Clinical trials: Body Fat Disorder, open to volunteers
Hypercholesterolemia, Obesity
The Impact of Using a Smartphone Health Application in the Improvement of Cardiovascular Disease Risk Factors
This study investigates the effectiveness of Mobile health application (mHealth apps) in the improvement of cardiovascular disease risk factors including metabolic and behavioral factors.
- Conditions
- Hypercholesterolemia, Obesity, Diabetes Mellitus, Hypertension
- Trial name
- NCT05798442
- Testing
- smartphone health application (Opulse)
- Volunteers
- 410 people
- Sponsor
- Sultan Qaboos University
Obesity, Morbid, Obesity; Endocrine
Impact of MBS on Body Composition, Basal Metabolic Rates and Muscle Functions in Morbid Obese Patients
PRIMARY OBJECTIVE To evaluate the changes in body composition in morbid obese patients following bariatric and metabolic surgery Secondary Objectives: 1. To assess changes in BMR in obese patients following bariatric surgery 2.
- Conditions
- Obesity, Morbid, Obesity; Endocrine, Fat Disorder
- Trial name
- BARCOM (NCT07737860)
- Volunteers
- 21 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Obesity (Disorder)
JOULE - Metabolic Adaptation to Weight Loss in Response to a Behavioural Lifestyle Program With or Without Semaglutide in Adolescents With Obesity
The Joule MARS study is a single center, randomized, open label clinical trial aiming to explore the metabolic adaptations that occur in response to weight management in adolescents with obesity.
- Trial name
- JOULE-MARS (NCT06852391)
- Testing
- Semaglutide Pen Injector, Behavioural Lifestyle Program (BLP)
- Where
- Canada
- Volunteers
- 74 people
- Sponsor
- McMaster University
Bariatric Surgery Candidate, Cardiovascular Diseases
Gut Microbiota in Metabolic Surgery
Metabolic surgery is an emerging option to treat obesity-related metabolic diseases (e.g., type 2 diabetes) and prevent cardiovascular disease (CVD).
- Conditions
- Bariatric Surgery Candidate, Cardiovascular Diseases, Type 2 Diabetes, Dyslipidemias
- Trial name
- NCT05000996
- Testing
- Bariatric Surgery
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Vanderbilt University Medical Center
Cardiovascular Risk Factors, Hypertension
Clinical Management of Cardiovascular Risk Factors in Adult Patients: A Before-and-After Interventional Study
This study aims to evaluate cardiovascular risk factors, clinical characteristics, and outcomes in adult patients attending an outpatient cardiology clinic.
- Conditions
- Cardiovascular Risk Factors, Hypertension, Dyslipidemia, Type 2 Diabetes Mellitus
- Trial name
- CV-RISK (NCT07447362)
- Testing
- Structured Cardiovascular Risk Management
- Where
- Chile
- Volunteers
- 220 people
- Sponsor
- Universidad Católica San Antonio de Murcia
Prostate Cancer, Metabolic Syndrome
Akkermansia Muciniphilia and Metabolic Side Effects of ADT
The overriding objectives of this study are: 1. Primary outcomes: 1. To confirm that administration of oral acetate increases the proportion of A.
- Conditions
- Prostate Cancer, Metabolic Syndrome, Obesity, Cardiovascular Morbidity
- Trial name
- NCT05802121
- Testing
- Apple Cider Vinegar
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Western University
MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease
Study on the Function of Taiwan Green Propolis in Reducing Blood Lipids and Body Fat in Sub-healthy Groups: MASLD
This study investigates the effectiveness of Taiwanese green propolis in reducing blood lipids and body fat in sub-healthy individuals.
- Trial name
- TGP (NCT07114926)
- Testing
- Taiwanese green propolis
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kuo,HSIN-YU
High Blood Glucose, High Cholesterol
FELLAShip to Better Health
The goal of this clinical trial is to evaluate the implementation and effectiveness of the FELLAship program-a church-based cardiovascular health (CVH) intervention-in Black men aged 35-70 who are at risk for heart disease…
- Conditions
- High Blood Glucose, High Cholesterol, High Cholesterol/Hyperlipidemia, Blood Sugar; High
- Trial name
- NCT07220213
- Testing
- FELLAship
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Alabama at Birmingham
Hyperlipidemia in Children
Virtual Reality Intervention in Children With Hyperlipidemia
Children with hyperlipidemia have elevated blood lipid levels, which increase the risk of developing cardiovascular diseases later in life.
- Trial name
- NCT07344389
- Testing
- Virtual Reality Training, Conventional Physiotherapy
- Volunteers
- 32 people
- Sponsor
- Hacettepe University
Foreign-Body Reaction, Granulomatous Disease
Prospective Stage-Stratified Histopathologic Study and Proposed Disease-Evolution Model of Gluteal Permanent Synthetic Filler Complications
This prospective biospecimen cohort will collect and analyze tissue from adults undergoing clinically indicated surgery for gluteal permanent synthetic filler disease.
- Conditions
- Foreign-Body Reaction, Granulomatous Disease, Soft Tissue Necrosis Lower Limb, Gluteal Permanent Synthetic Filler Disease
- Trial name
- NCT07808970
- Testing
- Standardized Tissue Sampling During Clinically Indicated Surgery, Blinded Histopathologic Scoring
- Where
- Colombia
- Volunteers
- 200 people
- Sponsor
- Research Inc
Obesity (Disorder)
Effects of Bariatric Surgery on Cardiovascular Risk Profile in Relation to Inflammatory Parameters: Endothelial Phenotyping and Analysis of the Cross-talk Between Adipose Tissue and Endothelium
This research project aims to study how obesity affects the heart and metabolism, and how these effects change after significant weight loss following bariatric surgery.
- Trial name
- BARIHEART (NCT07131605)
- Testing
- Before bariatric surgery, both blood and biological samples (stool and urine) will be collected. Patients will also undergo a cardiology examination
- Where
- Italy
- Volunteers
- 85 people
- Sponsor
- Maria Cecilia Hospital
Dyslipidemia, Insulin Resistance Syndrome
Prescription of Step Counts for Targeted Changes in Body Composition and Cardiometabolic Risk in Overweight/Obese Adults
The prevalence of overweight and obesity remains epidemic in the United States, with some of the highest rates seen in older adults.
- Conditions
- Dyslipidemia, Insulin Resistance Syndrome, Hypertension, Inflammation Chronic
- Trial name
- NCT07221279
- Testing
- Step counts for predictable changes in body weight/compositon and cardiometabolic risk
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kennesaw State University
Breast Neoplasms, Body Composition
Longitudinal Body Composition Assessment in Breast Cancer Patients
This observational cohort study aims to track longitudinal changes in body composition, including skeletal muscle mass and fat distribution, in patients diagnosed with breast cancer.
- Conditions
- Breast Neoplasms, Body Composition, Sarcopenia, Fat Redistribution
- Trial name
- NCT07472803
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Stress Mental, Dyslipidemia
Effect of macaúba Oil Combined With Green Exercises
Animal model studies involving macaúba oil demonstrate beneficial effects on fat, oxidative stress, and adipogenesis. This study aims to evaluate lipid oxidation and mental stress levels in trained individuals following macaúba…
- Conditions
- Stress Mental, Dyslipidemia, Obesity & Overweight
- Trial name
- NCT07715461
- Testing
- Macauba oil, Daytime Green Exercise, Nighttime Green Exercise
- Where
- 2 sites in Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Postmenopausal Symptoms, Obesity
Exercise Training and Fat Metabolism in Postmenopausal Women
Adipose tissue turnover plays a critical role in body weight maintenance, and obesity is underscored by the dysregulated balance between fat breakdown and synthesis.
- Conditions
- Postmenopausal Symptoms, Obesity, Prediabetic State
- Trial name
- NCT05351476
- Testing
- Resistance Exercise, Endurance Exercise
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Florida State University
Obesity, Overweight and Obesity
Tirzepatide: Reversal of Lipotoxicity and Adipose Tissue Dysfunction in Humans With Overweight/Obesity
Obesity, affecting 40% of US adults and costing 173b annually, represents a significant health care burden (1). It is associated with increased risk for multiple chronic diseases including hypertension, type 2 diabetes (T2D)…
- Conditions
- Obesity, Overweight and Obesity, Overweight
- Trial name
- NCT05912621
- Testing
- Tirzepatide
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obstructive Sleep Apnea, Fat Disorder
Metabolism and Sleep Apnea Treatment
The purpose of this research study is to see if obstructive sleep apnea (OSA) is associated with abnormalities in fat metabolism.
- Trial name
- MaST (NCT05539716)
- Testing
- PAP Therapy, Lifestyle Counseling Intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Miami
Overweight and Obesity
Effects of Watermelon or Low-fat Cookie Consumption on Wellness
The objective of the proposed research is to determine the effects of fresh watermelon consumption on physiological indicators of wellness regarding sexual, skin and gut health in adults.
- Trial name
- NCT06323070
- Testing
- Low-fat cookies, Watermelon
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Diabetes, Pre Diabetes
Jockey Club Precision Prevention Programme on Young Onset Diabetes
This is a community-based implementation program consisting of multiple components delivered by a multidisciplinary team to detect and prevent young onset diabetes with precision and value using biogenetic markers, digital tools…
- Conditions
- Diabetes, Pre Diabetes, Hypertension, Dyslipidemia
- Trial name
- NCT06693934
- Testing
- Risk assessment with biogenetic and clinical test to predict diabetes risk, Oral glucose tolerance test (OGTT) and cardiovascular-kidney-metabolic (CKM) risk factors, Medication
- Where
- Hong Kong
- Volunteers
- 9,000 people, healthy volunteers welcome
- Sponsor
- Juliana CN Chan
Obesity, Metabolic Syndrome
Integrated Traditional Chinese Medicine Day Care Program for Metabolic Syndrome
The goal of this study is to evaluate if a integrated tradtional Chinese medicine (TCM) program for improving metabolic syndrome is applicable.
- Conditions
- Obesity, Metabolic Syndrome, Dyslipidemias, Diabetes Mellitus
- Trial name
- NCT06703788
- Testing
- A fiixed combination of Chinese herbal medicine, Laser acupuncture
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Chang Gung Memorial Hospital