Clinical trials: Body Weight, open to volunteers
Hemodialysis Patient
A Theory-based Fluid Self-management Program
This study aims to evaluate the efficacy of an intervention guided by the IFSMT, in which structured education and digitally delivered reinforcement strategies are designed to enhance self-management processes, including…
- Trial name
- NCT07677605
- Testing
- A Theory-based fluid self-management program
- Where
- Indonesia
- Volunteers
- 160 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Class I/II Obesity
Translational Health Research Into Vascular and Neurocognitive Effects of Weight Loss
The goal of this clinical trial is to learn about the nature of brain abnormalities associated with excess body fat in healthy adults aged 35-55.
- Trial name
- THRIVE (NCT07592546)
- Testing
- semaglutide
- Where
- Canada
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Alain Dagher
Bariatric Surgery Candidate, Obesity, Morbid
The Poor Responders Study
Obesity and type 2 diabetes are major causes of illness and premature death worldwide and their incidence is increasing rapidly. Bariatric surgery is considered as the "gold-standard" surgical treatment for both conditions.
- Conditions
- Bariatric Surgery Candidate, Obesity, Morbid, Diabetes Mellitus, Type 2
- Trial name
- NCT05404061
- Testing
- Gut hormones
- Where
- United Kingdom
- Volunteers
- 220 people
- Sponsor
- Imperial College London
Diabetes Mellitus, Type 2
The eHealth Diabetes Remission Trial
Overweight patients with type 2 diabetes are offered a total diet replacement with the goal of weight loss and diabetes remission.
- Trial name
- eDIT (NCT05491005)
- Testing
- Total diet replacement, eHealth, Face-to-face
- Where
- 3 sites in Sweden
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Umeå University
Cancer-associated Cachexia
Visugromab in Cachexia International Trial
A study of how well and safely a new drug called visugromab works in people with certain kinds of cancer (including lung and bowel cancer) and unintended weight loss known as cachexia.
- Trial name
- VINCIT (NCT07112196)
- Testing
- Visugromab (CTL-002)
- Where
- 74 sites in United States, Bulgaria and 10 more
- Volunteers
- 518 people
- Sponsor
- CatalYm GmbH
Adults, GLP-1
Impact of Probiotic (UltraFlora® Triplebiotic) on Weight Evolution on People After Discontinuation of GLP-1 Treatment.
This is a randomized, double-blind, double arm study involving 128 participants who will undergo a total participation period of 12 weeks.
- Trial name
- NCT07209046
- Testing
- UltraFlora® Triplebiotic
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Metagenics, Inc.
Obesity, Metabolic Syndrome
Rutazyme Lemon Fermented Product Capsules for Metabolic Function in Adults With Obesity
This study evaluates whether a fruit- and vegetable-based fermented product (Rutazyme® lemon fermented product) taken as a capsule can improve metabolic health in adults with obesity.
- Trial name
- NCT07540949
- Testing
- Rutazyme® Lemon Fermented Product Capsule
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan Sport University
Overweight or Obesity
Efficacy and Safety of SYH2069 Injection in Obese Participants Without Diabetes.
To evaluate the efficacy and safety of SYH2069 injection compared with placebo in obese Non-diabetic Participants after 28 weeks of treatment.
- Trial name
- NCT07803991
- Testing
- SYH2069 Injection
- Where
- China
- Volunteers
- 360 people
- Sponsor
- CSPC Ouyi Pharmaceutical Co., Ltd.
Aging, Obesity & Overweight
Assessing Biological Aging in a Real-World Medical Weight Loss Program Using the LinAge2 Clinical Clock
This study examines whether routine treatment with semaglutide or tirzepatide, prescribed with lifestyle coaching in a real-world weight-management program, is associated with changes in biological age measured by the LinAge2…
- Trial name
- NCT07444073
- Testing
- Not applicable. This is an observational study.
- Where
- 2 sites in Singapore
- Volunteers
- 440 people
- Sponsor
- National University of Singapore
Gait Impairment in Stroke Patients
Spatiotemporal Gait Parameters of Healthy and Stroke Patients During Overground, Treadmill, and Body Weight Supported Treadmill Walking
Gait impairments following a stroke significantly hinder mobility and quality of life, emphasizing the need for precise assessment methods to guide effective rehabilitation strategies.
- Trial name
- NCT07034105
- Testing
- Gait Analysis
- Where
- Bangladesh
- Volunteers
- 25 people
- Sponsor
- Bangladesh University of Engineering and Technology
Low Muscle Strength, Malnutrition
Efficacy of Oral Nutritional Supplement in Community-Dwelling Adults Following Acute Care
The study aims to determine the effects of Oral Nutritional Supplement (ONS) added to usual care on body weight compared with usual care alone in community-dwelling adults aged 55 years and older who are at risk of malnutrition…
- Trial name
- NCT07753239
- Testing
- ONS, Standard of Care (SOC)
- Where
- 7 sites in Thailand
- Volunteers
- 304 people
- Sponsor
- Abbott Nutrition
Obesity and Overweight
Impact of Bariatric Surgery and Liraglutide on Cognitive-Behavioral Markers of Long-Term Weight Loss in Obesity
The present research project aims to study the effects of bariatric surgery and liraglutide administration (in patients already selected for one of these procedures) on two cognitive-behavioral processes partially supported by…
- Trial name
- Balance (NCT06720246)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Obesity
Effectiveness and Safety of Tirzepatide Among Participants With Obesity With or Without Type 2 Diabetes Mellitus (T2DM)
This is a prospective, multicenter, real-world study conducted in Bangladesh to assess the effectiveness and safety of Tirzepatide compared to structured lifestyle interventions, including dietary modifications and exercise, in…
- Trial name
- NCT07099742
- Testing
- Tirzepatide, Life Style Modification
- Where
- 3 sites in Bangladesh
- Volunteers
- 364 people
- Sponsor
- Dr. Md. Alimur Reza
Childhood Obesity, Insulin Resistance
Leipzig Adipose Tissue Childhood Cohort
In this study the investigators hypothesize that pathological alterations in adipose tissue biology already occur during the development and progression of obesity in children and adolescents.
- Trial name
- NCT02208141
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Obesity, Weight Loss
Bariatric Embolization of Arteries for the Treatment of Nonalcoholic Steatohepatitis
Obesity is an epidemic in the US. With progression of obesity, Nonalcoholic steatohepatitis (NASH) has been a growing public health issue.
- Conditions
- Obesity, Weight Loss, Body Weight, Nonalcoholic Steatohepatitis
- Trial name
- NCT02933554
- Testing
- Embospheres Microspheres
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Keith Pereira, MD:
Healthy Participants, Obesity
A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD1043 in Healthy Adult Participants Living With Overweight and/or Obesity.
The purpose of the study is to assess the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of AZD1043 following single and multiple ascending doses in healthy adult participants living with overweight and/or…
- Trial name
- NCT07511205
- Testing
- AZD1043
- Where
- 3 sites in United States, United Kingdom
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Dental Caries, Obesity Risk
Mothers' Action Project for Child Health
This randomized controlled trial will recruit Bangladeshi mothers and their young children into a 12 month intervention that provides child health and oral health education and seeks to build social networks among mothers.
- Trial name
- MAP-CH (NCT06753669)
- Testing
- health education and social network building, dental referral and educational materials
- Where
- United States
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Overweight or Obese
A Study to Evaluate MWN109 Injection in Healthy Subjects
This study is a Phase1, randomized, double-blinded, and placebo-controlled study. In each cohort, enrolled participants will be randomized to receive either placebo or MWN109.
- Trial name
- NCT06859853
- Testing
- Subcutaneous single and mutiple dose
- Where
- Australia
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Shanghai Minwei Biotechnology Co., Ltd
Weight Loss
Effect of Phaseolus Vulgaris L. Dry Extract on the Modulation of Weight and Metabolic Parameters
Evaluation of the efficacy of Phaseolus vulgaris L. dry extract on weight modulation.
- Trial name
- NCT06193577
- Testing
- Phaseolus Vulgaris L. Dry Extract
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IBSA Farmaceutici Italia Srl
HIV, Obesity
A Study to Improve Skeletal Muscle in Veterans With HIV
The Department of Veterans Affairs is the largest single provider of medical care to people with HIV in the United States. The condition of excess lipid within and around muscle, termed myosteatosis, predisposes Veterans to…
- Trial name
- NCT06845046
- Testing
- w-3 fatty acid, L-carnitine, Control Diet
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- VA Office of Research and Development