Clinical trials: Blood Sugar (Glucose) Control
Type II Diabetes Mellitus
Using a Motivational Interviewing (MI) Informed Text Messaging Program to Lower Blood Sugar in Diabetic Patients.
Despite advances in medical therapy for diabetes, significant numbers of patients fail to achieve adequate blood glucose control.
- Trial name
- MI-SMS (NCT02012478)
- Testing
- MI- informed SMS program
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Pennsylvania
Type II Diabetes Mellitus, Renal Insufficiency
A Study to Look at the Effect MEDI0382 Has on Blood Sugar in People With Type 2 Diabetes and Kidney Problems and Also to Check That MEDI0382 is Well Tolerated
A study to look at the effect MEDI0382 has on blood sugar in people with type 2 diabetes and kidney problems and also to check that MEDI0382 is well tolerated.
- Trial name
- NCT03550378
- Testing
- MEDI0382
- Where
- 7 sites in Germany, United Kingdom
- Volunteers
- 41 people
- Sponsor
- MedImmune LLC
Elevated Blood Glucose, Low-carbohydrate Diet
Understanding the Paradoxical Rise in Blood Glucose in the Context of a Low-carbohydrate Diet
The purpose of this project was to elucidate the phenomenon of elevated blood glucose in the context of dietary carbohydrate restriction.
- Trial name
- NCT07713316
- Testing
- Carbohydrate Drink, Fat Drink, Protein Drink
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Brigham Young University
Diabetes, Diabetes Mellitus, Type 2
Effect of Biphasic Insulin Aspart 30 Combined With Metformin on Blood Glucose Control in Subjects With Type 2 Diabetes Inadequately Controlled With Basal Insulin
This trial is conducted in Asia. This single arm trial aims to evaluate the blood glucose control with twice daily biphasic insulin aspart 30 in combination with metformin in Chinese subjects with type 2 diabetes inadequately…
- Trial name
- NCT00669864
- Testing
- biphasic insulin aspart 30, metformin
- Where
- China
- Volunteers
- 293 people
- Sponsor
- Novo Nordisk A/S
Type 1 Diabetes Mellitus
A Trial to Investigate Post Prandial Blood Glucose Control With Fast-acting Human Insulin HinsBet® Compared to Insulin Lispro (Humalog®) and Regular Human Insulin (Huminsulin® Normal) After Ingestion of a Standardized Meal in Subjects With T1DM
This is a 2 centres, randomised, double blind, three-treatment, three-period cross-over trial in subjects with type 1 diabetes mellitus.
- Trial name
- NCT02739906
- Testing
- BioChaperone Human Insulin (HinsBet®), Insulin Lispro (Humalog®), Regular human insulin (Huminsulin® Normal)
- Where
- 2 sites in Germany
- Volunteers
- 36 people
- Sponsor
- Adocia
Healthy
The Glycaemic Index of Manuka Honey
Five high methylglyoxal (460-667 mg/kg) Manuka honey samples were selected from different geographical locales around the North Island of New Zealand and tested for glycaemic index (GI) in 10 healthy volunteers in a…
- Trial name
- NCT01615588
- Testing
- Manuka Honey
- Where
- New Zealand
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Waiariki Institute of Technology
Diabetes Mellitus, Type 2
Glycemic Optimization Treatment Study
To compare the frequency of severe hypoglycemia events for 5 dosing algorithms of Lantus®, each of varying intensity and defined by their end-of -study target for self monitored plasma glucose(SMPG), in patients with Type 2…
- Trial name
- GOT (NCT00552370)
- Testing
- Lantus®
- Volunteers
- 5,062 people
- Sponsor
- Sanofi
Disorder Related to Renal Transplantation
The Effects of Omega-3 Fatty Acids in Renal Transplantation
Omega-3 fatty acids are provided through dietary intake of fish and seafood. Several dietary supplements containing omega-3 fatty acids are also commercially available.
- Trial name
- ORENTRA (NCT01744067)
- Testing
- Omega-3 fatty acids
- Where
- 2 sites in Norway
- Volunteers
- 132 people
- Sponsor
- Oslo University Hospital
Diabetes Mellitus, Type 1
A Clinical Study to Investigate and Compare the Impact of High Protein Pasta, Lower Protein Pasta and White Rice on Blood Sugar Control in People With Type 1 Diabetes Mellitus (T1DM)
The aim of this clinical study is to investigate and compare the postprandial glycemic response to three different meal types rich in carbohydrates, that is, white pasta, high protein pasta and white rice consumed by individuals…
- Trial name
- NCT03362151
- Testing
- Regular pasta, High protein pasta, White rice
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Sansum Diabetes Research Institute
Leukemia, Lymphoma
Effect of Tight Control of Blood Glucose During Hyper-CVAD Chemotherapy For Acute Lymphocytic Leukemia (ALL)
The goal of this clinical research study is to learn if intense management and control of blood sugar levels during treatment for acute lymphocytic leukemia, Burkitts lymphoma, or lymphoblastic lymphoma will result in decreased…
- Trial name
- NCT00500240
- Testing
- Insulin Glargine, Insulin Aspart
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- M.D. Anderson Cancer Center
Subarachnoid Hemorrhage, Intracranial Hemorrhage
Enteral Nutrition and Glycemic Variability Neurological Intensive Care Unit Study
Primary Objective: To determine the effects of a diabetes specific enteral formula compared to a standard formula supplemented with protein (isocaloric and isonitrogenous) on the mean blood glucose and glycemic variability in a…
- Conditions
- Subarachnoid Hemorrhage, Intracranial Hemorrhage, Ischemic Strokes, Subdural Hematoma
- Trial name
- ANUS1014 (NCT01463878)
- Testing
- Glycerna, Jevity - Control Diet
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Eastern Virginia Medical School
Appetitive Behavior, Glucose Metabolism Disorders
Splenda: Effects on Blood Glucose Concentration, Appetite Scores and Subsequent Energy Intake
This study investigates the effects of Splenda, an artificial sweetener powder containing sucralose, on post-prandial blood glucose levels, appetite scores and subsequent energy intake.
- Trial name
- NCT05810337
- Testing
- Splenda drink, Maltodextrin drink, High carbohydrate breakfast
- Where
- United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- King's College London
Diabetes Mellitus, Type 2
Effects of Vitamin D3 and Prebiotics Supplementation on Cardiovascular Risk Factors in Patients With Type 2 Diabetes
The goal of this randomized, double-blind, placebo-controlled, 6-month supplementation study in individuals with type 2 diabetes is to investigate whether taking daily dietary supplements of vitamin D3 (1600 IU) or prebiotics…
- Trial name
- NCT06351566
- Testing
- Vitamin D3, Prebiotics
- Where
- 2 sites in China
- Volunteers
- 190 people
- Sponsor
- Huazhong University of Science and Technology
Type2 Diabetes, Cardiovascular Diseases
Peanuts and Glycemic Control
A two-period randomized crossover study will be conducted to determine the effect of peanuts on glycemic control, and elucidate the role of the microbiome in glucose regulation, in individuals with impaired fasting glucose.
- Trial name
- NCT03654651
- Testing
- Peanut, High carbohydrate snack
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Penn State University
Diabetes
Self-Monitoring of Blood Glucose Study#1: The Ability of People With Diabetes to Use OneTouch(R) Ultrasmart(tm)
Insulin therapy requires monitoring and frequent review of glucose levels to optimize dosing. Effective presentation and data analysis are essential.
- Trial name
- NCT00333853
- Testing
- OneTouch(r) UltraSmart(r)
- Where
- 7 sites in United States
- Volunteers
- 250 people
- Sponsor
- LifeScan
Diabetes Mellitus, Type 2
Using 32 - Gauge Needles With Lengths of 5 mm and 8 mm on Pain Post-injection, Leak and Blood Glucose
This is a Clinical crossover trial study. In this study, 100 patients with type II diabetes will be selected based on entry and exit criteria, then randomly divided into two equal groups (group "A" and group "B").In the first…
- Trial name
- NCT04460092
- Testing
- 5-mm 32-gauge Insulin needles in the first three days of Intervention, 8-mm 32-gauge Insulin needles in the first three days of Intervention, 5-mm 32-gauge Insulin needles in the last three days of Intervention
- Where
- Iran
- Volunteers
- 100 people
- Sponsor
- Baqiyatallah Medical Sciences University
Plasma Glucose Following Prolonged Heat Exposure
Glycemic Control Following Occupational Work in a Hot Environment
Occupational workers regularly perform physically demanding tasks in hot environments, exposing them to heat stress and potential dehydration.
- Trial name
- NCT06982612
- Testing
- Hot environment, Temperate condition
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Type 1 Diabetes Mellitus (T1DM), High Level of Sugar (Glucose) in the Blood
A Phase 3 Study to Evaluate the Safety of Sotagliflozin in Patients With Type 1 Diabetes Who Have Inadequate Glycemic Control With Insulin Therapy Alone
This Phase 3 study was designed to demonstrate the net benefit of sotagliflozin versus placebo in patients with Type 1 Diabetes (T1D).
- Trial name
- inTandem3 (NCT02531035)
- Testing
- Sotagliflozin
- Where
- 135 sites in United States, Argentina and 17 more
- Volunteers
- 1,405 people
- Sponsor
- Lexicon Pharmaceuticals
Dietary Habits
Low-carbohydrate Versus Low-fat Breakfast in Type 2 Diabetes
The prevalence of type 2 diabetes (T2D) is increasing worldwide, with ~380 M currently suffering from this chronic, debilitating disease. T2D is characterized by high blood glucose levels in the mornings and after meals.
- Trial name
- NCT04550468
- Testing
- Low-Carb High-Fat breakfast, Low fat "standard care" control breakfast
- Where
- Canada
- Volunteers
- 127 people
- Sponsor
- University of British Columbia
Diabetes Mellitus, Type 2
Study of Rimonabant/Metformin Combinations to Investigate Diabetes (Blood Sugar) Control in Patients With Type 2 Diabetes
The primary objective of the study is to demonstrate superiority of rimonabant/metformin combinations in Glycosylated Hemoglobin 1c (A1C) reduction over the corresponding single agent metformin and over rimonabant alone in…
- Trial name
- NCT00754689
- Testing
- Rimonabant, Metformin
- Where
- United States
- Sponsor
- Sanofi