Clinical trials: Body Weight Control
Non Alcoholic Steatohepatitis
A One-Year, Randomized, Double-Blind, Placebo-Controlled Trial of Rosiglitazone in Non-Alcoholic Steatohepatitis
This study is intended to find out whether treatment with rosiglitazone improves the state of the liver and related blood markers in patients with nonalcoholic steatohepatitis (NASH).
- Trial name
- FLIRT (NCT00492700)
- Testing
- rosiglitazone
- Where
- France
- Volunteers
- 63 people
- Sponsor
- Association pour la Recherche sur les Maladies Hépatiques Virales
Obesity, Overweight
A Safety and Efficacy Study Comparing Naltrexone SR/Bupropion SR and Placebo in Obese Subjects With Type 2 Diabetes
The purpose of this study is determine whether the combination of naltrexone SR and bupropion SR is safe and effective in treating obesity in subjects with type 2 diabetes.
- Conditions
- Obesity, Overweight, Diabetes Mellitus, Type 2
- Trial name
- NCT00474630
- Testing
- Naltrexone SR 32 mg/bupropion SR 360 mg/ day, Ancillary therapy
- Where
- 53 sites in United States
- Volunteers
- 505 people
- Sponsor
- Orexigen Therapeutics, Inc
Obesity, Diet Therapy
Weight Loss on the Web: A Pilot Study Comparing a Commercial Website to a Structured Behavioral Intervention
The primary purpose of this study was to compare weight loss achieved through a behavioral online intervention vs. a commercial self-help website.
- Conditions
- Obesity, Diet Therapy, Weight Loss
- Trial name
- NCT00263172
- Testing
- behavior modification for weight loss
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Vermont
Obesity, Malignant Neoplasm
A Study to See if an iPhone Weight Management App Can Help Promote Weight Loss in Adolescents and Young Adults After a Stem Cell Transplant
This early phase I trial studies how well a behavioral weight loss intervention consisting of a smartphone application and coaching works for the promotion of weight loss in adolescents and young adults after a stem cell…
- Trial name
- NCT04453072
- Testing
- Interview, Media Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jonsson Comprehensive Cancer Center
Obesity
A Long-Term Study To Examine The Effects Of CP-945,598 On Weight Loss And Safety
The purpose of this study is to examine the long-term weight loss and safety of CP-945,598 in obese adults
- Trial name
- NCT00375401
- Testing
- CP-945,598 Treatment A, CP-945,598 Treatment B
- Where
- 82 sites in United States, Canada
- Volunteers
- 2,536 people
- Sponsor
- Pfizer
PreDiabetes, Overweight and Obesity
Zein Nanoparticles for Glycemic Control
The use of zein nanoparticles as vehicles for drug delivery is under study, but of the effects observed in empty nanoparticles, in laboratory animals, the reduction of glucose levels was something worth studying.
- Conditions
- PreDiabetes, Overweight and Obesity, Adult ALL
- Trial name
- GLUCOCAPS (NCT05560412)
- Testing
- Zein nanocapsules, control
- Where
- Spain
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Pregnancy Complications, Weight Gain
Impact of a Nutritional Intervention Program for Weight Control During Pregnancy
This is a randomized clinical trial for evaluate the impact of a nutritional intervention in the weight control of pregnant women according to the nutritional status, and consequently, the reduction of pregnancy complications.
- Trial name
- NCT00634530
- Testing
- Dietary Advice
- Where
- Brazil
- Volunteers
- 318 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Obesity & Overweight, Healthcare Worker
Personalized Nutrition Coaching for a Weight Loss Program Among Overweight and Obese Nurses
Obesity among healthcare workers has become an increasing public health concern, with potential consequences for work productivity, quality of care, and long-term health outcomes.
- Conditions
- Obesity & Overweight, Healthcare Worker, Low Physical Activity Level
- Trial name
- NCT07440979
- Testing
- Personalized Nutrition Coaching
- Where
- Indonesia
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universitas Padjadjaran
Cachexia, Non-Small Cell Lung Cancer
Safety and Efficacy of Anamorelin HCl in Patients With Non-Small Cell Lung Cancer-Cachexia (ROMANA 1)
The administration of Anamorelin in patients with Stage III-IV non-small cell lung cancer-cachexia (NSCLC-C) is expected to increase appetite, lean body mass, weight gain, and muscle strength.
- Trial name
- NCT01387269
- Testing
- Anamorelin HCl
- Where
- 60 sites in United States, Belarus and 14 more
- Volunteers
- 484 people
- Sponsor
- Helsinn Therapeutics (U.S.), Inc
Overweight, Exercise
Effects of Diet Versus Diet Plus Aerobic and Resistant Exercise Program in Overweight Women
Adult women aged 18-50 years and overweight (preobese) with a BMI of 25-30 kg/m2 will be included in the study. Participants will participate in an eight-week diet and diet plus aerobic and resistance exercise program.
- Trial name
- NCT05591794
- Testing
- Aerobic and resistance exercises, Diet program, Regular walking program
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Prematurity
PIOMI Effects on Preterm Infant Outcomes
Objective: This study aimed to investigate the effects of Premature Infant Oral Motor Intervention (PIOMI) on body weight gain, breastfeeding behavior, and length of hospital stay in preterm infants hospitalized in the neonatal…
- Trial name
- NCT07366190
- Testing
- Premature Infant Oral Motor Intervention (PIOMI), nursing care
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Obesity, Abdominal
Imaging on Core Muscles Function in Patients With Visceral Adiposity
The purpose of this study is to determine the effect of cavitation ultrasonic lipolysis, RUSI guided core muscle exercise and their combination (cavitation ultrasonic lipolysis and RUSI guided core muscles exercise) on…
- Trial name
- NCT05690659
- Testing
- device and exercise
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Deraya University
Heart Diseases, Stroke
The HARMONY Study: A Intervention to Reduce Cardiometabolic Risk in African American Women
This study will test whether a culturally-tailored nutrition and exercise intervention designed for African-American women will lead to sustained improvements in exercise and healthy eating through improvements in self-management…
- Conditions
- Heart Diseases, Stroke, Pre-diabetes, Hypertension
- Trial name
- NCT04705779
- Testing
- HARMONY, Nutrition and Exercise Education (NEEW)
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- University of North Carolina, Chapel Hill
Obesity, Extreme Obesity
Low-level Intervention for Adolescents With Extreme Obesity
While adolescents with obesity and extreme obesity are at increased risk for health complications, especially adolescents with extreme obesity rarely seek medical care, and sustained weigh loss is hardly ever achieved.
- Trial name
- STEREO (NCT01703273)
- Testing
- manual based low key group intervention (innovation), standardized, manual based routine care
- Where
- 6 sites in Germany
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Martin Wabitsch
Hemodialysis Patient
A Theory-based Fluid Self-management Program
This study aims to evaluate the efficacy of an intervention guided by the IFSMT, in which structured education and digitally delivered reinforcement strategies are designed to enhance self-management processes, including…
- Trial name
- NCT07677605
- Testing
- A Theory-based fluid self-management program
- Where
- Indonesia
- Volunteers
- 160 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
PreDiabetes, Overweight and Obesity
Effect of a Probiotic on the Glycemic Profile and the Fecal Microbiota of Prediabetic Subjects (PREDIABETCARE)
According to the data from the Di@bet.es study, which is part of the National Diabetes Strategy, the prevalence of type 2 diabetes among Spanish population is 13.8%.
- Trial name
- PREDIABETCAR (NCT04863313)
- Testing
- Probiotic
- Where
- Spain
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Obesity
Small Changes a One Year Protocol for Weight Management
A trial comparing Treatment as usual with Motivational Interviewing focussed treatment in the 'Small Changes' programme.
- Trial name
- NCT02453854
- Testing
- Group motivational interviewing
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Small Changes
Type 2 Diabetes Mellitus (T2DM)
Interventional Study of Active Weight Management in Patients With Type 2 Diabetes and Obesity in Routine Clinical Practice During 12 Months.
This study was aimed to achieve of long-term weight loss in T2DM patients by use of comprehensive lifestyle changes program, providing patients with structured diet, exercise plan, group behavioral support and group education.
- Trial name
- NCT02670928
- Testing
- Lifestyle intervention
- Where
- 2 sites in Russia
- Volunteers
- 130 people
- Sponsor
- Novartis Pharmaceuticals
Obesity
Dose-ranging Study of SKF7™ for Obesity
This study has been designed as a randomized, double blinded, multi-centric, placebo controlled, and phase II dose-ranging study.
- Trial name
- NCT04557267
- Testing
- low-dose, Middle-dose, Higher-dose
- Where
- 3 sites in Indonesia
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
PCO - Polycystic Ovaries, Obesity and Obesity-related Medical Conditions
The Effectiveness of Astaxanthin Supplementation on the Clinical Symptoms and Cardio-metabolic Profile in Women with Polycystic Ovary Syndrome
Abstract Background: This trial aims to investigate the effect of 12 weeks of 10 mg/day astaxanthin (ASX) administration compared with the control group on insulin sensitivity, lipid profile, circulating MDA levels, severity of…
- Trial name
- NCT06642363
- Testing
- Subjects in the intervention group will receive one capsule containing 10 mg Astaper day made by the "Zyest Technology Tarawat Zendig" institute in Iran. The dosage of ASX is determined based on the s
- Where
- Iran
- Volunteers
- 44 people
- Sponsor
- Isfahan University of Medical Sciences
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