Clinical trials: Body Weight Control
Obesity, Morbid
Randomized Controlled Trial of Fecal Microbiota Transplantation in Severe Obesity
This is a randomized, double-blinded and placebo controlled prospective trial with sixty patients to investigate the effect of fecal microbiota transplantation (FMT) on body weight in patients with severe obesity.
- Trial name
- RCTFMTOb (NCT03273855)
- Testing
- Fecal microbiota transplantation
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- University Hospital of North Norway
Obesity, Childhood, Binge Eating
Project REST: Regulation of Eating and Sleep Topography
Overweight/obesity and inadequate sleep are prevalent, and frequently co-occurring, health risks among children, both of which are associated with serious medical and psychosocial health complications including risk for…
- Conditions
- Obesity, Childhood, Binge Eating, Sleep, Self-regulation
- Trial name
- NCT04057716
- Testing
- Sleep restriction, Sleep extension
- Where
- 2 sites in United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Type 2 Diabetes Mellitus
Exercise Intensity, Glycemic Control and Abdominal Fat in People With Type 2 Diabetes: A Pilot Study
Body fat is an important risk factors for type 2 diabetes. However, not all body fat is the same. Research suggests that fat stored in the abdomen is most harmful. This is known as intra-abdominal fat.
- Trial name
- NCT01144078
- Testing
- Traditional Intensity Exercise, High Intensity Interval Exercise
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of Alberta
Otherwise Healthy Overweight or Obese
A Study of Safety, Tolerability, and Pharmacokinetics of Multiple-Ascending Doses of PHP-303 in Otherwise Healthy Overweight or Obese Subjects
This is a Phase 1, randomized, double-blind, placebo-controlled multiple-ascending dose (MAD) study designed to evaluate the safety, tolerability, and pharmacokinetics (PK) of PHP-303 in otherwise healthy overweight or obese…
- Trial name
- NCT03775278
- Testing
- PHP-303
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- pH Pharma
Smoking, Body Weight
Treating Adults at Risk for Weight Gain With Interactive Technology
Obesity represents a chronic disease associated with significant cardiovascular disease (CVD) morbidity and mortality. Weight gain in young adults adversely impacts the development of CVD risk factors.
- Trial name
- TARGIT (NCT01199185)
- Testing
- Smoking Cessation, Smoking Cessation plus Weight Loss
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
PreDiabetes, Obesity
Effect of Mango Consumption on Individuals with Pre-diabetes
This study is designed to explore the effect of mango consumption on glycemic indices, cardiovascular health, and body composition in overweight and obese individuals with prediabetes.
- Trial name
- NCT05571800
- Testing
- Mango
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Florida State University
Mental Illness, Obesity
Using MOVE! With Seriously Mentally Ill Veterans
This study involves a controlled trial of an optimized version of a weight management and physical activity psycho-educational intervention (called MOVE!) with 200 obese and overweight veterans with serious mental illness.
- Trial name
- NCT00323193
- Testing
- MOVE!
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Obesity & Overweight, Weight Management
Family-Based Weight Wellness Treatment Through Food is Medicine and Group Medical Visits in Pediatric and Adult Primary Care
The proposed project aims to implement and evaluate a novel, family-based lifestyle medicine intervention integrating group Shared Medical Appointments (SMAs) for parents and adolescents with a twelve-month medically tailored…
- Trial name
- NCT07717658
- Testing
- Culinary medicine classes, Medically Tailored Groceries, Shared Medical Appointments
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Tufts University
Childhood Obesity
Wellness Action Plan Trial Addressing Childhood Obesity
The objective of this study was to determine the effectiveness of a novel Wellness Action Plan aimed at 1) improving parent recall of diet and activity plans 2) increasing follow-through with plans and 3) aiding parents in…
- Trial name
- NCT02185248
- Testing
- Wellness Action Plan
- Where
- United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Roohi Kharofa, MD, MPH
Metabolic Syndrome
ENDOBARRIER® and Conventional Therapy in the Management of Metabolic Syndrome in Obese Patients
Obesity and metabolic syndrome (MS) are closely interrelated leading to increased mortality, mainly due to cardiovascular disease. In addition, some cancers are much higher when obesity is associated with metabolic syndrome.
- Trial name
- ENDOMETAB (NCT02297555)
- Testing
- ENDOBARRIER®
- Where
- 10 sites in France
- Volunteers
- 82 people
- Sponsor
- University Hospital, Lille
Metabolic Syndrome X, Diabetes Mellitus, Type 2
Efficacy of Topiramate for Weight Loss in Subjects With Metabolic Syndrome
The purpose of this study is to evaluate the efficacy of topiramate compared to placebo in the treatment of obesity in metabolic syndrome.
- Trial name
- NCT00243984
- Testing
- topiramate
- Where
- 5 sites in United States
- Volunteers
- 90 people
- Sponsor
- Northeastern Ohio Universities College of Medicine
Gastrointestinal, Overweight , Obesity
A Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Impact of CLB101TM️ on Gut Health in Healthy, Overweight Individuals
Anaerostipes caccae CLB101TM️ is a next-generation probiotic isolated from healthy humans. It was shown to be in decreased abundance in people with protein-based food sensitivities/allergies.
- Trial name
- NCT07336615
- Testing
- CLB101™️
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- ClostraBio Inc.
Obesity
Efficacy and Safety of THR-4109 in Obese Subjects
The purpose of this study is to evaluate the safety and effect of THR-4109 on weight loss in obese subjects over a 24-week treatment period.
- Trial name
- NCT00485017
- Testing
- THR-4109
- Where
- 20 sites in Russia, Sweden
- Volunteers
- 220 people
- Sponsor
- Theracos
Evaluate the Safety and Tolerability, Healthy and Overweight or Obese Participants
Phase 1 Study of Ascending Doses of CMS-D008 in Healthy and Overweight/Obese Adults
This study is a first-in-human clinical trial of CMS-D008 conducted in Chinese healthy and overweight or obese adult participants, consisting of three parts: Part-1 Single Ascending Dose (SAD) study (hereinafter referred to as…
- Trial name
- NCT07518589
- Testing
- CMS-D008
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Shenzhen Kangzhe Biotechnology Co., Ltd.
Obesity
Healthy Weight Management Project for Overweight and Obesity Children
Childhood obesity is a significant public health concern worldwide. In China, childhood obesity has dramatically increased as the economy has grown quickly over the past decades.
- Trial name
- NCT05482191
- Testing
- Lifestyle intervention
- Where
- China
- Volunteers
- 331 people, healthy volunteers welcome
- Sponsor
- Ningbo No. 1 Hospital
Adults With Overweight/Obesity and Type 2 Diabetes
A Study to Assess the Efficacy, Safety and Tolerability of AT673 Co-administered With Semaglutide in Adult Participants With Type 2 Diabetes (T2D) and Overweight or Obesity
The goal of this clinical trial is to learn if AT673 contributes to additional weight loss and glycemic control when given with semaglutide in participants with overweight/obesity and type 2 diabetes.
- Trial name
- NCT07724340
- Testing
- AT673 low dose, AT673 high dose
- Where
- 8 sites in United States
- Volunteers
- 150 people
- Sponsor
- Antag Therapeutics
Obesity, Childhood, Pediatric Obesity
Treatment Efforts Addressing Child Weight Management by Unifying Patients, Parents & Providers
The US Preventive Services Task Force (USPSTF) recommends that providers screen children aged 6 years and older for obesity and offer or refer them to a comprehensive behavioral intervention (≥26 hours over a period of up to 12…
- Conditions
- Obesity, Childhood, Pediatric Obesity, Childhood Obesity, Adolescent Obesity
- Trial name
- TEAM UP (NCT03843424)
- Testing
- eSOC program, FBT program
- Where
- 7 sites in United States
- Volunteers
- 1,460 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Obesity, Overweight
A Study of TG103 Injection in the Management of Non-diabetic Overweight or Obesity
This study is a randomized, double-blind, placebo-controlled, parallel phase 2 study to evaluate efficacy, safety, pharmacokinetic characteristics and immunogenicity of TG103 injection for weight management in non-diabetic…
- Trial name
- NCT06226090
- Testing
- TG103 7.5 mg, TG103 15 mg, TG103 22.5 mg
- Where
- China
- Volunteers
- 314 people
- Sponsor
- CSPC Baike (Shandong) Biopharmaceutical Co., Ltd.
Cannabis Use, Cachexia; Cancer
Safety and Efficacy of Inhaled Synthetic THC/CBD for Improving Physical Functioning and for Modulating Cachexia Progression in Patients With Advanced Cancer and Associated Cachexia
A large number of patients with advanced cancer also suffer from cachexia. Cachexia is a syndrome characterized by loss of skeletal muscle mass (with/or without loss of fat mass) that cannot be reversed by nutritional support and…
- Conditions
- Cannabis Use, Cachexia; Cancer, Advanced Cancer
- Trial name
- SERENITY (NCT04001010)
- Testing
- PPP011
- Where
- Canada
- Volunteers
- 334 people
- Sponsor
- Tetra Bio-Pharma
Hypothalamic Obesity
A Study of Octreotide Depot vs Saline Control in Pediatric Hypothalamic Obesity Patients
The extension protocol is designed to allow those patients randomized to placebo in the core portion of the protocol to receive a 6 month treatment of open label octreotide and allow those patients randomized to octreotide who…
- Trial name
- NCT00171613
- Testing
- Octreotide
- Volunteers
- 32 people
- Sponsor
- Novartis
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