Clinical trials: Body Fat Distribution
Changes in Bone Mineral Content, Changes in Bone Marrow Adipose Tissue
Tissue Partitioning in Early Childhood
Early childhood (~4-6 years of age) is an important window for determining body composition trajectory and may be a critical period for the development of tissue partitioning patterns that influence later disease risk, including…
- Trial name
- NCT01041794
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Healthy
The Effect of Calorie Deprivation on Adipose Tissue Distribution
In this study, we will be studying the effects of acute calorie deprivation (a 10-day fast) on bone marrow fat, other fat stores and bone parameters.
- Trial name
- NCT01658397
- Testing
- Fasting
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Absorption
Study of Tocotrienol Absorption and Distribution Under Different Fat Status
Despite the emerging interest in tocotrienols, the absorption of tocotrienols in humans remains unclear especially with different fat diets.This study aimed at evaluating the absorption and distribution of tocotrienols in plasma…
- Trial name
- NCT01185769
- Testing
- Tocotrienol
- Where
- Malaysia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Malaysia Palm Oil Board
Obesity, Bariatric Surgery
App-technology to Improve the Level of Physical Activity After Bariatric Surgery
The aim of this study is to investigate the effect of using new app-based technology to increase the level of physical activity, compared to conventional postoperative information given to patients undergoing bariatric surgery.
- Conditions
- Obesity, Bariatric Surgery, Exercise, Quality of Life
- Trial name
- NCT03480464
- Testing
- App-technology to increase physical activity
- Where
- Sweden
- Volunteers
- 158 people
- Sponsor
- Karolinska Institutet
Overfeeding
Polyphenols and Overfeeding
Obesity is a complex and multifactorial disease representing a major public health challenge. Indeed, overweight and obese people carry a major risk of developing insulin resistance and type 2 diabetes mellitus.
- Trial name
- Poly-Nut (NCT02145780)
- Testing
- 2g of grape polyphenol extract
- Where
- France
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Cardiovascular Diseases, Coronary Disease
Ischemic Heart Disease Incidence and Indices of Body-fat Distribution
To determine the association between ischemic heart disease incidence and anthropometric indices of body-fat distribution.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Ischemia
- Trial name
- NCT00005255
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
HIV-associated Hypertriglyceridemia, HIV-associated Hypercholesterolemia
Effect of DHA on Lipid and Carbohydrate Metabolism Alterations and Body Fat Distribution in HIV Patients Under HAART.
Highly active antiretroviral therapy (HAART) is able to cause lipid metabolism and glucose homeostasis alterations, which are associated to the redistribution of body fat.
- Conditions
- HIV-associated Hypertriglyceridemia, HIV-associated Hypercholesterolemia, HIV-associated Inflammatory State
- Trial name
- NCT02005900
- Testing
- Docosahexaenoic acid (DHA) administration to modulate Triglycerides in HIV patients under HAART
- Where
- Spain
- Volunteers
- 66 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Hormone Receptor-Positive Breast Cancer, HER2-Negative Breast Cancer
Tirzepatide for Weight Loss Intervention in Early-Stage Hormone Receptor Positive/HER2 Negative Breast Cancer
This clinical trial aims to evaluate the effectiveness of tirzepatide in achieving a 5% or more body weight reduction in patients undergoing adjuvant treatment for hormone receptor-positive, HER2-negative (HR+/Her2-) breast…
- Trial name
- FITWISE (NCT06518837)
- Testing
- Tirzepatide
- Where
- 7 sites in United States
- Volunteers
- 40 people
- Sponsor
- Rutgers, The State University of New Jersey
Polycystic Ovary Syndrome, Hypothalamic Amenorrhea
Body Fat as Determinant of Female Gonadal Dysfunction
Reproduction requires from women enough energy depots to warrant an adequate nutritional supply to the fetus. Hence, adipose tissue is able to communicate with female hypothalamic-pituitary-ovary axis.
- Trial name
- NCT03841981
- Testing
- Anthropometric and physical examination, Indirect calorimetry, accelerometer and seven-day dietary recall, Biochemical, hormonal and metabolic phenotyping
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Postmenopausal Disorder
Anthropometric, Metabolic, Cardiovascular and Symptomatic Profile in Postmenopausal Women
The purpose of this study is to investigate anthropometric, metabolic, cardiovascular and symptomatic profiles in postmenopausal women.
- Trial name
- NCT01745042
- Testing
- Clinical exams
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Overweight and Obesity, Weight Loss
PRE-Pregnancy Weight Loss And the Reducing Effect on CHILDhood Overweight - Aarhus
The study is a single site parallel randomized controlled study. The study will be assessing the effect of a 10% pre-conceptional weight loss intervention vs a control group among healthy couples where the prospective mother is…
- Conditions
- Overweight and Obesity, Weight Loss, Pregnancy Related, Child Nutrition Sciences
- Trial name
- PREPARE CHILD (NCT05798494)
- Testing
- Weight loss intervention
- Where
- Denmark
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ulla Kampmann Opstrup
Sedentary Behavior, Overweight
The Project ATA: Adipose Tissue & Adipokines
It is essential to delve deeper into the molecular and tissue aspects that allow us to recognize the roles of adipose tissue and its interaction with the musculoskeletal (i.e., adipomyokines) to facilitate the identification of…
- Conditions
- Sedentary Behavior, Overweight, Obesity
- Trial name
- ATA (NCT05758311)
- Where
- Colombia
- Volunteers
- 378 people, healthy volunteers welcome
- Sponsor
- Dynamical Business and Science Society - DBSS International SAS
Diabetes, Diabetes Mellitus, Type 2
Comparison of the Change in Fat Distribution in Overweight and Obese Subjects With Type 2 Diabetes After Insulin Treatment
This trial is conducted in Europe. The aim of this clinical trial is to compare the change in trunk fat mass, assessed by Double Energy X-ray Absorptiometry (DEXA) after 26 weeks of treatment with insulin detemir or insulin NPH…
- Trial name
- NCT00795600
- Testing
- insulin detemir, insulin NPH
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Novo Nordisk A/S
Bone Mineral Density, Body Fat Distribution
The Bone-Fat-Pancreas Axis in Children
The overarching hypothesis of this proposal is that obesity and positive energy balance in children promote both low bone mass accrual and risk for diabetes through events that are mechanistically associated and that involve bone…
- Conditions
- Bone Mineral Density, Body Fat Distribution, Insulin Homeostasis
- Trial name
- NCT01041898
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Lipedema, Metabolism
Effect of Weight Loss on Body Composition and Metabolic Function in Women With Lipedema
Lipedema is a disorder characterized by massive, bilateral accumulation of fat below the waist and in the legs. Enlargement of the lower extremities is often accompanied by leg pain and accumulation of fluid.
- Trial name
- Lipedema (NCT03271034)
- Testing
- Weight loss
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Overweight and Obesity, PreDiabetes
Clinical Effectiveness of Body Fat Distribution Imaging in Real-World Practice: The BODY-REAL Study
The overall goal is to determine the real-world feasibility and utility of body fat imaging using rapid MRI to enhance risk perception, induce behavioral change, and improve clinical outcomes in overweight and obese individuals.
- Conditions
- Overweight and Obesity, PreDiabetes, Type 2 Diabetes, Cardiovascular Risk Factor
- Trial name
- BODY-REAL (NCT04763772)
- Testing
- Body Fat Distribution Imaging Report, Basic Weight Information, Patient Provided
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University Hospitals Cleveland Medical Center
Obesity, Visceral, Cardiovascular Diseases
Impact of Liraglutide 3.0 on Body Fat Distribution
This study is a clinical study to investigate the efficacy of liraglutide compared to placebo in reducing visceral adiposity measured by MRI in overweight or obese subjects at high risk for cardiovascular disease after 40 weeks…
- Conditions
- Obesity, Visceral, Cardiovascular Diseases, Fat Disorder
- Trial name
- NCT03038620
- Testing
- Liraglutide
- Where
- United States
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Menopause
Eating Chocolate at the Right Time Benefits the Circadiam Sytem and Metabolic Efficiency.
The purpose of this investigation is to test the hypothesis that in humans, eating a relatively big amount of chocolate at the wrong time (bedtime) may disrupt our circadian system (change the circadian phase), while taking this…
- Trial name
- ONTIME-CHOC (NCT03949803)
- Testing
- Chocolate 100gr
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Body Composition, Beneficial
Impact of Physiological, Lifestyle and Genetic Factors on Body Composition
Research has shown that body composition is a key component of health and future disease risk. Being overweight and obese is associated with a higher body fat composition, and a greater risk of developing type II diabetes and…
- Trial name
- BODYCON (NCT02658539)
- Where
- United Kingdom
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- University of Reading
Obesity
Craving and Lifestyle Management Through Mindfulness Study
The purpose of this study is to determine whether a mindfulness-based stress reduction and mindful eating program will lead to reductions in abdominal fat and total weight and improve cell aging in overweight and obese women…
- Trial name
- CALMM (NCT01250509)
- Testing
- Craving and Lifestyle Management through Mindfulness
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco