Clinical trials: Body Weight Changes
Obesity, Weight Gain
Diet, Physical Activity and Breastfeeding Intervention on Maternal Nutrition, Offspring Growth and Development
NCDs are observed mostly in adults, however there is strong evidence that suggests NCDs origin early in life, thus the first 1000 days of life (conception to age 2yrs).
- Conditions
- Obesity, Weight Gain, Metabolic Diseases, Birth Weight
- Trial name
- NCT01916603
- Testing
- Normative Intervention
- Where
- Chile
- Volunteers
- 2,400 people
- Sponsor
- University of Chile
Liver Cirrhosis, Obesity
Impact of Weight Loss in Cirrhosis With Obesity and MAFLD
Nutrition therapy is the cornerstone of medical therapy in patients with cirrhosis. 70% compensated patients with Chronic Liver Disease (CLD) are overweight or obese.
- Trial name
- WELCOME (NCT05104541)
- Testing
- Weight loss
- Where
- India
- Volunteers
- 96 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Obesity, Weight Loss
Comparison of Weight Loss Programs for Individuals With Severe Obesity
The purpose of this study is to evaluate the effectiveness of a technology-based system (the Body Media FIT system) for enhancing weight loss in severely obese individuals (BMI: ≥ 40 kg/m2).
- Trial name
- NCT01330329
- Testing
- Standard behavioral treatment, SBT + technology system (SBT+FIT)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- The Miriam Hospital
Cachexia; Cancer, Fecal Microbiota Transplantation (FMT)
Intestinal Microbiota Transplantation for Treating Advanced Tumor Cachexia
This project is a prospective, multicenter, single-arm, phase II clinical study aimed at evaluating the efficacy and safety of fecal microbiota transplantation (FMT) in treating advanced tumor cachexia.
- Trial name
- FMT-CACH (NCT07533227)
- Testing
- FMT capsule
- Volunteers
- 66 people
- Sponsor
- Hua Jiang
Obesity
Physical Fitness and Nutrition Intake in Bariatric Surgery Population
The purpose of this research study is to determine how bariatric surgery affects physical activity and nutrient intake. This research study is being done because the investigators want to determine better recommendations to…
- Trial name
- NCT02070354
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Geisinger Clinic
Weight Loss
Active Nutrition Program on Weight Loss
The study will evaluate the impact of the Active Nutrition 60-day program from USANA on weight loss and related measures, such as body composition, physical appearance/body shape, perceived wellness, and biochemical markers of…
- Trial name
- NCT06249698
- Testing
- meal replacements and supplements
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Memphis
Morbid Obesity, Metabolic Syndrome
Changes in Different Fat Compartments and Their Effect on Particular Manifestations of Metabolic Syndrome After Bariatric Procedures.
The metabolic risks associated with obesity are closely correlated with central (abdominal), rather than a peripheral (gluteofemoral) fat pattern It has been shown that weight loss after bariatric surgery is followed by metabolic…
- Conditions
- Morbid Obesity, Metabolic Syndrome, Visceral Obesity
- Trial name
- NCT00431587
- Where
- Israel
- Volunteers
- 1,000 people
- Sponsor
- Hadassah Medical Organization
Body Weight Changes
Pilot Study on the Impact of the Mediterranean Diet and Intermittent Fasting
This clinical trial attempts to evaluate the feasibility and acceptability of an intervention combining intermittent fasting and the Mediterranean diet guidelines vs an comparative intervention combining intermittent fasting but…
- Trial name
- NCT04185948
- Testing
- Mediterranean diet guidelines plus intermittent fasting, UK Eatwell guidelines plus intermittent fasting
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Overweight, Obesity
FirstWIND: Weight Loss Interventions After Delivery
This a pilot intervention study in which postpartum women will be randomized to receive a 6-month postpartum weight loss intervention or usual care.
- Trial name
- NCT00377026
- Testing
- lifestyle intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Johns Hopkins University
Weight Loss
Comparison of Two Workplace-Sponsored Obesity Prevention Programs
Obesity has reached epidemic proportions in the United States with nearly 64% of American adults considered overweight or obese.
- Trial name
- NCT00481715
- Testing
- Web-Based Weight Loss Program, Cash Incentive Weight Loss Program
- Volunteers
- 1,020 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Weight Loss
Oral VK2735 for Weight Management Phase 3 (SUNRISE 1)
This study is one of two planned Phase 3 studies to support the weight management indication for VK2735 Oral in obese (BMI ≥ 30 kg/m2) or overweight (BMI ≥ 27kg/m2) adults with at least one weight-related comorbidity without type…
- Trial name
- NCT07868835
- Testing
- VK2735
- Volunteers
- 560 people
- Sponsor
- Viking Therapeutics, Inc.
Dehydration, Weight Loss
Effect of Dehydration on Sleep Quality, Cognitive Skills, and Electromyographic Responses in Combat Athletes
This study examines the effects of rapid dehydration-induced weight loss on combat athletes' sleep quality, cognitive skills, and isokinetic strength performance.
- Conditions
- Dehydration, Weight Loss, Weight Cycling, Sleep
- Trial name
- NCT07118904
- Testing
- Rapid weight loss through dehydration
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Obesity
Can Genetic Markers Predict Weight Loss After Gastric By-pass Surgery
There is a variability in weight loss after gastric bypass surgery for obesity despite a standardised surgical procedure. This study aims to investigate if genetic markers can predict outcome after gastric by-pass surgery in…
- Trial name
- NCT01736384
- Testing
- Gastric bypass or cholecystectomy
- Where
- 3 sites in Sweden
- Volunteers
- 2,000 people
- Sponsor
- Karolinska Institutet
Weight Loss, Weight Gain
Effect of Ready to Use Therapeutic Food (RUTF) Supplement After an Episode of Malaria Falciparum on Weight
The primary objective of this study is to determine to what extent provision with RUTF will promote catch up growth in children following an acute uncomplicated episode of P. falciparum malaria.
- Conditions
- Weight Loss, Weight Gain, Convalescence, Malaria
- Trial name
- NCT00819858
- Testing
- RUTF (Plumpynut®)
- Where
- Republic of the Congo
- Volunteers
- 180 people
- Sponsor
- Medecins Sans Frontieres, Netherlands
Obesity
A Study to Examine the Effect of Pramlintide on Body Weight and Its Safety and Tolerability in Obese Subjects
This is a study to examine the effect of pramlintide on body weight and its safety and tolerability in obese subjects.
- Trial name
- NCT00112021
- Testing
- pramlintide acetate
- Where
- 21 sites in United States
- Volunteers
- 400 people
- Sponsor
- AstraZeneca
Obesity & Overweight
Changes in Intestinal Permeability and Systemic Inflammation Following Fast Food Overfeeding.
The purpose of this study is to investigate whether lifestyle factors can alter gut barrier integrity and whether disruptions of the gut barrier can trigger systemic and tissue-specific inflammation.
- Trial name
- ChIPS (NCT07893743)
- Testing
- Fast-food overfeeding
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Nutritional and Metabolic Diseases, Child Obesity
The FibreGum Study - Changing the Course of Obesity in Children
The aim of this study is thus to assess the effect of a chewing gum containing fibres on body weight, metabolism and the oral and intestinal microbiomes in a population of obese children.
- Conditions
- Nutritional and Metabolic Diseases, Child Obesity, Adolescent Obesity
- Trial name
- FibreGum (NCT05540678)
- Testing
- FibreGum
- Where
- 2 sites in Switzerland
- Volunteers
- 93 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Obesity
A Controlled-Study on the Effect of a Combination of Fenofibrate and Metformin on Weight Loss and Weight Loss-Maintenance, in Obese Patients.
To investigate the effect on body weight of a combination fenofibrate and metformin on top of a moderate balanced calorie-deficit diet.
- Trial name
- NCT00349635
- Testing
- Metformin and Metformin + Fenofibrate
- Where
- 3 sites in Finland
- Volunteers
- 148 people
- Sponsor
- Solvay Pharmaceuticals
Obesity, Diet Modification
Efficacy of Balanced Nutrition Meal Replacement Along With a Caloric Restriction on Body Weight Control
The present study was designed to evaluate the impact of a nutritionally balanced conventional meal replacement diet with caloric restriction (intervention for 8 weeks) in Taiwanese obese subjects.
- Conditions
- Obesity, Diet Modification, Nutrient; Excess
- Trial name
- nutrition (NCT03642925)
- Testing
- Meal replacement diet
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Obesity, Oxidative Stress
Investigations of Botanicals on Food Intake, Satiety, Weight Loss, and Oxidative Stress
Despite widespread efforts to improve the treatment of obesity, only limited progress has been made. Calorie restriction (CR) has consistently been shown to produce weight loss, as well as delay the onset of age-related diseases…
- Trial name
- NCT01238887
- Testing
- Garcinia cambogia-derived hydroxycitric acid (2800 mg/day), Garcinia Cambogia derived Hydroxycitric Acid
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Florida