Clinical trials: Body Weight Control
Cachexia, Chronic Obstructive Pulmonary Disease
Safety, Tolerance and Efficacy of an Oral Nutritional Supplement in Chronic Heart Failure and Chronic Obstructive Pulmonary Disease Patients
To test the compliance, tolerance, safety and to get preliminary insights into the efficacy of a new oral nutritional supplement (containing n-3 fatty acids, amino acids and antioxidants) designed to prevent or delay cachexia and…
- Conditions
- Cachexia, Chronic Obstructive Pulmonary Disease, Chronic Heart Failure
- Trial name
- NCT00852020
- Testing
- oral nutrition supplement, food for special medical purposes
- Where
- 4 sites in Germany, Poland
- Volunteers
- 60 people
- Sponsor
- Fresenius Kabi
Overweight or Obesity
A Study of ZT002 Injection in Participants With Overweight or Obesity
This study will comprise a randomized, double-blind, placebo-controlled, multiple-ascending-dose, safety, tolerability, and pharmacokinetics study of ZT002 in participants with Overweight or Obesity.
- Trial name
- NCT06371326
- Testing
- ZT002 Injection
- Where
- China
- Volunteers
- 28 people
- Sponsor
- Beijing QL Biopharmaceutical Co.,Ltd
Visceral Fat
The Healthy Diet and Lifestyle Study
This pilot study aims to develop a study design to test the difference between a fasting diet and a heart healthy diet, assess participants' adherence to the study design, and to test whether either diet helps to reduce fat…
- Trial name
- HDL (NCT03639350)
- Testing
- IER+MED group, DASH group
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
Weight Loss, Obesity
A Trial to Test an Acceptance-based Therapy Program Among Adolescent Girls With Overweight/Obesity
The purpose of this study is to investigate the effects of an acceptance-based therapy weight loss intervention compared with enhanced care for adolescents.
- Conditions
- Weight Loss, Obesity, Overweight
- Trial name
- NCT04484831
- Testing
- ABT Weight Loss Intervention, Enhanced Care
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Florida
Obesity
Effects of Exercise on Arterial Function and Insulin Resistance Syndrome in Pre-pubertal Obese Children
The main purpose of this project is to investigate the effects of an exercise program on arterial function and cardiovascular diseases risk factors in obese and lean pre-pubertal children.
- Trial name
- NCT00801645
- Testing
- Exercise
- Where
- Switzerland
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Obesity, Childhood
A Mobile Phone App to Promote Healthy Diet and Physical Activity in 2.5-year-olds
Childhood obesity is still a major global health issue. The preschool age (2-5 years) has been identified as a critical period to intervene, Mobile technology (mHealth) has been successful for weight loss and behavior changes in…
- Trial name
- NCT04147039
- Testing
- MINISTOP 2.0
- Where
- 2 sites in Sweden
- Volunteers
- 552 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Obesity With Diabetes, Overweight With Diabetes
Efficacy and Safety of Ribupatide Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes
The primary objective of this study is to demonstrate that ribupatide (KAI-9531) subcutaneous (SC) injection once weekly is superior to placebo on: Percent change in body weight Change in hemoglobin A1c (HbA1c)
- Trial name
- KaiNETIC-2 (NCT07284901)
- Testing
- Ribupatide
- Where
- 173 sites in United States, Argentina and 9 more
- Volunteers
- 1,270 people
- Sponsor
- Kailera
Obesity, Morbid, Pregnancy
3D Ultrasound-guided Labor Epidural Analgesia in the Morbid Obese Parturient
This study will be a randomized control study, with the objective to evaluate epidural analgesia success rates between the two methods (Blind Approach versus Accuro Device).
- Conditions
- Obesity, Morbid, Pregnancy, Pain
- Trial name
- NCT03405311
- Testing
- Rivanna Accuro 3D Ultrasound Device, Palpation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Osteoarthritis, Overweight and Obesity
Effects of an Online Training Program for Physiotherapists About Weight Management for People With Osteoarthritis
A randomized controlled trial for which the primary objective is to evaluate the effects of an online training program on physiotherapist's self-reported confidence in knowledge about weight management for people with…
- Trial name
- NCT04574804
- Testing
- Online training program in weight management for osteoarthritis
- Where
- Australia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Melbourne
Breast Neoplasm Female
Effect of Mindful Eating on Weight Management in Breast Cancer Survivors
This pilot study examined changes in anthropometric measures as a result of and feasibility/ acceptability of a mindful eating intervention for overweight and obese postmenopausal breast cancer survivors.
- Trial name
- NCT03972540
- Testing
- Mindful eating intervention
- Volunteers
- 13 people
- Sponsor
- University of Georgia
Childhood Obesity
Genetic Predisposition to Food Cue Reactivity in Children
This study assesses the associations between genetic factors, food-cue-related neural reactivity, self-regulatory capacity, eating in the absence of hunger (EAH), and adiposity gain in children.
- Trial name
- NCT03766191
- Testing
- Food Ads, Non-food Ads
- Where
- United States
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- Trustees of Dartmouth College
Liver Cirrhoses, Portal Hypertension Related to Cirrhosis
Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease
Cirrhosis is a form of advanced liver disease that can lead to serious complications, especially when combined with severe obesity.
- Conditions
- Liver Cirrhoses, Portal Hypertension Related to Cirrhosis, Severe Obesity, TIPS
- Trial name
- OPTIMAL (NCT07058155)
- Testing
- Transjugular Intrahepatic Portosystemic Shunt (TIPS), Sleeve Gastrectomy, Anti-Obesity Pharmacotherapy (Class Effect)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- The Cleveland Clinic
Obesity, Overweight
A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight for the Maintenance of Weight Loss
This was a study of tirzepatide in participants with obesity or overweight. The main purpose was to learn more about how tirzepatide maintained body weight loss.
- Trial name
- SURMOUNT-4 (NCT04660643)
- Testing
- Tirzepatide
- Where
- 70 sites in United States, Argentina and 3 more
- Volunteers
- 783 people
- Sponsor
- Eli Lilly and Company
Spinal Cord Injury, Obesity
Telenutrition in Spinal Cord Injury
The purpose of the study is to provide tele-nutrition counseling after a spinal cord injury (SCI). During the three months of participation, subjects will be given an iPad and the iPad will be used to record meals using a photo…
- Trial name
- NCT03714217
- Testing
- Telenutrition Counseling
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Santa Clara Valley Health & Hospital System
Weight Management, Treatment Of Obesity
A Trial In Diabetic Patients To Assess Effect Of CE-326,597 On Glucose Control And Body Weight
Study of whether the investigational drug CE-326,597 improves glucose control and results in body weight loss in patients with type 2 diabetes
- Trial name
- NCT00542009
- Testing
- CE-326,597 100 mg QD, CE-326,597 50 mg QD, CE-326,597 25 mg QD
- Where
- 54 sites in United States, Bulgaria and 5 more
- Volunteers
- 252 people
- Sponsor
- Pfizer
Obesity
Randomized, Controlled, Open, Comparative Intervention Study for Obesity Prevention in Children
Randomized, controlled, open, comparative intervention study in 270 children at risk for obesity.Patients will be randomly allocated into one of two behavior intervention groups or control group in ratio of 1:1:1.The study will…
- Trial name
- 4055obesityprv (NCT00438555)
- Testing
- Parents and children group, Parent's group
- Where
- Israel
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Type 2 Diabetes Mellitus, Obesity
The TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes
This research study is being performed to begin to determine the effectiveness of two dominant bariatric surgery procedures versus an intensive lifestyle intervention to induce weight loss in patients and promote improvements in…
- Trial name
- TRIABETES (NCT01047735)
- Testing
- Roux-en-Y Gastric Bypass Surgery, Laparoscopic Adjustable Gastric Banding, Lifestyle Weight Loss Intervention
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- University of Pittsburgh
Obesity, Binge-Eating Disorder
A Study of the Effectiveness and Safety of Topiramate in the Treatment of Moderate to Severe Binge-eating Disorder Associated With Obesity
The purpose of this study is to evaluate the safety and effectiveness of topiramate compared to placebo in reducing the number of binge days in patients with moderate to severe binge-eating disorder associated with obesity.
- Trial name
- NCT00210808
- Testing
- topiramate
- Volunteers
- 407 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Overweight, Obesity
A Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body Weight
The purpose of this clinical study is to look at how well a study medicine called cagrilintide helps people living with excess body weight to lose weight.
- Trial name
- RENEW 4 (NCT07745504)
- Testing
- Cagrilintide
- Where
- 36 sites in United States, Greece and 4 more
- Volunteers
- 285 people
- Sponsor
- Novo Nordisk A/S
Non-alcoholic Steatohepatitis (NASH)
A Study to Assess Safety, Tolerability, PK and PD of AZD2693 in Non-alcoholic Steatohepatitis Patients
This study is intended to investigate the safety and tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of AZD2693, following subcutaneous (SC) administration of multiple ascending doses in participants with…
- Trial name
- NCT04483947
- Testing
- AZD2693
- Where
- 16 sites in United States
- Volunteers
- 74 people
- Sponsor
- AstraZeneca
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