Clinical trials: Body Weight Control
Obesity, Sarcopenia
Effectiveness of Combined GLP-1/GIP Dual Agonist Therapy and Structured Exercise on Skeletal Muscle Morphology, Quality, and Physical Function in Overweight and Obese Individuals
This randomized controlled trial aims to investigate the effects of a 24-week home-based progressive resistance exercise program combined with tirzepatide treatment on skeletal muscle mass, muscle quality, and functional capacity…
- Conditions
- Obesity, Sarcopenia, Overweight (Without Type 2 Diabetes) With Weight-related Comorbidities
- Trial name
- NCT07609160
- Testing
- Resistance exercise, Lifestyle recommendations
- Volunteers
- 108 people
- Sponsor
- Acibadem University
Obesity
Fruit and Vegetable Juice Concentrate Effects on RBP4 and Antioxidant Capacity in Lean and Overweight 6-10 Year Old Boys
Our study aims to evaluate if the consumption of a Fruit and Vegetable Juice Concentrate (FVJC) vs. placebo can exert changes in the serum levels of Retinol Binding Protein 4 (RBP4), carotenoids, tocopherol, antioxidant capacity…
- Trial name
- FVJC (NCT00842543)
- Testing
- Fruit and Vegetable Juice Concentrate (FVJC)
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Asthma, Obesity
Effectiveness and Efficiency of Mobile Technology in Disease Control of Asthmatic Obese Patients
Single-center open-label randomized pilot study to assess the effectiveness and efficiency of a mobile technology based intervention for asthma and obesity control.
- Trial name
- ASMATIC (NCT03964740)
- Testing
- Mobile App intervention
- Where
- Spain
- Volunteers
- 33 people
- Sponsor
- Hospital Universitario Virgen Macarena
Contrast Media Dosing
Dosing Iodinated Contrast Media According to Lean vs. Total Body Weight
The purpose of this study is to evaluate the effect of dosing iodinated contrast media according to a patient's total body weight vs. lean body weight.
- Trial name
- NCT03415997
- Testing
- Iohexol
- Where
- Canada
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Obesity
Phase 1 Study of NGM313 in Healthy Adult Participants
The purpose of this study is to determine the safety and tolerability of NGM313, both single dose and multiple doses, in normal healthy overweight and obese adult participants.
- Trial name
- NCT02708576
- Testing
- NGM313
- Where
- Australia
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- NGM Biopharmaceuticals, Inc
Healthy Volunteers, Body Weight
Weight Management Interactions in a Virtual Clinical Environment
This study is part of an effort to learn about interactions between doctors and patients. We aim to understand how women feel about techniques that doctors use to talk with patients about their weight.
- Trial name
- NCT01443910
- Where
- United States
- Volunteers
- 318 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Cervical Pain
Comparison of Weight Bearing Thrust Manipulation With Non Weightbearing Thrust Manipulation in Patients With Forward Head Posture
This randomized controlled trial was performed in MMRC (Majestic medicine rehabilitation Sciences) Islamabad in February 2023 and consisted of patients having neck pain and forward head posture.
- Trial name
- NCT05762289
- Testing
- Thrust Manipulation (in weight bearing and non weight bearing)
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Yusra Medical and Dental College
Obesity, Sarcopenia
The Effect of the DASH Diet Containing Meat on Muscle and Metabolic Health in Older Adults
Age-related changes in body composition, muscular fitness, and metabolic health resulting in the onset of obesity, sarcopenia, and chronic diseases are profound public health issues that are in need of immediate attention.
- Conditions
- Obesity, Sarcopenia, Aging
- Trial name
- NCT04127240
- Testing
- DASH diet containing daily intakes of red meat
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- South Dakota State University
Morbid Obesity, Noninvasive Ventilation
Use of High Flow Nasal Cannula During Sedation of Morbidly Obese Patients in the Endoscopy Suite
This study evaluates the ability of high flow nasal cannula versus nasal cannula to oxygenate morbidly obese patients undergoing moderate to deep sedation for gastrointestinal procedures.
- Conditions
- Morbid Obesity, Noninvasive Ventilation, Deep Sedation
- Trial name
- NCT02859597
- Testing
- High flow nasal cannula, Nasal Cannula
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Pregnancy Related, Weight Gain
HealthyPregnancy - Digital Support for Pregnant Women with a BMI At 25 or Above (BMI≥25)
The study aims to examine the effectiveness of a digital care guide offering support and information on diet, physical exercise and mental well-being on pregnancy weight gain among pregnant women with a BMI at 25 or above in a…
- Trial name
- NCT06734910
- Testing
- HealthyPregnancy
- Where
- 2 sites in Denmark
- Volunteers
- 450 people
- Sponsor
- Center for Clinical Research and Prevention
Prader-Willi Syndrome, Aggression
Guanfacine Extended Release for the Reduction of Aggression and Self-injurious Behavior Associated With Prader-Willi Syndrome
This is a placebo-controlled clinical trial to assess whether Guanfacine Extended Release (GXR) reduces aggression and self injurious behavior in individuals with Prader Willi Syndrome (PWS).
- Conditions
- Prader-Willi Syndrome, Aggression, Self-Injurious Behavior, Pathologic Processes
- Trial name
- PWS-GXR (NCT05657860)
- Testing
- Guanfacine Extended Release
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Maimonides Medical Center
Obesity, Overweight
A Randomized Controlled Trial Comparing the Effectiveness of Different Treatment Options for Weight Management After Discontinuation of Semaglutide and Tirzepatide (GLP1 Transition Trial)
The study compares the effectiveness of treatment options for weight management after discontinuing semaglutide and tirzepatide. The primary outcome is absolute and percentage weight change at 12-weeks.
- Trial name
- NCT06605703
- Testing
- WW Clinic, Bupropion-Naltrexone, Bupropion-Naltrexone-Metformin
- Where
- United States
- Volunteers
- 226 people
- Sponsor
- WW International Inc
Obesity & Overweight, Metabolic Disorders
Diet and WB-EMS Effects in Obesity
Obesity is a major global health problem associated with metabolic dysfunction, altered adipokine signaling, and impaired appetite regulation.
- Conditions
- Obesity & Overweight, Metabolic Disorders, Electrotherapy
- Trial name
- DEMO-OB (NCT07562724)
- Testing
- Energy-Restricted Diet, Whole-Body Electromyostimulation (WB-EMS)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Firat University
Obesity, Risk Factors
Motivational Interviewing to Promote Healthy Behaviours in Young Adults
The overall goals of this project are to evaluate the feasibility of web-based nurse-led motivational interviewing and educational interventions to promote healthy behaviours for obesity prevention and maintenance of healthy…
- Trial name
- Motivate (NCT05264740)
- Testing
- Motivational interviewing, Educational materials
- Where
- Canada
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- McMaster University
PreDiabetes, Obesity
Effect of Nutritional Supplements on Clinical Outcomes in Patients With Prediabetes and Obesity
This study aims to improve blood glucose and weight in patients with prediabetes and obesity through health education, nutritional supplement interventions, clinical evaluation, and close clinical follow-up.100 patients with…
- Trial name
- NCT05273840
- Testing
- Ivital Control, lifestyle intervention
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Ningbo No. 1 Hospital
Obesity, Overweight
Improving Glycemic Control With Electrical Stimulation
Once written consent is obtained, the participant will be provided with an accelerometer to be worn for 7 days to assess current physical activity levels.
- Conditions
- Obesity, Overweight, Insulin Resistance
- Trial name
- NCT03947697
- Testing
- Neuromuscular Electrical Stimulation (Sensory), Neuromuscular Electrical Stimulation, Resistance Training
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas, El Paso
Attention-Deficit / Hyperactivity Disorder, Depression
Prevention of Comorbid Depression and Obesity in Attention-deficit/ Hyperactivity Disorder
Depression and obesity are very common among adolescents and young adults with attention-deficit/ hyperactivity disorder (ADHD). However, intervention programmes to prevent these comorbid disorders rarely exist.
- Conditions
- Attention-Deficit / Hyperactivity Disorder, Depression, Obesity
- Trial name
- PROUD (NCT03371810)
- Testing
- Bright light therapy, Physical exercise
- Where
- 4 sites in Germany, Netherlands and 2 more
- Volunteers
- 207 people
- Sponsor
- Goethe University
Overweight , Obesity, Type 2 Diabetes Mellitus (T2DM)
Phase 1 Clinical Study of MWN105 Injection in Healthy Chinese Volunteers
This study is a randomized, double-blind, placebo-controlled, single-dose and multiple-dose, dose-escalation phase I clinical trial, aiming to evaluate the safety, tolerability, pharmacokinetic and pharmacodynamic…
- Conditions
- Overweight , Obesity, Type 2 Diabetes Mellitus (T2DM), MASH - Metabolic Dysfunction-Associated Steatohepatitis
- Trial name
- NCT07801313
- Testing
- MWN105
- Where
- China
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Shanghai Minwei Biotechnology Co., Ltd
Abdominal Obesity, Metabolic Syndrome
Acupuncture in the Regulation of Dai Meridian for the Metabolism of Visceral Adipose Tissue in Abdominal Obese Patients
To evaluate the effectiveness of acupuncture therapy combined with healthy education for patients with abdominal obesity.
- Trial name
- NCT02427347
- Testing
- Acupuncture, Healthy education
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Dongfang Hospital Beijing University of Chinese Medicine
Obesity, Appetite Disorders
Impact of a Satiating Diet in Obese Men With a Low Satiety Phenotype
The global research project was organized as a clinical process starting with an evaluation aiming at the determination of a diagnosis pertaining to the degree of satiety signal capacity.
- Trial name
- NCT03128697
- Testing
- Satiating diet, Control diet
- Where
- 2 sites in Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Laval University
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