Clinical trials: Body Weight Change
Body Weight, Lipids
CCRC: Understanding the Effects of Omega-3 Fatty Acids Versus Lignans in Flaxseed on Metabolic and Inflammatory Markers Leading to Diabetes and Cardiovascular Disease
The aim of this study is to compare the effects of flaxseed on atherogenic lipids, plasma inflammatory markers, and insulin sensitivity.
- Conditions
- Body Weight, Lipids, Blood Glucose, Insulin
- Trial name
- NCT00935922
- Testing
- Flaxseed
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Obesity, Cardiovascular Disease
Gastric Sleeve Pilot Study in Morbidly Obese Undergoing Liver Transplantation
The rapid rise in obesity (body mass index (BMI) ≥ 30 kg/m2) in the US over the past decade is responsible for more disease and death than any other single factor.
- Conditions
- Obesity, Cardiovascular Disease, Type 2 Diabetes, Hypertension
- Trial name
- NCT02068872
- Testing
- Sleeve Gastrectomy
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Northwestern University
Nutrition, Cognitive Change
Effect of Morning Snack on Cognitive Performance in Adults
To characterize the effects of three chocolate snacks on cognitive performance, subjective appetite, food intake control, and glycemic response in normal weight adults.
- Conditions
- Nutrition, Cognitive Change, Food Intake Control, Satiety
- Trial name
- NCT03637829
- Testing
- Control, White chocolate, Dark chocolate 1
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Toronto Metropolitan University
Obesity
Comparison of Popular Weight Loss Diets
This study will compare the safety and effectiveness of three popular weight loss plans. These plans will be compared with the USDA Dietary Guidelines.
- Trial name
- NCT00079573
- Testing
- Atkins diet (extremely low carbohydrate), Zone diet (low carbohydrate, high protein), Ornish diet (very low fat)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Pediatric Obesity, Psychosocial Well-being
Childhood Obesity, Decided Not to Participate, Lifestyle Intervention and Psychosocial Well-being.
Childhood obesity has been associated with an increased risk of impaired psychosocial well-being and the development of depression and anxiety.
- Trial name
- NCT06705231
- Testing
- The Aarhus-intervention
- Where
- Denmark
- Volunteers
- 403 people
- Sponsor
- University of Aarhus
Healthy
Diets With a Spectrum of Fat Intake for Preventing Obesity: A Randomized Controlled-feeding Trial
The aim of the current study is to evaluate the effects of diets with three levels of dietary fat on weight change and related cardiometabolic risk factors in a 6-month randomized controlled-feeding trial.
- Trial name
- NCT02355795
- Testing
- low-fat diet, moderate-fat diet, high-fat diet
- Where
- China
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Obesity, Weight Gain
Diet, Physical Activity and Breastfeeding Intervention on Maternal Nutrition, Offspring Growth and Development
NCDs are observed mostly in adults, however there is strong evidence that suggests NCDs origin early in life, thus the first 1000 days of life (conception to age 2yrs).
- Conditions
- Obesity, Weight Gain, Metabolic Diseases, Birth Weight
- Trial name
- NCT01916603
- Testing
- Normative Intervention
- Where
- Chile
- Volunteers
- 2,400 people
- Sponsor
- University of Chile
Liver Cirrhosis, Obesity
Impact of Weight Loss in Cirrhosis With Obesity and MAFLD
Nutrition therapy is the cornerstone of medical therapy in patients with cirrhosis. 70% compensated patients with Chronic Liver Disease (CLD) are overweight or obese.
- Trial name
- WELCOME (NCT05104541)
- Testing
- Weight loss
- Where
- India
- Volunteers
- 96 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Obesity, Weight Loss
Comparison of Weight Loss Programs for Individuals With Severe Obesity
The purpose of this study is to evaluate the effectiveness of a technology-based system (the Body Media FIT system) for enhancing weight loss in severely obese individuals (BMI: ≥ 40 kg/m2).
- Trial name
- NCT01330329
- Testing
- Standard behavioral treatment, SBT + technology system (SBT+FIT)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- The Miriam Hospital
Cachexia; Cancer, Fecal Microbiota Transplantation (FMT)
Intestinal Microbiota Transplantation for Treating Advanced Tumor Cachexia
This project is a prospective, multicenter, single-arm, phase II clinical study aimed at evaluating the efficacy and safety of fecal microbiota transplantation (FMT) in treating advanced tumor cachexia.
- Trial name
- FMT-CACH (NCT07533227)
- Testing
- FMT capsule
- Volunteers
- 66 people
- Sponsor
- Hua Jiang
Obesity
Physical Fitness and Nutrition Intake in Bariatric Surgery Population
The purpose of this research study is to determine how bariatric surgery affects physical activity and nutrient intake. This research study is being done because the investigators want to determine better recommendations to…
- Trial name
- NCT02070354
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Geisinger Clinic
Weight Loss
Active Nutrition Program on Weight Loss
The study will evaluate the impact of the Active Nutrition 60-day program from USANA on weight loss and related measures, such as body composition, physical appearance/body shape, perceived wellness, and biochemical markers of…
- Trial name
- NCT06249698
- Testing
- meal replacements and supplements
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Memphis
Morbid Obesity, Metabolic Syndrome
Changes in Different Fat Compartments and Their Effect on Particular Manifestations of Metabolic Syndrome After Bariatric Procedures.
The metabolic risks associated with obesity are closely correlated with central (abdominal), rather than a peripheral (gluteofemoral) fat pattern It has been shown that weight loss after bariatric surgery is followed by metabolic…
- Conditions
- Morbid Obesity, Metabolic Syndrome, Visceral Obesity
- Trial name
- NCT00431587
- Where
- Israel
- Volunteers
- 1,000 people
- Sponsor
- Hadassah Medical Organization
Body Weight Changes
Pilot Study on the Impact of the Mediterranean Diet and Intermittent Fasting
This clinical trial attempts to evaluate the feasibility and acceptability of an intervention combining intermittent fasting and the Mediterranean diet guidelines vs an comparative intervention combining intermittent fasting but…
- Trial name
- NCT04185948
- Testing
- Mediterranean diet guidelines plus intermittent fasting, UK Eatwell guidelines plus intermittent fasting
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Overweight, Obesity
FirstWIND: Weight Loss Interventions After Delivery
This a pilot intervention study in which postpartum women will be randomized to receive a 6-month postpartum weight loss intervention or usual care.
- Trial name
- NCT00377026
- Testing
- lifestyle intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Johns Hopkins University
Weight Loss
Comparison of Two Workplace-Sponsored Obesity Prevention Programs
Obesity has reached epidemic proportions in the United States with nearly 64% of American adults considered overweight or obese.
- Trial name
- NCT00481715
- Testing
- Web-Based Weight Loss Program, Cash Incentive Weight Loss Program
- Volunteers
- 1,020 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Weight Loss
Oral VK2735 for Weight Management Phase 3 (SUNRISE 1)
This study is one of two planned Phase 3 studies to support the weight management indication for VK2735 Oral in obese (BMI ≥ 30 kg/m2) or overweight (BMI ≥ 27kg/m2) adults with at least one weight-related comorbidity without type…
- Trial name
- NCT07868835
- Testing
- VK2735
- Volunteers
- 560 people
- Sponsor
- Viking Therapeutics, Inc.
Respiratory Distress Syndrome, Preterm Birth
LISA vs INSURE in Extremely Low Birth Weight Infants. A Manikin Study
This is an unblinded, randomized, controlled, crossover (AB/BA) trial of surfactant treatment with LISA vs. INSURE in a manikin simulating an extremely low birth weight infant.
- Conditions
- Respiratory Distress Syndrome, Preterm Birth, Surfactant Deficiency Syndrome Neonatal
- Trial name
- NCT04944108
- Testing
- LISA approach, Insure approach
- Where
- 2 sites in Italy
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University Hospital Padova
Dehydration, Weight Loss
Effect of Dehydration on Sleep Quality, Cognitive Skills, and Electromyographic Responses in Combat Athletes
This study examines the effects of rapid dehydration-induced weight loss on combat athletes' sleep quality, cognitive skills, and isokinetic strength performance.
- Conditions
- Dehydration, Weight Loss, Weight Cycling, Sleep
- Trial name
- NCT07118904
- Testing
- Rapid weight loss through dehydration
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Obesity
Can Genetic Markers Predict Weight Loss After Gastric By-pass Surgery
There is a variability in weight loss after gastric bypass surgery for obesity despite a standardised surgical procedure. This study aims to investigate if genetic markers can predict outcome after gastric by-pass surgery in…
- Trial name
- NCT01736384
- Testing
- Gastric bypass or cholecystectomy
- Where
- 3 sites in Sweden
- Volunteers
- 2,000 people
- Sponsor
- Karolinska Institutet