Clinical trials: Body Weight Control
Obesity, Overweight
A Study of Orforglipron for the Maintenance of Body Weight Reduction in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities (ATTAIN-MAINTAIN)
The main purpose of this study is to evaluate the efficacy and safety of orforglipron on maintenance of body weight reduction in participants who previously completed treatment with injectable tirzepatide (Zepbound) or injectable…
- Trial name
- NCT06584916
- Testing
- Orforglipron
- Where
- 29 sites in United States, Puerto Rico
- Volunteers
- 376 people
- Sponsor
- Eli Lilly and Company
Obesity
Study of VI-0521 Compared to Placebo in Treatment of Obesity in Adults
The purpose of this study is to evaluate the efficacy and safety of two doses of VI-0521 compared to placebo in treatment of obesity in an adult population with BMI ≥ 35.
- Trial name
- NCT00554216
- Testing
- VI-0521
- Where
- 5 sites in United States
- Volunteers
- 1,267 people
- Sponsor
- VIVUS LLC
Overweight/Obesity
A Clinical Trial of TQF3250 Capsules in Overweight/Obese Trial Participants With Poor Weight Control Through Simple Lifestyle Intervention
This is a multicenter, randomized, double-blind, placebo-controlled Phase 1b clinical study. All trial participants are required to use TQF3250 capsules or placebo.
- Trial name
- NCT07798284
- Testing
- TQF3250 capsules
- Where
- 10 sites in China
- Volunteers
- 80 people
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Type 2 Diabetes Mellitus
Addition of Liraglutide to Patients With Type 2 Diabetes Treated With Multiple Daily Insulin Injections
Liraglutide, a GLP-1-analogue has been shown to be an effective treatment option in patients on oral anti-diabetes therapy with beneficial effects on both glycaemic control and weight.
- Trial name
- NCT02113332
- Testing
- Liraglutide
- Where
- 14 sites in Sweden
- Volunteers
- 124 people
- Sponsor
- Vastra Gotaland Region
Diabetes Mellitus, Type 2, Overweight or Obesity
T2DM Intensity Lifestyle Intervention
This RCT study will evaluate the effect of a lifestyle intervention on overweight or obese patients with type 2 diabetes mellitus.
- Trial name
- NCT05561855
- Testing
- lifestyle intervention
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Ningbo No. 1 Hospital
Dietary Restraint
The Effects of Weight and Nutrition Education on Weight Control Beliefs, Body Image, Self-Esteem and Eating Patterns in Undergraduate Dieters
People who diet typically believe they can control their weight. People who believe they should control their weight are more likely to have poor body image, low self-esteem and disordered eating.
- Trial name
- NCT07349316
- Testing
- Weight Science Education, Nutrition Education, Sleep Education
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Obesity, Type 2 Diabetes Mellitus
The Heat Study: 2 Year Lifestyle Intervention in Overweight Women to Encourage Weight Management
The purpose of this trial is to determine the most cost effective programme for overweight and obese individuals to maintain weight loss over a 2 year period.
- Trial name
- NCT00128336
- Testing
- Lifestyle: diet and exercise intervention
- Where
- New Zealand
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Otago
Overweight and Obesity, Healthy
The Effects of Intake of Protein From Cod Fillet and Cod Residual Material on Lipid Regulation, Glucose Regulation and Inflammation in Overweight or Obese Adults.
A high intake of fish is associated with positive health effects, including prevention and treatment of chronic non-communicable diseases, such as cardiovascular diseases (CVDs) and type 2 diabetes.
- Trial name
- COD2017 (NCT03538821)
- Testing
- Intact cod protein from fillet, Intact cod protein from residual material, Control
- Where
- Norway
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Post Partum, Breast Feeding
The Effect of WhatsApp-Based Education and Counseling on Breastfeeding Self-Efficacy, Body Satisfaction, Healthy Lifestyle Behaviors, and Weight Retention in Postpartum Women: A Randomized Controlled Trial
Brief Summary: This randomized controlled trial aimed to evaluate the effect of WhatsApp-based education and counseling on breastfeeding self-efficacy, body satisfaction, healthy lifestyle behaviors, and weight retention in…
- Conditions
- Post Partum, Breast Feeding, Body Image, Health Behavior
- Trial name
- NCT07185906
- Testing
- education
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Inonu University
Metabolic Associated-dysfunction Steatotic Liver Disease (MASLD), Metabolic Associated-dysfunction Steatohepatitis (MASH)
Behavioral Lifestyle Intervention for Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) in Adults
The goal of this randomized control trial study is to compare an acceptance-based weight loss program with an occupational therapy behavioral lifestyle modification intervention in adults with metabolic associated-dysfunction…
- Trial name
- NCT06121999
- Testing
- Standard of care acceptance-based behavioral weight loss program, Occupational therapy dietary and lifestyle modifications
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Grand Valley State University
Apnea, Sleep Disorders
A Study to Learn About the Monthly Dosing Study Medicine Called Berobenatide in Adults With Breathing Problems During Sleep and Overweight or Obesity Who Use a Breathing Machine (PAP) (VESPER-OSA 1)
This study is being done to learn about the safety and effects of a study medicine called berobenatide (bear-oh-BEN-uh-tide). The study will see if berobenatide can help adults with breathing problems during sleep (obstructive…
- Conditions
- Apnea, Sleep Disorders, Overweight and/or Obesity
- Trial name
- NCT07823608
- Testing
- Berobenatide
- Where
- 6 sites in United States
- Volunteers
- 258 people
- Sponsor
- Pfizer
Muscle Wasting, Obesity & Overweight
Testing the Efficacy, Safety, and PK of 20E in Patients With Obesity Who Are Starting Treatment With the GLP-1 Agonist Semaglutide for Weight Loss.
The goal of this clinical trial is to learn if BIO101 treatment can improve the muscle strength of participants males and females, aged 18 to 84 years old, suffering from obesity (BMI≥30) or overweight (BMI ≥ 27) with one or more…
- Conditions
- Muscle Wasting, Obesity & Overweight, Obesity
- Trial name
- OBA (NCT07411378)
- Testing
- BIO101, Semaglutide
- Volunteers
- 164 people
- Sponsor
- Biophytis
Overweight
Evaluate the Efficacy and Safety of LMT1-48 on Reducing Body Fat in Overweight Subject
The purpose of this study is to evaluate the safety and efficacy of LMT1-48(Probiotics) compared to a placebo in reducing the body fat in overweight subjects
- Trial name
- NCT03759743
- Testing
- LMT1-48
- Where
- South Korea
- Volunteers
- 97 people
- Sponsor
- Medy-Tox
Weight, Appetite
A Trial Comparing a Diet Including Products Aimed at Targeting Satiety
This multi-centre, randomised controlled trial will be conducted over 12-weeks to evaluate whether lower appetite is associated with weight loss maintenance success.
- Trial name
- SATIN (NCT02485743)
- Testing
- Active Diet Products
- Where
- United Kingdom
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- Professor Jason Halford
Obesity and Obesity-related Medical Conditions
Empowering Healthy Lifestyle Behaviour Through Personalised Intervention Portfolios to Prevent and Control Obesity in Children - UEV Pilot Study
This study is being performed under the European Consortium HealthyW8 that has the main objective of developing a digital tool for personalized recommendations for healthy lifestyle and prevention of obesity.
- Trial name
- UEVCh_HW8 (NCT06933121)
- Testing
- Digital twin for personalized recommendations
- Volunteers
- 40 people
- Sponsor
- University of Évora
Obesity, Dietary Modification
Drinking Water to Reach or Maintain a Healthier Weight
The purpose of this study is to find out if drinking extra water helps people lose or maintain weight loss and reduce hunger and, if so, what volume of water is most effective and when is it best to drink it.
- Trial name
- NCT02331316
- Testing
- Daily extra water intake
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- ThinkWell
Pregnancy Related, Obesity
Misoprostol Dosing in BMI Greater Than 30
The investigators are performing a randomized controlled-trial investigating if 50mcg (compared to 25 mcg) of vaginal misoprostol reduces the time from induction start to delivery in obese women.
- Conditions
- Pregnancy Related, Obesity, Labor Onset and Length Abnormalities
- Trial name
- MD30 RCT (NCT05262738)
- Testing
- 50 Micrograms Vaginal Misoprostol (Intervention), 25 Micrograms Vaginal Misoprostol (Control)
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Texas at Austin
Hormone, Cardiovascular
Cardiometabolic and Hormonal Adaptations to 4-Month Zumba Training in Overweight/Obese Women
This study aims to evaluate the effects of a 4 month Zumba training program on cardiometabolic, hormonal, inflammatory, hepatic, renal, and functional parameters in overweight and obese women.
- Conditions
- Hormone, Cardiovascular, Obesity & Overweight
- Trial name
- NCT07264348
- Testing
- Zumba training
- Volunteers
- 73 people
- Sponsor
- High Institute of Sports and Physical Education of Kef
Obesity
High Density Lipoprotein Turnover
The objective of the study is to evaluate the effect of Rimonabant 20mg in comparison to placebo, on HDL and VLDL lipoprotein kinetics, over a 12 months period.
- Trial name
- NCT00408148
- Testing
- Rimonabant
- Where
- 4 sites in Australia, Finland and 2 more
- Volunteers
- 64 people
- Sponsor
- Sanofi
Metabolic Syndrome, Obesity and Obesity-related Medical Conditions
Effects of Intermittent Fasting and Exercise on Inflammation, Metabolism, and the Microbiome in Metabolic Syndrome
The goal of this intervention trial is to assess the effects of intermittent fasting, both alone and in combination with high-intensity interval training, on patients with obesity and metabolic syndrome.
- Trial name
- FIT (NCT06885255)
- Testing
- Alternate day fasting, Time restricted eating, High-intensity interval training
- Where
- Germany
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
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