Clinical trials: Body Weight Change
Obesity, Life Style
Intensive Lifestyle Interventions to Overweight and Obese Patients in Primary Care
The goal of this clinical trial is to compare in the effect of different lifestyle interventions in overweight and obese participants.
- Conditions
- Obesity, Life Style, Lifestyle, Sedentary
- Trial name
- NCT06321809
- Testing
- intensive lifestyle
- Where
- Turkey (Türkiye)
- Volunteers
- 165 people
- Sponsor
- Duygu Ayhan Baser
Bariatric Surgery Candidate, Bone Loss
Weight Loss With Risedronate for Bone Health
This is a pilot project to determine the feasibility of recruiting, enrolling, treating, and following 24 older sleeve gastrectomy patients into a randomized controlled trial (RCT) examining the efficacy of bisphosphonate use…
- Conditions
- Bariatric Surgery Candidate, Bone Loss, Weight Loss
- Trial name
- WERISE (NCT03411902)
- Testing
- Risedronate Sodium 150 MG
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Weight Loss
Opt-IN: Optimization of Remotely Delivered Intensive Lifestyle Treatment for Obesity
The overall objective of the proposed research is to use an innovative methodological framework, the Multiphase Optimization Strategy (MOST), to design, for the first time, an optimized, scalable version of a technology-supported…
- Trial name
- Opt-IN (NCT01814072)
- Testing
- 12 Telephone Coaching Sessions, 24 Telephone Coaching Sessions, Report to Primary Care Physician
- Where
- United States
- Volunteers
- 562 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Weight Loss, Anovulation
Evaluation of Ovarian Morphology and Function in Overweight Women During Weight Loss
The objective of this study is to explore the effects of weight loss on body composition, metabolic status, reproductive hormones, and ovarian follicle development in obese women with regular menstrual cycles versus obese women…
- Conditions
- Weight Loss, Anovulation, Amenorrhea, Infertility
- Trial name
- NCT01785719
- Testing
- Commercial Weight Loss Program
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Cornell University
Weight Gain, Obesity
The GEM (Goals for Eating and Moving) Study
The GEM intervention leverages the patient-centered medical home model by using the GEM tool to provide individually tailored, patient-centered care, promote standardized weight management counseling by health coaches and primary…
- Trial name
- GEM (NCT03006328)
- Testing
- GEM, Enhanced Usual Care
- Where
- United States
- Volunteers
- 489 people
- Sponsor
- NYU Langone Health
Obesity
Incisionless Treatment for Patients With Inadequate Weight Loss Following Roux-en-Y Gastric Bypass
It is estimated that up to 20% of patients who have Roux-en-Y Gastric Bypass (RYGB) surgery will not meet their weight loss goal, or may even regain some of the weight they initially lost.
- Trial name
- NCT00394212
- Testing
- Transoral Suturing
- Where
- 10 sites in United States
- Volunteers
- 77 people
- Sponsor
- C. R. Bard
Severe Obesity
Enhancing Weight Loss Maintenance With GLP-1RA (BYDUREON™) in Adolescents With Severe Obesity
Long-term weight loss maintenance is seldom achieved by individuals with obesity owing to numerous biological adaptations involving appetite, satiety, and energy expenditure in the post- weight loss setting.
- Trial name
- NCT02496611
- Testing
- Weight loss with pharmacotherapy, Weight loss without pharmacotherapy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Metabolic Syndrome
Canadian Health Advanced By Nutrition and Graded Exercise
The overall objective of the CHANGE initiative is to change the delivery of care in primary care clinics to treat disease by reducing reliance on drugs and hospitals through the promotion of scientifically validated nutritional…
- Trial name
- CHANGE (NCT01616563)
- Testing
- Dietary Intervention, Exercise Prescription and Fitness Program
- Where
- 3 sites in Canada
- Volunteers
- 305 people
- Sponsor
- Daren K. Heyland
Obesity
Study to Promote Weight Loss in Primary Care Practices
The purpose of this study is to determine if primary care based, telephone-delivered weight loss interventions are effective.
- Trial name
- NCT00749606
- Testing
- Individual telephone intervention, Group telephone intervention
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Obesity
BLOOM: Behavioral Modification and Lorcaserin for Overweight and Obesity Management
The purpose of this study is to assess the weight loss effect of lorcaserin at the end of the first year of treatment (Week 52) and to assess the ability of lorcaserin to maintain weight loss at the end of the second year of…
- Trial name
- NCT00395135
- Testing
- Lorcaserin 10 mg BID
- Where
- United States
- Volunteers
- 3,182 people
- Sponsor
- Eisai Inc.
Body Weight, Weight Change
Effect of Body Weight Change to Surgical ICU Outcomes
Aims of study 1. Effect of daily weight change upto 7 days from ICU admission to outcome of treatment in 28 days 2. Determination cut point of maximum weight change to outcome treatment
- Trial name
- NCT01351506
- Where
- Thailand
- Volunteers
- 465 people
- Sponsor
- Chiang Mai University
Weight Gain
Role of Peanuts in Healthy Weight Gain in Athletic Individuals
Many athletes and military personnel desire weight gain primarily as lean mass to improve performance and effectiveness in military/sport endeavors.
- Trial name
- mGAINS (NCT05426109)
- Testing
- Peanut snacks, No peanut-containing snacks
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Cardiovascular Disease, Childhood Obesity
PREVENT Tool Study: Late Effects Clinic
The purpose of this study is to test the feasibility of a novel, Health Information Technology behavior change tool in a single clinic setting.
- Trial name
- NCT04530825
- Testing
- Wait-List Control, PREVENT Tool
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Washington University School of Medicine
Pulmonary Disease, Chronic Obstructive, Obesity
INtervention Study In overweiGHT Patients With COPD
Symptoms of chronic obstructive pulmonary disease (COPD) and high body mass index (BMI) overlap. The investigators are trying to find out if a program proven to help people lose a modest amount of weight and increase their…
- Conditions
- Pulmonary Disease, Chronic Obstructive, Obesity, Weight Loss, Life Style
- Trial name
- INSIGHT COPD (NCT02634268)
- Testing
- Lifestyle Intervention
- Where
- 39 sites in United States
- Volunteers
- 684 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Diabetes Mellitus, Obesity
A Low-Carbohydrate, Ketogenic Diet Versus Orlistat for Weight Loss
This study compares two types of diet interventions: a low carbohydrate ketogenic diet (Atkins) and a low-fat diet combined with a medication (Orlistat).
- Trial name
- NCT00108524
- Testing
- Low carbohydrate ketogenic diet, Orlistat, Low-fat diet
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Obesity
A Study to Assess the Compliance and Impact on Weight of Kurbo, a Pediatric Centered Weight Loss App
Kurbo is a health and fitness app that is targeted toward the pediatric population. It utilizes games and activities to educate children about healthy eating, portion control/size and exercise.
- Trial name
- Kurbo (NCT02880254)
- Testing
- Kurbo, Personal Health Coach
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Baystate Medical Center
Obesity, Overweight
A Study of LY3437943 in Participants Who Have Obesity or Are Overweight
This is a study of LY3437943 in participants who have obesity or are overweight. The main purpose is to learn more about how LY3437943 affects body weight loss. The study will last about 18 months and may include up to 18 visits.
- Trial name
- NCT04881760
- Testing
- LY3437943
- Where
- 28 sites in United States, Puerto Rico
- Volunteers
- 338 people
- Sponsor
- Eli Lilly and Company
Weight Change, Body, Smoking Cessation
Efficacy of Two Novel Behavioral Post-cessation Weight Gain Interventions
The study aims to randomize 400 participants to 1 of 3 arms: a) a weight stability intervention prior to smoking cessation (Group 1); b) a weight loss intervention prior to smoking cessation (Group 2); or c) a self-guided weight…
- Trial name
- NCT03156660
- Testing
- Weight gain prevention (Group 1), Weight loss intervention (Group 2), Self-guided intervention (Group 3)
- Where
- United States
- Volunteers
- 305 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Obesity
MOWI Home-Based Pilot
The goal of this study is to conduct a program of pilot research aimed at developing and evaluating a technology-assisted wellness intervention for older adults with obesity.
- Trial name
- NCT03104205
- Testing
- Evaluate home-based MOWI
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Weight Loss, Diet, Healthy
Delicious Eating for Life in Southern Homes
This study will compare a new weight loss program that focuses on a healthy eating pattern, with WW™ (formally Weight Watchers), an effective and widely available weight loss program.
- Conditions
- Weight Loss, Diet, Healthy, Cardiovascular Risk Factor
- Trial name
- DELISH (NCT04302727)
- Testing
- Med-South Weight Loss Intervention, WW
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill