Clinical trials: Body Fat Distribution
Steatosis, Liver, Type2 Diabetes
Effects of Combined Dapagliflozin and Exenatide Versus Dapagliflozin and Placebo on Ectopic Lipids in Patients With Uncontrolled Type 2 Diabetes Mellitus.
SGLT2 antagonists and GLP1 agonists are used since a relatively short period as second line therapy if indicated and are well tolerated by patients featuring low risk of hypoglycaemia in comparison to insulin or other oral…
- Trial name
- EXENDA (NCT03007329)
- Testing
- Exenatide, Dapagliflozin
- Where
- Austria
- Volunteers
- 34 people
- Sponsor
- Medical University of Vienna
Healthy, Postmenopause
Fat Distribution in Healthy Early Postmenopausal Women
The aim of this study is to explore the effects of hormone replacement therapy with EV/DNG on abdominal fat distribution measured by magnetic resonance imaging.
- Trial name
- NCT00335218
- Testing
- Climodien / Lafamme (BAY86-5027)
- Where
- 3 sites in Austria
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Bayer
Endometrial Cancer
CT Assessment of BMI in Endometrial Cancer Patients
This study is a retrospective study to investigate the association between body fat distribution and sarcopenia on CT-scan and oncological outcomes in endometrial cancer patients
- Trial name
- NCT03962140
- Where
- United Kingdom
- Volunteers
- 302 people
- Sponsor
- Royal Cornwall Hospitals Trust
HIV Infection
A Comparison of Body Fat Distribution in HIV-1 Infected Patients Receiving, Since the Beginning and for at Least Two Years, an Antiretroviral Therapy Based on Efavirenz or Lopinavir/Ritonavir Combined With Tenofovir + Emtricitabine or Lamivudine
The purpose of this study is to compare the body fat distribution in Human Immunodeficiency Virus-1 (HIV-1) infected patients receiving, since the beginning and for at least two years, an antiretroviral therapy based on efavirenz…
- Trial name
- LYNX (NCT01159743)
- Where
- 26 sites in Spain
- Volunteers
- 346 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Polycystic Ovary Syndrome
Resting Metabolic Rate, Fat Distribution, Endocrine and Metabolic Features in Polycystic Ovary Syndrome
In a longitudinal, prospective and observational study, patients with PCOS and controls wore the SenseWear Armband for 2 days. Resting metabolic rati (kcal/die), total energy expenditure (MET, kcal) were evaluated.
- Trial name
- NCT03132545
- Testing
- SenseWear Armband (SWA) monitoring, total body dual-energy X-ray absorptiometry
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Diabetes Mellitus Type 2
Individualized Lifestyle Intervention in Subjects With Prediabetes
The purpose of this prospective randomized multicenter intervention study is to determine whether in the prevention of Diabetes an intensified lifestyle intervention is superior to a conventional lifestyle intervention in high…
- Trial name
- PLIS (NCT01947595)
- Testing
- intensified lifestyle intervention, normal lifestyle intervention, Single lifestyle advice
- Where
- 7 sites in Germany
- Volunteers
- 1,145 people
- Sponsor
- University Hospital Tuebingen
Menopause
Healthy Transitions: Menopause Effect on Obesity, Energy Balance, and Insulin
The purpose of this study is to determine the effect of menopause on obesity, energy balance, and insulin in postmenopausal, obese women.
- Trial name
- NCT00412269
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Obesity, Abdominal
The Impact of the Distribution of Adipose Tissue on the Occurrence of Metabolic Disorders and the Level of Cardiopulmonary Fitness
The aim of the research was to assess the impact of the distribution of abdominal fat (subcutaneous SAT and visceral VAT estimated at the height of the navel) on selected metabolic parameters and on specific parameters of…
- Trial name
- NCT05612282
- Testing
- body composition analysis, anthropometric measurements, Interview questionnaire
- Volunteers
- 91 people
- Sponsor
- Medical University of Bialystok
Obesity
Obesity and Fatty Acid Flux Comparison Trials
This study will explore factors that affect obesity and obesity-related diseases in both Caucasians and African Americans. By looking at the rate at which the human body burns calories while at rest (resting energy expenditure…
- Trial name
- NCT00074945
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Atherosclerosis, HIV Infections
Rosiglitazone (Avandia®) Treatment in HIV: Its Effect on Blood Vessels
This trial will study the effect of rosiglitazone on the progression of atherosclerosis (hardening of blood vessels) through improvements of the sugar and fat metabolism (body buildup, breakdown and excretion of sugar and fat).
- Trial name
- NCT00143624
- Testing
- Rosiglitazone maleate
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of British Columbia
Obesity
Effects of GLP-1 Receptor Agonist on Fat Redistribution and Inflammatory Status
GLP-1 receptor agonists promote fat redistribution in obese women with type 2 diabetes, reduce liver fat content, improve the inflammation state
- Trial name
- NCT02118376
- Testing
- Exenatide
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shanghai 10th People's Hospital
Polycystic Ovary Syndrome
The Changes of Body Fat Distribution in Obese Patients With PCOS After LSG
Polycystic ovary syndrome (PCOS) is a common endocrine disorder, with a prevalence of 5% to 15% in premenopausal women. Patients with PCOS presents as abnormal menstruation, ovulation disorders and/or hyperandrogenemia, and often…
- Trial name
- NCT04690634
- Testing
- laparoscopic sleeve gastrectomy (LSG)
- Where
- China
- Volunteers
- 153 people
- Sponsor
- Shanghai 10th People's Hospital
Obesity, Lipid Metabolism
Metabolic Fate Modifications of Saturated Fats After an Overfeeding
The purpose of this study is to determine the partitioning of exogenous lipids in the postprandial period while a study of overfeeding.
- Conditions
- Obesity, Lipid Metabolism, Inflammation
- Trial name
- SURNUT (NCT00905892)
- Testing
- Hyperlipidic overfeeding
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Centre de Recherche en Nutrition Humaine Rhone-Alpe
HIV Infections, Lipodystrophy
A Study of Increased Lactic Acid and Abnormal Fat Distribution in HIV-Positive Patients
The purpose of this study is to see if the findings of increased lactic acid and abnormal fat distribution get better when d4T is replaced with abacavir, abacavir plus lamivudine, or Combivir (a pill containing lamivudine plus…
- Trial name
- NCT00005764
- Testing
- Lamivudine/Zidovudine, Abacavir sulfate, Lamivudine
- Where
- 31 sites in United States
- Volunteers
- 100 people
- Sponsor
- Glaxo Wellcome
Obesity & Overweight, Obesity (Disorder)
Weight Loss and Adipose Tissue Metabolism During Conservative Treatment of Obesity
This prospective observational study investigates weight loss and metabolic changes in adults with obesity undergoing standard clinical diet-induced lifestyle treatment and counseling.
- Trial name
- 4FAT (NCT07456124)
- Testing
- Diet-Induced Weight Loss Program
- Volunteers
- 22 people
- Sponsor
- University of Helsinki
Visceral Fat
The Healthy Diet and Lifestyle Study
This pilot study aims to develop a study design to test the difference between a fasting diet and a heart healthy diet, assess participants' adherence to the study design, and to test whether either diet helps to reduce fat…
- Trial name
- HDL (NCT03639350)
- Testing
- IER+MED group, DASH group
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
Obesity
Epigenetic Regulation of Human Adipose Tissue Distribution
The purpose of this study is to collect data to help researchers better understand the different ways that women or men store fat (apple shape versus pear shape).
- Trial name
- Eiffel 2 (NCT02728635)
- Testing
- Dual-energy X-ray absorptiometry (DEXA)/ Magnetic resonance imaging (MRI) and Magnetic resonance spectroscopy (MRS), Adipose tissue biopsies, FSIGTT/ RMR
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Android Obesity, Metabolic Parameters and Adipose Tissue (AT) Gene Expression
Effect of Hula Hooping as Compared to Walking on Adipose Tissue Distribution, Metabolic Parameters and Adipose Tissue Gene Expression
o determine effects of hula-hooping on android obesity, metabolic parameters and adipose tissue (AT) gene expression.
- Trial name
- NCT01913171
- Testing
- Exercise
- Where
- Finland
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Metformin, Obesity, Abdominal
Effects of GLP-1RA on Body Weight, Metabolism and Fat Distribution in Overweight/Obese Patients With Type 2 Diabetes Mellitus
The purpose of this study is to analyze the effects of GLP-1RA on blood glucose, body weight, glucose and lipid metabolism and fat distribution in overweight/obese patients with type 2 diabetes mellitus.
- Conditions
- Metformin, Obesity, Abdominal, Diabetes Mellitus, Type 2, Abdominal Fat
- Trial name
- NCT05779644
- Testing
- Liraglutide, Semaglutide, Metformin
- Where
- China
- Volunteers
- 300 people
- Sponsor
- RenJi Hospital
Polycystic Ovary Syndrome (PCOS)
Body Fat Distribution and Its Associated Factors in Chinese Women With Polycystic Ovary Syndrome
To investigate the body fat distribution in chinese women with polycystic ovary syndrome (PCOS) and the association of those distribution with metabolic parameters, microeconomics, hormone profiles and psychological state.
- Trial name
- NCT04264832
- Testing
- Clinical data collection
- Where
- China
- Volunteers
- 733 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital