Clinical trials: Blunt Injuries
Lung Contusion
Respiratory Function Monitoring of Mechanical Ventilation in Patients With Chest Blunt Injury
The goal of this observational study is to learn about EIT in observing the application of lung protective ventilation strategies in patients with pulmonary contusion, particularly the impact on pulmonary ventilation blood flow…
- Trial name
- NCT06386120
- Testing
- PEEP setting strategy
- Volunteers
- 80 people
- Sponsor
- Peking University People's Hospital
Blunt Chest Wall Trauma, Rib Fracture
Intercostal Liposomal Bupivacaine for the Management of Blunt Chest Wall Trauma
This is a study of liposomal bupivacaine for pain control in patients with blunt chest wall trauma.
- Conditions
- Blunt Chest Wall Trauma, Rib Fracture, Sternal Fracture
- Trial name
- NCT02749968
- Testing
- Liposomal bupivacaine, 0.9% sodium chloride
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Cincinnati
Blunt Chest Trauma
The Effect of Virtual Reality on Pulmonary Recovery and Mobility in Patients With Blunt Chest Trauma
Blunt chest trauma comprises over 10% of all trauma patients presenting to emergency departments worldwide and is the most frequent injury in polytrauma patients.
- Trial name
- VIREX PURE (NCT05194176)
- Testing
- Virtual Reality
- Where
- Netherlands
- Volunteers
- 27 people
- Sponsor
- Radboud University Medical Center
Blunt Chest Trauma
Non-Invasive Dynamic Monitoring-Guided Oscillation and Lung Expansion for Airway Clearance in Severe Blunt Chest Trauma: A Clinical Study
In our previous study, the investigators analyzed more than 30,000 cases from the National Trauma Center Database and found that 66.4% of patients with severe blunt chest trauma had concurrent rib fractures, 55.87% had multiple…
- Trial name
- NCT07432048
- Testing
- Different therapeutic interventions
- Volunteers
- 80 people
- Sponsor
- Peking University People's Hospital
Laparoscopic Surgery
Laparoscopic Splenectomy in Isolated High Grades Splenic Injuries
Background: Trauma laparoscopic splenectomy has no defined reasons. Compared trauma patient characteristics and results with laparoscopic and open splenectomies.
- Trial name
- NCT04329845
- Testing
- open splenectomy, laparoscopic splenectomy for splenic injury in trauma
- Volunteers
- 2 people
- Sponsor
- Zagazig University
Cesarean Section
Sharp Versus Blunt Fascial Incision at Caesarean Section
The purpose of this study is to compare sharp and blunt fascial entry during caesarean section on the same patient. The study is performed on woman having cesarean section for the first time and who have not previously had lower…
- Trial name
- NCT01297725
- Testing
- Blunt right, sharp left, Blunt left, sharp right
- Where
- 2 sites in Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Holbaek Sygehus
Minor Head Injury
Outcome of Patients With Mild Head Injury and Presence of an Acute Traumatic Abnormality on CT Scan of Head
Background: Patients with mild blunt traumatic brain injury (TBI) are frequently transferred to Level 1 trauma centers (L1TC) if they have any positive finding of any acute intracranial injury identified on a CT scan of the head.
- Trial name
- NCT04143347
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Massachusetts General Hospital
Chest Trauma
Validation of the STUMBL Score for Blunt Thoracic Trauma
This prospective observational study aims to validate the STUMBL score for risk stratification in emergency department patients with blunt thoracic trauma in Iraq.
- Trial name
- STUMBL (NCT06734338)
- Where
- Iraq
- Volunteers
- 188 people
- Sponsor
- Al-Nahrain University
Trauma, Trauma Injury
An Observational Study to Evaluate the Safety and Efficacy of Humacyte's HAV for Arterial Replacement or Reconstruction in Ukrainian Patients With Life or Limb-threatening Vascular Trauma
Humacyte provided HAVs as humanitarian aid to Ukraine. This retrospective observational study is designed to collect data from patients in whom the HAVs have already been implanted on a humanitarian basis between June 2022 and…
- Conditions
- Trauma, Trauma Injury, Trauma, Multiple, Trauma Blunt
- Trial name
- NCT05873959
- Testing
- HAV implantation
- Where
- 3 sites in Ukraine
- Volunteers
- 17 people
- Sponsor
- Humacyte, Inc.
Blunt Trauma to Abdomen, Wounds and Injuries
A Research Study of Abdominal Ultrasound (FAST) in Children With Blunt Torso Trauma
Bleeding from intra-abdominal injuries is a leading cause of traumatic deaths in children. Abdominal CT is the reference standard test for diagnosing intra-abdominal injuries.
- Conditions
- Blunt Trauma to Abdomen, Wounds and Injuries, Abdomen Injury, Abdominal Injury
- Trial name
- FAST (NCT05910567)
- Testing
- Focused Assessment with Sonography for Trauma (FAST) Examination, No Intervention: Standard of Care - Without the FAST Examination
- Where
- 6 sites in United States
- Volunteers
- 4,650 people
- Sponsor
- University of California, Davis
Ascites, Blunt Abdominal Trauma
Telesonography Adaptation and Use to Improve the Standard of Patient Care Within a Dominican Community
The role of teleradiology has far reaching implications for the health of remote and underserved populations. The ability to coordinate radiographic evaluation and diagnosis from a distance has the potential to raise the standard…
- Conditions
- Ascites, Blunt Abdominal Trauma, Cholelithiasis, Cholecystitis
- Trial name
- NCT00591968
- Testing
- SonoSite Titan portable ultrasound coupled with email telediagnosis
- Where
- Dominican Republic
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Post-traumatic Facial Edema
Lymphedema Treatment for Blunt Facial Trauma
Injuries to the face caused by traumatic events such as motor vehicle collisions, assault, and falls can result in facial trauma, which can result in swelling and disfiguration that impairs the important functions of the face…
- Trial name
- NCT02977182
- Testing
- Complete Decongestive Therapy (CDT)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Our Lady of the Lake Hospital
Blunt Injury of Thorax, Multiple Rib Fractures, Involving Three Ribs
Low Dose Ketamine for Blunt Thoracic Trauma
The goal of this Randomized controlled double-blinded trial is to compare the addition of a ketamine infusion to placebo, when added to standard care in adult blunt trauma patients with multiple rib fractures.
- Trial name
- NCT06236113
- Testing
- Ketamine 1 Mg/mL-NaCl 0.9% Intravenous Solution
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- North Memorial Health Care
Ankle Sprains
Phase III Trial to Evaluate the Efficacy and Safety in Patients With Ankle Sprains.
This study is a multi-center, double-blind, randomized controlled trial to evaluate the efficacy and safety of EFTS vs. placebo in patients with ankle sprains.
- Trial name
- NCT06866613
- Testing
- Esflurbiprofen Topical System (EFTS)
- Where
- 5 sites in Germany
- Volunteers
- 69 people
- Sponsor
- Teikoku Seiyaku Co., Ltd.
Wounds and Injuries
Splenic Injury Embolization - the Question About NOM (SInE Qua NOM)
The primary objective is to compare the failure rate due to splenic bleeding between the patients undergoing pre-emptive splenic arterial embolization (SAE) as part of non-operative management (NOM) and the patients not…
- Trial name
- NCT03231202
- Testing
- Embolization
- Where
- 12 sites in United States, Australia and 7 more
- Volunteers
- 224 people
- Sponsor
- Oslo University Hospital
Blunt Chest Trauma, Acute Respiratory Distress Syndrome
Statins and Selective Cyclooxygenase-2 Receptor Inhibitors in Blunt Chest Trauma
Background: Lung contusion affects 17%-25% of adult blunt trauma patients, and is the leading cause of death from blunt thoracic injury.
- Trial name
- NCT01623921
- Testing
- standard care treatment, Celecoxib, Rosuvastatin
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Blunt Abdominal Trauma, Abdominal Injuries
Evaluation of the Blunt Abdominal Trauma Severity Score (BATSS) in Blunt Abdominal Trauma
Blunt abdominal trauma (BAT) is a leading cause of trauma-related morbidity and mortality, commonly caused by motor vehicle collisions, falls, and assaults.
- Conditions
- Blunt Abdominal Trauma, Abdominal Injuries, Intra-Abdominal Injury
- Trial name
- NCT07803211
- Volunteers
- 120 people
- Sponsor
- Assiut University
Blunt Abdominal Trauma
Pelvic CT Imaging in Blunt Abdominal Trauma
Abdominopelvic CT (CTap) utilization rose significantly in blunt trauma patients over the last decade. However, the observed increases failed to reduce mortality or missed injury rates.
- Trial name
- NCT01828749
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- Wake Forest University Health Sciences
Chest Injuries, Respiratory Failure
Early Non-invasive Ventilation and High-flow Nasal Oxygen Therapy for Preventing Delayed Respiratory Failure in Hypoxemic Blunt Chest Trauma Patients.
In blunt chest trauma patients without immediate life-threatening conditions, delayed respiratory failure and need for mechanical ventilation may still occur in 12 to 40% of patients, depending on the severity of the trauma, the…
- Trial name
- OptiTHO (NCT03943914)
- Testing
- Preventive strategy, Standard of care
- Where
- 14 sites in France
- Volunteers
- 144 people
- Sponsor
- University Hospital, Bordeaux
Liver Injury
Non-Operative Management of High Grade Blunt Hepatic Injury: Clinical Complications and the Role of Collateral Damage
Little is known about the role of collateral damage in patients with high grade liver injuries (LI). This retrospective single centre study investigates the safety of the non-operative management of patients with high grade blunt…
- Trial name
- NOMLI (NCT00694499)
- Where
- Switzerland
- Volunteers
- 183 people
- Sponsor
- University of Bern