Clinical trials: Body Weight Change
Weight Loss
Feasibility of a Campaign Intervention Compared to a Standard Behavioral Weight Loss Intervention in Overweight and Obese Adults
The purpose of this study is to examine the feasibility of a campaign intervention for weight management compared to a standard behavioral weight loss intervention in overweight and obese adults.
- Trial name
- NCT01803737
- Testing
- Standard Behavioral Weight Loss Intervention (SBWL), Campaign Intervention (CI)
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Pittsburgh
Osteoarthritis, Knee, Osteoarthritis, Hip
OA Clinic-Community CARE Model
The purpose of this study is to test the OA Clinic-Community CARE Model (OA CARE) which will address all recommended components of knee/hip (osteoarthritis) OA care, include interventions for both patients and primary care…
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Overweight, Obesity
- Trial name
- OA CARE (NCT05349500)
- Testing
- OA CARE Intervention, Usual Care control group
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of North Carolina, Chapel Hill
Postpartum Weight Retention
Laser Acupuncture for Postpartum Weight Retention
Objective: To determine the therapeutic effect of acupuncture on postpartum weight retention. Methods: 66 subjects after delivery with postpartum weight retention will be randomly divided into laser acupuncture and control group.
- Trial name
- NCT02840916
- Testing
- laser acupuncture
- Where
- Taiwan
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Obesity, Overweight
A Safety and Efficacy Study of Naltrexone SR/Bupropion SR and Placebo in Overweight and Obese Subjects Participating in an Intensive Behavior Modification Program
The purpose of this study is to determine whether a combination of naltrexone SR and bupropion SR is safe and effective in treating obesity and leads to greater weight loss when given with a group lifestyle modification program…
- Trial name
- NCT00456521
- Testing
- Naltrexone SR 32 mg/ bupropion SR 360 mg/ day, Intensive group lifestyle modification counseling
- Where
- 9 sites in United States
- Volunteers
- 793 people
- Sponsor
- Orexigen Therapeutics, Inc
Weight Loss, Appetite Loss
Role of Transcranial Direct Current Stimulation in Appetite and Weight Control
To study the effects of transcranial direct current stimulation (tDCS) on weight and appetite.
- Trial name
- TDCS (NCT05609604)
- Testing
- tDCS
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University at Buffalo
Malnutrition, Wasting
Nutritional Impact of Moringa Oleifera Leaf Supplementation in Mothers and Children
Studies to date on the effects of Moringa oleifera in diabetes and anemia and animal studies that examine the utility of moringa for increased milk and litter yield are of small scale, however high-quality large-scale placebo or…
- Conditions
- Malnutrition, Wasting, Growth Failure
- Trial name
- NCT04587271
- Testing
- Moringa oleifera (high dose), Moringa oleifera (low dose)
- Where
- 2 sites in Kenya
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Suzanna L Attia
Hypercatabolic Status Related to Severe Burn
Study of Tolerability and Efficacy of BVS857 in Severe Burn Subjects
Study of tolerability and efficacy of BVS857 in severe burn subjects over 8 weeks and 15 weeks
- Trial name
- NCT02074995
- Testing
- BVS857
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Novartis Pharmaceuticals
Pediatric Obesity
Adapting Diet and Action for Everyone (ADAPT+)
The purpose of this study is to refine and optimize an obesity intervention with rural underserved Latino children and their parents that combines a standard family-based behavioral approach, the "gold standard" for pediatric…
- Trial name
- ADAPT+ (NCT04800432)
- Testing
- ADAPT+, EUC
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Hypothalamic Obesity
Energy Balance & Weight Loss in Craniopharyngioma-related or Other Hypothalamic Tumors in Hypothalamic Obesity
The proposed multicenter study will test the effect of glucagon-like peptide (GLP)-1 agonist exenatide once weekly extended-release (ExQW, Bydureon®) on clinical outcomes and metabolic parameters in a double-blind…
- Trial name
- ECHO (NCT02664441)
- Testing
- Exenatide
- Where
- 3 sites in United States
- Volunteers
- 42 people
- Sponsor
- Seattle Children's Hospital
Healthy
Bioenergetic Alterations After Exenatide Administration
The purpose of this study is to find out how exenatide causes weight loss. Specifically, the study is assessing how exenatide may change how people take in energy (energy intake), as well as how it may effect how people use…
- Trial name
- NCT00623545
- Testing
- Exenatide
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Obesity
Coaching Veterans to Healthy Weights and Wellness
ASPIRE has completed enrollment of patients at the Ann Arbor and Cleveland Medical Centers in a study that is examining the impact of an innovative approach to weight loss ("Aspiring to Lifelong Health in VA", aka "ASPIRE-VA").
- Trial name
- ASPIRE (NCT00967668)
- Testing
- Small change approach to improve physical activity and diet, MOVE! Usual Care
- Where
- 2 sites in United States
- Volunteers
- 481 people
- Sponsor
- US Department of Veterans Affairs
Breast Neoplasms
Reach for Health Study: Obesity-related Mechanisms and Mortality in Breast Cancer Survivors
This objective of this randomized controlled trial is to conduct a 2x2 test of a lifestyle intervention and metformin (a drug used to treat diabetes) to investigate how these treatments, alone or in combination, affect biomarkers…
- Trial name
- NCT01302379
- Testing
- Metformin, Lifestyle intervention, Standard printed dietary guidelines
- Where
- United States
- Volunteers
- 333 people
- Sponsor
- University of California, San Diego
Obesity
Multivitamin Adherence Following Bariatric Surgery
Additional micronutrient supplementation is required due to the changes in the gastrointestinal anatomy and physiology following bariatric surgery along with decreased dietary intake and rapid weight loss.
- Trial name
- NCT02124889
- Testing
- Weekly Internet surveys
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Wake Forest University Health Sciences
Obesity
The Effects of Oxytocin in Obese Adults
This is a randomized, double blind, placebo-controlled study of the effects of intranasal oxytocin in obese adults, ages 18-45 years old.
- Trial name
- NCT03043053
- Testing
- oxytocin nasal spray
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Massachusetts General Hospital
Weight Loss, Weight Gain
Eating Mindfully to Prevent Weight Regain
The overall objective of this study is to evaluate the efficacy of a mindfulness-based intervention to prevent weight regain in weight-reduced adults.
- Conditions
- Weight Loss, Weight Gain, Eating Behavior, Obesity
- Trial name
- EMPWR (NCT04847843)
- Testing
- Mindfulness Orientated Recovery Enhancement, Control Intervention
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Utah
Obesity
Use of Medication to Improve Weight Loss in Suboptimal Early Responders to Behavioral Treatment
This is a two-phase study. Phase 1 will evaluate obesity-related behavioral and biological characteristics as potential predictors of response to behavioral treatment (BT) for weight loss.
- Trial name
- NCT03779048
- Testing
- Behavioral Treatment, Phentermine 15 MG
- Where
- United States
- Volunteers
- 147 people
- Sponsor
- University of Pennsylvania
Melanoma
Palonosetron for Prevention of Biochemotherapy Induced Nausea and Vomiting
Primary Objectives: Safety of palonosetron administered for control of nausea and vomiting in patients with metastatic melanoma receiving biochemotherapy.
- Trial name
- NCT00412425
- Testing
- Palonosetron
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- M.D. Anderson Cancer Center
Obesity, Overweight
A Study to Evaluate the Change in Weight After 24 Weeks Treatment With LIK066 in Obese or Overweight Adults
This was a dose-finding study that evaluated the change in weight after 24 weeks treatment with 8 different doses of LIK066 compared to placebo in obese or overweight adults, followed by 24 weeks treatment with 2 doses of LIK066…
- Trial name
- NCT03100058
- Testing
- LIK066
- Where
- 83 sites in United States, Austria and 5 more
- Volunteers
- 460 people
- Sponsor
- Novartis Pharmaceuticals
Diabetes, Effects of Liraglutide Administration on Brain Activity
Liraglutide in Obesity and Diabetes: Identification of CNS Targets Using fMRI
The main purpose of this study is to help us understand the effects of diabetes medication Liraglutide on weight loss and hunger.
- Conditions
- Diabetes, Effects of Liraglutide Administration on Brain Activity, Weight Loss, Hunger
- Trial name
- NCT01562678
- Testing
- Liraglutide
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Beth Israel Deaconess Medical Center
Obesity, Overweight
Effectiveness Between Nutritional Counseling Monthly Phone Call Versus Self Help Informative Booklet
The purpose of this study is to evaluate the most effectiveness between a personalized nutritional program with a counseling monthly phone call Versus personalized nutritional program with self help Informative Booklet in a group…
- Trial name
- NCT01602965
- Testing
- Counseling Monthly Phone Calls, Self Help Informative Booklet
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Istituto Ortopedico Rizzoli