Clinical trials: Body Weight Control
Obesity & Overweight
A Phase 2A Clinical Trial to Assess the Safety and Tolerability of ERX1000 in Men and Women for the Treatment of Obesity.
The primary objective is to assess the safety and tolerability of oral dose ERX1000 in obese subjects.
- Trial name
- NCT07570758
- Testing
- ERX1000
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- ERX Pharmaceuticals
Wasting, Nutrition Disorder, Child
Food Supplement Treatment for Wasting Children in Indonesia
Assessing program efficacy of under five food supplementation (PMT Biscuits) is needed after the first 6 months of exclusive breastfeeding, children were introduced to liquid and semi-solid food.
- Trial name
- NCT03509155
- Testing
- National portion & IYCF counseling, Adjusted portion & local food counseling
- Where
- Indonesia
- Volunteers
- 720 people
- Sponsor
- SEAMEO Regional Centre for Food and Nutrition
Obesity (Disorder), GLP-1 Receptor Agonist Treatment
Probiotics in Obese Patients Treated With Semaglutide
This randomized, double-blind, placebo-controlled trial evaluated the effects of a four-strain probiotic formulation in adults with obesity receiving semaglutide.
- Conditions
- Obesity (Disorder), GLP-1 Receptor Agonist Treatment, Probiotic Intervention, Diabetes Mellitus Type 2
- Trial name
- ProSem (NCT07847593)
- Testing
- Four-strain probiotic formulation
- Where
- 3 sites in Poland
- Volunteers
- 102 people
- Sponsor
- Nordic Biotic Sp. z o.o.
Obesity
Intervention Study on Weight Loss in Patients With Obesity
The goal of this clinical trial is to evaluate the feasibility of using Socratic questioning as an alternative method for weight loss in adult patients with obesity (aged 18 to 65) in a primary care setting.
- Trial name
- NCT07124832
- Testing
- Socratic Questioning Method
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Sıdıka Ece Yokuş
Gestational Diabetes, Induction of Labor Affected Fetus / Newborn
The Best Timing of Delivery in Women With GDM Study
The investigatiors aimed to conduct a well-designed RCT to firstly focus on GDM women controlled with only diet and exercise, and provide an optimize process on their timing and mode of delivery
- Trial name
- NCT03928899
- Testing
- New procedure
- Where
- China
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Asthma
Pulmonary Rehabilitation for Uncontrolled Asthma Associated With Elevated BMI
Aim to evaluate the impact of a pulmonary rehabilitation (rehab) programme tailored and delivered to overweight and obese patients with difficult asthma on: 1.
- Trial name
- PRODA01 (NCT03630432)
- Testing
- Pulmonary rehabilitation, Usual Care
- Where
- United Kingdom
- Volunteers
- 180 people
- Sponsor
- NHS Greater Glasgow and Clyde
Obesity
Probiotics in Obesity Management
Evaluate the effects of pasteurized Akkermansia muciniphila Akk11 (killed bacteria) capsules compared to placebo on body composition parameters (including weight, BMI, body fat percentage, waist - hip ratio (WHR), wrist…
- Trial name
- NCT06964932
- Testing
- Probiotc
- Where
- China
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Family Health, Child Health
Healthy Children 2021 Study in Childcare Centers
In Portugal, 17.3% of children under 10 years old are overweight and 7.7% are obese. Research has shown the implementation of healthy lifestyle promotion programs and obesity prevention, however "best practices" are far from…
- Conditions
- Family Health, Child Health, Sleep, Child
- Trial name
- HC2021 (NCT04082247)
- Testing
- The education and training of early childhood educators and their intervention on children
- Where
- Portugal
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Minho
Sarcopenic Obesity, Obesity and Obesity-related Medical Conditions
Plant vs Animal-based Protein Sources as an Anabolic and Metabolic-protective Options for SO in Older Adults
This study is testing how different types of protein - from red meat, legumes (like lentils and beans), or a mix of both - affect muscle strength, body composition, and metabolic health in older adults with obesity who are also…
- Conditions
- Sarcopenic Obesity, Obesity and Obesity-related Medical Conditions, Obesity (Body Mass Index >30 kg/m2), Sarcopenia
- Trial name
- NCT07030738
- Testing
- Legume-Based High-Protein Diet + Resistance Training, Meat-Based High-Protein Diet + Resistance Training, Mixed Legume and Meat High-Protein Diet + Resistance Training
- Where
- Israel
- Volunteers
- 180 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Obesity, Overweight
Efficacy and Safety Trial to Evaluate the Effect of SCH 497079 on Weight in Obese and Overweight Participants (Study P05483)(COMPLETED)
The purpose of this study is to evaluate the effect of SCH 497079 on weight in obese and overweight participants. The primary measure of effectiveness is the change in body weight during treatment.
- Conditions
- Obesity, Overweight, Body Weight
- Trial name
- NCT00642993
- Testing
- SCH 497079
- Volunteers
- 401 people
- Sponsor
- Merck Sharp & Dohme LLC
Overweight and Obesity
Intermittent Fasting Compared to Continuous Energy Restriction on Body Weight Loss
Obesity remains a major public health challenge. Intermittent fasting continues to gain popularity compared to continuous energy restriction as a weight-loss approach for cardiometabolic health.
- Trial name
- NCT04526847
- Testing
- Intermittent energy restriction (IER) : 5:2 diet pattern, Continuous energy restricted (CER) group
- Where
- Nepal
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Armed Police Force Hospital, Nepal
Obesity
To Investigate the Safety, Tolerability and Pharmacodynamics of GSK2890457 in Healthy Volunteers and Subjects With Type 2 Diabetes
This study is the first administration of GSK2890457 in humans. The study will be conducted in 3 parts: - Part A (conducted at a single investigative site) will determine the safety and tolerability of GSK2890457 alone in healthy…
- Trial name
- NCT01725126
- Testing
- GSK2890457, Metformin, Liraglutide
- Where
- 3 sites in United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Diabetes Mellitus, Obesity
Study of the Gut Hormone Analogue Y14 in Adult Subjects
A randomised, placebo controlled Phase I study to investigate investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of Y14 in adult subjects.
- Trial name
- NCT03673111
- Testing
- Y14
- Where
- United Kingdom
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Atrial Fibrillation, Obesity
Effect of Complex Weight-reducing Interventions on Rhythm Control in Obese Subjects With Atrial Fibrillation
Obesity is a well-established risk factor for the development of atrial fibrillation (AF), while the reduction of body weight was shown to reduce the risk of AF.
- Trial name
- HOBIT-FS (NCT04560387)
- Testing
- Physician-lead complex program of weight-reducing interventions, Bariatric surgery - sleeve gastrectomy
- Where
- Czechia
- Volunteers
- 160 people
- Sponsor
- Martin Haluzik
Child Obesity, Eating Behavior
Tween Sleep Patterns, Appetite Control, and Environment
The goal of this study is to learn about how children's sleep is related to their eating behaviors the next day, and to learn about factors that relate to eating behaviors and sleep health that are specific to preadolescent…
- Conditions
- Child Obesity, Eating Behavior, Sleep
- Trial name
- TweenSPACE (NCT05853393)
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Penn State University
Overweight Adults
Effects of a Soya-Based Fibre Beverage on Weight and Health in Overweight Adults
The goal of this intervention study is to evaluate the effect of soya-based dietary fiber beverage (SBB) in overweight adults. The main question it aims to answer is: Does the SBB effective in improving the weight and metabolic…
- Trial name
- SBB-WEIGHTLOSS (NCT07614178)
- Testing
- Soya-based dietary fibre beverage
- Where
- Malaysia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Hypertension, Overweight or Obesity
Education to Decrease in Sodium Intake Evaluated With 24 Hour Urinary Sodium Excretion (RCT)
WHO identifies as an important risk factor and potentially modifiable to high sodium intake (>2g/day 5g salt/day). Also, an insufficient consumption of potassium ( 3.5 g/day).Therefore, the results of this research could be the…
- Conditions
- Hypertension, Overweight or Obesity, Diabetes Mellitus, Type 2
- Trial name
- RCT (NCT04894344)
- Testing
- Education group
- Where
- Mexico
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Satiety, Appetite Regulation
A Placebo-Controlled Study Evaluating the Effects of Arrabina on Satiety in Healthy Adults
This study is being conducted to assess the effects of a prebiotic product, Arrabina, on appetite in healthy adults. The goal is to see if this product can help with appetite regulation, support gut health, and support weight…
- Conditions
- Satiety, Appetite Regulation, Weight Control
- Trial name
- NCT06884449
- Testing
- Arrabina Prebiotic 5.0 g, Arrabina Prebiotic 3.5 g
- Where
- 3 sites in United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Comet Bio Inc.
Obesity, Central Obesity
The Effects of Low Glycemic Index (GI) Diet on Cardiometabolic Outcomes Among Obese Chinese Adults
The aim of this study is to investigate the effects and the acceptability of low GI diet versus a conventional healthy diet on the BMI and other cardiometabolic risk factors of obese Chinese adults in Hong Kong.
- Trial name
- NCT04152213
- Testing
- Low GI diet
- Where
- Hong Kong
- Volunteers
- 166 people
- Sponsor
- Chinese University of Hong Kong
Weight Loss
Evaluation of Efficacy of a Cashew Apple Extract on Weight Management and Associated Metabolic Risk Factors in Overweight/Obese Volunteers
The purpose of this study is to assess the efficacy and safety of a cashew apple extract on weight management and associated metabolic risk factors in overweight/obese volunteers, versus placebo, after 12 weeks of treatment.
- Trial name
- NCT02493140
- Testing
- Cashew apple extract (Cashewin)
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Dialpha
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