose of this prospective study is to determine if trial use of a Dexcom G6 CGM system for a 10 day wear period in high risk, poorly controlled pediatric Type 1 diabetes patients increases uptake of personal CGM use, and…
- Conditions
- Type 1 Diabetes, Hypoglycemia, High Blood Sugar
- Trial name
- IMPaCT (NCT04721145)
- Testing
- Dexcom G6 Continuous Glucose Monitor
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Johns Hopkins University
Elevated Blood Glucose
Whole-Food Magnesium for Mental and Cardiometabolic Health
This randomized, double-blind, placebo-controlled clinical trial will evaluate the effects of daily supplementation with E-Z Mg™, a commercially available whole-food-based magnesium supplement, on sleep, mood, fatigue, and…
- Trial name
- NCT07865351
- Testing
- Low-Dose Whole-Food-Based Magnesium Supplement, Moderate-Dose Whole-Food-Based Magnesium Supplement
- Volunteers
- 45 people
- Sponsor
- George Mason University
Gestational Diabetes Mellitus in Pregnancy, Anxiety in Pregnancy
The Effect of Model-Based PMR Training on Anxiety and Blood Sugar Levels to Women With Gestational Diabetes
This research is a randomized controlled experimental study to evaluate the effects of PMR application based on HBM in terms of blood sugar and anxiety levels in women with GDM.
- Trial name
- GDM (NCT05611541)
- Testing
- Diet therapy, Progressive Muscle Relaxation training, Progressive Muscle Relaxation group, The group who received diet therapy and practiced their daily activities.
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ege University
Blood Glucose
Efficacy of a Brown Seaweed Powder for Glycemic Control
The objectives of this trial are to confirm efficacy in human of a brown seaweed powder and explore dose-response relationship by comparing two different doses.
- Trial name
- NCT02853916
- Testing
- 500 mg InSea2®, 250 mg InSea2®
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Type 2 Diabetes
REMIssion of Type 2 Diabetes Between Intermittently Scanned Continuous Glucose Monitoring and Capillary Blood Glucose Monitoring When Added to Low-calorie Meal Replacement and Diabetes Self-management Education
The goal of the study is to evaluate the effectiveness of intermittently scanned continuous glucose monitoring compared to capillary blood glucose monitoring among people with type 2 diabetes initiating low calorie meal…
- Trial name
- REMIT2D isCGM (NCT07157384)
- Testing
- Low calorie meal replacement plan, Diabetes self management education, Intermittently scanned continuous glucose monitoring
- Where
- 6 sites in Canada
- Volunteers
- 176 people
- Sponsor
- LMC Diabetes & Endocrinology Ltd.
Pre-Diabetes
15-minute Individual Consultation to Improve Blood Glucose Control in Pre-diabetes
This research will assess the feasibility of conducting a randomised control trial to evaluate the effectiveness of a 15-minute one-to-one consultation to improve blood glucose control in pre-diabetes.
- Trial name
- NCT03483129
- Testing
- Consultation
- Where
- United Kingdom
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Aberystwyth University
Type 1 Diabetes
Timing of Meal Insulin Boluses for Optimal Postprandial Glycemic Control in Type 1 Diabetes
Blood glucose levels in patients with type 1 diabetes tend to peak after eating a meal due to the delayed action of insulin when compared to carbohydrate absorption from food.
- Trial name
- NCT01693302
- Testing
- Insulin
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Colorado, Denver
Diabetes Mellitus, Type 2, Hypoglycemic Agents
Effects of Vildagliptin Versus Glibenclamide on Glycemia After Exercise in Patients With Type 2 Diabetes
Exercise is considered a way to benefit the health of unhealthy and healthy individuals. This is confirmed by different scientific researches, in which people who participated improve their health.
- Conditions
- Diabetes Mellitus, Type 2, Hypoglycemic Agents, Diabetic Blood Glucose Monitoring, Exercise
- Trial name
- DIABEX-VILDA (NCT01867502)
- Testing
- MET + Vildagliptin Group, MET + Glibenclamide Group
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Diabetes Mellitus
Effect of Polyherbal Compound for Control of Blood Sugar in Impaired Glucose Tolerance and Diabetes
The aim of the study is to control blood sugar with Sugar Balance capsules which is the leaves of three herbs: ivy ground (Coccinia indica)-200mg, bougainvillia (Bougainvillea spectabilis)-30mg, Madagascar periwinkle…
- Trial name
- NCT02866539
- Testing
- Polyherbal capsule coccinia, bougainvillea, catharanthus
- Where
- India
- Volunteers
- 122 people
- Sponsor
- Composite Interceptive Med Science