Clinical trials: Blood Transfusion Complication
Post-cardiac Surgery, Blood Transfusion Complication
Perioperative Risk Factors of Outcomes for Cardiac Surgery: A Retrospective Study
Based on a review of about 10,000 patients undergoing cardiac surgery under CPB in West China Hospital of Sichuan University and the Second Affiliated Hospital of Zhejiang University, we try to evalute the effect of blood…
- Conditions
- Post-cardiac Surgery, Blood Transfusion Complication, Prognosis
- Trial name
- NCT04980742
- Testing
- acute normovolemic hemodilution
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Post Operative Hemorrhage, Transfusion Related Complication
Monitoring Noninvasively for Infusion and Transfusion Optimization
This is a multicenter, cluster randomized controlled trial to assess the effects of an optimized intraoperative fluid and blood management strategy on postoperative complications.
- Conditions
- Post Operative Hemorrhage, Transfusion Related Complication, Blood Transfusion Associated Adverse Reactions, Hypovolemia
- Trial name
- NCT04388722
- Testing
- Pulse CO-Oximeter Sensor
- Sponsor
- Masimo Corporation
Blood Transfusion Complications
Point-of-Care RBC Washing to Prevent Transfusion-Related Pulmonary Complications
This study is designed to determine if point-of-care washing of allogeneic Leukocyte-Reduced Red Blood Cells reduces pulmonary complications when compared to standard-of-care Leukocyte-Reduced Red Blood Cells in a cardiac…
- Trial name
- NCT02094118
- Testing
- Point-of-care washed red blood cell transfusion., Standard of care red blood cell transfusion.
- Where
- 2 sites in United States
- Volunteers
- 171 people
- Sponsor
- Mayo Clinic
Blood Transfusion Complication, Oxidative Stress
Study the Effect of Blood Transfusion on Oxidant-antioxidant Status in Term and Near-term Neonates
Primary aim is to evaluate the effect of blood transfusion on oxidant-antioxidant status in premature neonates. Secondary aim is to assess the effect of the age of transfused red blood cells on the biological markers of oxidative…
- Trial name
- NCT03767361
- Testing
- packed red blood cells transfusion
- Where
- Egypt
- Volunteers
- 65 people
- Sponsor
- Rania Ali El-Farrash
Liver Transplantation, Postoperative Renal Complication
Postoperative Complications After Liver Transplantation
Incidence and risk factors for renal, cardiovascular and pulmonary complications after liver transplantation are not well defined.
- Conditions
- Liver Transplantation, Postoperative Renal Complication, Postoperative Pulmonary Complication, Postoperative Cardiovascular Complication
- Trial name
- NCT02761109
- Where
- Italy
- Volunteers
- 1,600 people
- Sponsor
- Azienda Ospedaliera S. Maria della Misericordia
Mitral Valve Replacement, Transfusion Reaction
Blood Transfusion Management in Patients With Mitral Valve Replacement in China
The evaluation uses ΔHb as an independent factor combined with artificial intelligence (AI) to predict its impact on the prognosis and blood transfusion of patients undergoing cardiac surgery, thereby guiding perioperative…
- Conditions
- Mitral Valve Replacement, Transfusion Reaction, Blood Transfusion Complication
- Trial name
- NCT03885570
- Testing
- Mitral valve replacement
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Sickle Cell Disease, Pregnancy, High Risk
TAPS2 Transfusion Antenatally in Pregnant Women With SCD
Sickle Cell Disease (SCD) is a serious inherited blood disorder affecting red blood cells. When oxygen levels drop the red cells become abnormally shaped and unable to move through the blood vessels easily.
- Conditions
- Sickle Cell Disease, Pregnancy, High Risk, Blood Transfusion Complication
- Trial name
- TAPS2 (NCT03975894)
- Testing
- Serial prophylactic exchange blood transfusion (SPEBT).
- Where
- 6 sites in United Kingdom
- Volunteers
- 50 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Knee Osteoarthritis, Blood Clot
Oral Tranexamic Acid vs. Oral Aminocaproic Acid to Reduce Blood Loss and Transfusion After Total Knee Replacement.
This study compares two oral medications (tranexamic acid and aminocaproic acid) as hemostatic agent administered in patients undergoing total knee replacement.
- Conditions
- Knee Osteoarthritis, Blood Clot, Transfusion Related Complication, Blood Loss
- Trial name
- NCT03365999
- Testing
- Oral Tranexamic Acid, Oral Aminocaproic Acid
- Where
- Mexico
- Volunteers
- 92 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Blood Transfusion Complication, Wrong Blood in Tube
Proficiency Based Training to Investigate Blood Sampling Errors Including WBIT
The objective of this study is to determine the effectiveness of a Proficiency Based Progression training programme, together with evidence based individual feedback for any residual errors, which has been specifically developed…
- Conditions
- Blood Transfusion Complication, Wrong Blood in Tube, Pre Analytical Blood Sample Errors
- Trial name
- NCT03577561
- Testing
- Proficiency Based Progression Training in Phlebotomy
- Where
- Ireland
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Patrick Henn
Pelvic Fracture, Transfusion Reaction
Blood Transfusion Among Patients With Pelvic Fracture in China
According to the patient's blood management concept, this study intends to collect basic information, surgical data, blood transfusion related data and patient prognosis data of patients with pelvic fractures, and to construct a…
- Conditions
- Pelvic Fracture, Transfusion Reaction, Blood Transfusion Complication
- Trial name
- PBM (NCT03855644)
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Blood Transfusion Complication
To Establish a Blood Transfusion Prediction Model for Liver Transplantation Patients Based on PBM
Based on the principle of patient blood management, this study aims to reduce the risk of blood transfusion in allogeneic liver transplantation patients, to ensure the safety of blood transfusion, and to provide new methods and…
- Trial name
- NCT03814772
- Testing
- Liver transplant
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Blood Transfusion Complication, Necrotizing Enterocolitis
Splanchnic Oxygenation Response to Feeds in Preterm Neonates: Effect of Red Blood Cell Transfusion
Since 1987, red blood cell (RBC) transfusions have been proposed as a potential risk factor for necrotizing enterocolitis (NEC), which is one of the most severe gastrointestinal complications of prematurity.
- Conditions
- Blood Transfusion Complication, Necrotizing Enterocolitis, Enteral Feeding Intolerance, Preterm Infant
- Trial name
- NIRS_RBC (NCT03643458)
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Transfusion Related Complication, Wrong Blood in Tube
Proficiency Based Training to Investigate WBIT
Incorrect labelling of blood samples occurs at a rate of 1% in the general laboratories and 6% in Blood Transfusion Laboratories.
- Trial name
- NCT03476005
- Testing
- proficiency based progression training
- Where
- Ireland
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Patrick Henn
Coagulopathy, Blood Transfusion Complication
Thromboelastography Normal Reference Values in China Hunan Province
The purpose of this study was to establish the normal reference range of Thrombelastogram parameters in Hunan by a multicenter study, and to analyze the specificity of Thrombelastogram detection and the influence of gender, age…
- Trial name
- NCT03146455
- Testing
- no intervention
- Where
- China
- Volunteers
- 498 people, healthy volunteers welcome
- Sponsor
- The Third Xiangya Hospital of Central South University