Clinical trials: Blunt Trauma
Rib Fractures
Suzetrigine for Acute Pain Control in Patients With Multiple Rib Fractures
Rib fractures cause a significant amount of pain and are associated with an increased risk of lung infections, long hospitalization, and increased cost.
- Trial name
- NCT07145346
- Testing
- Suzetrigine (SUZ)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of California, Irvine
Thrombosis of Portal Venous System.
Evaluation of Portal Venous System Thrombosis After Blunt Splenic Trauma Utilizing Doppler Ultrasound
The true incidence of thrombosis in the portal venous system after blunt splenic trauma is unknown and has not been elucidated in the medical literature.
- Trial name
- NCT01906983
- Testing
- Doppler Ultrasound
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Rambam Health Care Campus
Ankle Sprains
Phase III Trial to Evaluate the Efficacy and Safety in Patients With Ankle Sprains.
This study is a multi-center, double-blind, randomized controlled trial to evaluate the efficacy and safety of EFTS vs. placebo in patients with ankle sprains.
- Trial name
- NCT06866613
- Testing
- Esflurbiprofen Topical System (EFTS)
- Where
- 5 sites in Germany
- Volunteers
- 69 people
- Sponsor
- Teikoku Seiyaku Co., Ltd.
Carotid Artery Injury, Vertebral Artery Injury
Anticoagulation in Blunt Cerebrovascular Injuries
Originally thought to be a rare occurrence, BCVI are now diagnosed in approximately 1% of blunt trauma patients. Initially BCVI were thought to have unavoidable devastating neurologic outcomes.
- Trial name
- NCT00494156
- Testing
- heparin, aspirin and clopidogrel
- Where
- United States
- Sponsor
- C. Clay Cothren, MD
Patient/Ventilator Asynchrony
Study to Measure the Prevalence of Asynchrony In Mechanically Ventilated Patients
This study will examine the prevalence of patient-ventilator asynchrony and its determinants. Mechanically ventilated trauma patients often experience asynchrony when their pattern of breathing does not match the triggering of a…
- Trial name
- Asynchrony (NCT01049958)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Cincinnati
Abdominal Injuries, Wounds and Injuries
Predictors of In-Hospital Mortality in Severe Abdominal Trauma
Severe abdominal trauma is a leading cause of early death from bleeding and of later death from sepsis and organ failure. Clinicians use scoring systems to estimate the risk of dying, but most of these scores were developed and…
- Conditions
- Abdominal Injuries, Wounds and Injuries, Wounds, Nonpenetrating, Wounds, Penetrating
- Trial name
- NCT07843628
- Where
- Egypt
- Volunteers
- 430 people
- Sponsor
- Minia University
Renal Injury
Prospective Evaluation of Blunt Renal Injury in Children
The objective of this study is to evaluate the outcomes of children who have sustained blunt renal injury and to evaluate our current bed rest protocol.
- Trial name
- NCT00855036
- Testing
- Attenuated bedrest
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Children's Mercy Hospital Kansas City
Rib Fractures
Long-term Outcome After Removal of Rib Stabilization Hardware in Patients With Blunt Chest Trauma
The main study objective is to evaluate the long-term outcome in a prospective follow-up visit of patients who underwent hardware removal after surgical stabilization of rib fractures (SSRF) after a blunt chest trauma .
- Trial name
- REMOVE (NCT06003595)
- Testing
- Data collection on patient reported long-term outcome of SSRF hardware removal
- Where
- Switzerland
- Volunteers
- 28 people
- Sponsor
- University Hospital, Basel, Switzerland
Abdominal Injuries, Thoracic Injuries
TRACT Study: Evaluation of the Value of Routine Thoraco-abdominal CT in Blunt Trauma Patients
The aim of this study is to establish the additional effectiveness and costs of routine thoraco-abdominal computed tomography (CT) in blunt trauma patients versus conventional radiological imaging and to determine which clinical…
- Trial name
- NCT00228111
- Where
- Netherlands
- Volunteers
- 1,000 people
- Sponsor
- Radboud University Medical Center
Blunt Injury of Thorax
High Flow Nasal Cannula vs Noninvasive Ventilation in Patients With Hypoxic Respiratory Failure Following Blunt Chest Trauma
to compare high flow nasal cannula against noninvasive ventilation in patients with non-sever blunt chest trauma in improvement of oxygenation, need for intubation and mechanical ventilation within 28 days
- Trial name
- NCT05527431
- Testing
- high flow nasal cannula, noninvasive ventilation
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Wounds and Injuries
Splenic Injury Embolization - the Question About NOM (SInE Qua NOM)
The primary objective is to compare the failure rate due to splenic bleeding between the patients undergoing pre-emptive splenic arterial embolization (SAE) as part of non-operative management (NOM) and the patients not…
- Trial name
- NCT03231202
- Testing
- Embolization
- Where
- 12 sites in United States, Australia and 7 more
- Volunteers
- 224 people
- Sponsor
- Oslo University Hospital
Ocular Injury
Study of Retinal Vascular Changes After Ocular Blunt Trauma
This study evaluates the retinal vascular features using optical coherence tomography angiography in patients that received ocular blunt trauma.
- Trial name
- NCT04546997
- Testing
- Optical Coherence Tomography Angiography
- Where
- Italy
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Federico II University
Orthopaedic Injury
Socio-Economic Survey in Uganda
This study will be conducted at Mulago Teaching Hospital. Patients coming to the ER with an orthopaedic injury will be approached. If a patient consents to be part of the study, they will complete a questionnaire.
- Trial name
- NCT01971697
- Where
- 2 sites in United States, Uganda
- Volunteers
- 30 people
- Sponsor
- Duke University
Thoracic Injuries, Non-invasive Ventilation
Optimization of Positive End Expiratory Pressure by Use of Pulmonary Ultrasound for Patients With Blunt Chest Trauma Treated by Non-Invasive Ventilation (Opti-PEP).
This is an open-label, randomized controlled study comparing two non-invasive ventilation initiation strategies.Patients may be included if they present with acute respiratory failure related to blunt chest trauma.The…
- Trial name
- Opti-PEP (NCT06072339)
- Testing
- Lung Ultrasound for PEEP setting, Non invasive ventilation session, Arterial blood gas
- Where
- France
- Volunteers
- 19 people
- Sponsor
- University Hospital, Montpellier
Lung Contusion
Respiratory Function Monitoring of Mechanical Ventilation in Patients With Chest Blunt Injury
The goal of this observational study is to learn about EIT in observing the application of lung protective ventilation strategies in patients with pulmonary contusion, particularly the impact on pulmonary ventilation blood flow…
- Trial name
- NCT06386120
- Testing
- PEEP setting strategy
- Volunteers
- 80 people
- Sponsor
- Peking University People's Hospital