Clinical trials: Body Weight Management
Obesity, Obesity, Abdominal
Immunometabolic Effects of Non-drug Strategies in the Clinical Management of Obesity: Translational Study
Forty women aged between 18 and 75 years-old with a BMI> 30kg/m2 are recruited to participate in the evaluation of their medical management.
- Conditions
- Obesity, Obesity, Abdominal, Obesity, Visceral, Female
- Trial name
- PPAR-NAPAS (NCT04436419)
- Testing
- Alpha lipoic acid (plus full hospitalization)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Fauqué
Gout, Obesity (BMI>30)
Mazdutide for Weight Management and Gout in Adults With Obesity
This is a single-arm, open-label, pre-post controlled study to evaluate the effect of Mazdutide on the annualized flare rate (AFR) in adults with obesity and gout.
- Conditions
- Gout, Obesity (BMI>30), Hyperuricemia, Metabolic Syndrome
- Trial name
- NCT07824895
- Testing
- Mazdutide
- Volunteers
- 30 people
- Sponsor
- Hongwei Jiang
Overweight and Obesity
A Study Evulating DA-302168S Tablets in Overweight/Obese Subjects
The goal of this clinical trial is to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of continuous oral administration of DA-302168S tablets for 28 days in overweight/obese subjects.
- Trial name
- DA168 (NCT06541730)
- Testing
- DA-302168S
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Chendu DIAO Pharmaceutical Group CO., LTD.
Cardiovascular Diseases, Hyperlipidemia
Home-based Exercise for Management of HIV-associated Cardiovascular Disease Risk
Because of advances in drug treatment, people living with HIV/AIDS (PLWHA) are living longer, but are also at greater risk for cardiovascular disease (CVD) and diabetes.
- Conditions
- Cardiovascular Diseases, Hyperlipidemia, Obesity
- Trial name
- NCT01377064
- Testing
- Physical Activity Group, Standard Care Group
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of South Carolina
Overweight and Obesity, Weight Loss
Personalized Obesity Management - Matching Dietary Fibers and Microbial Enterotype
The overall aim of this 12-week randomized controlled trial is to investigate if a dietary fiber supplement rich in arabinoxylans (AX) affects weight loss success differently according to baseline gut microbiota composition in…
- Trial name
- POMFAME (NCT05260762)
- Testing
- Arabinoxylan, Control
- Where
- Denmark
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Obesity
Effect of Dapagliflozin/Metformin XR vs Monotherapies on Anthropometric Indicators in Obesity
Obesity has increased to alarming levels in the world. Currently it is estimated that it occurs in a third of the world's population and it is expected that by 2030, 20% of the world's adult population will suffer from obesity…
- Trial name
- NCT03710460
- Testing
- Dapagliflozin, Dapagliflozin plus Metformin XR, Metformin XR
- Where
- Mexico
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Guadalajara
Adolescent Obesity
Self-Weighing for Adolescents Seeking Obesity Treatment
99 patients age 12 to <18 years old with obesity (BMI >/=95th percentile), will be randomized to one of three treatment interventions: 1. Usual Care 2. Usual Care plus advice to weigh daily on simple scale 3.
- Trial name
- NCT04837586
- Testing
- Standard Care, Simple Scale, EHR-Connected Scale
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Minnesota
Stress, Fatigue
A Clinical Trial to Evaluate the Effects of a Herbal Tincture on Energy Levels, Weight Management, and Markers of Metabolic Health
This study will evaluate the effects of the Blue Burn Tincture on energy levels, weight management, and markers of metabolic health. It is a single-arm, hybrid trial involving 40 participants over a 12-week period.
- Trial name
- NCT06949540
- Testing
- Blue Burn Tincture
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Apothekary
Obesity
A Research Study on How Well Semaglutide Helps Children and Teenagers With Excess Body Weight Lose Weight
This study will look at how well semaglutide helps children and teenagers losing weight. This will be tested by comparing the effect on body weight in children and teenagers taking semaglutide in comparison to placebo, a "dummy"…
- Trial name
- STEP Young (NCT05726227)
- Testing
- Semaglutide
- Where
- 56 sites in United States, Austria and 8 more
- Volunteers
- 212 people
- Sponsor
- Novo Nordisk A/S
Obesity
A Pilot Study Evaluating a Clinically Managed Weight Loss Program
This is a pilot study evaluating a clinically managed weight loss program. The program consists of a 17-week weight loss program which involves a multidisciplinary team where personalized interventions are given to participants…
- Trial name
- NCT04290910
- Testing
- Weight Loss Program
- Where
- Canada
- Volunteers
- 43 people
- Sponsor
- University of Manitoba
Diabetes Mellitus, Type 2, Obesity
Effectiveness of a Weight Management Programme on Diabetes Remission in Obese Patients With Early Diabetes
The goal of this clinical trial is to determine the effectiveness of a weight management programme in primary care in achieving diabetes remission in obese patients with early diabetes.
- Trial name
- NCT05762120
- Testing
- Weight Management Programme
- Where
- Singapore
- Volunteers
- 120 people
- Sponsor
- National Healthcare Group Polyclinics
Obesity
Awareness, Care & Treatment In Obesity Management - An Observation in Asia Pacific
ACTION APAC is a cross-sectional, observational, descriptive, and exploratory survey-based study without collection of laboratory data. The study is not related to any specific treatment options or pharmaceutical product.
- Trial name
- ACTION-APAC (NCT05250427)
- Testing
- No treatment given
- Where
- 9 sites in Bangladesh, India and 7 more
- Volunteers
- 12,404 people
- Sponsor
- Novo Nordisk A/S
Gestational Diabetes, Gestational Weight Gain
Weight Gain Recommendations for Chinese Women With Gestational Diabetes Mellitus
The 2009 IOM recommendation value for weight gain during pregnancy is widely used. Due to the unclear relationship between gestational diabetes mellitus and weight gain during pregnancy when formulating this recommendation value…
- Trial name
- NCT04421053
- Testing
- prenatal care for women with GDM
- Where
- China
- Volunteers
- 4,050 people
- Sponsor
- Peking Union Medical College Hospital
Weight, Body
Effect of Synbiotic L. Fermentum Strains on Body Fat Mass
In this placebo-controlled trial the effect of a synbiotic consisting of three different strains of Lactobacillus fermentum and acacia gum (gum arabic) was compared with a probiotic formulation containing identical strains on…
- Trial name
- NCT05405205
- Testing
- synbiotic, probiotic
- Where
- Germany
- Volunteers
- 180 people
- Sponsor
- Slimbiotics GmbH
Overweight and Obesity
Inhibitory Control Adult Weight Management
The purpose of this pilot study is to explore the benefits of supplementing the WW (formerly Weight Watchers) online program with a cognitive training game (PolyRules!) among adults with overweight or obesity.
- Trial name
- NCT04747886
- Testing
- WW Only, WW + PolyRules!
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Type 2 Diabetes, Obesity
The Aboriginal Youth Mentorship Program
Building on the successes of a communal, relationship based approach to Aboriginal youth mentoring in an after school physical activity program (AYMP), the investigators are evaluating a peer-led approach for diabetes prevention.
- Trial name
- AYMP (NCT01820377)
- Testing
- Aboriginal Youth Mentorship Program
- Where
- Canada
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Obesity (Disorder), Child Obesity
Pharmacological Treatment - An Overview of Its Role in Managing Childhood Obesity
The aim of the study is to examine the effects of pharmacological treatment for obesity on BMI trajectories and metabolic markers among patients in routine clinical care. A retrospective observational study.
- Trial name
- NCT07304141
- Testing
- Liraglutide 3 mg (Saxenda)
- Where
- Sweden
- Volunteers
- 128 people
- Sponsor
- Göteborg University
Obesity, Diet Therapy
Lifestyle Interventions for Expectant Mothers (LIFE-Moms Phoenix) - Phoenix
Background: LIFE-Moms (Lifestyle Interventions for Expectant Moms) is a national project that is studying pregnant women who are overweight or obese.
- Conditions
- Obesity, Diet Therapy, Diabetes Type 2
- Trial name
- NCT01812694
- Testing
- Enhanced standard care, Intensive lifestyle intervention
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Obesity
Effects of Co-administration of Canagliflozin 300 mg and Phentermine 15 mg With Placebo in the Treatment of Non-Diabetic Overweight and Obese Participants
The purpose of this study is to compare the effects of canagliflozin and phentermine to those of placebo to promote on a change in body weight over a 26 week period.
- Trial name
- NCT02243202
- Testing
- Canagliflozin, Phentermine
- Where
- 17 sites in United States
- Volunteers
- 335 people
- Sponsor
- Janssen Research & Development, LLC
Obesity, Adolescent
Increased Protein at Breakfast for Weight Management in Overweight Adolescents
Adolescent obesity, negatively affecting the lives of over 18 million (34%) US adolescents, continues to be a major public health concern due to the increased risk of developing chronic diseases, including type 2 diabetes.
- Trial name
- NCT03146442
- Testing
- Breakfast
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin