Clinical trials: Body Weight Control
Abdominal Obesity
Effect of Ultrasound Cavitation Versus Whole Body Vibration on Abdominal Fat in Obese Adolescent Females
This study aims to determine the differences between the effect of ultrasound cavitation and whole-body vibration on abdominal fat in obese adolescent females
- Trial name
- NCT06529211
- Testing
- Low caloric diet, Ultrasound cavitation, Whole body vibration
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Nausea, Vomiting
Decreasing the Incidence of Post-Operative Nausea and Vomiting (PONV) in Bariatric Patients
The study drug, Aprepitant, is currently used to control chemotherapy induced nausea and vomiting and is also approved for post-operative nausea and vomiting.
- Trial name
- PONV (NCT00956215)
- Testing
- Aprepitant
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- University of Pennsylvania
Type2 Diabetes, Overweight and Obesity
Virtual Weight Control Program Tailored for Adults With Type 2 Diabetes (VITAL)
The purpose of the study is to evaluate the effect of the WW program on people with Type 2 diabetes and the effect on glycemic control.
- Trial name
- VITAL (NCT04804774)
- Testing
- WW program modified for people with Type 2 diabetes
- Where
- 3 sites in United States
- Volunteers
- 136 people
- Sponsor
- Pennington Biomedical Research Center
Obesity
WE Project: 2.0 Grassroots Wellness Coaching (Phase 2)
African American adults that live in economically disadvantaged areas are at an increased risk for obesity and cardiometabolic disease.
- Trial name
- NCT06172582
- Testing
- 12-week lifestyle intervention
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Weight Gain, Disorder of Bone Density and Structure, Unspecified
Drug Exposure and Depot Medroxyprogesterone Acetate (DMPA) in Adolescent Subjects
The investigators are doing this study to look at how different doses of the Depot medroxyprogesterone acetate (DMPA) shot effect weight gain and bone mineral density in teens.
- Conditions
- Weight Gain, Disorder of Bone Density and Structure, Unspecified, Uterine Bleeding
- Trial name
- NCT01461824
- Testing
- Depot medroxyprogesterone acetate (DMPA)
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Childhood Obesity
The Healthy Lifestyles Passport Program: a Nutrition Education Program to Prevent Childhood Obesity
The purpose of this study is to evaluate the effectiveness of the Healthy Lifestyles Passport Program (HLPP) in preventing infant and childhood obesity.
- Trial name
- HLPP (NCT01649115)
- Testing
- Healthy Lifestyles Passport
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Bronx-Lebanon Hospital Center Health Care System
Hypoxia, Hysteroscopy
The Effects of Remimazolam on the Incidence of Severe Hypoxia During Sedated Hysteroscopy for Assisted Reproduction in Overweight or Obese Patients
Hypoxia is a common adverse event during sedated hysteroscopy for assisted reproduction, and it is more likely to occur in overweight or obese patients.
- Conditions
- Hypoxia, Hysteroscopy, Overweight or Obesity
- Trial name
- RP (NCT06187896)
- Testing
- remimazolam, Propofol
- Where
- China
- Volunteers
- 600 people
- Sponsor
- RenJi Hospital
Obesity & Overweight
Effects of a 12-Week Individualized Energy-Restricted Diet on Perceived Stress and Serum Cortisol in Adults With Overweight or Obesity
This prospective interventional study investigated changes in perceived stress, serum cortisol concentrations, body weight, and body composition during a 12-week individualized energy-restricted dietary intervention in adults…
- Trial name
- NCT07873762
- Testing
- Energy-Restricted Mediterranean-Style Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Acibadem University
Heart Diseases, Stroke
The HARMONY Study: A Intervention to Reduce Cardiometabolic Risk in African American Women
This study will test whether a culturally-tailored nutrition and exercise intervention designed for African-American women will lead to sustained improvements in exercise and healthy eating through improvements in self-management…
- Conditions
- Heart Diseases, Stroke, Pre-diabetes, Hypertension
- Trial name
- NCT04705779
- Testing
- HARMONY, Nutrition and Exercise Education (NEEW)
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- University of North Carolina, Chapel Hill
Obesity & Overweight, Healthcare Worker
Personalized Nutrition Coaching for a Weight Loss Program Among Overweight and Obese Nurses
Obesity among healthcare workers has become an increasing public health concern, with potential consequences for work productivity, quality of care, and long-term health outcomes.
- Conditions
- Obesity & Overweight, Healthcare Worker, Low Physical Activity Level
- Trial name
- NCT07440979
- Testing
- Personalized Nutrition Coaching
- Where
- Indonesia
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universitas Padjadjaran
Obesity &Amp; Overweight
Soup and Bread Recipe Impacts on Ingestive Behavior
The goal of the study is to determine the likability of seeds incorporated into lunch foods. The study will provide a better understanding of ways to make recipe alterations that may promote health and fullness.
- Trial name
- NCT07146958
- Testing
- Chia seeds, Hemp seeds
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- USDA Beltsville Human Nutrition Research Center
Adults With Overweight/Obesity and Type 2 Diabetes
A Study to Assess the Efficacy, Safety and Tolerability of AT673 Co-administered With Semaglutide in Adult Participants With Type 2 Diabetes (T2D) and Overweight or Obesity
The goal of this clinical trial is to learn if AT673 contributes to additional weight loss and glycemic control when given with semaglutide in participants with overweight/obesity and type 2 diabetes.
- Trial name
- NCT07724340
- Testing
- AT673 low dose, AT673 high dose
- Where
- 8 sites in United States
- Volunteers
- 150 people
- Sponsor
- Antag Therapeutics
Childhood Obesity
Efficacy of an Educational School-based Intervention to Reduce Prevalence of Obesity in Childhood-EdAl-2
Our hypothesis is that a regular systematic educational intervention in primary school improves lifestyle choices and reduces obesity.
- Trial name
- EDAL2 (NCT01362023)
- Testing
- lifestyle counseling
- Where
- Spain
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Chronic Obstructive Pulmonary Disease (COPD) With Cachexia
BYM338 in Chronic Obstructive Pulmonary Disease (COPD) Patients With Cachexia
This study will assess the pharmacodynamics, pharmacokinetics, safety and tolerability of BYM338 in patients with COPD and cachexia. The primary outcome will be a change in thigh muscle volume compared to placebo.
- Trial name
- NCT01669174
- Testing
- BYM338
- Where
- 9 sites in United States, Netherlands and 1 more
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Overweight, Obese
iStart Smart for Teens for Healthy Weight Management
The emerging epidemic of type 2 diabetes mellitus (T2DM) in children is coupled with the increased prevalence of childhood obesity in the last two decades.
- Trial name
- NCT01693250
- Testing
- fitbit Ultra, Pedometer
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Overweight , Obesity
A Study of SRSD384 in Overweight or Obese Participants
This is a two-part study, intended to investigate the safety, tolerability, characteristics of PK and PD of single SC dose of SRSD384 alone in overweight or obese participants (Part A) and in combination with tirzepatide in…
- Trial name
- NCT07557355
- Testing
- SRSD384 injection
- Where
- Australia
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Sirius Therapeutics Co., Ltd.
Venous Thromboembolism, Deep Vein Thrombosis
RIVAroxaban Versus Low-molecular Weight Heparin in Patients With Lower Limb Trauma Requiring Brace or CASTing
Lower limb trauma requiring immobilization is a very frequent condition that is associated with an increased risk of developing venous thromboembolism (VTE).
- Conditions
- Venous Thromboembolism, Deep Vein Thrombosis, Pulmonary Embolism, Lower Limb Trauma
- Trial name
- RIVACAST (NCT06195540)
- Testing
- Rivaroxaban 10 MG, Low Heparin Molecular Weight
- Where
- 37 sites in France
- Volunteers
- 1,424 people
- Sponsor
- University Hospital, Angers
Obesity and Obesity-related Medical Conditions
Management of Obese Patients With Gastroesophageal Reflux Disease .
The aim of this study is to evaluate the efficacy Sleeve gastrectomy with cruroplasty with or without ligamentum teres wrapping for management of morbidly obese patients with concomitant reflux symptoms.
- Trial name
- NCT06599489
- Testing
- surgery ..operation
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hossam Mahmoud Ibrahim
PreDiabetes, Prediabetic State
Use of Empagliflozin to Treat Prediabetes
The overall purpose of this study is to identify how empagliflozin (a drug commonly used to treat type 2 diabetes) impacts skeletal muscle metabolic health among adults with prediabetes.
- Conditions
- PreDiabetes, Prediabetic State, Overweight and Obesity
- Trial name
- NCT05426525
- Testing
- Empagliflozin
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Oregon State University
Bariatric Surgery Candidate, Obesity
A Preoperative Cognitive Behavioural Therapy Program Based on Self-determination Theory for Bariatric Surgery Candidates
The objective of this study is to evaluate the impact of a pre-surgical intervention program based on Cognitive and Behavioural Emotional Therapies, on the degree of dietary restriction of patients who are candidates for…
- Trial name
- ACRoBAT (NCT03976674)
- Testing
- Cognitive Behavioural Therapy (CBT)
- Where
- France
- Volunteers
- 94 people
- Sponsor
- Lille Catholic University
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