Clinical trials: Body Weight Control
Overweight, Obesity
Use of Chewing Gum to Facilitate Appetite Control and Weight Loss
This purpose of this study was to test the use of chewing gum as an adjunct to lifestyle modification to facilitate appetite control and weight loss in overweight and obese individuals.
- Trial name
- NCT00871676
- Testing
- Lifestyle modification, Lifestyle modification plus gum
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- University of Pennsylvania
Obesity, Weight Loss
Obesity Treatment With a Very Low Energy Diet in Mexican Adults
Clinical practice guidelines recommend behavioral change protocols for obesity treatment, such as the Diabetes Prevention Program, which involves a low-energy diet, physical activity recommendations, behavioral therapy, and…
- Trial name
- NCT05631535
- Testing
- Intensive lifestyle change program with a very-low-energy diet, Intensive lifestyle change program with a low-energy diet
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Universidad de Sonora
Diabetes Mellitus, Type 2, Obesity
Endoscopic Sutured Gastroplasty with Endomina® Device Versus Standard of Care in Patients with Type 2 Diabetes and Class I Obesity: a Multi-center, Randomized Controlled Trial
The primary objective of this study is to assess the efficacy of endoscopic gastric reduction with the endomina® device, in combination with standard of care, compared to standard of care alone, on the remission of diabetes 24…
- Trial name
- ESTIME (NCT05516576)
- Testing
- endomina®
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Grenoble
Hepatic Steatosis, Overweight and Obesity
Implementation of the Fatty Liver Index in Primary Care
This trial aims to evaluate the impact on cardiovascular risk control in individuals in risk of being affected by hepatic steatosis through the implementation of a screening test (Fatty Liver Index) in Primary Care.
- Trial name
- FLI-AP (NCT06363617)
- Testing
- FLI
- Where
- Spain
- Volunteers
- 434 people
- Sponsor
- Consorci Sanitari de l'Alt Penedès i Garraf
Overweight and Obesity
Evaluation of the Plant-based Approaches to Stop Obesity Diet for the Treatment of Overweight and Obesity
The accumulation of excess of body weight is one of the most important problems worldwide, thus effective and accessible treatments are required.
- Trial name
- PASO diet (NCT03608176)
- Testing
- PASO diet group, Low-fat diet group, Waiting list group
- Where
- Mexico
- Volunteers
- 36 people
- Sponsor
- Universidad de Sonora
Overweight, Obesity
The Healthy Start Project: Primary Prevention of Overweight in Preschool Children Susceptible to Future Overweight
Obesity prevention should remain a priority, although there is some evidence of a possible leveling off in some age groups across European countries and in USA, Japan and Australia.
- Trial name
- NCT01583335
- Testing
- Lifestyle habits, including sleep and stress
- Where
- Denmark
- Volunteers
- 1,202 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Obesity
Cannabis for Obesity Trial
The goal of this study is to determine the initial efficacy of once daily oral cannabis for weight loss in obese individuals.
- Trial name
- NCT06137365
- Testing
- Cannabis
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Joshua A. Lile, Ph.D.
Obesity & Overweight, Foot and Ankle Disorders
Effects of Whole-Body Vibration With Foot Core Exercises: A Randomized Controlled Trial
This randomized, single-blind clinical trial investigates whether adding whole-body vibration (WBV) to a supervised foot core exercise program improves ankle muscle strength, balance, and proprioception in overweight and obese…
- Trial name
- FoCo-WBV (NCT07556198)
- Testing
- Supervised Foot Core Exercise Training (No Vibration), Whole-Body Vibration via DKN Technology Xg-10 Pro
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Istinye University
Hypertension, Overweight or Obesity
A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL1
GZL1 is an independent study conducted under the GZPL master protocol. GZL1 will evaluate the efficacy and safety of orforglipron for treatment of hypertension in participants with obesity or overweight.
- Trial name
- NCT06948435
- Testing
- Orforglipron
- Where
- 99 sites in United States, Argentina and 9 more
- Volunteers
- 487 people
- Sponsor
- Eli Lilly and Company
Obesity
Combined Physical-cognitive Exercise and Dietary Intervention for Postmenopausal Obese Women
This study aims to examine the effects of dietary intervention combined with physical-cognitive exergaming on cognitive performance and circulating biomarkers of obese postmenopausal women.
- Trial name
- NCT04768725
- Testing
- Dietary intervention combined with physical-cognitive exergaming, Dietary intervention, Physical-cognitive intervention
- Where
- Thailand
- Volunteers
- 92 people
- Sponsor
- Chiang Mai University
Diabetes Mellitus, Type 2 Diabetes
Improving Glycemic Control Using a Virtual Weight Control Program and Continuous Glucose Monitoring
This study is a randomized clinical trial with the primary aim examining the efficacy of a novel integrated solution of a digitally delivered behavioral weight management program tailored for diabetes utilizing a continuous…
- Conditions
- Diabetes Mellitus, Type 2 Diabetes, Obesity
- Trial name
- VITAL-CGM (NCT05935514)
- Testing
- WW Intervention, Usual Care
- Where
- 3 sites in United States
- Volunteers
- 152 people
- Sponsor
- Pennington Biomedical Research Center
Obesity, Overweight
Effect of Calcium + Vitamin D Supplementation on Weight Management in Very-low Calcium Consumers
The purpose of the study is to determine whether calcium plus vitamin D supplementation is conducive to weight and fat loss during energy restriction in very-low calcium consumers.
- Trial name
- NCT01447433
- Testing
- Calcium Carbonate, Energy restriction
- Where
- China
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Healthy Volunteers, Obesity
Phase 1 Clinical Study of MWN117 Injection in Healthy Participants and Participants With Obesity
This study is a randomized, double-blind, placebo-controlled, single-dose, dose-escalation Phase 1 clinical trial to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of MWN117 injection in healthy and…
- Trial name
- NCT07824804
- Testing
- MWN117
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Shanghai Minwei Biotechnology Co., Ltd
Weight Reduction
MyFitnessPal Pilot Study
This project is studying whether patients who use MyFitnessPal as an aid to weight loss have more success than patients who are only given traditional medical guidance from the patient's physician.
- Trial name
- NCT05059938
- Testing
- MyFitnessPal user
- Volunteers
- healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Osteo Arthritis of the Knee, Obesity & Overweight
Alignment Techniques in TKA RCT
The purpose of this research study is to compare two different methods used to align the knee during a total knee arthroplasty (TKA): technology-assisted inverse kinematic alignment, and manual-instrumented gap balancing…
- Trial name
- NCT07646158
- Testing
- Technology-assisted inverse kinematic alignment TKA, Manual-instrumented gap balancing alignment TKA
- Volunteers
- 80 people
- Sponsor
- Jacob M. Elkins
Overweight/Obesity, Prediabetes
Mobile Internet Healthcare and Three Disciplines Co-management Intervention for Overweight/Obese Prediabetic Patients
Diabetes mellitus is a chronic metabolic disease associated with a high rate of disability and mortality. Prediabetes is the intermediate stage from normal blood glucose to diabetes.
- Conditions
- Overweight/Obesity, Prediabetes, Weight Management
- Trial name
- NCT06147752
- Testing
- mobile internet healthcare and "co-management of three disciplines"
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital of Xiamen University
Overweight, Lipid Metabolism
Effects of Concurrent Training on Serum PCSK9 Levels in Adults With Overweight
Being overweight can increase the risk of heart disease. PCSK9 is a protein that helps regulate cholesterol levels in the blood. Exercise may affect PCSK9 levels, but previous studies have reported conflicting results.
- Conditions
- Overweight, Lipid Metabolism, Cholesterol Metabolism
- Trial name
- NCT07910916
- Testing
- Concurrent Aerobic and Resistance Training
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Kastamonu University
Obesity (Disorder), Bariatric Surgery
Impact of a Pro-diversity Gut Microbiota Diet After a Bariatric Surgery on Gut Microbiota, Eating Behaviour and Sensory Function
Bariatric surgery is the most effective treatment for long-term weight loss and reducing obesity-related health risks. It alters the gastrointestinal tract as well as metabolic and hormonal functions, influencing eating…
- Trial name
- BariaGut Taste (NCT07268508)
- Testing
- Nutritional counseling
- Where
- 3 sites in France
- Volunteers
- 60 people
- Sponsor
- Hospices Civils de Lyon
Obesity
PATHWEIGH: Pragmatic Weight Management in Primary Care
The study examines patient weight loss and maintenance, associated predictors (patient health characteristics and demographics), and contextual factors in the practice environment that influence the intervention's adoption…
- Trial name
- NCT04678752
- Testing
- Weight management care path, Control
- Where
- 64 sites in United States
- Volunteers
- 100,000 people
- Sponsor
- University of Colorado, Denver
Infertility, Obesity
IVF Outcome After Bariatric Surgery
This case-control study compares IVF results and live birth rates in women undergoing IVF with a history of bariatric surgery as compared to 2 age-matched control groups composed of (A) non-operated women matched on cases'…
- Trial name
- NCT02884258
- Where
- France
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Clinique Mathilde
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