Clinical trials: Body Weight Control
Diabetes Mellitus, Type 2, Obesity
Egg Consumption and Glycemic Control in Individuals With Pre- and Type II-diabetes
The intent of this study is to examine the extent to which daily incorporation of egg into a diet improves glycemic control, insulin sensitivity, lipid profiles, and body composition in overweight and obese adults with pre- and…
- Conditions
- Diabetes Mellitus, Type 2, Obesity, Pre Diabetes
- Trial name
- NCT03272074
- Testing
- Egg and egg white
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Florida State University
Obesity
Effectiveness of MD on MetS Patients
The metabolic syndrome (MetS), is a complicated condition linked to coronary artery disease.This group includes visceral obesity (abdominal or android type obesity), insulin resistance (IR), hypertension, and dyslipidaemia.The…
- Trial name
- NCT06961682
- Testing
- MD
- Volunteers
- 170 people
- Sponsor
- Assiut University
Obesity, Type 2 Diabetes Mellitus
Surgical Treatment in Diabetic Patients With Grade 1 Obesity
There will be a randomized clinical trial, non-blind, 3-arm treatment (medical, surgical, gastric bypass and ileal transposition surgery with and sleeve), which will be conducted in a single center - S.B.S.
- Trial name
- NCT01857076
- Testing
- Gastric bypass surgery, Surgical ileal transposition with sleeve, Clinical
- Where
- Brazil
- Volunteers
- 75 people
- Sponsor
- Hospital Sirio-Libanes
Obesity, Type 2 Diabetes
Pemf Therapy for the Management of Diabetes in Obese Patients
The Investigators previously developed pulsed electromagnetic field stimulation therapy (PEMF) for the metabolic activation of muscle and adipose tissues.
- Trial name
- PROMISE (NCT04183543)
- Testing
- Pulsed Electromagnetic Fields
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- National University Hospital, Singapore
Healthy, Diabetes
Meta-analysis of Oats for Diabetes Prevention and Management
Oats are a commonly consumed source of viscous soluble fibre, which has an established role in cardiovascular disease risk management including in cholesterol and glycemic control.
- Conditions
- Healthy, Diabetes, Metabolic Syndrome, Overweight and Obesity
- Trial name
- NCT04631913
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Obesity
Weight Loss In Obese Subjects Taking Either GW869682 Or Placebo 3 Times Per Day For 12 Weeks
GW869682 causes glucose to be excreted in the urine. The purpose of this study is to see whether enough calories from glucose are excreted in the urine to cause weight loss.
- Trial name
- NCT00297180
- Testing
- GW869682
- Where
- 3 sites in United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Obesity, Overweight
A Cafeteria Based Study of Weight Gain Prevention
The dramatic rise in overweight and obesity during the past several decades can be explained by environmental changes that foster increased energy intake and decreased energy expenditure.
- Trial name
- Cafeteria (NCT00573482)
- Testing
- REDE, control
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Diabetes Mellitus, Chronic Disease
Meta-analyses of Liquid Versus Solid Calories and Body Weight
Consumption of sugar-sweetened beverages (SSBs) has been linked to rising rates of overweight and obesity. The most prominent mechanism to explain the link between SSBs and obesity is that liquid calories are not perceived by the…
- Conditions
- Diabetes Mellitus, Chronic Disease, Cardiovascular Diseases, Prediabetic State
- Trial name
- NCT02702440
- Testing
- Liquid calories from sugars
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- John Sievenpiper
Pulmonary Disease, Chronic Obstructive, Obesity
INtervention Study In overweiGHT Patients With COPD
Symptoms of chronic obstructive pulmonary disease (COPD) and high body mass index (BMI) overlap. The investigators are trying to find out if a program proven to help people lose a modest amount of weight and increase their…
- Conditions
- Pulmonary Disease, Chronic Obstructive, Obesity, Weight Loss, Life Style
- Trial name
- INSIGHT COPD (NCT02634268)
- Testing
- Lifestyle Intervention
- Where
- 39 sites in United States
- Volunteers
- 684 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Central Obesity
Effectiveness of High-intensity Interval Training (HIIT) Versus Moderate-intensity Continuous Training (MICT) in Reducing Visceral Fat in Adults With Central Obesity
Obesity is a major risk factor for cardiovascular disease and diabetes as well as all-cause mortality. The prevalence of obesity has continuously increased in most countries and has doubled in over 70 countries since 1980.
- Trial name
- NCT04545320
- Testing
- Usual care control group, HIIT group, MICT group
- Where
- Hong Kong
- Sponsor
- The University of Hong Kong
Obesity
Long-term Exercise, Weight Loss and Energy Balance
In order to examine potential gender differences in the weight loss response to exercise, the investigators propose to compare equal energy expenditure of exercise for overweight men and women using levels of exercise energy…
- Trial name
- NCT01186523
- Testing
- Long Term Energy Balance
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Overweight or Obesity
Study of Olatorepatide in Adult Participants Living With Overweight or Obesity Without Diabetes
This study will test an experimental drug called olatorepatide ("study drug") to determine how safe and effective this drug is compared to placebo and how easily the body can accept this drug at different doses and dosing…
- Trial name
- NCT07685808
- Testing
- Olatorepatide
- Where
- 21 sites in United States
- Volunteers
- 360 people
- Sponsor
- Regeneron Pharmaceuticals
Healthy, Overweight and Obese Adults
A Study of SYNT-101 to Test Safety, Tolerability and Pharmacodynamics of SYNT-101 in Healthy and Overweight Adults
A Phase 1, single-center, randomized, double-blind, placebo-controlled study to evaluate the safety, tolerability, and pharmacodynamics of single and multiple dose regimens of SYNT-101 in healthy and overweight adults.
- Trial name
- NCT07307274
- Testing
- SYNT101
- Where
- Australia
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Syntis Bio
Obesity, Weight Gain
Endoscopic Argon Plasma Coagulation Vs. Control For Weight Regain After Gastric Surgery
Bariatric surgery procedures have consistently been demonstrated to reduce long-term co-morbidities and mortality. Despite its benefits, weight regain is common, usually initiating around two years after the initial procedure…
- Trial name
- NCT03055754
- Testing
- Argon randomized arm, Control arm
- Where
- Brazil
- Volunteers
- 42 people
- Sponsor
- Kaiser Clinic and Hospital
Weight Loss
Weight Management Demonstration Project: HEALTH
The study investigated the effectiveness and cost-effectiveness of a cognitive and behavioral weight management program, complemented by an interactive Web site and brief telephone coaching, implemented among TRICARE…
- Trial name
- HEALTH (NCT01307280)
- Testing
- RCT1, RCT2, RCT3
- Where
- 3 sites in United States
- Volunteers
- 2,395 people
- Sponsor
- RTI International
Obesity
First-in-man Trial of the Magnetic-controlled Balloon Inflation Mechanism of a Novel Ingestible Weightloss Microcapsule
The objective of this study is to demonstrate the ease of deployment of a novel magnetically-controlled ingestible weight loss microcapsule* and the functionality of the magnetically controlled inflation of the balloon within the…
- Trial name
- NCT03760861
- Testing
- Prototype Microcapsule Treatment
- Where
- Singapore
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Obesity
Effects of Plasmalogen on Obese Subjects
This is a 12-week, randomized, double-blind, placebo-controlled study to evaluate the effects of scallop-derived plasmalogen on brain fatigue, body weight and changes in blood plasmalogen in obese subjects aged 20-75 years old.
- Trial name
- NCT03295188
- Testing
- Plasmalogen
- Where
- Japan
- Volunteers
- 83 people
- Sponsor
- Japanese Plasmalogen Society
Obesity
Effects of the Combination of L-Arabinose and Indigestible Dextrin on Obesity
This study aims to investigate the effect of supplement containing L-arabinose and indigestible dextrin on body mass index, body fat mass, abdominal circumference, visceral fat mass, and serum biochemical parameters in overweight…
- Trial name
- NCT00880646
- Testing
- Oolong tea containing L-arabinose and indigestible dextrin
- Where
- Japan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Hiroshima University
Overweight and Obesity
A Study to Investigate the Safety and Efficacy of TE-8105 in Overweight or Obesity Participants
This is a Phase 2b, randomized, double-blind, placebo-controlled, multiple ascending dose study designed to evaluate the safety, tolerability, pharmacokinetics (PK), and efficacy of TE-8105 in adults with overweight or obesity…
- Trial name
- NCT07857473
- Testing
- TE-8105 MAD Cohort 1, TE-8105 MAD Cohort 2, TE-8105 MAD Cohort 3
- Where
- 2 sites in Australia
- Volunteers
- 204 people
- Sponsor
- Immunwork, Inc.
Obesity, Stigma, Social
Brief mHealth Self-Compassion Intervention on Internalized Weight Bias
The proposed investigation is an experimental trial among 80 adults with obesity and internalized weight bias to determine preliminary effects of a smartphone-delivered brief self-compassion mindfulness intervention on…
- Trial name
- ruby (NCT04678973)
- Testing
- Self-compassion mindfulness practice
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Duke University
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