Clinical trials: Body Weight Control
Obesity
A Study of Tirzepatide (LY3298176) Plus Mibavademab Compared With Tirzepatide Alone in Adult Participants With Obesity
The main purpose of this study is to determine if combining tirzepatide with mibavademab will result in more weight loss in adult participants than tirzepatide alone.
- Trial name
- NCT06373146
- Testing
- Tirzepatide, Mibavademab
- Where
- 17 sites in United States
- Volunteers
- 392 people
- Sponsor
- Eli Lilly and Company
Obesity & Overweight
Fuzzle System for Appetite Control and Weight Management
This study is evaluating whether the Fuzzle intraoral device can help adults with obesity lose weight when used alongside standard lifestyle counseling.
- Trial name
- NCT07527559
- Testing
- Fuzzle Intraoral Device, Lifestyle Management
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Fuzzle Operating Co.
Obesity
Evaluation of the Clinical Efficacy of Moxibustion With Regulating Yin and Yang in the Treatment of Menopausal Obesity
This study is designed as a two-dummy randomized controlled trial to evaluate the safety and superiority of Yin and Yang regulating moxibustion in the treatment of menopausal obese patients.
- Trial name
- NCT04943705
- Testing
- Yin and Yang Regulating Moxibustion
- Where
- 2 sites in China
- Volunteers
- 216 people
- Sponsor
- Hubei Hospital of Traditional Chinese Medicine
Obesity and Overweight
Kombucha in Overweight and Obese: Live Vs. Pasteurized Effects on Microbiota, Metabolism, and Liver Function
Kombucha, a fermented beverage made from Camellia sinensis tea (black, oolong, or green) with sugar and a symbiotic culture of bacteria and yeast (SCOBY), has gained global attention for its potential health benefits.
- Trial name
- KOMBIOME (NCT06759324)
- Testing
- Live kombucha (non filtered/ non pasteurized), Pasteurized kombucha (non filtered), Control (sparkling water)
- Where
- 2 sites in Portugal
- Volunteers
- 33 people
- Sponsor
- Associação Centro de Apoio Tecnológico Agro Alimentar
Obesity, Weight Loss
Longitudinal Effects of a Commercial Digital Weight Management Program on Weight Loss
This randomized controlled trial (RCT) will test how well a fully remote weight management program (Noom Weight) helps adults with overweight or obesity (BMI 25-45) achieve weight loss in both the short-term (16 weeks) and the…
- Trial name
- NCT06666842
- Testing
- Noom Weight, Educational Control
- Where
- United States
- Volunteers
- 412 people
- Sponsor
- Noom Inc.
Obesity, Morbid, Cesarean Section Complications
Traxi Panniculus Retractor for Cesarean Delivery
This prospective, open-label, randomized-controlled trial is designed to evaluate the use of the Traxi panniculus retractor-- a commercially available Class I FDA-exempt device will improve surgical outcomes, cardiopulmonary…
- Trial name
- NCT03651076
- Testing
- Traxi panniculus retraction (Clinical Innovations, LLC)
- Where
- 2 sites in United States
- Volunteers
- 142 people
- Sponsor
- Beth Israel Deaconess Medical Center
Covid19, Diabetes
Camostat and Artemisia Annua vs Placebo in COVID-19 Outpatients
This is a randomized, double-blind, placebo-controlled, multi-arm, multicenter, phase II trial design to allow a rapid efficacy and toxicity assessment of potential therapies (camostat mesilate and artemisia annua) immediately…
- Conditions
- Covid19, Diabetes, Hypertension, Obesity
- Trial name
- NCT04530617
- Testing
- Camostat Mesilate, Artemisia Annua Leaf
- Where
- Mexico
- Volunteers
- 246 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Eating Behavior, Healthy Diet
PROFRUVE Program to Promote Fruit and Vegetables Intake Among Children.
Because fruit and vegetables (FV) intake of children of Vitoria city is low, a controlled intervention program was proposed at school level.
- Conditions
- Eating Behavior, Healthy Diet, Fruit and Vegetable Intake, Childhood Obesity
- Trial name
- PROFRUVE (NCT03400891)
- Testing
- Program based on the theory of planned behaviour
- Volunteers
- 230 people
- Sponsor
- University of the Basque Country (UPV/EHU)
Obesity
Body Fat and Frequency of Resistance Training
This study compared different frequency low-volume resistance training (RT) on total, android, gynoid and trunk body fat in obese older women
- Trial name
- NCT03381976
- Testing
- Intervention 2X/week (G2X), Intervention 3X/week (G3X)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Londrina
Neonatal Hypoglycemia, Infant, Small for Gestational Age
Effect of Tahneek on Hypoglycemia in Newborn Infants
Tahneek is an Arabic word which means putting something sweet such as dates, in the infant's mouth after the birth. Neonatal hypoglycemia is common in the first few days after birth.
- Conditions
- Neonatal Hypoglycemia, Infant, Small for Gestational Age, Macrosomia, Fetal, Intrauterine Growth Restriction
- Trial name
- THIN (NCT03726697)
- Testing
- Tahneek
- Where
- Saudi Arabia
- Volunteers
- 324 people
- Sponsor
- King Abdullah International Medical Research Center
Normoglycemic, Normal Body Weight
A Study of the Effect of Oats on Post Prandial Glucose Response
The objectives are to assess the effects of high viscosity vs. medium and low viscosity oat β-glucan on post-prandial glycemic response in healthy adult participants.
- Trial name
- NCT02651597
- Testing
- Oatmeal
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Overweight, Obesity
The Weight-Wise Weight Loss Translation Study
The overall goal of the translational research is to evaluate the processes and outcomes of implementing, in a range of public health agencies, an intense, evidence-based behavioral weight loss intervention with demonstrated…
- Conditions
- Overweight, Obesity, Cardiovascular Disease
- Trial name
- Weight-Wise (NCT01141348)
- Testing
- Special Intervention, Delayed Intervention
- Where
- 6 sites in United States
- Volunteers
- 189 people
- Sponsor
- University of North Carolina, Chapel Hill
Obese and Metabolic Disorders
Safety and Pharmacokinetics of HRS-1597 Tablets in Healthy and Obese Participants: A Phase 1 Study
This is a Phase 1, single-center, randomized, double-blind, placebo-controlled study to evaluate the safety, tolerability, and pharmacokinetics of HRS-1597 tablets following single-dose administration in healthy participants and…
- Trial name
- NCT07808918
- Testing
- HRS-1597
- Where
- China
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Shandong Suncadia Medicine Co., Ltd.
Secondary Hypothyroidism, Hypopituitarism
Phase 4 Study in Secondary Hypothyroidism: Body Weight Adapted Thyroxin Treatment and Triiodothyronine Supplementation
The purpose of this study is to determine whether a body weight adjusted dose of thyroxin is superior to treatment guided by laboratory results of thyroxin hormones in patients with central hypothyroidism.
- Conditions
- Secondary Hypothyroidism, Hypopituitarism, Hyperlipidemias
- Trial name
- NCT00360074
- Testing
- Thyroxin, Triiodothyronine
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- University Hospital Freiburg
Overweight, Obesity
The Effect of a Multi-component Weight Management Program on Appetite, Food Preference and Body Weight
The aim of the current study is to demonstrate that a commercial weight management diet (i.e. low energy density) influences satiation, hunger and satiety and leads to lower energy intake during ad-libitum meals and over a full…
- Conditions
- Overweight, Obesity, Sedentary Lifestlye
- Trial name
- SWSS (NCT02012426)
- Testing
- Weight management program
- Where
- United Kingdom
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Obesity, Knee Osteoarthritis
Subcutaneous Tirzepatide Once-weekly in Patients With Obesity and Knee Osteoarthritis (STOP KNEE-OA)
This is a trial of tirzepatide in people with obesity and knee osteoarthritis. The main purpose of this study is to see if tirzepatide can reduce number of these participants who require a knee replacement.
- Conditions
- Obesity, Knee Osteoarthritis, Osteoarthritis, Knee
- Trial name
- STOP KNEE-OA (NCT06191848)
- Testing
- Tirzepatide
- Where
- 4 sites in Australia
- Volunteers
- 352 people
- Sponsor
- University of Melbourne
Obesity, Diabetes Mellitus, Type 2
Effect of BAriatric Surgery Versus Optimal Medical Therapy on Cardiovascular Health and Atherosclerosis in Obese, Type II Diabetic Patients
To assess the impact of weight loss due to bariatric surgery, as compared to the effect of optimal medical therapy alone on endothelial function, subclinical atherosclerosis, cardiovascular autonomic function in obese patient…
- Conditions
- Obesity, Diabetes Mellitus, Type 2, Atherosclerosis
- Trial name
- BASTA (NCT02331420)
- Testing
- Gastric bypass, Medical therapy
- Volunteers
- 58 people
- Sponsor
- Catholic University of the Sacred Heart
Childhood Obesity
Evaluation of an Online Lifestyle Intervention in Mexican School Children During COVID-19 Pandemic
Introduction: School closures due to the COVID-19 pandemic represent a risk factor for the development of childhood obesity due to the increase in unhealthy behaviors.
- Trial name
- NCT04772859
- Testing
- Online Lifestyle Intervention, Control Group
- Where
- Mexico
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universidad de Sonora
Healthy, Obesity
A Study to Test How Well Different Doses of BI 3034701 Are Tolerated by Japanese Healthy People and Japanese People With Obesity or Overweight
Part 1: To investigate safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of BI 3034701 in Japanese male and female participants with body mass index (BMI) ≥27.0 kg/m² or more following subcutaneous…
- Trial name
- NCT07693231
- Testing
- BI 3034701
- Where
- 3 sites in Japan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Obesity/Therapy, Obesity (Body Mass Index >30 kg/m2)
Virtual Reality Training on Balance, Postural Stability, Mobility and Quality of Life in Obese Patients
The aim of this study will be to evaluate the effect of adding Virtual reality training to balance exercise program on improving Balance, Postural Stability, mobility and Quality of life in obese patients.
- Trial name
- NCT07006870
- Testing
- Virtual Reality plus Balance Exercise Training, Balance Exercise Training
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
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