Clinical trials: Body Composition Change
Obesity & Overweight, Weight Loss
GLP-1 Medication & Behavioral Health Programs on Weight & Metabolic Outcomes: FLOURISH and THRIVE Prospective Cohort Study
This research program includes two coordinated prospective studies (FLOURISH and THRIVE) evaluating the real-world effectiveness of Noom's digital health programs on weight, cardiometabolic biomarkers, physiological health…
- Conditions
- Obesity & Overweight, Weight Loss, Preventative Health, Body Weight
- Trial name
- FLOURISH (NCT07588984)
- Testing
- Noom Weight, Free Tier, Education-only control
- Where
- United States
- Volunteers
- 2,310 people
- Sponsor
- Noom Inc.
Weight Loss
Effectiveness of ResArgin on Adult's Body Composition and Health
The goal of this clinical trial is to learn if the supplement ResArgin (a reservatrol-based supplement) works to slow down muscle loss during a period of fat loss.
- Trial name
- NCT06601049
- Testing
- ResArgin
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr. Heather Hausenblaus
Severe Acute Malnutrition
Ready to Use Therapeutic Food (RUTF) in Severe Malnourished Children
1. RUTF would be more effective (quicker catch-up growth by promoting more tissue accrue resulting decrease stay in rehabilitation ward) in treating children with SAM during the rehabilitation phase than khichuri /halwa; 2.
- Trial name
- RUTF (NCT01331044)
- Testing
- Plumpy Nut, Khichuri and Halwa
- Where
- Bangladesh
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Obesity
Evaluation of a Lifestyle Intervention After Bariatric Surgery
The aim of this trial is to evaluate the effect of a post-surgery 12-month lifestyle intervention compared to usual care upon post-surgery weight loss and changes that occur in body composition (relative amounts of body fat…
- Trial name
- NCT03214471
- Testing
- Lifestyle intervention
- Where
- United Kingdom
- Volunteers
- 153 people
- Sponsor
- University College, London
Obesity
Anti-psychotic Medication (Stable Dose) Weight Loss Study
This is a pilot study to determine the safety and efficacy of an investigational product (IHBG-10) on weight change and changes in body composition in subjects who have been taking a stable dose of certain anti-psychotic…
- Trial name
- NCT01272765
- Testing
- IHBG-10
- Where
- United States
- Sponsor
- Avera McKennan Hospital & University Health Center
Hematopoietic Stem Cell Transplantation, Malnutrition
Body Composition Changes During Stem Cell Transplantation: The Case Of Lymphoma Patients
Skeletal Muscle Index (SMI) and Visceral Adipose Ratio (VAR) assess body composition changes and disclose malnutrition risk effectively.
- Conditions
- Hematopoietic Stem Cell Transplantation, Malnutrition, Metabolic Syndrome
- Trial name
- NCT02983643
- Where
- Lebanon
- Volunteers
- 105 people
- Sponsor
- American University of Beirut Medical Center
Focus of Study: 1- Effect of Tea Consumption on Gut Microbiota, Focus of Study: 2- Effect of Tea Consumption on Body-iron Status
Can the Reduction of Iron Availability Caused by Tea Consumption Change the Gut Microbiota Composition and Disrupt Host Body-iron Status
Iron is an essential micronutrient for nearly all living organisms, including microbes. The adult human body contains approximately 3-5 g of iron (45-55 mg/kg of body weight in adult women and men, respectively).
- Trial name
- NCT05019573
- Testing
- Black tea
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Reading
Cancer, Cancer Cachexia
Protein-rich Nutritional Therapy Combined With Time-efficient Exercise in Cancer Therapy
This study aims to evaluate the effects of a 12-week protein-rich individualized nutritional therapy combined with different time-efficient exercise programs on overall physical fitness (cardiorespiratory fitness and muscular…
- Conditions
- Cancer, Cancer Cachexia, Inflammation
- Trial name
- PROTECT (NCT04065815)
- Testing
- Resistance Training, WB-EMS, High-intensity interval training (HIIT)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Septic Shock
Expression of Protein Tyrosine Phosphatase 1B (PTP1B) and Body Composition Modification in Patients With Septic Shock
With a prevalence of more than 15% in ICU, septic shock today represents a real public health problem and remains the leading cause of mortality in ICU.
- Trial name
- Coc-SEPP1B (NCT03189355)
- Testing
- Blood sampling, Bioelectrical impedance vector analysis, Muscular echography
- Where
- France
- Volunteers
- 52 people
- Sponsor
- University Hospital, Rouen
Obesity, Sedentary Lifestyle
Exercise After Clinically Significant Weight Loss
The Prescribed Exercise to Reduce Recidivism After Weight Loss Pilot (PREVAIL-P) study will evaluate the effect of aerobic exercise training amount on weight maintenance following clinically significant weight loss.
- Conditions
- Obesity, Sedentary Lifestyle, Insulin Resistance
- Trial name
- PREVAIL-P (NCT03685123)
- Testing
- Physical activity recommendations, Weight maintenance recommendations, OPTIFAST weight loss
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Obesity
Changes in Body- and Liver-composition During Low Calorie Diet in Morbidly Obese
The purpose of this study is to determine what changes occur in body- and liver-composition during four weeks of low calorie diet in morbidly obese females
- Trial name
- NCT01842425
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Uppsala University
Undernutrition
Microbiota and Protein-energy Wasting (MIDIWA)
Oral supplementation with branched chain amino acids (BCAA) increases the levels of circulating BCAA, stimulates BCAA uptake in muscles, and decreases amino acid release from muscle, eventually promoting muscle anabolism.
- Trial name
- MIDIWA (NCT02962089)
- Testing
- Branched chain amino acids (BCAA)
- Where
- 5 sites in Switzerland
- Volunteers
- 37 people
- Sponsor
- University Hospital, Geneva
Obesity & Overweight
Changes in Body Composition Including Muscle With Anti-Obesity Medications, Both With and Without Exercise
The goal of this clinical trial is to learn whether adding either cardiovascular exercise or resistance exercise to pharmacotherapy treatment for obesity improves the retention of lean mass compared to pharmacotherapy alone in…
- Trial name
- M3-E (NCT07698145)
- Testing
- Standard Medical Care with an Obesity Management Medication, Cardiovascular Exercise Training, Resistance Exercise Training
- Where
- United States
- Volunteers
- 198 people
- Sponsor
- University of Kansas Medical Center
Body Composition, Beneficial, Oxidative Stress
Phase Angle and Body Composition, Inflammatory and Oxidative Stress Biomarkers.
The main purpose of the present study was to investigate the effects of 12 weeks of resistance training (RT) on phase angle (PhA), body composition, inflammatory and oxidative stress biomarkers, in older women and to evaluate…
- Conditions
- Body Composition, Beneficial, Oxidative Stress, Acute and Chronic Inflammation
- Trial name
- NCT02940145
- Testing
- Resistance Training
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Londrina
Rectal Cancer, Colorectal Cancer
Body Composition Manipulation in CoLorectal cancEr (BiCyCLE): Neuromuscular Electrical Stimulation (NMES)
Muscle is lost as part of the rectal cancer disease process. Surgery to treat rectal cancer and its subsequent immobility leads to increased muscle loss.
- Conditions
- Rectal Cancer, Colorectal Cancer, Colon Cancer, Colo-rectal Cancer
- Trial name
- BiCyCLE-NMES (NCT04065984)
- Testing
- Microstim 2v2 Stimulator
- Where
- United Kingdom
- Volunteers
- 46 people
- Sponsor
- London North West Healthcare NHS Trust
Head and Neck Cancer
Progressive Resistance Training Program in Head and Neck Cancer Patients
The purpose of this study is to evaluate the feasibility of a 12-week progressive resistance training (PRT) during concurrent chemoradiotherapy in head and neck cancer patients compared to usual care.
- Trial name
- NCT02068950
- Testing
- Progressive resistance training
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Herlev Hospital
Overweight and Obesity, Vitamin A Deficiency
Individualized Dietary Intervention in Breastfeeding Women: Body Weight and Vitamin A Stores
Breast milk is the best food during the first 6mo of life because it offers multiple benefits for the mother-infant pair. An inadequate maternal diet during pregnancy can lead to excess weight gain, leading to negative health…
- Conditions
- Overweight and Obesity, Vitamin A Deficiency, Dietary Modification, Breastfeeding
- Trial name
- NCT03640104
- Testing
- Intervention-Nutrition guidelines, Nutrition guidelines
- Where
- Mexico
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad de Sonora
Cachexia-Anorexia Syndrome
Exercise Intervention for Patients With Cancer Cachexia: Effects of a 12-week Program and One-year Follow-up.
The prevalence of cancer with cachexia is rising sharply. More than 80% of digestive cancer patients are affected by cancer cachexia.
- Trial name
- 2CAPA (NCT06323733)
- Testing
- Exercise Intervention
- Where
- France
- Volunteers
- 31 people
- Sponsor
- Peyrachon Romane
Pediatric Obesity
Body Composition Changes With Albuterol and Caffeine Versus Placebo in Adolescents
The purpose of this study is to determine whether taking a combination of caffeine and albuterol three times per day will increase muscle and decrease fat in your child's body and to determine how these medications make your…
- Trial name
- CAMP (NCT02740660)
- Testing
- Caffeine 100mg / Albuterol 4mg, Family weight management counseling
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Obesity (BMI Equal to or >30), Weight Regain After Bariatric Surgery
Changes in Body Composition Following Pharmacological Treatment for Obesity.
Background: Intentional weight loss via various treatments results in a loss of lean mass of approximately 10% for every 10 kg of total weight lost.
- Trial name
- NCT07908940
- Where
- Spain
- Volunteers
- 116 people
- Sponsor
- Hospital San Carlos, Madrid