Clinical trials: Body Composition Change
Weight Loss, Cachexia
Nutritional Problems and Changes in Body Composition in Patients With Non-small Cell Lung Cancer (LEKS)
Weight loss and loss of lean body mass are common and associated with adverse outcomes such as loss of strength, reduced immune- and pulmonary function and increased disability in advanced cancer.
- Trial name
- LEKS (NCT01865903)
- Where
- Norway
- Volunteers
- 17 people
- Sponsor
- Oslo University Hospital
Obesity Rekated Cancer, Body Composition Changes
Changes in Body Composition of Patients With Obesity Related Tumors and Their Impact on Clinical Outcomes: a Multicenter Prospective Cohort Study
Over the past 20 years, China's obesity rates have surged, increasing cancer burden. Obesity links to 13 cancers via metabolic effects of visceral fat and insulin resistance, while sarcopenic obesity (BMI-independent) may worsen…
- Conditions
- Obesity Rekated Cancer, Body Composition Changes, Survival, Mechanism
- Trial name
- NCT07161167
- Where
- China
- Volunteers
- 6,743 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Lung Cancer
Effect on the Nutritional and Inflammatory Status of Docosahexaenoic Acid (DHA) and Eicosapentaenoic Acid (EPA)- Containing Supplement in Patients With Advanced Lung Cancer
Background: A frequent manifestation of advanced lung cancer is malnutrition, timely identification and treatment of which can lead to improved patient quality of life, response rate to chemotherapy and survival.
- Trial name
- NCT01048970
- Testing
- Nutritional Assessment, EPA-DHA arm
- Where
- 2 sites in Mexico
- Volunteers
- 120 people
- Sponsor
- National Institute of Cancerología
Type 1 Diabetes, Overweight , Obesity
Lean Mass Changes With Semaglutide in Adults With Type 1 Diabetes and Overweight/Obesity.
The goal of this 24 week double-blinded, randomized, parallel controlled clinical trial is to learn how semaglutide affects body composition in adults with type 1 diabetes and overweight/obesity.
- Trial name
- SEMA-T1D-BODY (NCT07891156)
- Testing
- Semaglutide
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Weight Loss, Metabolism and Nutrition Disorder
The Effect of High vs. Moderate Protein Consumption on Human Health
The study will be conducted as a parallel randomized controlled intervention trial, initiated by eight weeks rapid weight loss with one of two VLCDs, one week of reintroducing regular foods, and 12 weeks with one of two different…
- Conditions
- Weight Loss, Metabolism and Nutrition Disorder, Obesity
- Trial name
- BEEF (NCT04156165)
- Testing
- VLCD-Active, Maintenance-Active, VLCD-Control
- Where
- Denmark
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Perimenopausal Women, Body Composition Changes
Nutritional Supplementation on Physiological and Metabolic Markers in Females
The goal of this clinical trial is to learn if a 12-week nutritional supplement can result in significant changes in the body composition of 38-55-year-old females.
- Trial name
- NCT07615777
- Testing
- Nutritional Supplement
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Obesity
Effect of Low-calorie Diet and Orange Juice on Body Weight and Metabolic Parameters of Obese Subjects
This study aimed to verify if combination of a low calorie diet and orange juice consumption results in weight loss and ameliorates metabolic obesity-related biomarkers.
- Trial name
- LCD-OJ-OBESE (NCT02914249)
- Testing
- Orange juice (500 mL/d)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- São Paulo State University
Cachexia; Cancer
The Effect of Colon Cancer on Muscle Gene Expression, Body Composition, Muscle Function, and Muscle Metabolism
Rationale: Cancer cachexia is a complex metabolic syndrome characterized by clinically relevant loss of muscle mass with or without loss of fat mass.
- Trial name
- COMUNEX (NCT03789136)
- Testing
- Not applicable, observational study
- Where
- Netherlands
- Volunteers
- 55 people
- Sponsor
- Wageningen University
Spinal Cord Injury, Spinal Cord Injuries
Testosterone Therapy With or Without Finasteride After Spinal Cord Injury: TRT-SCI Trial
Spinal cord injury (SCI) results in lower limb muscle loss, bone loss, and high fat mass that impede the recovery of physical function, increase bone fracture risk, and worsen health and quality of life.
- Conditions
- Spinal Cord Injury, Spinal Cord Injuries, Injuries, Spinal Cord, Spinal Cord Contusion
- Trial name
- TRT-SCI (NCT07742553)
- Testing
- testosterone cypionate, finasteride
- Where
- 4 sites in United States
- Volunteers
- 300 people
- Sponsor
- VA Office of Research and Development
Obesity, Weight Loss
The Big Breakfast Study
This weight loss study will investigate the impact of diet composition and meal size (large breakfast meals and smaller evening meals) on body weight, energy balance and eating behaviour, by altering calorie (meal) distribution.
- Trial name
- NCT03077295
- Testing
- High Fibre, High Protein
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Type 2 Diabetes, Obesity and Overweight
Meal Frequency and Timing on Metabolic Health in Patients With Type 2 Diabetes
The goal of this clinical trial is to learn if changing when and how often people eat works to improve health in adults with Type 2 diabetes.
- Trial name
- NCT07674875
- Testing
- Control Arm - standard of care, Three Meal Group, Time-restricted eating
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people
- Sponsor
- Akdeniz University
Obesity
Randomized Study to Evaluate the Effect of an Investigational Product on Weight Loss and Body Composition
This is a pilot study to determine the safety and efficacy of an investigational product (IHBG-10) on weight loss, and changes in body composition.
- Trial name
- NCT01272739
- Testing
- IHBG-10
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Avera McKennan Hospital & University Health Center
Pre Diabetes, Polycystic Ovary Syndrome
Liraglutide 3mg (Saxenda) on Weight, Body Composition, Hormonal and Metabolic Parameters in Obese Women With PCOS
There is a growing need to develop pharmacologic interventions to improve metabolic function in women with polycystic ovary syndrome (PCOS).
- Conditions
- Pre Diabetes, Polycystic Ovary Syndrome, Obesity Android
- Trial name
- SAXAPCOS (NCT03480022)
- Testing
- Liraglutide Pen Injector [Saxenda]
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Woman's
Chronic Disease
Contribution of the Evaluation of Body Composition by Connected Scale in the Effectiveness of a Reconditioning Program Through Physical Activity Adapted for Patients Suffering From Chronic Diseases
The goal of this interventional study is to evaluate the impact of the use of a connected impedance scale on the physical and mental quality of life of patients suffering from chronic diseases and participating in a physical…
- Trial name
- COCORAPA (NCT06119594)
- Testing
- Body Comp Pro connected scale (Withings manufacturer)
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pneumonia
Application of Serial Body Composition Change for Risk Prediction in Treating Patients With Severe Pneumonia
We hypothesize that serial changes of body composition in patients with pneumonia can help clinician to monitor prognosis. It was associated with underlying immune response.
- Trial name
- NCT04396522
- Testing
- noninvasively Bio-electrical Impedance Analysis (BIA)
- Where
- Taiwan
- Volunteers
- 194 people
- Sponsor
- Chang Gung Memorial Hospital
Bariatric Surgery, Exercise
Effects of a 12-week Supervised Exercise Program Post Bariatric Surgery on Body Composition, Muscle Strength, and Insulin Resistance
The goal of this clinical trial is to evaluate the impact of supervised training program on body composition, muscular strenght, insulino-resistance profile, heart rate variability and on heart structure and function between 3 to…
- Conditions
- Bariatric Surgery, Exercise, Body Composition Changes
- Trial name
- ACTIVE (NCT07651254)
- Testing
- 12-week supervised exercise program
- Where
- Canada
- Volunteers
- 61 people
- Sponsor
- Laval University
Obesity, Weight Loss
Metabolic and Behavioural Effects of CONTRAVE as Potential Mechanisms of Weight Loss in Adults With Obesity
Obesity is a common chronic disease linked with increased risk for other illnesses and earlier death. Our team and others have shown that many bodily and psychological changes occur when individuals are on calorie-restricted…
- Conditions
- Obesity, Weight Loss, Weight Management, Dietary Intervention
- Trial name
- NCT06809166
- Testing
- Contrave, Diet Program
- Where
- 3 sites in Canada
- Volunteers
- 40 people
- Sponsor
- The Royal's Institute of Mental Health Research
Obesity
Lifestyle Intervention Program for Former Elite Athletes
Given the lack of support for lifestyle management in post-career and considering the high rates of physical inactivity and overweight in former elite athletes, the aim of this research project is to analyze the efficacy and…
- Trial name
- Champ4Life (NCT03031951)
- Testing
- Lifestyle Intervention Group
- Where
- Portugal
- Volunteers
- 94 people
- Sponsor
- Faculdade de Motricidade Humana
Obesity (Disorder)
Iron Metabolism in Obesity
This study consists of two phases and aims to understand how obesity and systemic iron deficiency affect iron accumulation in important organs such as the liver and heart, as well as oxidative stress in fat tissue cells.
- Trial name
- IRON-XL (NCT07157332)
- Testing
- Bariatric Sleeve Surgery
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- TecSalud Investigación Clínica
Obesity, Morbid, Gastric Bypass
Effects of Gastric Bypass Surgery and Calcium Metabolism and the Skeleton
Obesity is a chronic illness of staggering proportions. Because weight loss through diet and exercise is difficult to attain and maintain, there has been escalating interest in bariatric surgery, including Roux-en-Y gastric…
- Trial name
- NCT01330914
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- VA Office of Research and Development