Clinical trials: Blood Volume
Obesity
Effect of Oral Feeding on Gastric Emptying, Gut Blood Flow, and Hormone Responses in Obese and Healthy Weight Subjects
Obesity is a complicated condition that is poorly understood. The aim of this study is to increase our knowledge of how the condition may arise, and what makes obese people remain obese.
- Trial name
- NCT03860623
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Human Immunodeficiency Virus (HIV), Cardiovascular Risk Factor
Reducing Systemic Inflammation in People on Antiretroviral Therapy
This randomized, open-label clinical trial will evaluate whether adding fostemsavir to current antiretroviral therapy can reduce the risk of cardiovascular disease in people with well-controlled HIV.
- Trial name
- RESTART (NCT07030920)
- Testing
- Fostemsavir
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Hernia, Inguinal
Effects of Using Divided Mesh and Using a Non Divided Mesh on Testicular Blood Flow and Volume in Laparoscopic Hernia Repair
Laparoscopic inguinal hernia repair techniques has been compared with the open techniques in several studies. However, no one studied about the different uses of the same type of mesh on the same surgical technique, and effects…
- Trial name
- NCT03421925
- Testing
- Laparoscopic totally extraperitoneal procedure for inguinal hernia
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Okan University
Aortic Aneurysm
Patient Tailored Contrast Volume for Preoperative CT Angiography of the Aorta
An in-house calculator was developed to calculate the appropriate contrast dose, rather than standardly administering a 120ml dose.
- Trial name
- NCT05716568
- Testing
- Contrast dose reduction, CT-angiography
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
End-Stage Renal Disease, Hemodialysis
Hemocontrol and Blood Pressure Control in Dialysis Patients
Volume overload contributes significantly to the pathogenesis of hypertension in hemodialysis patients. The Hemocontrol(HC)system (Gambro), which automatically adjusts ultrafiltration rate and dialysate conductivity according to…
- Trial name
- NCT00319774
- Testing
- Hemocontrol Biofeedback System
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Université de Montréal
Severe Anaemia
Study of Safe Blood Transfusion Volumes to Correct Acute Severe Anaemia
Greater volume of whole blood(30mls/kg compared to 20mls/kg) following standard calculations, given to children with severe anaemia will be beneficial in haematological correction and can be given safely since respiratory…
- Trial name
- Tx30 (NCT01461590)
- Testing
- Whole blood
- Where
- 2 sites in Uganda
- Volunteers
- 160 people
- Sponsor
- Prof Kathryn Maitland
Respiratory Aspiration, Hyperglycemia
Maltodextrin Versus Sugar Water Carbohydrate Loading and Gastric Volume in Geriatric Lower Limb Orthopedic Surgery
Before surgery, patients are asked to fast so the stomach is empty and stomach contents cannot enter the lungs during anesthesia. Long fasting is uncomfortable and can raise blood sugar and stress responses in older adults.
- Conditions
- Respiratory Aspiration, Hyperglycemia, Inflammation
- Trial name
- CHO-GERIGAS (NCT07872683)
- Testing
- Maltodextrin carbohydrate drink, Sugar water
- Where
- Indonesia
- Volunteers
- 62 people
- Sponsor
- Udayana University
Pulmonary Hypertension (PH), End Stage Kidney Disease (ESRD)
Euvolemia-Based Assessment of Pulmonary Hypertension in Stable Hemodialysis Patients
Pulmonary hypertension (PH) is a frequent and clinically significant complication in patients with end-stage kidney disease (ESKD) undergoing maintenance hemodialysis (HD).
- Conditions
- Pulmonary Hypertension (PH), End Stage Kidney Disease (ESRD), Hemodialysis Patients, Volume Overload
- Trial name
- EU-PHASE-HD (NCT07676786)
- Testing
- Observational Assessment
- Where
- 2 sites in Romania
- Volunteers
- 30 people
- Sponsor
- Stefan Lujinschi
Neuropathic Pain
Comparison of Pain-Related Changes in Cerebral Blood Volume in Burn Patients With Neuropathic Pain
The investigators will observe increased or decreased CBV in patients with thermal injury compared with the CBV in healthy controls.
- Trial name
- NCT04125576
- Testing
- magnetic resonance imaging(MRI)
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hangang Sacred Heart Hospital
Cerebrovascular Circulation
Blood Brain Flow and Exercise
Cerebral vasodilator responses to CO2 will be measured in young healthy adults, healthy sedentary older adults, and healthy exercise trained older adults.
- Trial name
- NCT02653638
- Testing
- Control, Indomethacin
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Ideal Sample Volume for Blood Cultures
Finding Ideal Blood Culture Volume in NICU
The investigators want to assess the effectivity of different sample volumes in blood cultures.
- Trial name
- NCT02468947
- Where
- Israel
- Volunteers
- 800 people
- Sponsor
- Shaare Zedek Medical Center
Cardiac Surgery
Low Tidal Volume Ventilation With Hyperoxia Avoidance During Cardiopulmonary Bypass (The FOCUS Trial)
This is a multi-institutional study (CCF, UPMC, OSU) evaluating different ventilation strategies during cardiopulmonary bypass on mortality and postoperative pulmonary complications, with sub-study investigating…
- Trial name
- NCT04978636
- Testing
- Continuous low-tidal volume ventilation with using FiO2 of 0.21, Continuous low tidal volume ventilation with using FiO2 of 1.0, Apnea During CPB
- Where
- United States
- Volunteers
- 5,502 people
- Sponsor
- The Cleveland Clinic
Bladder Cancer
Effect of SVV Guided Fluid Therapy on Blood Loss and Postoperative Outcomes
The purpose of this study is to investigate the effect of stroke volume variation (SVV) guided fluid therapy on the blood loss and postoperative outcomes in radical cystectomy.
- Trial name
- NCT02373735
- Testing
- crystalloid, colloid, mannitol
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Asan Medical Center
Multiple Sclerosis
MR Perfusion Imaging and Hypercapnia (Increased Carbon Dioxide) to Study New Blood Vessel Formation in Multiple Sclerosis
This study will use magnetic resonance imaging (MRI) to examine and compare changes in blood flow and blood volume in the brains of normal volunteers and patients with multiple sclerosis (MS).
- Trial name
- NCT00064909
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Heart Failure
Monitoring Outpatient Blood VolumE in Heart Failure
In patients discharged following heart failure treatment, the consistency of blood volume status and components over time is unknown.
- Trial name
- MOVE-HF (NCT04660396)
- Testing
- BVA-100
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Daxor Corporation
Blood Pressure Determination, Hemodynamic Monitoring
Continuous Vs Intermittent Non Invasive Blood Pressure Monitoring in Preventing Post Operative Organ Failure
Continuous non-invasive arterial pressure monitoring has the potential to decrease the duration of intraoperative hypotension and hypertension compared to conventional intermittent blood pressure monitoring. Chen et al.
- Conditions
- Blood Pressure Determination, Hemodynamic Monitoring, Postoperative Complications
- Trial name
- NiMon (NCT05496322)
- Testing
- Continuous Non Invasive Blood Pressure Monitoring, Intermittent Non Invasive Blood Pressure Monitoring
- Where
- Italy
- Volunteers
- 1,267 people
- Sponsor
- University of Messina
Blood Volume, Extravasation
Blood Volume and Fluid Kinetics in Patients Undergoing Extracorporal Circulation
In patients undergoing extracorporal circulation during cardiac operation, the hemoglobin is subjected to large changes. The purpose of this study is to see if it is possible with the help of volume kinetic techniques to use…
- Trial name
- NCT01115166
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- University Hospital, Linkoeping
Critical Illness, Sepsis
Enteral Glutamine in Critical Illness
Glutamine is an amino acid which is rapidly depleted in critical illness. It is used as energy by cells that line the gut, vital for immune system function, and works as an anti-oxidant.
- Conditions
- Critical Illness, Sepsis, Respiratory Insufficiency
- Trial name
- NCT00318331
- Testing
- Glutamine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Christiana Care Health Services
Fracture of Hip
Hemodynamic Monitoring and Resuscitation in Hip Fractures
Background: Fracture of the hip is a potentially fatal event in an elderly, frail, highly comorbid patient group suffering from dehydration and hypovolemia, and it carries a risk that equals major trauma in young patients in…
- Trial name
- NCT03401138
- Testing
- Preoperative Stroke Volume(SV)-guided fluid optimization
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Hvidovre University Hospital
Blood Loss
Noninvasive Monitor of Vascular Volume Fluid Shifts
Blood volume measurements are a critical step in the emergency care of trauma patients. The typical approach to this is to rely on historical information, physical examination and metrics such as heart rate.
- Trial name
- NCT05080881
- Testing
- phonocardiographic measurement: InnoVital Systems, phonocardiographic measurement: ThinkLabs StethOne, physiological measurements: BIOPAC
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center