Clinical trials: Body Weight Control
Obesity, Overweight
A Study of Weekly Oral Dose of Ecnoglutide (VRB-101) for Weight Maintenance in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities
The purpose of this study is to identify the weekly oral dose of VRB-101 (oral ecnoglutide) that can effectively maintain body weight in participants with a history of obesity or overweight with weight-related comorbidities.
- Conditions
- Obesity, Overweight, Weight Maintenance
- Trial name
- NCT07553299
- Testing
- VRB-101
- Where
- 20 sites in United States
- Volunteers
- 8 people
- Sponsor
- Verdiva Bio Dev Limited
Overweight and/or Obesity, Weight Management
A Phase Ib/IIa Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral Ecnoglutide Tablets in Chinese Participants With Overweight or Obesity
The aim of the study is to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of oral ecnoglutide tablets in Chinese participants with overweight or obesity
- Trial name
- NCT07243171
- Testing
- ecnoglutide tablets
- Where
- China
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Hangzhou Sciwind Biosciences Co., Ltd.
Type2 Diabetes Mellitus
Investigate the Efficacy and Safety of Low-Glu in Patients Newly Diagnosed With Type II Diabetes Mellitus
Ficus deltoidea leaves, Cinnamomum cassia and Black seed powdered extract have long been used for the treatment of type 2 diabetes mellitus.
- Trial name
- NCT05343767
- Testing
- Natural Wellness Low-Glu low dose, Natural Wellness Low-Glu high dose, Metformin
- Where
- Egypt
- Volunteers
- 198 people
- Sponsor
- Natural Wellness Egypt
Obesity, Cardiovascular Diseases
Worksite Program to Prevent Weight Gain Among Bus Drivers
The purpose of this study is to implement and evaluate a two-year multi-component environmental intervention to prevent weight gain among city bus drivers at four bus garages.
- Conditions
- Obesity, Cardiovascular Diseases, Heart Diseases
- Trial name
- NCT00122993
- Testing
- Healthful eating and food choices behavior change programs and changes in worksite food availability and prices, Physical Activity, Environment
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- University of Minnesota
Metabolic Health, Weight Loss
A Study to Evaluate the Effect of SlimBiotics Probiotic Formula on Weight Management and Metabolic Health Outcomes
This study is to evaluate the efficacy of a probiotic supplement on weight management and metabolic health. This study will be conducted as a hybrid trial consisting of both in-person visits and virtual assessments.
- Conditions
- Metabolic Health, Weight Loss, Stress, Well-Being, Psychological
- Trial name
- NCT05917314
- Testing
- Slimbiotic Probiotic
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Slimbiotics
Diabetes
A Study to Assess CT-868 and the Relationship Between Insulin Secretory Response and Ambient Blood Glucose
A Study to Assess the Effect of CT-868 and the Relationship Between Insulin Secretory Response and Ambient Blood Glucose in Obese Male Subjects and Subjects with T2DM.
- Trial name
- NCT04973111
- Testing
- CT-868 as SC Injection, Active Comparator as SC Injection
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Carmot Therapeutics, Inc.
Hypertension, Type 2 Diabetes
Lifestyle Intervention in Primary Health Care - the Björknäs Study
The purpose of this study is to determine whether a short group intervention programe aiming at lifestyle changes at a local health centre can improve risk factors for cardiovascular disease
- Conditions
- Hypertension, Type 2 Diabetes, Obesity, Dyslipidemia
- Trial name
- NCT00486941
- Testing
- Exercise and diet - based on DPS and DPP
- Where
- Sweden
- Volunteers
- 151 people
- Sponsor
- Umeå University
Type 2 Diabetes
The Effect of Personalized Nutrition on Changes in Metabolic Parameters in Patients With Type 2 Diabetes Mellitus
Type 2 diabetes mellitus (T2DM) is a multifactorial metabolic disorder commonly accompanied by obesity, hypertension, and suboptimal glycemic control, which together increase cardiovascular risk.
- Trial name
- NCT07696013
- Testing
- Personalized Nutrition, Generalized Nutrition
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- DINA KEUMALA SARI
Obesity, Abdominal
Effect of the Consumption of an Enriched Surimi in Abdominal Visceral Adiposity
The finding that the combination of the inactivated probiotic Bifidobacterium Lactis (BPL1), inulin as a source of soluble fiber and omega-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), in a surimi…
- Trial name
- NCT03630588
- Testing
- Surimi intervention
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Technological Centre of Nutrition and Health, Spain
Diabetes, Hypertension
Impact of Intermittent Fasting and Mediterranean Diet on the Physical Health of the Elderly
The prevalence of chronic diseases is increasing globally. In recent years, intermittent fasting has emerged as an effective dietary pattern against some of the most common chronic diseases in the elderly, alongside the…
- Conditions
- Diabetes, Hypertension, Dyslipidemias, Obesity
- Trial name
- FASTMED (NCT06480669)
- Testing
- Time Restricted Feeding, Mediterranean Diet
- Where
- Spain
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Type 2 Diabetes, Overweight and Obese Adults
Effects of D-Chiro-Inositol Combined with Metformin on Insulin Resistance in People with Overweight or Obesity and T2DM
This study evaluates the efficacy of D-Chiro-Inositol (DCI) as an add-on therapy to metformin in improving insulin resistance, measured by the HOMA index, in people with overweight or obesity and type 2 diabetes mellitus (T2DM).
- Trial name
- DIACHIRO (NCT06860841)
- Testing
- D-Chiro-Inositol Combined with Metformin
- Where
- Italy
- Volunteers
- 16 people
- Sponsor
- Campus Bio-Medico University
Obesity
A Study to Evaluate the Efficacy and Safety of PF-06882961 in Adults With Obesity
The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called PF-06882961) for the potential treatment of obesity.
- Trial name
- NCT04707313
- Testing
- PF-06882961 (Cohorts 1 and 2), PF-06882961 (Cohort 3)
- Where
- 41 sites in United States, Canada and 2 more
- Volunteers
- 628 people
- Sponsor
- Pfizer
Overweight , Obesity
A Trial to Examine the Effects of a Weight Loss Program Emphasizing Protein, Dietary Fiber, and Exercise (30-30-30 Plan)
The purpose of this study is to learn whether following an online weight loss program with specific dietary and exercise goals (the 30-30-30 plan) can help improve weight loss and other markers of health when compared to an…
- Trial name
- NCT07789769
- Testing
- 30-30-30 PFE Intervention, Standard
- Where
- 3 sites in United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Midwest Center for Metabolic and Cardiovascular Research
Obesity
A web-and Mobile Phone-based Intervention in 4-year-olds: a Population-based Randomized Controlled Trial
This study aims to evaluate the effects of a mobile phone-based dietary and physical activity intervention on body fatness, dietary intake and physical activity of preschoolers
- Trial name
- NCT02021786
- Testing
- Mobile phone based intervention
- Where
- Sweden
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Childhood Obesity, Child Obesity
Corestability Training in Overweight Children
A total of 52 overweight children aged between eight and sixteen years will be recruited by criterion based purposive sampling to participate in the two groups pretest post test randomized clinical study.
- Conditions
- Childhood Obesity, Child Obesity, Children, Only
- Trial name
- NCT04315220
- Testing
- Corestability training, No Intervention
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Asir John Samuel
Metabolic Syndrome, Pre-diabetes
Effect of Pasteurized Akkermansia Muciniphila on Insulin Resistance in Otherwise Healthy Subjects With Dysglycaemia
The purpose of this study is to demonstrate the efficacy of pasteurized Akkermansia muciniphila (pAKK) in improving insulin sensitivity in hyperglycaemic, but otherwise healthy persons with metabolic syndrome.
- Conditions
- Metabolic Syndrome, Pre-diabetes, Overweight and Obesity
- Trial name
- NCT05114018
- Testing
- Pasteurized A. muciniphila
- Where
- 2 sites in Germany, Ireland
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- A-Mansia Biotech S.A.
Diabetes Mellitus Type 2, Dyslipidemia
Low Calorie Diet and Diabetes
The primary hypothesis is to investigate whether a low calorie diet for 7 weeks followed by continuous lifestyle advice is an effective option to achieve an improvement in glucose control as measured by HbA1c after 52 and 104…
- Conditions
- Diabetes Mellitus Type 2, Dyslipidemia, Non-alcoholic Fatty Liver Disease, Obesity
- Trial name
- LCD (NCT02498990)
- Testing
- Low calorie diet followed by life style intervention
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska University Hospital
Type 2 Diabetes, Obesity
Efficacy, Safety, and Tolerability of CS0159 Combined With Semaglutide in MAFLD Patients With Obesity and T2DM
This is an exploratory study evaluating CS0159 in combination with Semaglutide in metabolic dysfunction-associated fatty liver disease (MAFLD) patients with obesity and type 2 diabetes (T2DM).
- Conditions
- Type 2 Diabetes, Obesity, Non-alcoholic Fatty Liver Disease
- Trial name
- NCT07570810
- Testing
- CS0159, Semaglutide
- Volunteers
- 30 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Obesity, Overweight
Smart Technology for Weight Loss and Metabolic Health
The study will evaluate whether a technology-based lifestyle intervention program using primarily a smartphone platform is an acceptable and effective way for treating obesity.
- Conditions
- Obesity, Overweight, Prediabetes, Weight Loss
- Trial name
- NCT02742662
- Testing
- Wearable technology, smartscale, Smartphone applications, Standard Weight Management Visits
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Temple University
T2DM (Type 2 Diabetes Mellitus), Hypertension
Virtual Diabetes Group Visits Across Health Systems
The purpose of this project is to evaluate the effectiveness of a virtual diabetes group visits on patients with type 2 diabetes mellitus (T2DM).
- Conditions
- T2DM (Type 2 Diabetes Mellitus), Hypertension, Heart Disease Chronic, Stroke
- Trial name
- VIDA (NCT06094491)
- Testing
- Virtual Group Visit
- Where
- 2 sites in United States
- Volunteers
- 720 people
- Sponsor
- University of Chicago
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.